# ErmineJ results file # Created Sat May 11 14:00:01 PDT 2013 # If you use this file in your research, please cite: # Lee H.K., Braynen W., Keshav K. and Pavlidis P. (2005) # ErmineJ: Tool for functional analysis of gene expression data sets. BMC Bioinformatics 6:269 # See http://www.chibi.ubc.ca/ermineJ for more information # Do not edit this file or you may not be able to reload it into ErmineJ. Edit a copy instead. # Start output of analysis run: pardo-oct4interactionswithoutoct4 # Settings scoreThreshold = 1.0 maxClassSize = 200 minClassSize = 20 rawFile = scoreFile = QuickList.oct4-interactorwithoutoct4.txt scoreCol = 2 classFile = go_daily-termdb.rdf-xml.gz bigIsBetter = false doLog = true geneRepTreatment = MEAN annotFile = Generic_mouse_noParents.an.txt.gz annotFormat = DEFAULT classScoreMethod = ORA multifuncCorr = true useGOMolecularFunction = false useGOBiologicalProcess = true useGOCellularComponent = false useUserDefinedGroups = false multifunctionalityCorrelation=0.1100 multifunctionalityEnrichment=0.6458 multifunctionalityEnrichmentPvalue=1.496e-06 numAboveThreshold=86 #!---- !# runName=pardo-oct4interactionswithoutoct4 # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue MFPvalue CorrectedMFPvalue Multifuntionality Same as GeneMembers ! chromatin remodeling GO:0006338 68 68 8.000 9.582E-10 2.097E-06 1.637E-05 0.03582126 0.841 ! DNA recombination GO:0006310 152 144 10.000 1.336E-09 1.462E-06 5.724E-04 0.31309941 0.935 ! DNA conformation change GO:0071103 135 131 9.000 1.028E-08 7.497E-06 3.713E-04 0.27081525 0.916 ! DNA packaging GO:0006323 105 101 8.000 2.313E-08 1.265E-05 1.285E-03 0.25554113 0.711 ! negative regulation of gene expression, epigenetic GO:0045814 22 22 5.000 4.896E-08 2.142E-05 0.09795133 1.000 0.724 ! chromatin assembly or disassembly GO:0006333 88 84 7.000 1.284E-07 4.682E-05 6.447E-04 0.2821406 0.637 ! histone acetylation GO:0016573 90 85 7.000 1.394E-07 4.357E-05 6.742E-04 0.24585611 0.931 ! internal peptidyl-lysine acetylation GO:0018393 92 87 7.000 1.638E-07 4.479E-05 7.359E-04 0.23003082 0.933 ! peptidyl-lysine acetylation GO:0018394 94 89 7.000 1.917E-07 4.66E-05 8.016E-04 0.21922765 0.934 ! internal protein amino acid acetylation GO:0006475 96 91 7.000 2.235E-07 4.889E-05 8.712E-04 0.21180515 0.936 ! protein acetylation GO:0006473 109 104 7.000 5.585E-07 1.111E-04 1.432E-03 0.26102362 0.936 ! DNA replication GO:0006260 165 159 8.000 7.788E-07 1.42E-04 1.005E-04 0.10995367 0.913 ! histone H4 acetylation GO:0043967 44 42 5.000 1.47E-06 2.473E-04 9.91E-04 0.21683205 0.714 ! protein acylation GO:0043543 129 124 7.000 1.836E-06 2.869E-04 2.722E-03 0.45810068 0.930 ! double-strand break repair GO:0006302 90 84 6.000 2.647E-06 3.861E-04 0.05879183 1.000 0.950 ! peptidyl-lysine modification GO:0018205 138 132 7.000 2.789E-06 3.814E-04 3.408E-03 0.53265861 0.943 ! DNA alkylation GO:0006305 34 34 4.000 1.851E-05 2.382E-03 0.14731757 1.000 0.761 GO:0006306|DNA methylation, ! DNA methylation GO:0006306 34 34 4.000 1.851E-05 2.382E-03 0.14731757 1.000 0.761 GO:0006305|DNA alkylation, ! protein-DNA complex subunit organization GO:0071824 85 82 5.000 4.071E-05 4.949E-03 0.05634171 1.000 0.659 ! positive regulation of viral reproduction GO:0048524 42 42 4.000 4.341E-05 4.999E-03 1.000 1.000 0.823 ! regulation of gene expression, epigenetic GO:0040029 147 142 6.000 5.37E-05 5.874E-03 0.14247656 1.000 0.941 ! gene silencing GO:0016458 98 92 5.000 7.074E-05 7.371E-03 0.3507353 1.000 0.934 ! DNA modification GO:0006304 52 52 4.000 1.013E-04 0.01007817 0.21640201 1.000 0.832 ! modulation by host of viral transcription GO:0043921 20 20 3.000 1.06E-04 0.01008242 1.000 1.000 0.800 GO:0052312|modulation of transcription in other organism involved in symbiotic interaction, GO:0052472|modulation by host of symbiont transcription, ! modulation of transcription in other organism involved in symbiotic interaction GO:0052312 20 20 3.000 1.06E-04 0.01008242 1.000 1.000 0.800 GO:0043921|modulation by host of viral transcription, GO:0052472|modulation by host of symbiont transcription, ! modulation by host of symbiont transcription GO:0052472 20 20 3.000 1.06E-04 0.01008242 1.000 1.000 0.800 GO:0052312|modulation of transcription in other organism involved in symbiotic interaction, GO:0043921|modulation by host of viral transcription, ! ATP catabolic process GO:0006200 112 111 5.000 1.72E-04 0.01568179 0.40630258 1.000 0.949 ! regulation of viral transcription GO:0046782 27 27 3.000 2.656E-04 0.02324404 1.000 1.000 0.821 ! modification by host of symbiont morphology or physiology GO:0051851 27 27 3.000 2.656E-04 0.02235004 1.000 1.000 0.844 ! chromatin assembly GO:0031497 72 68 4.000 2.88E-04 0.0233387 0.27314776 1.000 0.520 ! regulation of viral reproduction GO:0050792 71 70 4.000 3.22E-04 0.02515894 1.000 1.000 0.851 ! protein-DNA complex assembly GO:0065004 73 70 4.000 3.22E-04 0.02429139 0.27994905 1.000 0.550 ! neural tube closure GO:0001843 72 72 4.000 3.587E-04 0.02616115 4.656E-03 0.67909524 0.870 ! nucleosome organization GO:0034728 75 72 4.000 3.587E-04 0.02531725 0.04466928 1.000 0.584 ! fat cell differentiation GO:0045444 72 72 4.000 3.587E-04 0.02452608 0.04466928 1.000 0.819 ! tube closure GO:0060606 73 73 4.000 3.782E-04 0.02507256 4.839E-03 0.66172063 0.873 ! cellular response to ionizing radiation GO:0071479 33 31 3.000 4.027E-04 0.02591306 0.13523226 1.000 0.776 ! primary neural tube formation GO:0014020 77 77 4.000 4.635E-04 0.02897839 5.616E-03 0.68260351 0.878 ! appendage morphogenesis GO:0035107 139 139 5.000 4.873E-04 0.02961429 0.13768992 1.000 0.968 GO:0035108|limb morphogenesis, ! limb morphogenesis GO:0035108 139 139 5.000 4.873E-04 0.02961429 0.13768992 1.000 0.968 GO:0035107|appendage morphogenesis, ! ATP metabolic process GO:0046034 141 140 5.000 5.035E-04 0.02977244 0.48217903 1.000 0.953 ! cellular component disassembly at cellular level GO:0071845 83 83 4.000 6.162E-04 0.03548135 0.05756216 1.000 0.882 ! appendage development GO:0048736 149 149 5.000 6.683E-04 0.03749076 0.15377991 1.000 0.962 GO:0060173|limb development, ! limb development GO:0060173 149 149 5.000 6.683E-04 0.03749076 0.15377991 1.000 0.962 GO:0048736|appendage development, ! cellular component disassembly GO:0022411 85 85 4.000 6.742E-04 0.03687842 0.06003061 1.000 0.884 ! telomere maintenance GO:0000723 37 37 3.000 6.821E-04 0.03640211 1.000 1.000 0.816 ! telomere organization GO:0032200 38 38 3.000 7.381E-04 0.03845161 1.000 1.000 0.818 ! interaction with symbiont GO:0051702 38 38 3.000 7.381E-04 0.03755739 1.000 1.000 0.874 ! neural tube formation GO:0001841 92 92 4.000 9.076E-04 0.04513314 9.17E-03 1.000 0.969 ! hindlimb morphogenesis GO:0035137 42 42 3.000 9.91E-04 0.0481849 0.17873499 1.000 0.840 ! modification of morphology or physiology of other organism GO:0035821 43 43 3.000 1.062E-03 0.05050256 1.000 1.000 0.892 GO:0051817|modification of morphology or physiology of other organism involved in symbiotic interaction, ! histone H3 acetylation GO:0043966 47 43 3.000 1.062E-03 0.04942804 0.01720985 1.000 0.701 ! modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 43 43 3.000 1.062E-03 0.05050256 1.000 1.000 0.892 GO:0035821|modification of morphology or physiology of other organism, ! regulation of interphase of mitotic cell cycle GO:2000602 109 107 4.000 1.59E-03 0.07246691 0.01378849 1.000 0.968 ! embryonic epithelial tube formation GO:0001838 109 109 4.000 1.702E-03 0.07598828 0.01448734 1.000 0.982 GO:0072175|epithelial tube formation, ! epithelial tube formation GO:0072175 109 109 4.000 1.702E-03 0.07598828 0.01448734 1.000 0.982 GO:0001838|embryonic epithelial tube formation, ! response to osmotic stress GO:0006970 55 54 3.000 2.057E-03 0.08999606 0.2237279 1.000 0.793 ! tube formation GO:0035148 116 116 4.000 2.137E-03 0.09167416 0.01708968 1.000 0.982 ! nucleosome assembly GO:0006334 58 55 3.000 2.168E-03 0.09122045 0.22736542 1.000 0.293 ! embryonic limb morphogenesis GO:0030326 117 117 4.000 2.205E-03 0.0910159 0.42285326 1.000 0.966 GO:0035113|embryonic appendage morphogenesis, ! embryonic appendage morphogenesis GO:0035113 117 117 4.000 2.205E-03 0.0910159 0.42285326 1.000 0.966 GO:0030326|embryonic limb morphogenesis, ! positive regulation of reproductive process GO:2000243 59 59 3.000 2.651E-03 0.10739844 1.000 1.000 0.885 ! macromolecule methylation GO:0043414 134 128 4.000 3.052E-03 0.1214075 0.45202038 1.000 0.936 ! cellular response to radiation GO:0071478 67 65 3.000 3.491E-03 0.13638036 0.26282661 1.000 0.871 ! morphogenesis of embryonic epithelium GO:0016331 133 133 4.000 3.502E-03 0.13441128 0.02443146 1.000 0.987 ! regulation of reproductive process GO:2000241 135 134 4.000 3.597E-03 0.13568001 1.000 1.000 0.990 ! neural tube development GO:0021915 137 136 4.000 3.792E-03 0.14062534 0.02587795 1.000 0.973 ! blastocyst growth GO:0001832 20 20 2.000 3.881E-03 0.14153781 0.08945337 1.000 0.563 ! hyperosmotic salinity response GO:0042538 20 20 2.000 3.881E-03 0.13921752 1.000 1.000 0.337 ! negative regulation of smoothened signaling pathway GO:0045879 20 20 2.000 3.881E-03 0.13697207 0.08945337 1.000 0.664 ! protein homotrimerization GO:0070207 20 20 2.000 3.881E-03 0.13479792 1.000 1.000 0.646 ! cellular hyperosmotic response GO:0071474 20 20 2.000 3.881E-03 0.1326917 1.000 1.000 0.321 ! regulation of androgen receptor signaling pathway GO:0060765 21 21 2.000 4.277E-03 0.1439663 1.000 1.000 0.772 ! blastocyst development GO:0001824 71 71 3.000 4.477E-03 0.14840448 0.28332607 1.000 0.805 ! response to X-ray GO:0010165 22 22 2.000 4.69E-03 0.15317127 1.000 1.000 0.730 ! anatomical structure homeostasis GO:0060249 145 145 4.000 4.761E-03 0.15317618 0.49425547 1.000 0.981 ! reciprocal meiotic recombination GO:0007131 23 23 2.000 5.122E-03 0.1624042 1.000 1.000 0.720 GO:0035825|reciprocal DNA recombination, ! negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 23 23 2.000 5.122E-03 0.16008414 1.000 1.000 0.797 ! reciprocal DNA recombination GO:0035825 23 23 2.000 5.122E-03 0.1624042 1.000 1.000 0.720 GO:0007131|reciprocal meiotic recombination, ! stem cell differentiation GO:0048863 150 149 4.000 5.24E-03 0.16147412 0.50371583 1.000 0.959 ! RNA stabilization GO:0043489 24 24 2.000 5.57E-03 0.16927333 5.57E-03 0.71692235 0.667 GO:0048255|mRNA stabilization, ! mRNA stabilization GO:0048255 24 24 2.000 5.57E-03 0.16927333 5.57E-03 0.71692235 0.667 GO:0043489|RNA stabilization, ! genetic imprinting GO:0071514 25 25 2.000 6.036E-03 0.18092433 0.1105515 1.000 0.690 ! telencephalon development GO:0021537 158 157 4.000 6.293E-03 0.18607717 0.1669041 1.000 0.990 ! epidermal cell differentiation GO:0009913 81 81 3.000 6.463E-03 0.18854518 1.000 1.000 0.760 ! apoptotic nuclear change GO:0030262 26 26 2.000 6.52E-03 0.18769617 0.11471278 1.000 0.717 ! chromosome condensation GO:0030261 27 27 2.000 7.02E-03 0.1994755 0.11885481 1.000 0.507 ! cellular response to osmotic stress GO:0071470 27 27 2.000 7.02E-03 0.19691812 1.000 1.000 0.586 ! hyperosmotic response GO:0006972 28 28 2.000 7.537E-03 0.2087497 1.000 1.000 0.574 ! cellular component disassembly involved in apoptosis GO:0006921 29 29 2.000 8.071E-03 0.22074235 0.1270815 1.000 0.746 ! response to salt stress GO:0009651 30 30 2.000 8.621E-03 0.23288567 1.000 1.000 0.646 ! regulation of G2/M transition of mitotic cell cycle GO:0010389 31 30 2.000 8.621E-03 0.2300456 0.13116633 1.000 0.753 ! response to ionizing radiation GO:0010212 99 91 3.000 8.901E-03 0.23463295 0.3476724 1.000 0.955 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 32 32 2.000 9.771E-03 0.25451896 1.000 1.000 0.859 GO:0016444|somatic cell DNA recombination, ! somatic cell DNA recombination GO:0016444 32 32 2.000 9.771E-03 0.25451896 1.000 1.000 0.859 GO:0002562|somatic diversification of immune receptors via germline recombination within a single locus, ! stem cell maintenance GO:0019827 96 95 3.000 0.01000682 0.25758728 0.35983899 1.000 0.965 ! olfactory bulb development GO:0021772 34 34 2.000 0.01098536 0.27948804 0.14731757 1.000 0.792 ! regulation of mRNA stability GO:0043488 34 34 2.000 0.01098536 0.27627553 0.01098536 1.000 0.707 ! somatic diversification of immune receptors GO:0002200 35 35 2.000 0.01161608 0.28881806 1.000 1.000 0.850 ! olfactory lobe development GO:0021988 35 35 2.000 0.01161608 0.28557291 0.15130879 1.000 0.802 ! regulation of S phase GO:0033261 36 35 2.000 0.01161608 0.28239988 0.01161608 1.000 0.739 ! positive regulation of DNA binding GO:0043388 35 35 2.000 0.01161608 0.27929658 1.000 1.000 0.866 ! developmental pigmentation GO:0048066 37 35 2.000 0.01161608 0.27626075 0.01161608 1.000 0.819 ! stem cell development GO:0048864 102 101 3.000 0.01181002 0.27785303 0.37766954 1.000 0.968 ! symbiosis, encompassing mutualism through parasitism GO:0044403 103 103 3.000 0.01244991 0.28979153 1.000 1.000 0.994 GO:0044419|interspecies interaction between organisms, ! interspecies interaction between organisms GO:0044419 103 103 3.000 0.01244991 0.28979153 1.000 1.000 0.994 GO:0044403|symbiosis, encompassing mutualism through parasitism, ! double-strand break repair via homologous recombination GO:0000724 42 37 2.000 0.01292412 0.29766278 0.01292412 1.000 0.593 ! positive regulation of histone modification GO:0031058 38 37 2.000 0.01292412 0.29456212 1.000 1.000 0.857 ! forelimb morphogenesis GO:0035136 37 37 2.000 0.01292412 0.2915254 0.15923592 1.000 0.797 ! protein trimerization GO:0070206 37 37 2.000 0.01292412 0.28855065 1.000 1.000 0.665 ! recombinational repair GO:0000725 44 38 2.000 0.01360112 0.3005984 0.01360112 1.000 0.602 ! regulation of RNA stability GO:0043487 38 38 2.000 0.01360112 0.29759242 0.01360112 1.000 0.725 ! regulation of protein stability GO:0031647 110 107 3.000 0.01378849 0.298705 0.39500907 1.000 0.959 ! response to nutrient GO:0007584 110 108 3.000 0.01413544 0.30321903 1.000 1.000 0.957 ! response to insulin stimulus GO:0032868 110 109 3.000 0.01448734 0.3077504 0.40068212 1.000 0.985 ! positive regulation of mitotic cell cycle GO:0045931 41 40 2.000 0.01500032 0.31558361 0.01500032 1.000 0.860 ! cellular response to abiotic stimulus GO:0071214 115 112 3.000 0.01557277 0.32450681 0.40909324 1.000 0.970 ! epidermis morphogenesis GO:0048730 41 41 2.000 0.01572222 0.32453026 1.000 1.000 0.845 ! sister chromatid segregation GO:0000819 44 42 2.000 0.01645878 0.33655889 0.17873499 1.000 0.757 ! cellular macromolecular complex disassembly GO:0034623 42 42 2.000 0.01645878 0.33344261 0.17873499 1.000 0.791 ! regulation of DNA recombination GO:0000018 44 43 2.000 0.01720985 0.34546011 1.000 1.000 0.848 ! macromolecular complex disassembly GO:0032984 44 44 2.000 0.01797529 0.35754485 0.18640886 1.000 0.804 ! regulation of smoothened signaling pathway GO:0008589 46 46 2.000 0.01954868 0.38533788 0.19401186 1.000 0.815 ! hippocampus development GO:0021766 47 46 2.000 0.01954868 0.38189736 0.19401186 1.000 0.840 ! positive regulation of chromosome organization GO:2001252 48 47 2.000 0.02035633 0.39415625 1.000 1.000 0.883 ! cardiac chamber development GO:0003205 125 125 3.000 0.02079555 0.39912855 0.4442134 1.000 0.998 ! regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 48 48 2.000 0.02117777 0.40293011 1.000 1.000 0.864 ! ventricular septum development GO:0003281 49 49 2.000 0.02201285 0.41520786 0.20528487 1.000 0.864 ! chromosome segregation GO:0007059 133 129 3.000 0.02257324 0.42213895 0.12201547 1.000 0.935 ! embryonic digit morphogenesis GO:0042733 51 51 2.000 0.02372335 0.43988723 1.000 1.000 0.843 ! meiosis GO:0007126 133 132 3.000 0.02395936 0.44053006 0.46226131 1.000 0.931 GO:0051327|M phase of meiotic cell cycle, ! M phase of meiotic cell cycle GO:0051327 133 132 3.000 0.02395936 0.44053006 0.46226131 1.000 0.931 GO:0007126|meiosis, ! cellular response to growth factor stimulus GO:0071363 136 134 3.000 0.02490859 0.45416671 0.46731061 1.000 0.968 ! protein import GO:0017038 137 135 3.000 0.02539076 0.45913205 0.13136619 1.000 0.948 ! meiotic cell cycle GO:0051321 136 135 3.000 0.02539076 0.45536867 0.46981766 1.000 0.931 ! DNA-dependent DNA replication GO:0006261 55 55 2.000 0.02730184 0.48566194 1.000 1.000 0.769 ! response to heat GO:0009408 56 55 2.000 0.02730184 0.48174531 0.02730184 1.000 0.730 ! response to growth factor stimulus GO:0070848 148 146 3.000 0.03102573 0.54307432 0.49663713 1.000 0.972 ! positive regulation of neurogenesis GO:0050769 153 150 3.000 0.03322471 0.57694969 1.000 1.000 0.988 ! limbic system development GO:0021761 63 62 2.000 0.03404665 0.58656741 0.25236062 1.000 0.869 ! spindle organization GO:0007051 68 63 2.000 0.03505819 0.59927585 0.03505819 1.000 0.755 ! liver development GO:0001889 64 64 2.000 0.03608133 0.61198416 1.000 1.000 0.885 ! transforming growth factor beta receptor signaling pathway GO:0007179 64 64 2.000 0.03608133 0.60727659 1.000 1.000 0.861 ! osteoblast differentiation GO:0001649 65 65 2.000 0.03711596 0.61992155 0.03711596 1.000 0.859 ! cardiac septum development GO:0003279 65 65 2.000 0.03711596 0.61522518 0.26282661 1.000 0.891 ! protein stabilization GO:0050821 67 65 2.000 0.03711596 0.61059942 1.000 1.000 0.853 ! negative regulation of DNA metabolic process GO:0051053 66 65 2.000 0.03711596 0.60604271 1.000 1.000 0.874 ! hepaticobiliary system development GO:0061008 66 66 2.000 0.03816194 0.61850617 1.000 1.000 0.888 ! myeloid cell differentiation GO:0030099 162 160 3.000 0.03906849 0.62854308 0.52883935 1.000 0.956 ! response to peptide hormone stimulus GO:0043434 161 160 3.000 0.03906849 0.62395518 0.52883935 1.000 0.969 ! response to retinoic acid GO:0032526 69 67 2.000 0.03921915 0.62182252 1.000 1.000 0.823 ! meiosis I GO:0007127 68 68 2.000 0.04028747 0.6341653 1.000 1.000 0.846 ! ribonucleoside metabolic process GO:0009119 69 68 2.000 0.04028747 0.62963555 1.000 1.000 0.888 ! regulation of histone modification GO:0031056 69 68 2.000 0.04028747 0.62517005 1.000 1.000 0.891 ! response to vitamin A GO:0033189 71 69 2.000 0.04136676 0.63739765 1.000 1.000 0.820 ! pigmentation GO:0043473 72 69 2.000 0.04136676 0.63294032 0.04136676 1.000 0.870 ! ossification GO:0001503 168 168 3.000 0.04409545 0.6700058 0.18525059 1.000 0.954 ! erythrocyte differentiation GO:0030218 73 72 2.000 0.04466928 0.67404397 1.000 1.000 0.851 ! regulation of DNA binding GO:0051101 72 72 2.000 0.04466928 0.66942723 1.000 1.000 0.892 ! homeostasis of number of cells GO:0048872 175 171 3.000 0.04606009 0.68557461 0.55270509 1.000 0.964 ! positive regulation of nucleocytoplasmic transport GO:0046824 78 77 2.000 0.05038171 0.74483236 0.30326193 1.000 0.898 ! developmental growth GO:0048589 179 179 3.000 0.05150806 0.7563734 0.56930764 1.000 0.987 ! regulation of Wnt receptor signaling pathway GO:0030111 184 180 3.000 0.0522102 0.76157284 0.57133966 1.000 0.963 ! erythrocyte homeostasis GO:0034101 81 80 2.000 0.05392893 0.78143375 1.000 1.000 0.862 ! nucleoside metabolic process GO:0009116 83 81 2.000 0.0551306 0.79359047 1.000 1.000 0.891 ! vesicle organization GO:0016050 85 82 2.000 0.05634171 0.80572334 0.31945567 1.000 0.874 ! cellular response to insulin stimulus GO:0032869 83 82 2.000 0.05634171 0.80049137 0.31945567 1.000 0.884 ! response to vitamin GO:0033273 84 82 2.000 0.05634171 0.79532691 1.000 1.000 0.950 ! positive regulation of cell development GO:0010720 191 187 3.000 0.05725481 0.80303538 1.000 1.000 0.993 ! protein import into nucleus GO:0006606 86 85 2.000 0.06003061 0.83660488 0.06003061 1.000 0.943 ! response to temperature stimulus GO:0009266 86 85 2.000 0.06003061 0.83130991 0.06003061 1.000 0.943 ! regulation of myeloid leukocyte differentiation GO:0002761 87 86 2.000 0.06127838 0.84325222 0.33214235 1.000 0.895 ! epidermis development GO:0008544 194 194 3.000 0.06252273 0.85499827 1.000 1.000 0.940 ! positive regulation of binding GO:0051099 88 87 2.000 0.06253505 0.84985525 1.000 1.000 0.891 ! nuclear import GO:0051170 88 87 2.000 0.06253505 0.84460923 0.06253505 1.000 0.942 ! pallium development GO:0021543 93 92 2.000 0.06894802 0.92551079 0.3507353 1.000 0.898 ! female pregnancy GO:0007565 96 96 2.000 0.07422762 0.99030507 0.36284543 1.000 0.748 ! response to UV GO:0009411 99 96 2.000 0.07422762 0.98430322 0.36284543 1.000 0.974 ! aging GO:0007568 98 98 2.000 0.0769149 1.000 0.36881649 1.000 0.982 ! positive regulation of intracellular protein transport GO:0090316 102 99 2.000 0.07827006 1.000 0.37178125 1.000 0.902 ! cellular response to peptide hormone stimulus GO:0071375 101 100 2.000 0.07963277 1.000 0.37473225 1.000 0.984 ! cardiac ventricle development GO:0003231 104 104 2.000 0.08515712 1.000 0.38639984 1.000 0.997 ! positive regulation of intracellular transport GO:0032388 109 105 2.000 0.08655611 1.000 0.38928295 1.000 0.996 ! regulation of chromosome organization GO:0033044 108 107 2.000 0.08937489 1.000 1.000 1.000 0.995 ! androgen receptor signaling pathway GO:0030521 20 20 1.000 0.08945337 1.000 0.08945337 1.000 0.519 ! negative regulation of histone modification GO:0031057 20 20 1.000 0.08945337 1.000 1.000 1.000 0.778 ! hemopoietic stem cell differentiation GO:0060218 20 20 1.000 0.08945337 1.000 1.000 1.000 0.394 ! lung cell differentiation GO:0060479 20 20 1.000 0.08945337 1.000 1.000 1.000 0.755 ! morphogenesis of an epithelial fold GO:0060571 20 20 1.000 0.08945337 1.000 0.08945337 1.000 0.796 ! adipose tissue development GO:0060612 21 20 1.000 0.08945337 1.000 0.08945337 1.000 0.721 ! metanephric nephron development GO:0072210 20 20 1.000 0.08945337 1.000 1.000 1.000 0.875 ! regulation of DNA-dependent DNA replication GO:0090329 21 20 1.000 0.08945337 1.000 0.08945337 1.000 0.716 ! regulation of glycolysis GO:0006110 21 21 1.000 0.0937122 1.000 1.000 1.000 0.820 ! signal transduction involved in regulation of gene expression GO:0023019 21 21 1.000 0.0937122 1.000 1.000 1.000 0.775 ! cellular response to heat GO:0034605 21 21 1.000 0.0937122 1.000 0.0937122 1.000 0.224 ! vascular smooth muscle cell differentiation GO:0035886 21 21 1.000 0.0937122 1.000 1.000 1.000 0.827 ! regulation of protein export from nucleus GO:0046825 21 21 1.000 0.0937122 1.000 0.0937122 1.000 0.661 ! negative regulation of protein kinase B signaling cascade GO:0051898 21 21 1.000 0.0937122 1.000 1.000 1.000 0.789 ! heart trabecula morphogenesis GO:0061384 21 21 1.000 0.0937122 1.000 1.000 1.000 0.825 ! nephron epithelium morphogenesis GO:0072088 21 21 1.000 0.0937122 1.000 1.000 1.000 0.863 ! pyrimidine nucleotide biosynthetic process GO:0006221 22 22 1.000 0.09795133 1.000 1.000 1.000 0.808 GO:0072528|pyrimidine-containing compound biosynthetic process, ! drug metabolic process GO:0017144 22 22 1.000 0.09795133 1.000 1.000 1.000 0.720 ! regulation of catenin import into nucleus GO:0035412 22 22 1.000 0.09795133 1.000 0.09795133 1.000 0.789 ! cellular response to interferon-beta GO:0035458 22 22 1.000 0.09795133 1.000 0.09795133 1.000 0.458 ! nucleus localization GO:0051647 22 22 1.000 0.09795133 1.000 0.09795133 1.000 0.687 ! trabecula formation GO:0060343 22 22 1.000 0.09795133 1.000 1.000 1.000 0.818 ! nephron morphogenesis GO:0072028 22 22 1.000 0.09795133 1.000 1.000 1.000 0.868 ! pyrimidine-containing compound biosynthetic process GO:0072528 22 22 1.000 0.09795133 1.000 1.000 1.000 0.808 GO:0006221|pyrimidine nucleotide biosynthetic process, ! regulation of protein deacetylation GO:0090311 22 22 1.000 0.09795133 1.000 1.000 1.000 0.759 ! positive regulation of cell cycle process GO:0090068 115 113 2.000 0.09799109 1.000 0.09799109 1.000 0.993 ! melanocyte differentiation GO:0030318 24 23 1.000 0.10217087 1.000 0.10217087 1.000 0.744 ! DNA duplex unwinding GO:0032508 23 23 1.000 0.10217087 1.000 0.10217087 1.000 0.714 ! negative regulation of cytokine biosynthetic process GO:0042036 23 23 1.000 0.10217087 1.000 1.000 1.000 0.761 ! negative regulation of fibroblast proliferation GO:0048147 23 23 1.000 0.10217087 1.000 0.10217087 1.000 0.742 ! cellular response to vitamin A GO:0071299 23 23 1.000 0.10217087 1.000 1.000 1.000 0.779 GO:0071300|cellular response to retinoic acid, ! cellular response to retinoic acid GO:0071300 23 23 1.000 0.10217087 1.000 1.000 1.000 0.779 GO:0071299|cellular response to vitamin A, ! positive regulation of cell cycle GO:0045787 120 118 2.000 0.10534367 1.000 0.10534367 1.000 0.995 ! meiotic chromosome segregation GO:0045132 24 24 1.000 0.1063709 1.000 1.000 1.000 0.736 ! pyrimidine ribonucleoside metabolic process GO:0046131 24 24 1.000 0.1063709 1.000 1.000 1.000 0.817 ! homeostasis of number of cells within a tissue GO:0048873 24 24 1.000 0.1063709 1.000 0.1063709 1.000 0.663 ! pigment cell differentiation GO:0050931 25 24 1.000 0.1063709 1.000 0.1063709 1.000 0.760 ! immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 25 25 1.000 0.1105515 1.000 1.000 1.000 0.827 ! nucleobase metabolic process GO:0009112 25 25 1.000 0.1105515 1.000 1.000 1.000 0.737 ! somatic recombination of immunoglobulin gene segments GO:0016447 25 25 1.000 0.1105515 1.000 1.000 1.000 0.832 ! osteoclast differentiation GO:0030316 25 25 1.000 0.1105515 1.000 0.1105515 1.000 0.731 ! DNA geometric change GO:0032392 25 25 1.000 0.1105515 1.000 0.1105515 1.000 0.726 ! embryonic camera-type eye morphogenesis GO:0048596 25 25 1.000 0.1105515 1.000 1.000 1.000 0.839 ! negative regulation of response to cytokine stimulus GO:0060761 26 25 1.000 0.1105515 1.000 1.000 1.000 0.822 ! negative regulation of ERK1 and ERK2 cascade GO:0070373 25 25 1.000 0.1105515 1.000 1.000 1.000 0.748 ! cellular response to vitamin GO:0071295 25 25 1.000 0.1105515 1.000 1.000 1.000 0.803 ! protein localization to nucleus GO:0034504 125 123 2.000 0.11284137 1.000 0.11284137 1.000 0.947 ! protein O-linked glycosylation GO:0006493 26 26 1.000 0.11471278 1.000 1.000 1.000 0.520 ! negative regulation of endothelial cell migration GO:0010596 27 26 1.000 0.11471278 1.000 1.000 1.000 0.780 ! regulation of myoblast differentiation GO:0045661 26 26 1.000 0.11471278 1.000 0.11471278 1.000 0.787 ! lung epithelium development GO:0060428 26 26 1.000 0.11471278 1.000 1.000 1.000 0.818 ! cellular modified amino acid metabolic process GO:0006575 127 125 2.000 0.11587873 1.000 0.4442134 1.000 0.973 ! regulation of S phase of mitotic cell cycle GO:0007090 28 27 1.000 0.11885481 1.000 0.11885481 1.000 0.687 ! multicellular organismal aging GO:0010259 27 27 1.000 0.11885481 1.000 1.000 1.000 0.761 ! histone deacetylation GO:0016575 27 27 1.000 0.11885481 1.000 1.000 1.000 0.718 ! regulation of histone acetylation GO:0035065 27 27 1.000 0.11885481 1.000 1.000 1.000 0.808 ! response to interferon-beta GO:0035456 27 27 1.000 0.11885481 1.000 0.11885481 1.000 0.539 ! nephron epithelium development GO:0072009 27 27 1.000 0.11885481 1.000 1.000 1.000 0.879 ! regulation of canonical Wnt receptor signaling pathway GO:0060828 130 127 2.000 0.11893697 1.000 0.44943017 1.000 0.971 ! placenta development GO:0001890 128 128 2.000 0.12047373 1.000 0.45202038 1.000 0.968 ! regulation of protein import into nucleus GO:0042306 130 128 2.000 0.12047373 1.000 0.45202038 1.000 0.998 ! blastocyst formation GO:0001825 28 28 1.000 0.12297769 1.000 1.000 1.000 0.739 ! B cell activation involved in immune response GO:0002312 28 28 1.000 0.12297769 1.000 1.000 1.000 0.844 ! pyrimidine nucleoside metabolic process GO:0006213 28 28 1.000 0.12297769 1.000 1.000 1.000 0.827 ! pyrimidine nucleotide metabolic process GO:0006220 28 28 1.000 0.12297769 1.000 1.000 1.000 0.832 ! base-excision repair GO:0006284 28 28 1.000 0.12297769 1.000 1.000 1.000 0.688 ! somatic diversification of immunoglobulins GO:0016445 28 28 1.000 0.12297769 1.000 1.000 1.000 0.820 ! regulation of histone methylation GO:0031060 29 28 1.000 0.12297769 1.000 1.000 1.000 0.788 ! regulation of Rac protein signal transduction GO:0035020 28 28 1.000 0.12297769 1.000 1.000 1.000 0.730 ! cell cycle checkpoint GO:0000075 136 130 2.000 0.12356212 1.000 0.45716472 1.000 0.951 ! lactation GO:0007595 29 29 1.000 0.1270815 1.000 1.000 1.000 0.830 ! regulation of phosphatidylinositol 3-kinase activity GO:0043551 29 29 1.000 0.1270815 1.000 1.000 1.000 0.834 ! regulation of oligodendrocyte differentiation GO:0048713 30 29 1.000 0.1270815 1.000 1.000 1.000 0.788 ! regulation of peptidyl-lysine acetylation GO:2000756 29 29 1.000 0.1270815 1.000 1.000 1.000 0.823 ! regulation of carbohydrate catabolic process GO:0043470 30 30 1.000 0.13116633 1.000 1.000 1.000 0.836 GO:0043471|regulation of cellular carbohydrate catabolic process, ! regulation of cellular carbohydrate catabolic process GO:0043471 30 30 1.000 0.13116633 1.000 1.000 1.000 0.836 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of muscle adaptation GO:0043502 30 30 1.000 0.13116633 1.000 1.000 1.000 0.840 ! positive regulation of fat cell differentiation GO:0045600 32 30 1.000 0.13116633 1.000 1.000 1.000 0.663 ! embryonic eye morphogenesis GO:0048048 30 30 1.000 0.13116633 1.000 1.000 1.000 0.848 ! epithelial cell morphogenesis GO:0003382 31 31 1.000 0.13523226 1.000 1.000 1.000 0.782 ! protein deacetylation GO:0006476 31 31 1.000 0.13523226 1.000 1.000 1.000 0.736 ! peptidyl-proline modification GO:0018208 32 31 1.000 0.13523226 1.000 0.13523226 1.000 0.491 ! positive regulation of glial cell differentiation GO:0045687 32 31 1.000 0.13523226 1.000 1.000 1.000 0.816 ! trabecula morphogenesis GO:0061383 31 31 1.000 0.13523226 1.000 1.000 1.000 0.860 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 139 138 2.000 0.13610258 1.000 1.000 1.000 0.952 ! embryonic hindlimb morphogenesis GO:0035116 32 32 1.000 0.13927939 1.000 1.000 1.000 0.821 ! positive regulation of multicellular organism growth GO:0040018 33 32 1.000 0.13927939 1.000 1.000 1.000 0.849 ! negative regulation of cell-cell adhesion GO:0022408 34 33 1.000 0.1433078 1.000 1.000 1.000 0.861 ! embryonic digestive tract development GO:0048566 33 33 1.000 0.1433078 1.000 1.000 1.000 0.866 ! negative regulation of smooth muscle cell proliferation GO:0048662 33 33 1.000 0.1433078 1.000 1.000 1.000 0.824 ! transcription from RNA polymerase II promoter GO:0006366 145 143 2.000 0.14408008 1.000 1.000 1.000 0.925 ! regulation of myeloid cell differentiation GO:0045637 145 144 2.000 0.14568746 1.000 0.49186266 1.000 0.983 ! cell fate determination GO:0001709 34 34 1.000 0.14731757 1.000 1.000 1.000 0.861 ! regulation of gastrulation GO:0010470 35 34 1.000 0.14731757 1.000 1.000 1.000 0.876 ! embryonic camera-type eye development GO:0031076 34 34 1.000 0.14731757 1.000 1.000 1.000 0.863 ! developmental induction GO:0031128 34 34 1.000 0.14731757 1.000 1.000 1.000 0.864 ! cellular response to nutrient GO:0031670 34 34 1.000 0.14731757 1.000 1.000 1.000 0.843 ! protein deacylation GO:0035601 34 34 1.000 0.14731757 1.000 1.000 1.000 0.760 ! regulation of lipid kinase activity GO:0043550 34 34 1.000 0.14731757 1.000 1.000 1.000 0.821 ! bone remodeling GO:0046849 34 34 1.000 0.14731757 1.000 0.14731757 1.000 0.773 ! cellular response to estrogen stimulus GO:0071391 34 34 1.000 0.14731757 1.000 0.14731757 1.000 0.266 ! negative regulation of chromosome organization GO:2001251 34 34 1.000 0.14731757 1.000 1.000 1.000 0.863 ! collagen fibril organization GO:0030199 35 35 1.000 0.15130879 1.000 0.15130879 1.000 0.763 ! negative regulation of BMP signaling pathway GO:0030514 35 35 1.000 0.15130879 1.000 0.15130879 1.000 0.750 ! cellular response to UV GO:0034644 36 35 1.000 0.15130879 1.000 0.15130879 1.000 0.807 ! cell-cell signaling involved in cell fate commitment GO:0045168 35 35 1.000 0.15130879 1.000 1.000 1.000 0.868 ! kidney morphogenesis GO:0060993 35 35 1.000 0.15130879 1.000 1.000 1.000 0.883 ! extracellular matrix organization GO:0030198 151 149 2.000 0.15377991 1.000 0.50371583 1.000 0.931 ! regulation of circadian rhythm GO:0042752 36 36 1.000 0.15528154 1.000 1.000 1.000 0.820 ! regulation of insulin receptor signaling pathway GO:0046626 36 36 1.000 0.15528154 1.000 1.000 1.000 0.829 ! kidney epithelium development GO:0072073 36 36 1.000 0.15528154 1.000 1.000 1.000 0.890 ! extracellular structure organization GO:0043062 152 150 2.000 0.15540904 1.000 0.50605346 1.000 0.932 ! regulation of cell cycle arrest GO:0071156 158 151 2.000 0.15704155 1.000 0.5083802 1.000 0.953 ! peptidyl-threonine phosphorylation GO:0018107 38 37 1.000 0.15923592 1.000 1.000 1.000 0.804 ! sperm motility GO:0030317 39 37 1.000 0.15923592 1.000 0.15923592 1.000 0.543 ! regulation of response to extracellular stimulus GO:0032104 38 37 1.000 0.15923592 1.000 0.15923592 1.000 0.833 GO:0032107|regulation of response to nutrient levels, ! regulation of response to nutrient levels GO:0032107 38 37 1.000 0.15923592 1.000 0.15923592 1.000 0.833 GO:0032104|regulation of response to extracellular stimulus, ! spindle assembly GO:0051225 38 37 1.000 0.15923592 1.000 0.15923592 1.000 0.684 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO:0090092 155 154 2.000 0.16195875 1.000 0.51529564 1.000 0.977 ! embryo implantation GO:0007566 38 38 1.000 0.16317199 1.000 0.16317199 1.000 0.472 ! pituitary gland development GO:0021983 38 38 1.000 0.16317199 1.000 1.000 1.000 0.871 ! cellular response to light stimulus GO:0071482 39 38 1.000 0.16317199 1.000 0.16317199 1.000 0.817 ! regulation of nucleocytoplasmic transport GO:0046822 157 155 2.000 0.16360416 1.000 0.51757935 1.000 0.994 ! mitotic sister chromatid segregation GO:0000070 41 39 1.000 0.16708986 1.000 0.16708986 1.000 0.734 ! G2/M transition of mitotic cell cycle GO:0000086 40 39 1.000 0.16708986 1.000 1.000 1.000 0.760 ! G2/M transition checkpoint GO:0031576 43 39 1.000 0.16708986 1.000 1.000 1.000 0.722 ! regulation of blood vessel endothelial cell migration GO:0043535 40 39 1.000 0.16708986 1.000 1.000 1.000 0.858 ! detection of stimulus GO:0051606 162 158 2.000 0.16855851 1.000 0.52436687 1.000 0.962 ! peptidyl-threonine modification GO:0018210 41 40 1.000 0.17098959 1.000 1.000 1.000 0.813 ! cranial nerve development GO:0021545 40 40 1.000 0.17098959 1.000 1.000 1.000 0.862 ! negative regulation of protein import into nucleus GO:0042308 41 40 1.000 0.17098959 1.000 0.17098959 1.000 0.835 ! apoptotic signaling pathway GO:0097190 41 40 1.000 0.17098959 1.000 1.000 1.000 0.809 ! protein autophosphorylation GO:0046777 161 160 2.000 0.17187588 1.000 0.52883935 1.000 0.948 ! nucleotide-excision repair GO:0006289 42 41 1.000 0.17487127 1.000 1.000 1.000 0.755 ! regulation of interleukin-8 production GO:0032677 43 41 1.000 0.17487127 1.000 1.000 1.000 0.879 ! phosphatidylinositol-mediated signaling GO:0048015 43 41 1.000 0.17487127 1.000 1.000 1.000 0.818 ! lung development GO:0030324 164 164 2.000 0.17854315 1.000 1.000 1.000 0.976 ! inositol lipid-mediated signaling GO:0048017 44 42 1.000 0.17873499 1.000 1.000 1.000 0.819 ! positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 166 165 2.000 0.18021639 1.000 0.53983952 1.000 0.991 ! respiratory tube development GO:0030323 166 166 2.000 0.18189208 1.000 1.000 1.000 0.975 ! Golgi organization GO:0007030 43 43 1.000 0.18258083 1.000 1.000 1.000 0.591 ! positive regulation of gliogenesis GO:0014015 44 43 1.000 0.18258083 1.000 1.000 1.000 0.856 ! smooth muscle cell differentiation GO:0051145 43 43 1.000 0.18258083 1.000 1.000 1.000 0.870 ! pyrimidine-containing compound metabolic process GO:0072527 43 43 1.000 0.18258083 1.000 1.000 1.000 0.861 ! regulation of cellular response to insulin stimulus GO:1900076 45 43 1.000 0.18258083 1.000 1.000 1.000 0.850 ! nucleocytoplasmic transport GO:0006913 170 168 2.000 0.18525059 1.000 0.18525059 1.000 0.929 ! regulation of intracellular protein transport GO:0033157 172 168 2.000 0.18525059 1.000 0.54631738 1.000 0.994 ! positive regulation of growth GO:0045927 172 168 2.000 0.18525059 1.000 0.54631738 1.000 0.972 ! epithelial to mesenchymal transition GO:0001837 44 44 1.000 0.18640886 1.000 0.18640886 1.000 0.880 ! immunoglobulin production GO:0002377 44 44 1.000 0.18640886 1.000 1.000 1.000 0.845 ! positive regulation of myeloid leukocyte differentiation GO:0002763 44 44 1.000 0.18640886 1.000 1.000 1.000 0.877 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 45 44 1.000 0.18640886 1.000 1.000 1.000 0.818 ! intracellular steroid hormone receptor signaling pathway GO:0030518 44 44 1.000 0.18640886 1.000 0.18640886 1.000 0.782 ! regulation of viral genome replication GO:0045069 45 44 1.000 0.18640886 1.000 1.000 1.000 0.760 ! purine ribonucleoside metabolic process GO:0046128 45 44 1.000 0.18640886 1.000 1.000 1.000 0.837 ! cellular aromatic compound metabolic process GO:0006725 171 170 2.000 0.1886182 1.000 1.000 1.000 0.988 ! branching involved in ureteric bud morphogenesis GO:0001658 45 45 1.000 0.19021918 1.000 1.000 1.000 0.877 ! insulin receptor signaling pathway GO:0008286 45 45 1.000 0.19021918 1.000 0.19021918 1.000 0.801 ! ribonucleoside triphosphate biosynthetic process GO:0009201 45 45 1.000 0.19021918 1.000 1.000 1.000 0.837 ! body morphogenesis GO:0010171 47 45 1.000 0.19021918 1.000 0.19021918 1.000 0.825 ! lung alveolus development GO:0048286 45 45 1.000 0.19021918 1.000 1.000 1.000 0.864 ! negative regulation of muscle cell differentiation GO:0051148 45 45 1.000 0.19021918 1.000 0.19021918 1.000 0.736 ! positive regulation of muscle cell differentiation GO:0051149 45 45 1.000 0.19021918 1.000 0.19021918 1.000 0.868 ! nuclear transport GO:0051169 174 172 2.000 0.19199446 1.000 0.19199446 1.000 0.930 ! body fluid secretion GO:0007589 46 46 1.000 0.19401186 1.000 1.000 1.000 0.863 ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:0042787 46 46 1.000 0.19401186 1.000 0.19401186 1.000 0.266 ! regulation of osteoclast differentiation GO:0045670 48 47 1.000 0.19778698 1.000 0.19778698 1.000 0.824 ! negative regulation of nucleocytoplasmic transport GO:0046823 48 47 1.000 0.19778698 1.000 0.19778698 1.000 0.853 ! nucleoside triphosphate biosynthetic process GO:0009142 48 48 1.000 0.20154462 1.000 1.000 1.000 0.848 ! purine nucleoside metabolic process GO:0042278 50 48 1.000 0.20154462 1.000 1.000 1.000 0.828 ! regulation of skeletal muscle fiber development GO:0048742 48 48 1.000 0.20154462 1.000 0.20154462 1.000 0.867 ! centrosome organization GO:0051297 49 48 1.000 0.20154462 1.000 0.20154462 1.000 0.658 ! positive regulation of protein transport GO:0051222 188 182 2.000 0.20899019 1.000 0.5753753 1.000 0.994 ! regulation of chemokine production GO:0032642 50 50 1.000 0.20900779 1.000 1.000 1.000 0.894 ! ureteric bud morphogenesis GO:0060675 50 50 1.000 0.20900779 1.000 1.000 1.000 0.886 ! response to light stimulus GO:0009416 187 183 2.000 0.21069898 1.000 0.57737901 1.000 0.975 ! production of molecular mediator of immune response GO:0002440 51 51 1.000 0.21271348 1.000 1.000 1.000 0.865 ! outflow tract morphogenesis GO:0003151 51 51 1.000 0.21271348 1.000 0.21271348 1.000 0.901 ! transcription initiation, DNA-dependent GO:0006352 51 51 1.000 0.21271348 1.000 1.000 1.000 0.643 ! negative regulation of transmembrane transport GO:0034763 52 51 1.000 0.21271348 1.000 0.21271348 1.000 0.873 ! regulation of response to cytokine stimulus GO:0060759 52 51 1.000 0.21271348 1.000 1.000 1.000 0.882 ! cell aging GO:0007569 52 52 1.000 0.21640201 1.000 0.21640201 1.000 0.854 ! microtubule organizing center organization GO:0031023 53 52 1.000 0.21640201 1.000 0.21640201 1.000 0.700 ! positive regulation of lipid biosynthetic process GO:0046889 53 52 1.000 0.21640201 1.000 1.000 1.000 0.895 ! regulation of binding GO:0051098 188 187 2.000 0.21754834 1.000 1.000 1.000 0.991 ! regulation of generation of precursor metabolites and energy GO:0043467 53 53 1.000 0.22007346 1.000 1.000 1.000 0.874 ! positive regulation of DNA replication GO:0045740 53 53 1.000 0.22007346 1.000 0.22007346 1.000 0.881 ! regulation of G1/S transition of mitotic cell cycle GO:2000045 53 53 1.000 0.22007346 1.000 0.22007346 1.000 0.839 ! heart morphogenesis GO:0003007 190 189 2.000 0.22098085 1.000 0.58920655 1.000 0.998 ! respiratory system development GO:0060541 190 190 2.000 0.22269888 1.000 1.000 1.000 0.975 ! regulation of phosphatidylinositol 3-kinase cascade GO:0014066 54 54 1.000 0.2237279 1.000 1.000 1.000 0.886 ! regulation of glial cell differentiation GO:0045685 55 54 1.000 0.2237279 1.000 1.000 1.000 0.879 ! negative regulation of intracellular protein transport GO:0090317 55 54 1.000 0.2237279 1.000 0.2237279 1.000 0.870 ! positive regulation of cytokine production GO:0001819 194 193 2.000 0.22785956 1.000 0.5969092 1.000 0.995 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 59 56 1.000 0.2309861 1.000 1.000 1.000 0.839 ! nephron development GO:0072006 56 56 1.000 0.2309861 1.000 1.000 1.000 0.897 ! regulation of protein complex assembly GO:0043254 203 196 2.000 0.23302911 1.000 1.000 1.000 0.975 ! metanephros development GO:0001656 57 57 1.000 0.23459 1.000 1.000 1.000 0.898 ! negative regulation of reproductive process GO:2000242 58 58 1.000 0.2381772 1.000 1.000 1.000 0.871 ! lymphocyte activation involved in immune response GO:0002285 59 59 1.000 0.2417478 1.000 1.000 1.000 0.892 ! negative regulation of angiogenesis GO:0016525 60 59 1.000 0.2417478 1.000 1.000 1.000 0.829 ! odontogenesis of dentin-containing tooth GO:0042475 59 59 1.000 0.2417478 1.000 1.000 1.000 0.875 ! regulation of neural precursor cell proliferation GO:2000177 59 59 1.000 0.2417478 1.000 1.000 1.000 0.891 ! viral reproductive process GO:0022415 61 60 1.000 0.24530184 1.000 1.000 1.000 0.857 ! negative regulation of intracellular transport GO:0032387 62 60 1.000 0.24530184 1.000 0.24530184 1.000 0.881 ! induction of apoptosis by intracellular signals GO:0008629 62 61 1.000 0.24883943 1.000 1.000 1.000 0.846 ! nerve development GO:0021675 61 61 1.000 0.24883943 1.000 1.000 1.000 0.889 ! endoderm development GO:0007492 62 62 1.000 0.25236062 1.000 1.000 1.000 0.881 ! diencephalon development GO:0021536 62 62 1.000 0.25236062 1.000 1.000 1.000 0.894 ! positive regulation of proteolysis GO:0045862 63 63 1.000 0.2558655 1.000 1.000 1.000 0.861 ! regulation of skeletal muscle tissue development GO:0048641 63 63 1.000 0.2558655 1.000 0.2558655 1.000 0.887 ! positive regulation of protein import into nucleus GO:0042307 65 64 1.000 0.25935414 1.000 1.000 1.000 0.895 ! mitotic cell cycle checkpoint GO:0007093 67 66 1.000 0.26628299 1.000 1.000 1.000 0.849 ! circadian rhythm GO:0007623 66 66 1.000 0.26628299 1.000 0.26628299 1.000 0.838 ! regulation of BMP signaling pathway GO:0030510 66 66 1.000 0.26628299 1.000 0.26628299 1.000 0.871 ! regulation of fibroblast proliferation GO:0048145 66 66 1.000 0.26628299 1.000 0.26628299 1.000 0.886 ! keratinocyte differentiation GO:0030216 67 67 1.000 0.26972335 1.000 1.000 1.000 0.684 ! regulation of fat cell differentiation GO:0045598 69 67 1.000 0.26972335 1.000 1.000 1.000 0.861 ! ureteric bud development GO:0001657 68 68 1.000 0.27314776 1.000 1.000 1.000 0.899 ! negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 70 69 1.000 0.27655631 1.000 1.000 1.000 0.875 ! positive regulation of myeloid cell differentiation GO:0045639 69 69 1.000 0.27655631 1.000 1.000 1.000 0.895 ! immunoglobulin mediated immune response GO:0016064 70 70 1.000 0.27994905 1.000 1.000 1.000 0.869 ! regulation of endothelial cell migration GO:0010594 72 71 1.000 0.28332607 1.000 1.000 1.000 0.894 ! positive regulation of Wnt receptor signaling pathway GO:0030177 72 71 1.000 0.28332607 1.000 1.000 1.000 0.877 ! myeloid leukocyte differentiation GO:0002573 72 72 1.000 0.28668743 1.000 0.28668743 1.000 0.879 ! B cell mediated immunity GO:0019724 72 72 1.000 0.28668743 1.000 1.000 1.000 0.870 ! positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO:0090100 72 72 1.000 0.28668743 1.000 1.000 1.000 0.896 ! ribonucleotide biosynthetic process GO:0009260 73 73 1.000 0.29003321 1.000 1.000 1.000 0.888 ! regulation of gliogenesis GO:0014013 74 73 1.000 0.29003321 1.000 1.000 1.000 0.893 ! skeletal muscle cell differentiation GO:0035914 73 73 1.000 0.29003321 1.000 0.29003321 1.000 0.823 ! negative regulation of MAPK cascade GO:0043409 73 73 1.000 0.29003321 1.000 1.000 1.000 0.866 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 75 74 1.000 0.29336348 1.000 0.29336348 1.000 0.862 ! odontogenesis GO:0042476 74 74 1.000 0.29336348 1.000 1.000 1.000 0.889 ! signal transduction in response to DNA damage GO:0042770 75 74 1.000 0.29336348 1.000 1.000 1.000 0.875 ! negative regulation of cysteine-type endopeptidase activity GO:2000117 75 74 1.000 0.29336348 1.000 1.000 1.000 0.880 ! hair follicle development GO:0001942 76 76 1.000 0.29997777 1.000 1.000 1.000 0.886 GO:0022405|hair cycle process, GO:0022404|molting cycle process, ! molting cycle process GO:0022404 76 76 1.000 0.29997777 1.000 1.000 1.000 0.886 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! hair cycle process GO:0022405 76 76 1.000 0.29997777 1.000 1.000 1.000 0.886 GO:0022404|molting cycle process, GO:0001942|hair follicle development, ! regulation of cell-cell adhesion GO:0022407 79 76 1.000 0.29997777 1.000 1.000 1.000 0.900 ! developmental growth involved in morphogenesis GO:0060560 76 76 1.000 0.29997777 1.000 1.000 1.000 0.899 ! negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO:0090101 76 76 1.000 0.29997777 1.000 0.29997777 1.000 0.852 ! positive regulation of transmembrane transport GO:0034764 78 77 1.000 0.30326193 1.000 1.000 1.000 0.900 ! vasculogenesis GO:0001570 79 78 1.000 0.30653086 1.000 1.000 1.000 0.896 ! receptor-mediated endocytosis GO:0006898 79 78 1.000 0.30653086 1.000 1.000 1.000 0.873 ! epithelial cell development GO:0002064 79 79 1.000 0.30978463 1.000 1.000 1.000 0.886 ! molting cycle GO:0042303 80 80 1.000 0.31302331 1.000 1.000 1.000 0.882 GO:0042633|hair cycle, ! hair cycle GO:0042633 80 80 1.000 0.31302331 1.000 1.000 1.000 0.882 GO:0042303|molting cycle, ! positive regulation of neuron differentiation GO:0045666 81 80 1.000 0.31302331 1.000 1.000 1.000 0.880 ! establishment of organelle localization GO:0051656 86 80 1.000 0.31302331 1.000 0.31302331 1.000 0.891 ! negative regulation of canonical Wnt receptor signaling pathway GO:0090090 83 80 1.000 0.31302331 1.000 1.000 1.000 0.881 ! viral reproduction GO:0016032 83 81 1.000 0.31624697 1.000 1.000 1.000 0.765 ! regulation of glucose metabolic process GO:0010906 82 82 1.000 0.31945567 1.000 1.000 1.000 0.899 ! regulation of embryonic development GO:0045995 84 83 1.000 0.3226495 1.000 1.000 1.000 0.902 ! positive regulation of protein catabolic process GO:0045732 85 84 1.000 0.3258285 1.000 0.3258285 1.000 0.875 ! regulation of multicellular organism growth GO:0040014 86 85 1.000 0.32899276 1.000 1.000 1.000 0.894 ! cellular response to oxidative stress GO:0034599 87 86 1.000 0.33214235 1.000 1.000 1.000 0.892 ! regulation of striated muscle cell differentiation GO:0051153 86 86 1.000 0.33214235 1.000 0.33214235 1.000 0.888 ! embryonic placenta development GO:0001892 87 87 1.000 0.33527731 1.000 1.000 1.000 0.885 ! regulation of cell size GO:0008361 91 87 1.000 0.33527731 1.000 1.000 1.000 0.885 ! protein processing GO:0016485 87 87 1.000 0.33527731 1.000 1.000 1.000 0.789 ! cholesterol metabolic process GO:0008203 88 88 1.000 0.33839774 1.000 1.000 1.000 0.975 ! regulation of cytokine biosynthetic process GO:0042035 88 88 1.000 0.33839774 1.000 1.000 1.000 0.898 ! positive regulation of hormone secretion GO:0046887 89 88 1.000 0.33839774 1.000 1.000 1.000 0.901 ! lymphocyte mediated immunity GO:0002449 89 89 1.000 0.34150368 1.000 1.000 1.000 0.890 ! regulation of protein kinase B signaling cascade GO:0051896 89 89 1.000 0.34150368 1.000 1.000 1.000 0.900 ! negative regulation of cell adhesion GO:0007162 91 90 1.000 0.34459521 1.000 1.000 1.000 0.894 ! tissue remodeling GO:0048771 91 91 1.000 0.3476724 1.000 0.3476724 1.000 0.897 ! mesenchymal cell development GO:0014031 92 92 1.000 0.3507353 1.000 0.3507353 1.000 0.903 ! digestive tract development GO:0048565 92 92 1.000 0.3507353 1.000 1.000 1.000 0.902 ! camera-type eye morphogenesis GO:0048593 92 92 1.000 0.3507353 1.000 1.000 1.000 0.985 ! tissue homeostasis GO:0001894 93 93 1.000 0.353784 1.000 0.353784 1.000 0.977 ! regulation of smooth muscle cell proliferation GO:0048660 94 94 1.000 0.35681854 1.000 1.000 1.000 0.902 ! cell activation involved in immune response GO:0002263 96 95 1.000 0.35983899 1.000 1.000 1.000 0.903 GO:0002366|leukocyte activation involved in immune response, ! leukocyte activation involved in immune response GO:0002366 96 95 1.000 0.35983899 1.000 1.000 1.000 0.903 GO:0002263|cell activation involved in immune response, ! sterol metabolic process GO:0016125 95 95 1.000 0.35983899 1.000 1.000 1.000 0.964 ! intracellular receptor mediated signaling pathway GO:0030522 95 95 1.000 0.35983899 1.000 0.35983899 1.000 0.971 ! regulation of DNA replication GO:0006275 98 96 1.000 0.36284543 1.000 0.36284543 1.000 0.978 ! response to estrogen stimulus GO:0043627 96 96 1.000 0.36284543 1.000 0.36284543 1.000 0.925 ! protein maturation GO:0051604 96 96 1.000 0.36284543 1.000 1.000 1.000 0.925 ! regulation of cell shape GO:0008360 100 97 1.000 0.36583791 1.000 0.36583791 1.000 0.762 ! negative regulation of protein transport GO:0051224 100 97 1.000 0.36583791 1.000 0.36583791 1.000 0.986 ! regulation of lipid biosynthetic process GO:0046890 101 100 1.000 0.37473225 1.000 1.000 1.000 0.903 ! organelle assembly GO:0070925 102 100 1.000 0.37473225 1.000 0.37473225 1.000 0.932 ! cellular response to nutrient levels GO:0031669 102 101 1.000 0.37766954 1.000 1.000 1.000 0.966 ! digestive system development GO:0055123 101 101 1.000 0.37766954 1.000 1.000 1.000 0.902 ! regulation of cellular carbohydrate metabolic process GO:0010675 104 102 1.000 0.3805932 1.000 1.000 1.000 0.903 ! positive regulation of lipid metabolic process GO:0045834 103 102 1.000 0.3805932 1.000 1.000 1.000 0.904 ! cellular response to steroid hormone stimulus GO:0071383 105 104 1.000 0.38639984 1.000 0.38639984 1.000 0.939 ! glial cell differentiation GO:0010001 108 105 1.000 0.38928295 1.000 1.000 1.000 0.992 ! mesenchymal cell differentiation GO:0048762 106 105 1.000 0.38928295 1.000 0.38928295 1.000 0.904 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 106 106 1.000 0.39215267 1.000 1.000 1.000 0.982 ! regulation of carbohydrate metabolic process GO:0006109 109 107 1.000 0.39500907 1.000 1.000 1.000 0.998 ! positive regulation of cell growth GO:0030307 110 107 1.000 0.39500907 1.000 0.39500907 1.000 0.950 ! endocrine system development GO:0035270 107 107 1.000 0.39500907 1.000 1.000 1.000 0.995 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 108 107 1.000 0.39500907 1.000 0.39500907 1.000 0.784 ! mammary gland development GO:0030879 108 108 1.000 0.3978522 1.000 1.000 1.000 0.996 ! regulation of muscle cell differentiation GO:0051147 108 108 1.000 0.3978522 1.000 0.3978522 1.000 0.975 ! post-embryonic development GO:0009791 111 109 1.000 0.40068212 1.000 1.000 1.000 0.959 ! positive regulation of DNA metabolic process GO:0051054 111 109 1.000 0.40068212 1.000 0.40068212 1.000 0.997 ! proteasomal protein catabolic process GO:0010498 111 110 1.000 0.40349889 1.000 0.40349889 1.000 0.792 ! retina development in camera-type eye GO:0060041 110 110 1.000 0.40349889 1.000 0.40349889 1.000 0.945 ! negative regulation of cytokine production GO:0001818 114 111 1.000 0.40630258 1.000 1.000 1.000 1.00 ! cardiac chamber morphogenesis GO:0003206 112 112 1.000 0.40909324 1.000 1.000 1.000 0.999 ! protein glycosylation GO:0006486 113 112 1.000 0.40909324 1.000 1.000 1.000 0.798 GO:0043413|macromolecule glycosylation, ! hindbrain development GO:0030902 114 112 1.000 0.40909324 1.000 1.000 1.000 0.987 ! macromolecule glycosylation GO:0043413 113 112 1.000 0.40909324 1.000 1.000 1.000 0.798 GO:0006486|protein glycosylation, ! leukocyte mediated immunity GO:0002443 114 113 1.000 0.41187094 1.000 1.000 1.000 0.984 ! negative regulation of Wnt receptor signaling pathway GO:0030178 117 113 1.000 0.41187094 1.000 1.000 1.000 0.956 ! negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433 117 113 1.000 0.41187094 1.000 1.000 1.000 0.978 ! cellular response to amino acid stimulus GO:0071230 117 113 1.000 0.41187094 1.000 1.000 1.000 0.176 ! B cell activation GO:0042113 114 114 1.000 0.41463573 1.000 1.000 1.000 0.956 ! negative regulation of neuron apoptosis GO:0043524 115 114 1.000 0.41463573 1.000 1.000 1.000 0.996 ! adaptive immune response GO:0002250 115 115 1.000 0.41738768 1.000 1.000 1.000 0.985 ! regulation of striated muscle tissue development GO:0016202 115 115 1.000 0.41738768 1.000 0.41738768 1.000 0.997 ! regulation of muscle organ development GO:0048634 116 116 1.000 0.42012683 1.000 0.42012683 1.000 0.997 ! ear morphogenesis GO:0042471 119 118 1.000 0.42556702 1.000 1.000 1.000 0.971 ! embryonic skeletal system development GO:0048706 118 118 1.000 0.42556702 1.000 1.000 1.000 0.952 ! cellular response to acid GO:0071229 123 119 1.000 0.42826816 1.000 1.000 1.000 0.270 ! negative regulation of intracellular protein kinase cascade GO:0010741 120 120 1.000 0.43095675 1.000 1.000 1.000 0.977 ! response to amino acid stimulus GO:0043200 124 120 1.000 0.43095675 1.000 1.000 1.000 0.327 ! glycosylation GO:0070085 121 120 1.000 0.43095675 1.000 1.000 1.000 0.916 ! cellular response to amine stimulus GO:0071418 125 121 1.000 0.43363285 1.000 1.000 1.000 0.378 ! protein folding GO:0006457 124 122 1.000 0.4362965 1.000 0.4362965 1.000 0.726 ! cellular response to organic nitrogen GO:0071417 126 122 1.000 0.4362965 1.000 1.000 1.000 0.404 ! regulation of muscle system process GO:0090257 122 122 1.000 0.4362965 1.000 1.000 1.000 0.999 ! gastrulation GO:0007369 125 123 1.000 0.43894777 1.000 0.43894777 1.000 0.987 ! cellular response to extracellular stimulus GO:0031668 124 123 1.000 0.43894777 1.000 1.000 1.000 0.964 ! regulation of ERK1 and ERK2 cascade GO:0070372 125 123 1.000 0.43894777 1.000 1.000 1.000 0.998 ! gliogenesis GO:0042063 127 124 1.000 0.44158672 1.000 1.000 1.000 0.991 ! visual perception GO:0007601 128 128 1.000 0.45202038 1.000 0.45202038 1.000 0.916 ! eye morphogenesis GO:0048592 128 128 1.000 0.45202038 1.000 1.000 1.000 0.973 ! interphase of mitotic cell cycle GO:0051329 131 128 1.000 0.45202038 1.000 1.000 1.000 0.948 ! negative regulation of cell migration GO:0030336 131 129 1.000 0.45459854 1.000 1.000 1.000 0.978 ! sensory perception of light stimulus GO:0050953 129 129 1.000 0.45459854 1.000 0.45459854 1.000 0.916 ! mesenchyme development GO:0060485 130 129 1.000 0.45459854 1.000 0.45459854 1.000 1.00 ! multicellular organismal homeostasis GO:0048871 132 132 1.000 0.46226131 1.000 0.46226131 1.000 0.983 ! interphase GO:0051325 135 132 1.000 0.46226131 1.000 1.000 1.000 0.946 ! negative regulation of cell motility GO:2000146 134 132 1.000 0.46226131 1.000 1.000 1.000 0.979 ! protein dephosphorylation GO:0006470 135 134 1.000 0.46731061 1.000 0.46731061 1.000 0.688 ! cellular response to external stimulus GO:0071496 137 136 1.000 0.47231305 1.000 1.000 1.000 0.964 ! negative regulation of cellular component movement GO:0051271 139 137 1.000 0.47479682 1.000 1.000 1.000 0.978 ! response to acid GO:0001101 145 138 1.000 0.47726904 1.000 1.000 1.000 0.550 ! positive regulation of catabolic process GO:0009896 141 139 1.000 0.47972976 1.000 0.47972976 1.000 0.978 ! negative regulation of cell growth GO:0030308 141 141 1.000 0.4846169 1.000 1.000 1.000 0.951 ! response to amine stimulus GO:0014075 146 142 1.000 0.48704343 1.000 1.000 1.000 0.669 ! organelle localization GO:0051640 150 142 1.000 0.48704343 1.000 0.48704343 1.000 0.979 ! glycoprotein biosynthetic process GO:0009101 149 148 1.000 0.50136726 1.000 1.000 1.000 0.923 ! negative regulation of locomotion GO:0040013 150 148 1.000 0.50136726 1.000 1.000 1.000 0.983 ! sulfur compound metabolic process GO:0006790 150 149 1.000 0.50371583 1.000 1.000 1.000 0.961 ! axon guidance GO:0007411 151 149 1.000 0.50371583 1.000 0.50371583 1.000 0.959 ! negative regulation of protein modification process GO:0031400 152 149 1.000 0.50371583 1.000 1.000 1.000 0.993 ! nucleotide biosynthetic process GO:0009165 151 150 1.000 0.50605346 1.000 1.000 1.000 0.977 ! branching morphogenesis of a tube GO:0048754 150 150 1.000 0.50605346 1.000 1.000 1.000 0.999 ! response to organic nitrogen GO:0010243 156 152 1.000 0.51069612 1.000 1.000 1.000 0.733 ! morphogenesis of a branching epithelium GO:0061138 153 153 1.000 0.51300124 1.000 1.000 1.000 0.999 ! negative regulation of organelle organization GO:0010639 162 154 1.000 0.51529564 1.000 1.000 1.000 0.982 ! kidney development GO:0001822 160 158 1.000 0.52436687 1.000 1.000 1.000 0.991 ! negative regulation of endopeptidase activity GO:0010951 159 158 1.000 0.52436687 1.000 1.000 1.000 0.802 ! nucleobase-containing compound biosynthetic process GO:0034654 161 160 1.000 0.52883935 1.000 1.000 1.000 0.980 ! skeletal muscle tissue development GO:0007519 162 161 1.000 0.53105998 1.000 0.53105998 1.000 0.947 ! regulation of protein catabolic process GO:0042176 167 165 1.000 0.53983952 1.000 0.53983952 1.000 0.956 ! regulation of angiogenesis GO:0045765 166 165 1.000 0.53983952 1.000 1.000 1.000 0.967 ! regulation of hormone secretion GO:0046883 169 168 1.000 0.54631738 1.000 1.000 1.000 0.991 ! skeletal muscle organ development GO:0060538 169 168 1.000 0.54631738 1.000 0.54631738 1.000 0.949 ! regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043281 172 170 1.000 0.55058579 1.000 1.000 1.000 0.979 ! rhythmic process GO:0048511 170 170 1.000 0.55058579 1.000 0.55058579 1.000 0.963 ! renal system development GO:0072001 174 172 1.000 0.55481451 1.000 1.000 1.000 0.991 ! lymphocyte differentiation GO:0030098 175 174 1.000 0.55900389 1.000 1.000 1.000 0.971 ! regulation of neuron apoptosis GO:0043523 177 175 1.000 0.56108395 1.000 1.000 1.000 0.994 ! response to drug GO:0042493 177 177 1.000 0.56521501 1.000 1.000 1.000 0.978 ! regulation of cysteine-type endopeptidase activity GO:2000116 179 177 1.000 0.56521501 1.000 1.000 1.000 0.979 ! regulation of body fluid levels GO:0050878 181 179 1.000 0.56930764 1.000 1.000 1.000 0.961 ! morphogenesis of a branching structure GO:0001763 182 182 1.000 0.5753753 1.000 1.000 1.000 0.998 ! regulation of cellular component size GO:0032535 196 188 1.000 0.58725827 1.000 1.000 1.000 0.956 ! regulation of proteolysis GO:0030162 191 190 1.000 0.59114575 1.000 1.000 1.000 0.916 ! negative regulation of growth GO:0045926 193 193 1.000 0.5969092 1.000 1.000 1.000 0.965 ! mitochondrion organization GO:0007005 204 194 1.000 0.59881246 1.000 1.000 1.000 0.946 ! ear development GO:0043583 195 194 1.000 0.59881246 1.000 1.000 1.000 0.962 ! glycoprotein metabolic process GO:0009100 198 196 1.000 0.60259235 1.000 1.000 1.000 0.928 ! steroid metabolic process GO:0008202 197 197 1.000 0.60446908 1.000 1.000 1.000 0.958 ! dephosphorylation GO:0016311 198 197 1.000 0.60446908 1.000 0.60446908 1.000 0.909 ! response to oxidative stress GO:0006979 200 199 1.000 0.60819629 1.000 1.000 1.000 0.970 ! very long-chain fatty acid metabolic process GO:0000038 45 45 0.000 1.000 1.000 1.000 1.000 0.830 ! transition metal ion transport GO:0000041 69 69 0.000 1.000 1.000 1.000 1.000 0.770 ! autophagic vacuole assembly GO:0000045 25 24 0.000 1.000 1.000 1.000 1.000 0.419 ! protein import into nucleus, translocation GO:0000060 21 21 0.000 1.000 1.000 1.000 1.000 0.741 ! DNA damage checkpoint GO:0000077 77 74 0.000 1.000 1.000 1.000 1.000 0.845 ! regulation of cyclin-dependent protein kinase activity GO:0000079 64 62 0.000 1.000 1.000 1.000 1.000 0.789 ! G1/S transition of mitotic cell cycle GO:0000082 66 64 0.000 1.000 1.000 1.000 1.000 0.824 ! sulfur amino acid metabolic process GO:0000096 26 26 0.000 1.000 1.000 1.000 1.000 0.797 ! MAPK cascade GO:0000165 137 137 0.000 1.000 1.000 1.000 1.000 0.971 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 34 32 0.000 1.000 1.000 1.000 1.000 0.260 ! activation of MAPKK activity GO:0000186 34 34 0.000 1.000 1.000 1.000 1.000 0.750 ! activation of MAPK activity GO:0000187 95 95 0.000 1.000 1.000 1.000 1.000 0.983 ! protein polyubiquitination GO:0000209 113 113 0.000 1.000 1.000 1.000 1.000 0.783 ! spliceosome assembly GO:0000245 22 21 0.000 1.000 1.000 1.000 1.000 0.366 ! polysaccharide biosynthetic process GO:0000271 52 52 0.000 1.000 1.000 1.000 1.000 0.853 ! polysaccharide catabolic process GO:0000272 30 30 0.000 1.000 1.000 1.000 1.000 0.786 ! response to reactive oxygen species GO:0000302 92 92 0.000 1.000 1.000 1.000 1.000 0.985 ! RNA splicing, via transesterification reactions GO:0000375 65 64 0.000 1.000 1.000 1.000 1.000 0.531 ! RNA splicing, via transesterification reactions with bulged adenosine as nucleophile GO:0000377 64 63 0.000 1.000 1.000 1.000 1.000 0.544 GO:0000398|nuclear mRNA splicing, via spliceosome, ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 23 22 0.000 1.000 1.000 1.000 1.000 0.248 ! nuclear mRNA splicing, via spliceosome GO:0000398 64 63 0.000 1.000 1.000 1.000 1.000 0.544 GO:0000377|RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, ! embryonic axis specification GO:0000578 29 29 0.000 1.000 1.000 1.000 1.000 0.811 ! syncytium formation by plasma membrane fusion GO:0000768 20 20 0.000 1.000 1.000 1.000 1.000 0.693 ! cytokinesis GO:0000910 68 66 0.000 1.000 1.000 1.000 1.000 0.776 ! nuclear-transcribed mRNA catabolic process GO:0000956 58 55 0.000 1.000 1.000 1.000 1.000 0.644 ! regulation of neurotransmitter levels GO:0001505 84 83 0.000 1.000 1.000 1.000 1.000 0.869 ! regulation of action potential GO:0001508 156 153 0.000 1.000 1.000 1.000 1.000 0.963 ! retinoid metabolic process GO:0001523 40 40 0.000 1.000 1.000 1.000 1.000 0.762 GO:0016101|diterpenoid metabolic process, ! ciliary or flagellar motility GO:0001539 23 21 0.000 1.000 1.000 1.000 1.000 0.207 ! ovarian follicle development GO:0001541 53 53 0.000 1.000 1.000 1.000 1.000 0.856 ! response to protozoan GO:0001562 27 27 0.000 1.000 1.000 1.000 1.000 0.793 ! patterning of blood vessels GO:0001569 40 40 0.000 1.000 1.000 1.000 1.000 0.859 ! microtubule bundle formation GO:0001578 40 33 0.000 1.000 1.000 1.000 1.000 0.616 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 23 23 0.000 1.000 1.000 1.000 1.000 0.0780 ! temperature homeostasis GO:0001659 27 27 0.000 1.000 1.000 1.000 1.000 0.842 ! behavioral fear response GO:0001662 22 22 0.000 1.000 1.000 1.000 1.000 0.715 ! response to hypoxia GO:0001666 131 129 0.000 1.000 1.000 1.000 1.000 0.990 ! ameboidal cell migration GO:0001667 75 75 0.000 1.000 1.000 1.000 1.000 0.891 ! long-chain fatty acid metabolic process GO:0001676 64 64 0.000 1.000 1.000 1.000 1.000 0.865 ! cellular glucose homeostasis GO:0001678 38 38 0.000 1.000 1.000 1.000 1.000 0.759 ! gastrulation with mouth forming second GO:0001702 33 32 0.000 1.000 1.000 1.000 1.000 0.776 ! formation of primary germ layer GO:0001704 78 78 0.000 1.000 1.000 1.000 1.000 0.897 ! endoderm formation GO:0001706 26 26 0.000 1.000 1.000 1.000 1.000 0.793 ! mesoderm formation GO:0001707 57 57 0.000 1.000 1.000 1.000 1.000 0.887 ! cell fate specification GO:0001708 68 67 0.000 1.000 1.000 1.000 1.000 0.884 ! morphogenesis of a polarized epithelium GO:0001738 22 21 0.000 1.000 1.000 1.000 1.000 0.758 ! eye photoreceptor cell differentiation GO:0001754 43 43 0.000 1.000 1.000 1.000 1.000 0.793 ! neural crest cell migration GO:0001755 36 36 0.000 1.000 1.000 1.000 1.000 0.847 ! somitogenesis GO:0001756 56 56 0.000 1.000 1.000 1.000 1.000 0.860 ! organ induction GO:0001759 20 20 0.000 1.000 1.000 1.000 1.000 0.790 ! neuron migration GO:0001764 104 103 0.000 1.000 1.000 1.000 1.000 0.957 ! leukocyte homeostasis GO:0001776 50 49 0.000 1.000 1.000 1.000 1.000 0.870 ! B cell homeostasis GO:0001782 21 21 0.000 1.000 1.000 1.000 1.000 0.740 ! cytokine production GO:0001816 88 87 0.000 1.000 1.000 1.000 1.000 0.892 ! release of cytochrome c from mitochondria GO:0001836 23 23 0.000 1.000 1.000 1.000 1.000 0.791 ! endothelial cell development GO:0001885 24 24 0.000 1.000 1.000 1.000 1.000 0.734 ! cell killing GO:0001906 23 23 0.000 1.000 1.000 1.000 1.000 0.804 ! regulation of leukocyte mediated cytotoxicity GO:0001910 47 47 0.000 1.000 1.000 1.000 1.000 0.879 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 37 37 0.000 1.000 1.000 1.000 1.000 0.867 ! regulation of T cell mediated cytotoxicity GO:0001914 24 24 0.000 1.000 1.000 1.000 1.000 0.848 ! positive regulation of T cell mediated cytotoxicity GO:0001916 21 21 0.000 1.000 1.000 1.000 1.000 0.839 ! regulation of receptor recycling GO:0001919 22 21 0.000 1.000 1.000 1.000 1.000 0.710 ! negative regulation of protein phosphorylation GO:0001933 91 89 0.000 1.000 1.000 1.000 1.000 0.900 ! regulation of endothelial cell proliferation GO:0001936 75 74 0.000 1.000 1.000 1.000 1.000 0.891 ! negative regulation of endothelial cell proliferation GO:0001937 25 24 0.000 1.000 1.000 1.000 1.000 0.776 ! positive regulation of endothelial cell proliferation GO:0001938 52 52 0.000 1.000 1.000 1.000 1.000 0.864 ! heart looping GO:0001947 43 43 0.000 1.000 1.000 1.000 1.000 0.884 ! regulation of cell-matrix adhesion GO:0001952 56 56 0.000 1.000 1.000 1.000 1.000 0.882 ! positive regulation of cell-matrix adhesion GO:0001954 25 25 0.000 1.000 1.000 1.000 1.000 0.816 ! endochondral ossification GO:0001958 22 22 0.000 1.000 1.000 1.000 1.000 0.683 GO:0036075|replacement ossification, ! regulation of cytokine-mediated signaling pathway GO:0001959 46 45 0.000 1.000 1.000 1.000 1.000 0.878 ! negative regulation of cytokine-mediated signaling pathway GO:0001960 22 21 0.000 1.000 1.000 1.000 1.000 0.805 ! startle response GO:0001964 22 22 0.000 1.000 1.000 1.000 1.000 0.804 ! blood vessel remodeling GO:0001974 35 35 0.000 1.000 1.000 1.000 1.000 0.872 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 23 22 0.000 1.000 1.000 1.000 1.000 0.816 ! regulation of systemic arterial blood pressure by hormone GO:0001990 33 33 0.000 1.000 1.000 1.000 1.000 0.847 ! regulation of the force of heart contraction GO:0002026 26 26 0.000 1.000 1.000 1.000 1.000 0.804 ! regulation of heart rate GO:0002027 61 60 0.000 1.000 1.000 1.000 1.000 0.898 ! regulation of sodium ion transport GO:0002028 53 50 0.000 1.000 1.000 1.000 1.000 0.871 ! sprouting angiogenesis GO:0002040 37 37 0.000 1.000 1.000 1.000 1.000 0.841 ! positive regulation of neuroblast proliferation GO:0002052 20 20 0.000 1.000 1.000 1.000 1.000 0.785 ! positive regulation of mesenchymal cell proliferation GO:0002053 37 37 0.000 1.000 1.000 1.000 1.000 0.858 ! chondrocyte differentiation GO:0002062 41 41 0.000 1.000 1.000 1.000 1.000 0.837 ! columnar/cuboidal epithelial cell differentiation GO:0002065 23 23 0.000 1.000 1.000 1.000 1.000 0.707 ! lens development in camera-type eye GO:0002088 56 56 0.000 1.000 1.000 1.000 1.000 0.784 ! lens morphogenesis in camera-type eye GO:0002089 25 25 0.000 1.000 1.000 1.000 1.000 0.739 ! behavioral defense response GO:0002209 23 23 0.000 1.000 1.000 1.000 1.000 0.728 ! activation of innate immune response GO:0002218 51 50 0.000 1.000 1.000 1.000 1.000 0.869 ! pattern recognition receptor signaling pathway GO:0002221 39 39 0.000 1.000 1.000 1.000 1.000 0.846 ! toll-like receptor signaling pathway GO:0002224 27 27 0.000 1.000 1.000 1.000 1.000 0.795 ! hemopoietic progenitor cell differentiation GO:0002244 30 30 0.000 1.000 1.000 1.000 1.000 0.823 ! activation of immune response GO:0002253 152 149 0.000 1.000 1.000 1.000 1.000 0.960 ! lymphocyte homeostasis GO:0002260 45 44 0.000 1.000 1.000 1.000 1.000 0.858 ! myeloid leukocyte activation GO:0002274 81 80 0.000 1.000 1.000 1.000 1.000 0.894 ! myeloid cell activation involved in immune response GO:0002275 35 34 0.000 1.000 1.000 1.000 1.000 0.843 ! T cell activation involved in immune response GO:0002286 30 30 0.000 1.000 1.000 1.000 1.000 0.840 ! immune response-activating cell surface receptor signaling pathway GO:0002429 68 67 0.000 1.000 1.000 1.000 1.000 0.868 ! inflammatory response to antigenic stimulus GO:0002437 21 21 0.000 1.000 1.000 1.000 1.000 0.728 ! myeloid leukocyte mediated immunity GO:0002444 28 27 0.000 1.000 1.000 1.000 1.000 0.825 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 35 35 0.000 1.000 1.000 1.000 1.000 0.664 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0.000 1.000 1.000 1.000 1.000 0.619 ! antigen processing and presentation of exogenous peptide antigen GO:0002478 21 21 0.000 1.000 1.000 1.000 1.000 0.739 ! acute inflammatory response GO:0002526 55 55 0.000 1.000 1.000 1.000 1.000 0.780 ! regulation of immunoglobulin production GO:0002637 40 39 0.000 1.000 1.000 1.000 1.000 0.866 ! regulation of acute inflammatory response GO:0002673 54 53 0.000 1.000 1.000 1.000 1.000 0.900 ! positive regulation of acute inflammatory response GO:0002675 26 26 0.000 1.000 1.000 1.000 1.000 0.881 ! negative regulation of immune system process GO:0002683 199 195 0.000 1.000 1.000 1.000 1.000 0.992 ! regulation of leukocyte migration GO:0002685 91 90 0.000 1.000 1.000 1.000 1.000 0.902 ! positive regulation of leukocyte migration GO:0002687 70 70 0.000 1.000 1.000 1.000 1.000 0.898 ! regulation of leukocyte chemotaxis GO:0002688 58 58 0.000 1.000 1.000 1.000 1.000 0.895 ! positive regulation of leukocyte chemotaxis GO:0002690 50 50 0.000 1.000 1.000 1.000 1.000 0.889 ! negative regulation of leukocyte activation GO:0002695 114 113 0.000 1.000 1.000 1.000 1.000 0.989 ! positive regulation of leukocyte activation GO:0002696 196 194 0.000 1.000 1.000 1.000 1.000 0.999 ! negative regulation of immune effector process GO:0002698 70 70 0.000 1.000 1.000 1.000 1.000 0.901 ! positive regulation of immune effector process GO:0002699 118 118 0.000 1.000 1.000 1.000 1.000 0.904 ! regulation of production of molecular mediator of immune response GO:0002700 69 68 0.000 1.000 1.000 1.000 1.000 0.901 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 25 0.000 1.000 1.000 1.000 1.000 0.849 ! regulation of leukocyte mediated immunity GO:0002703 119 119 0.000 1.000 1.000 1.000 1.000 1.00 ! negative regulation of leukocyte mediated immunity GO:0002704 22 22 0.000 1.000 1.000 1.000 1.000 0.815 GO:0002707|negative regulation of lymphocyte mediated immunity, ! positive regulation of leukocyte mediated immunity GO:0002705 61 61 0.000 1.000 1.000 1.000 1.000 0.900 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of lymphocyte mediated immunity GO:0002706 96 96 0.000 1.000 1.000 1.000 1.000 0.903 ! negative regulation of lymphocyte mediated immunity GO:0002707 22 22 0.000 1.000 1.000 1.000 1.000 0.816 GO:0002704|negative regulation of leukocyte mediated immunity, ! positive regulation of lymphocyte mediated immunity GO:0002708 61 61 0.000 1.000 1.000 1.000 1.000 0.900 GO:0002705|positive regulation of leukocyte mediated immunity, ! regulation of T cell mediated immunity GO:0002709 42 42 0.000 1.000 1.000 1.000 1.000 0.891 ! positive regulation of T cell mediated immunity GO:0002711 33 33 0.000 1.000 1.000 1.000 1.000 0.882 ! regulation of B cell mediated immunity GO:0002712 41 41 0.000 1.000 1.000 1.000 1.000 0.880 GO:0002889|regulation of immunoglobulin mediated immune response, ! regulation of natural killer cell mediated immunity GO:0002715 28 28 0.000 1.000 1.000 1.000 1.000 0.809 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! positive regulation of natural killer cell mediated immunity GO:0002717 21 21 0.000 1.000 1.000 1.000 1.000 0.767 ! regulation of cytokine production involved in immune response GO:0002718 38 38 0.000 1.000 1.000 1.000 1.000 0.887 ! positive regulation of cytokine production involved in immune response GO:0002720 20 20 0.000 1.000 1.000 1.000 1.000 0.837 ! immune response-activating signal transduction GO:0002757 105 104 0.000 1.000 1.000 1.000 1.000 0.984 ! innate immune response-activating signal transduction GO:0002758 42 42 0.000 1.000 1.000 1.000 1.000 0.857 ! negative regulation of myeloid leukocyte differentiation GO:0002762 33 33 0.000 1.000 1.000 1.000 1.000 0.812 ! immune response-regulating signaling pathway GO:0002764 116 115 0.000 1.000 1.000 1.000 1.000 0.989 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 77 76 0.000 1.000 1.000 1.000 1.000 0.884 ! peptide secretion GO:0002790 51 51 0.000 1.000 1.000 1.000 1.000 0.854 ! regulation of peptide secretion GO:0002791 130 129 0.000 1.000 1.000 1.000 1.000 0.984 GO:0090087|regulation of peptide transport, ! negative regulation of peptide secretion GO:0002792 39 39 0.000 1.000 1.000 1.000 1.000 0.833 ! positive regulation of peptide secretion GO:0002793 62 61 0.000 1.000 1.000 1.000 1.000 0.883 ! regulation of adaptive immune response GO:0002819 111 111 0.000 1.000 1.000 1.000 1.000 0.904 ! positive regulation of adaptive immune response GO:0002821 66 66 0.000 1.000 1.000 1.000 1.000 0.903 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 102 102 0.000 1.000 1.000 1.000 1.000 0.904 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 61 0.000 1.000 1.000 1.000 1.000 0.902 ! regulation of T-helper 1 type immune response GO:0002825 21 21 0.000 1.000 1.000 1.000 1.000 0.815 ! regulation of type 2 immune response GO:0002828 23 23 0.000 1.000 1.000 1.000 1.000 0.836 ! regulation of response to biotic stimulus GO:0002831 65 62 0.000 1.000 1.000 1.000 1.000 0.886 ! regulation of inflammatory response to antigenic stimulus GO:0002861 28 27 0.000 1.000 1.000 1.000 1.000 0.852 ! regulation of myeloid leukocyte mediated immunity GO:0002886 30 30 0.000 1.000 1.000 1.000 1.000 0.856 ! regulation of immunoglobulin mediated immune response GO:0002889 41 41 0.000 1.000 1.000 1.000 1.000 0.880 GO:0002712|regulation of B cell mediated immunity, ! regulation of humoral immune response GO:0002920 27 27 0.000 1.000 1.000 1.000 1.000 0.835 ! generation of a signal involved in cell-cell signaling GO:0003001 125 123 0.000 1.000 1.000 1.000 1.000 0.977 GO:0023061|signal release, ! muscle system process GO:0003012 142 142 0.000 1.000 1.000 1.000 1.000 0.983 ! renal system process GO:0003014 62 62 0.000 1.000 1.000 1.000 1.000 0.901 ! heart process GO:0003015 45 45 0.000 1.000 1.000 1.000 1.000 0.852 GO:0060047|heart contraction, ! vascular process in circulatory system GO:0003018 87 87 0.000 1.000 1.000 1.000 1.000 0.903 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 41 41 0.000 1.000 1.000 1.000 1.000 0.876 ! regulation of systemic arterial blood pressure GO:0003073 78 77 0.000 1.000 1.000 1.000 1.000 0.902 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 23 23 0.000 1.000 1.000 1.000 1.000 0.804 ! embryonic heart tube morphogenesis GO:0003143 49 49 0.000 1.000 1.000 1.000 1.000 0.887 ! regulation of organ formation GO:0003156 33 33 0.000 1.000 1.000 1.000 1.000 0.875 ! endothelium development GO:0003158 43 43 0.000 1.000 1.000 1.000 1.000 0.849 ! heart valve development GO:0003170 27 27 0.000 1.000 1.000 1.000 1.000 0.873 ! heart valve morphogenesis GO:0003179 25 25 0.000 1.000 1.000 1.000 1.000 0.867 ! endocardial cushion development GO:0003197 25 25 0.000 1.000 1.000 1.000 1.000 0.873 ! cardiac ventricle morphogenesis GO:0003208 68 68 0.000 1.000 1.000 1.000 1.000 0.900 ! cardiac atrium morphogenesis GO:0003209 24 24 0.000 1.000 1.000 1.000 1.000 0.856 ! ventricular cardiac muscle tissue development GO:0003229 49 49 0.000 1.000 1.000 1.000 1.000 0.880 ! cardiac atrium development GO:0003230 27 27 0.000 1.000 1.000 1.000 1.000 0.866 ! regulation of membrane depolarization GO:0003254 23 23 0.000 1.000 1.000 1.000 1.000 0.812 ! amino acid transmembrane transport GO:0003333 43 43 0.000 1.000 1.000 1.000 1.000 0.613 ! cilium movement GO:0003341 22 21 0.000 1.000 1.000 1.000 1.000 0.415 ! axis elongation GO:0003401 26 26 0.000 1.000 1.000 1.000 1.000 0.844 ! neural retina development GO:0003407 29 29 0.000 1.000 1.000 1.000 1.000 0.732 ! polysaccharide metabolic process GO:0005976 124 123 0.000 1.000 1.000 1.000 1.000 0.958 ! glycogen metabolic process GO:0005977 43 43 0.000 1.000 1.000 1.000 1.000 0.784 ! regulation of glycogen biosynthetic process GO:0005979 27 27 0.000 1.000 1.000 1.000 1.000 0.803 GO:0010962|regulation of glucan biosynthetic process, ! monosaccharide metabolic process GO:0005996 196 195 0.000 1.000 1.000 1.000 1.000 0.968 ! glucose metabolic process GO:0006006 118 117 0.000 1.000 1.000 1.000 1.000 0.977 ! glucose catabolic process GO:0006007 52 52 0.000 1.000 1.000 1.000 1.000 0.847 ! aminoglycan metabolic process GO:0006022 73 72 0.000 1.000 1.000 1.000 1.000 0.854 ! aminoglycan biosynthetic process GO:0006023 29 29 0.000 1.000 1.000 1.000 1.000 0.793 ! glycosaminoglycan biosynthetic process GO:0006024 27 27 0.000 1.000 1.000 1.000 1.000 0.780 ! aminoglycan catabolic process GO:0006026 22 22 0.000 1.000 1.000 1.000 1.000 0.701 ! proteoglycan metabolic process GO:0006029 51 50 0.000 1.000 1.000 1.000 1.000 0.820 ! amino sugar metabolic process GO:0006040 29 29 0.000 1.000 1.000 1.000 1.000 0.725 ! glucosamine metabolic process GO:0006041 20 20 0.000 1.000 1.000 1.000 1.000 0.680 GO:0006044|N-acetylglucosamine metabolic process, ! N-acetylglucosamine metabolic process GO:0006044 20 20 0.000 1.000 1.000 1.000 1.000 0.680 GO:0006041|glucosamine metabolic process, ! glycerol metabolic process GO:0006071 25 25 0.000 1.000 1.000 1.000 1.000 0.594 ! cellular glucan metabolic process GO:0006073 44 44 0.000 1.000 1.000 1.000 1.000 0.791 GO:0044042|glucan metabolic process, ! cellular aldehyde metabolic process GO:0006081 33 33 0.000 1.000 1.000 1.000 1.000 0.821 ! acetyl-CoA metabolic process GO:0006084 44 44 0.000 1.000 1.000 1.000 1.000 0.841 ! pyruvate metabolic process GO:0006090 22 20 0.000 1.000 1.000 1.000 1.000 0.762 ! gluconeogenesis GO:0006094 22 22 0.000 1.000 1.000 1.000 1.000 0.679 ! glycolysis GO:0006096 39 39 0.000 1.000 1.000 1.000 1.000 0.808 ! tricarboxylic acid cycle GO:0006099 25 25 0.000 1.000 1.000 1.000 1.000 0.740 ! energy reserve metabolic process GO:0006112 51 51 0.000 1.000 1.000 1.000 1.000 0.811 ! oxidative phosphorylation GO:0006119 24 23 0.000 1.000 1.000 1.000 1.000 0.671 ! purine nucleotide biosynthetic process GO:0006164 103 103 0.000 1.000 1.000 1.000 1.000 0.976 ! GTP catabolic process GO:0006184 153 153 0.000 1.000 1.000 1.000 1.000 0.781 ! regulation of DNA repair GO:0006282 50 48 0.000 1.000 1.000 1.000 1.000 0.824 ! DNA catabolic process GO:0006308 33 33 0.000 1.000 1.000 1.000 1.000 0.763 ! rRNA processing GO:0006364 106 105 0.000 1.000 1.000 1.000 1.000 0.558 ! transcription initiation from RNA polymerase II promoter GO:0006367 28 28 0.000 1.000 1.000 1.000 1.000 0.342 ! mRNA polyadenylation GO:0006378 23 23 0.000 1.000 1.000 1.000 1.000 0.557 ! tRNA metabolic process GO:0006399 128 122 0.000 1.000 1.000 1.000 1.000 0.770 ! RNA catabolic process GO:0006401 93 88 0.000 1.000 1.000 1.000 1.000 0.779 ! mRNA catabolic process GO:0006402 73 68 0.000 1.000 1.000 1.000 1.000 0.700 ! RNA localization GO:0006403 89 89 0.000 1.000 1.000 1.000 1.000 0.772 ! RNA export from nucleus GO:0006405 35 35 0.000 1.000 1.000 1.000 1.000 0.665 ! mRNA export from nucleus GO:0006406 28 28 0.000 1.000 1.000 1.000 1.000 0.598 ! translational initiation GO:0006413 64 63 0.000 1.000 1.000 1.000 1.000 0.0326 ! translational elongation GO:0006414 44 44 0.000 1.000 1.000 1.000 1.000 0.129 ! regulation of translation GO:0006417 190 184 0.000 1.000 1.000 1.000 1.000 0.923 ! tRNA aminoacylation for protein translation GO:0006418 40 40 0.000 1.000 1.000 1.000 1.000 0.793 ! regulation of translational initiation GO:0006446 39 38 0.000 1.000 1.000 1.000 1.000 0.653 ! negative regulation of protein kinase activity GO:0006469 141 140 0.000 1.000 1.000 1.000 1.000 0.968 ! protein methylation GO:0006479 92 87 0.000 1.000 1.000 1.000 1.000 0.931 GO:0008213|protein alkylation, ! protein demethylation GO:0006482 21 20 0.000 1.000 1.000 1.000 1.000 0.640 GO:0008214|protein dealkylation, ! protein N-linked glycosylation GO:0006487 32 32 0.000 1.000 1.000 1.000 1.000 0.600 ! protein lipidation GO:0006497 57 56 0.000 1.000 1.000 1.000 1.000 0.601 ! GPI anchor metabolic process GO:0006505 35 34 0.000 1.000 1.000 1.000 1.000 0.391 ! GPI anchor biosynthetic process GO:0006506 33 32 0.000 1.000 1.000 1.000 1.000 0.359 ! protein monoubiquitination GO:0006513 39 39 0.000 1.000 1.000 1.000 1.000 0.719 ! peptide metabolic process GO:0006518 71 70 0.000 1.000 1.000 1.000 1.000 0.834 ! cellular biogenic amine metabolic process GO:0006576 103 103 0.000 1.000 1.000 1.000 1.000 0.992 ! catecholamine metabolic process GO:0006584 36 36 0.000 1.000 1.000 1.000 1.000 0.855 GO:0009712|catechol-containing compound metabolic process, GO:0034311|diol metabolic process, ! indolalkylamine metabolic process GO:0006586 20 20 0.000 1.000 1.000 1.000 1.000 0.773 GO:0042430|indole-containing compound metabolic process, ! protein export from nucleus GO:0006611 24 23 0.000 1.000 1.000 1.000 1.000 0.442 ! protein targeting to membrane GO:0006612 52 51 0.000 1.000 1.000 1.000 1.000 0.838 ! protein targeting to mitochondrion GO:0006626 32 31 0.000 1.000 1.000 1.000 1.000 0.671 ! fatty acid biosynthetic process GO:0006633 108 107 0.000 1.000 1.000 1.000 1.000 0.951 ! fatty acid beta-oxidation GO:0006635 33 33 0.000 1.000 1.000 1.000 1.000 0.786 ! unsaturated fatty acid biosynthetic process GO:0006636 41 40 0.000 1.000 1.000 1.000 1.000 0.833 ! acyl-CoA metabolic process GO:0006637 33 33 0.000 1.000 1.000 1.000 1.000 0.704 GO:0035383|thioester metabolic process, ! neutral lipid metabolic process GO:0006638 64 64 0.000 1.000 1.000 1.000 1.000 0.877 ! acylglycerol metabolic process GO:0006639 62 62 0.000 1.000 1.000 1.000 1.000 0.878 ! triglyceride metabolic process GO:0006641 50 50 0.000 1.000 1.000 1.000 1.000 0.876 ! membrane lipid metabolic process GO:0006643 94 86 0.000 1.000 1.000 1.000 1.000 0.941 ! glycerophospholipid metabolic process GO:0006650 150 148 0.000 1.000 1.000 1.000 1.000 0.952 ! phosphatidylinositol biosynthetic process GO:0006661 53 52 0.000 1.000 1.000 1.000 1.000 0.727 ! glycerol ether metabolic process GO:0006662 81 81 0.000 1.000 1.000 1.000 1.000 0.877 ! glycolipid metabolic process GO:0006664 31 30 0.000 1.000 1.000 1.000 1.000 0.759 ! sphingolipid metabolic process GO:0006665 91 83 0.000 1.000 1.000 1.000 1.000 0.942 ! ceramide metabolic process GO:0006672 55 51 0.000 1.000 1.000 1.000 1.000 0.817 ! glycosphingolipid metabolic process GO:0006687 26 25 0.000 1.000 1.000 1.000 1.000 0.723 ! icosanoid metabolic process GO:0006690 60 59 0.000 1.000 1.000 1.000 1.000 0.856 ! leukotriene metabolic process GO:0006691 23 23 0.000 1.000 1.000 1.000 1.000 0.706 ! prostanoid metabolic process GO:0006692 25 24 0.000 1.000 1.000 1.000 1.000 0.752 GO:0006693|prostaglandin metabolic process, ! prostaglandin metabolic process GO:0006693 25 24 0.000 1.000 1.000 1.000 1.000 0.752 GO:0006692|prostanoid metabolic process, ! steroid biosynthetic process GO:0006694 89 89 0.000 1.000 1.000 1.000 1.000 0.947 ! cholesterol biosynthetic process GO:0006695 27 27 0.000 1.000 1.000 1.000 1.000 0.695 ! isoprenoid metabolic process GO:0006720 71 71 0.000 1.000 1.000 1.000 1.000 0.865 ! terpenoid metabolic process GO:0006721 47 47 0.000 1.000 1.000 1.000 1.000 0.806 ! coenzyme metabolic process GO:0006732 193 193 0.000 1.000 1.000 1.000 1.000 0.973 ! oxidoreduction coenzyme metabolic process GO:0006733 65 65 0.000 1.000 1.000 1.000 1.000 0.863 ! NADP metabolic process GO:0006739 27 27 0.000 1.000 1.000 1.000 1.000 0.748 ! glutathione metabolic process GO:0006749 43 43 0.000 1.000 1.000 1.000 1.000 0.759 ! ATP biosynthetic process GO:0006754 33 33 0.000 1.000 1.000 1.000 1.000 0.767 ! vitamin metabolic process GO:0006766 71 71 0.000 1.000 1.000 1.000 1.000 0.865 ! water-soluble vitamin metabolic process GO:0006767 21 21 0.000 1.000 1.000 1.000 1.000 0.673 ! fat-soluble vitamin metabolic process GO:0006775 49 49 0.000 1.000 1.000 1.000 1.000 0.823 ! vitamin A metabolic process GO:0006776 36 36 0.000 1.000 1.000 1.000 1.000 0.763 ! porphyrin-containing compound metabolic process GO:0006778 42 39 0.000 1.000 1.000 1.000 1.000 0.789 GO:0033013|tetrapyrrole metabolic process, ! porphyrin-containing compound biosynthetic process GO:0006779 27 24 0.000 1.000 1.000 1.000 1.000 0.709 GO:0033014|tetrapyrrole biosynthetic process, ! superoxide metabolic process GO:0006801 28 28 0.000 1.000 1.000 1.000 1.000 0.799 ! xenobiotic metabolic process GO:0006805 35 35 0.000 1.000 1.000 1.000 1.000 0.737 GO:0071466|cellular response to xenobiotic stimulus, ! potassium ion transport GO:0006813 135 135 0.000 1.000 1.000 1.000 1.000 0.779 ! sodium ion transport GO:0006814 141 133 0.000 1.000 1.000 1.000 1.000 0.916 ! calcium ion transport GO:0006816 178 176 0.000 1.000 1.000 1.000 1.000 0.956 ! hydrogen transport GO:0006818 73 71 0.000 1.000 1.000 1.000 1.000 0.787 ! anion transport GO:0006820 171 169 0.000 1.000 1.000 1.000 1.000 0.917 ! chloride transport GO:0006821 85 85 0.000 1.000 1.000 1.000 1.000 0.666 ! iron ion transport GO:0006826 23 23 0.000 1.000 1.000 1.000 1.000 0.580 ! zinc ion transport GO:0006829 27 27 0.000 1.000 1.000 1.000 1.000 0.342 ! neurotransmitter transport GO:0006836 91 90 0.000 1.000 1.000 1.000 1.000 0.938 ! mitochondrial transport GO:0006839 74 70 0.000 1.000 1.000 1.000 1.000 0.850 ! amino acid transport GO:0006865 100 100 0.000 1.000 1.000 1.000 1.000 0.934 ! lipid transport GO:0006869 146 145 0.000 1.000 1.000 1.000 1.000 0.940 ! cellular iron ion homeostasis GO:0006879 31 31 0.000 1.000 1.000 1.000 1.000 0.565 ! regulation of pH GO:0006885 44 42 0.000 1.000 1.000 1.000 1.000 0.815 ! exocytosis GO:0006887 153 146 0.000 1.000 1.000 1.000 1.000 0.926 ! ER to Golgi vesicle-mediated transport GO:0006888 31 31 0.000 1.000 1.000 1.000 1.000 0.452 ! post-Golgi vesicle-mediated transport GO:0006892 35 34 0.000 1.000 1.000 1.000 1.000 0.620 ! Golgi to plasma membrane transport GO:0006893 26 25 0.000 1.000 1.000 1.000 1.000 0.539 ! membrane budding GO:0006900 21 21 0.000 1.000 1.000 1.000 1.000 0.629 ! vesicle fusion GO:0006906 30 28 0.000 1.000 1.000 1.000 1.000 0.649 ! phagocytosis GO:0006909 73 73 0.000 1.000 1.000 1.000 1.000 0.824 ! autophagy GO:0006914 84 81 0.000 1.000 1.000 1.000 1.000 0.645 ! activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 73 73 0.000 1.000 1.000 1.000 1.000 0.878 ! muscle contraction GO:0006936 118 118 0.000 1.000 1.000 1.000 1.000 0.976 ! regulation of muscle contraction GO:0006937 101 101 0.000 1.000 1.000 1.000 1.000 0.903 ! smooth muscle contraction GO:0006939 41 41 0.000 1.000 1.000 1.000 1.000 0.868 ! regulation of smooth muscle contraction GO:0006940 48 48 0.000 1.000 1.000 1.000 1.000 0.889 ! striated muscle contraction GO:0006941 54 54 0.000 1.000 1.000 1.000 1.000 0.859 ! regulation of striated muscle contraction GO:0006942 47 47 0.000 1.000 1.000 1.000 1.000 0.888 ! cellular membrane fusion GO:0006944 68 65 0.000 1.000 1.000 1.000 1.000 0.814 ! syncytium formation GO:0006949 22 22 0.000 1.000 1.000 1.000 1.000 0.711 ! acute-phase response GO:0006953 33 33 0.000 1.000 1.000 1.000 1.000 0.508 ! complement activation GO:0006956 39 38 0.000 1.000 1.000 1.000 1.000 0.540 ! complement activation, classical pathway GO:0006958 28 28 0.000 1.000 1.000 1.000 1.000 0.525 ! humoral immune response GO:0006959 70 69 0.000 1.000 1.000 1.000 1.000 0.776 ! ER-nucleus signaling pathway GO:0006984 42 41 0.000 1.000 1.000 1.000 1.000 0.771 ! response to unfolded protein GO:0006986 62 60 0.000 1.000 1.000 1.000 1.000 0.688 ! nucleus organization GO:0006997 61 60 0.000 1.000 1.000 1.000 1.000 0.812 ! mitochondrial membrane organization GO:0007006 38 38 0.000 1.000 1.000 1.000 1.000 0.794 ! plasma membrane organization GO:0007009 82 75 0.000 1.000 1.000 1.000 1.000 0.866 ! actin filament organization GO:0007015 100 100 0.000 1.000 1.000 1.000 1.000 0.950 ! microtubule-based movement GO:0007018 138 130 0.000 1.000 1.000 1.000 1.000 0.914 ! negative regulation of microtubule depolymerization GO:0007026 24 21 0.000 1.000 1.000 1.000 1.000 0.564 ! endoplasmic reticulum organization GO:0007029 21 21 0.000 1.000 1.000 1.000 1.000 0.600 ! peroxisome organization GO:0007031 32 32 0.000 1.000 1.000 1.000 1.000 0.743 ! endosome organization GO:0007032 24 23 0.000 1.000 1.000 1.000 1.000 0.452 ! vacuole organization GO:0007033 56 54 0.000 1.000 1.000 1.000 1.000 0.761 ! vacuolar transport GO:0007034 44 44 0.000 1.000 1.000 1.000 1.000 0.658 ! lysosome organization GO:0007040 30 29 0.000 1.000 1.000 1.000 1.000 0.704 ! lysosomal transport GO:0007041 38 38 0.000 1.000 1.000 1.000 1.000 0.664 ! cell-cell junction assembly GO:0007043 30 30 0.000 1.000 1.000 1.000 1.000 0.781 ! cell-substrate junction assembly GO:0007044 29 28 0.000 1.000 1.000 1.000 1.000 0.725 ! cell cycle arrest GO:0007050 96 94 0.000 1.000 1.000 1.000 1.000 0.936 ! mitotic spindle organization GO:0007052 26 25 0.000 1.000 1.000 1.000 1.000 0.646 ! sister chromatid cohesion GO:0007062 26 26 0.000 1.000 1.000 1.000 1.000 0.694 ! regulation of mitosis GO:0007088 75 72 0.000 1.000 1.000 1.000 1.000 0.888 GO:0051783|regulation of nuclear division, ! centrosome cycle GO:0007098 25 24 0.000 1.000 1.000 1.000 1.000 0.612 ! meiotic prophase I GO:0007128 20 20 0.000 1.000 1.000 1.000 1.000 0.573 GO:0051324|prophase, ! synapsis GO:0007129 27 27 0.000 1.000 1.000 1.000 1.000 0.673 ! male meiosis GO:0007140 28 28 0.000 1.000 1.000 1.000 1.000 0.726 ! female meiosis GO:0007143 20 20 0.000 1.000 1.000 1.000 1.000 0.682 ! homophilic cell adhesion GO:0007156 74 73 0.000 1.000 1.000 1.000 1.000 0.113 ! heterophilic cell-cell adhesion GO:0007157 31 30 0.000 1.000 1.000 1.000 1.000 0.457 ! leukocyte cell-cell adhesion GO:0007159 34 34 0.000 1.000 1.000 1.000 1.000 0.808 ! cell-matrix adhesion GO:0007160 74 72 0.000 1.000 1.000 1.000 1.000 0.804 ! establishment or maintenance of cell polarity GO:0007163 102 98 0.000 1.000 1.000 1.000 1.000 0.959 ! epidermal growth factor receptor signaling pathway GO:0007173 24 23 0.000 1.000 1.000 1.000 1.000 0.656 ! regulation of epidermal growth factor-activated receptor activity GO:0007176 20 20 0.000 1.000 1.000 1.000 1.000 0.719 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 108 0.000 1.000 1.000 1.000 1.000 0.986 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 98 0.000 1.000 1.000 1.000 1.000 0.986 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 43 43 0.000 1.000 1.000 1.000 1.000 0.850 ! activation of adenylate cyclase activity GO:0007190 54 54 0.000 1.000 1.000 1.000 1.000 0.865 ! inhibition of adenylate cyclase activity by G-protein signaling pathway GO:0007193 37 37 0.000 1.000 1.000 1.000 1.000 0.813 ! negative regulation of adenylate cyclase activity GO:0007194 41 41 0.000 1.000 1.000 1.000 1.000 0.834 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 49 49 0.000 1.000 1.000 1.000 1.000 0.858 ! activation of phospholipase C activity GO:0007202 59 59 0.000 1.000 1.000 1.000 1.000 0.876 ! elevation of cytosolic calcium ion concentration GO:0007204 162 162 0.000 1.000 1.000 1.000 1.000 0.988 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 28 28 0.000 1.000 1.000 1.000 1.000 0.692 ! dopamine receptor signaling pathway GO:0007212 25 25 0.000 1.000 1.000 1.000 1.000 0.697 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 20 0.000 1.000 1.000 1.000 1.000 0.433 ! glutamate receptor signaling pathway GO:0007215 40 40 0.000 1.000 1.000 1.000 1.000 0.826 ! neuropeptide signaling pathway GO:0007218 95 95 0.000 1.000 1.000 1.000 1.000 0.527 ! Notch signaling pathway GO:0007219 71 71 0.000 1.000 1.000 1.000 1.000 0.756 ! smoothened signaling pathway GO:0007224 54 54 0.000 1.000 1.000 1.000 1.000 0.763 ! integrin-mediated signaling pathway GO:0007229 87 87 0.000 1.000 1.000 1.000 1.000 0.574 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 38 38 0.000 1.000 1.000 1.000 1.000 0.720 ! JNK cascade GO:0007254 59 59 0.000 1.000 1.000 1.000 1.000 0.843 ! activation of JUN kinase activity GO:0007257 28 28 0.000 1.000 1.000 1.000 1.000 0.799 ! JAK-STAT cascade GO:0007259 32 32 0.000 1.000 1.000 1.000 1.000 0.825 ! Ras protein signal transduction GO:0007265 83 83 0.000 1.000 1.000 1.000 1.000 0.757 ! Rho protein signal transduction GO:0007266 38 38 0.000 1.000 1.000 1.000 1.000 0.666 ! neurotransmitter secretion GO:0007269 48 47 0.000 1.000 1.000 1.000 1.000 0.761 ! neuron-neuron synaptic transmission GO:0007270 50 50 0.000 1.000 1.000 1.000 1.000 0.854 ! ensheathment of neurons GO:0007272 89 86 0.000 1.000 1.000 1.000 1.000 0.942 GO:0008366|axon ensheathment, ! germ cell development GO:0007281 143 140 0.000 1.000 1.000 1.000 1.000 0.941 ! spermatid development GO:0007286 86 84 0.000 1.000 1.000 1.000 1.000 0.784 ! female gamete generation GO:0007292 81 81 0.000 1.000 1.000 1.000 1.000 0.862 ! single fertilization GO:0007338 74 73 0.000 1.000 1.000 1.000 1.000 0.700 ! binding of sperm to zona pellucida GO:0007339 32 32 0.000 1.000 1.000 1.000 1.000 0.405 ! determination of left/right symmetry GO:0007368 81 81 0.000 1.000 1.000 1.000 1.000 0.893 ! neuroblast proliferation GO:0007405 23 23 0.000 1.000 1.000 1.000 1.000 0.755 ! synapse assembly GO:0007416 33 32 0.000 1.000 1.000 1.000 1.000 0.773 ! peripheral nervous system development GO:0007422 60 59 0.000 1.000 1.000 1.000 1.000 0.879 ! salivary gland development GO:0007431 30 30 0.000 1.000 1.000 1.000 1.000 0.827 ! salivary gland morphogenesis GO:0007435 27 27 0.000 1.000 1.000 1.000 1.000 0.828 ! mesoderm development GO:0007498 92 92 0.000 1.000 1.000 1.000 1.000 0.897 ! neuromuscular junction development GO:0007528 35 35 0.000 1.000 1.000 1.000 1.000 0.801 ! sex determination GO:0007530 21 21 0.000 1.000 1.000 1.000 1.000 0.705 ! respiratory gaseous exchange GO:0007585 29 29 0.000 1.000 1.000 1.000 1.000 0.728 ! digestion GO:0007586 58 57 0.000 1.000 1.000 1.000 1.000 0.843 ! excretion GO:0007588 24 24 0.000 1.000 1.000 1.000 1.000 0.683 ! blood coagulation GO:0007596 96 94 0.000 1.000 1.000 1.000 1.000 0.931 GO:0050817|coagulation, ! hemostasis GO:0007599 98 96 0.000 1.000 1.000 1.000 1.000 0.931 ! phototransduction GO:0007602 28 27 0.000 1.000 1.000 1.000 1.000 0.628 ! sensory perception of sound GO:0007605 122 118 0.000 1.000 1.000 1.000 1.000 0.932 ! learning or memory GO:0007611 173 172 0.000 1.000 1.000 1.000 1.000 0.986 ! learning GO:0007612 100 99 0.000 1.000 1.000 1.000 1.000 0.992 ! memory GO:0007613 84 83 0.000 1.000 1.000 1.000 1.000 0.898 ! long-term memory GO:0007616 24 24 0.000 1.000 1.000 1.000 1.000 0.773 ! mating behavior GO:0007617 24 24 0.000 1.000 1.000 1.000 1.000 0.791 ! mating GO:0007618 38 38 0.000 1.000 1.000 1.000 1.000 0.842 ! rhythmic behavior GO:0007622 28 28 0.000 1.000 1.000 1.000 1.000 0.831 ! locomotory behavior GO:0007626 165 163 0.000 1.000 1.000 1.000 1.000 0.967 ! adult walking behavior GO:0007628 37 36 0.000 1.000 1.000 1.000 1.000 0.840 ! feeding behavior GO:0007631 82 82 0.000 1.000 1.000 1.000 1.000 0.888 ! visual behavior GO:0007632 45 45 0.000 1.000 1.000 1.000 1.000 0.856 ! regulation of heart contraction GO:0008016 121 120 0.000 1.000 1.000 1.000 1.000 0.998 ! tRNA processing GO:0008033 85 80 0.000 1.000 1.000 1.000 1.000 0.419 ! cell recognition GO:0008037 77 77 0.000 1.000 1.000 1.000 1.000 0.835 ! neuron recognition GO:0008038 24 24 0.000 1.000 1.000 1.000 1.000 0.708 ! motor axon guidance GO:0008045 24 24 0.000 1.000 1.000 1.000 1.000 0.749 ! regulation of actin polymerization or depolymerization GO:0008064 99 95 0.000 1.000 1.000 1.000 1.000 0.945 ! axon cargo transport GO:0008088 35 32 0.000 1.000 1.000 1.000 1.000 0.762 ! actin polymerization or depolymerization GO:0008154 21 21 0.000 1.000 1.000 1.000 1.000 0.633 ! negative regulation of DNA replication GO:0008156 34 34 0.000 1.000 1.000 1.000 1.000 0.752 ! bile acid metabolic process GO:0008206 20 20 0.000 1.000 1.000 1.000 1.000 0.657 ! C21-steroid hormone metabolic process GO:0008207 29 29 0.000 1.000 1.000 1.000 1.000 0.811 ! androgen metabolic process GO:0008209 22 22 0.000 1.000 1.000 1.000 1.000 0.730 ! protein alkylation GO:0008213 92 87 0.000 1.000 1.000 1.000 1.000 0.931 GO:0006479|protein methylation, ! protein dealkylation GO:0008214 21 20 0.000 1.000 1.000 1.000 1.000 0.640 GO:0006482|protein demethylation, ! regulation of blood pressure GO:0008217 154 153 0.000 1.000 1.000 1.000 1.000 0.998 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 99 98 0.000 1.000 1.000 1.000 1.000 0.923 ! isoprenoid biosynthetic process GO:0008299 25 25 0.000 1.000 1.000 1.000 1.000 0.746 ! associative learning GO:0008306 64 63 0.000 1.000 1.000 1.000 1.000 0.893 ! endosome to lysosome transport GO:0008333 28 28 0.000 1.000 1.000 1.000 1.000 0.490 ! adult locomotory behavior GO:0008344 86 84 0.000 1.000 1.000 1.000 1.000 0.877 ! axon ensheathment GO:0008366 89 86 0.000 1.000 1.000 1.000 1.000 0.942 GO:0007272|ensheathment of neurons, ! gonad development GO:0008406 155 154 0.000 1.000 1.000 1.000 1.000 0.983 ! visual learning GO:0008542 42 42 0.000 1.000 1.000 1.000 1.000 0.852 ! fibroblast growth factor receptor signaling pathway GO:0008543 38 38 0.000 1.000 1.000 1.000 1.000 0.767 ! male gonad development GO:0008584 72 71 0.000 1.000 1.000 1.000 1.000 0.885 ! female gonad development GO:0008585 84 84 0.000 1.000 1.000 1.000 1.000 0.892 ! regulation of Notch signaling pathway GO:0008593 41 41 0.000 1.000 1.000 1.000 1.000 0.814 ! apoptotic mitochondrial changes GO:0008637 40 40 0.000 1.000 1.000 1.000 1.000 0.842 ! carbohydrate transport GO:0008643 71 71 0.000 1.000 1.000 1.000 1.000 0.729 ! hexose transport GO:0008645 34 34 0.000 1.000 1.000 1.000 1.000 0.747 ! cellular amino acid biosynthetic process GO:0008652 85 84 0.000 1.000 1.000 1.000 1.000 0.890 ! phospholipid biosynthetic process GO:0008654 127 125 0.000 1.000 1.000 1.000 1.000 0.936 ! aerobic respiration GO:0009060 36 35 0.000 1.000 1.000 1.000 1.000 0.778 ! fatty acid catabolic process GO:0009062 43 43 0.000 1.000 1.000 1.000 1.000 0.816 ! cellular amino acid catabolic process GO:0009063 78 75 0.000 1.000 1.000 1.000 1.000 0.887 ! glutamine family amino acid metabolic process GO:0009064 52 51 0.000 1.000 1.000 1.000 1.000 0.864 ! aspartate family amino acid metabolic process GO:0009066 26 26 0.000 1.000 1.000 1.000 1.000 0.779 ! serine family amino acid metabolic process GO:0009069 32 31 0.000 1.000 1.000 1.000 1.000 0.807 ! aromatic amino acid family metabolic process GO:0009072 23 23 0.000 1.000 1.000 1.000 1.000 0.756 ! coenzyme biosynthetic process GO:0009108 77 77 0.000 1.000 1.000 1.000 1.000 0.880 ! coenzyme catabolic process GO:0009109 36 36 0.000 1.000 1.000 1.000 1.000 0.827 ! vitamin biosynthetic process GO:0009110 20 20 0.000 1.000 1.000 1.000 1.000 0.706 ! nucleoside monophosphate metabolic process GO:0009123 92 90 0.000 1.000 1.000 1.000 1.000 0.975 ! nucleoside monophosphate biosynthetic process GO:0009124 60 59 0.000 1.000 1.000 1.000 1.000 0.850 ! nucleoside monophosphate catabolic process GO:0009125 21 20 0.000 1.000 1.000 1.000 1.000 0.716 ! purine nucleoside monophosphate metabolic process GO:0009126 30 30 0.000 1.000 1.000 1.000 1.000 0.784 ! nucleoside diphosphate metabolic process GO:0009132 36 36 0.000 1.000 1.000 1.000 1.000 0.840 ! purine nucleoside triphosphate biosynthetic process GO:0009145 44 44 0.000 1.000 1.000 1.000 1.000 0.834 ! purine ribonucleotide biosynthetic process GO:0009152 65 65 0.000 1.000 1.000 1.000 1.000 0.877 ! ribonucleoside monophosphate biosynthetic process GO:0009156 24 24 0.000 1.000 1.000 1.000 1.000 0.775 ! ribonucleoside monophosphate metabolic process GO:0009161 34 34 0.000 1.000 1.000 1.000 1.000 0.820 ! purine ribonucleoside monophosphate metabolic process GO:0009167 29 29 0.000 1.000 1.000 1.000 1.000 0.783 ! ribonucleoside diphosphate metabolic process GO:0009185 20 20 0.000 1.000 1.000 1.000 1.000 0.765 ! cyclic nucleotide metabolic process GO:0009187 51 50 0.000 1.000 1.000 1.000 1.000 0.821 ! cyclic nucleotide biosynthetic process GO:0009190 33 32 0.000 1.000 1.000 1.000 1.000 0.715 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 43 43 0.000 1.000 1.000 1.000 1.000 0.830 ! nucleotide-sugar metabolic process GO:0009225 22 22 0.000 1.000 1.000 1.000 1.000 0.711 ! deoxyribonucleotide metabolic process GO:0009262 26 25 0.000 1.000 1.000 1.000 1.000 0.836 ! cellular response to starvation GO:0009267 68 67 0.000 1.000 1.000 1.000 1.000 0.828 ! response to pH GO:0009268 24 24 0.000 1.000 1.000 1.000 1.000 0.708 ! protein secretion GO:0009306 46 45 0.000 1.000 1.000 1.000 1.000 0.791 ! amine biosynthetic process GO:0009309 124 123 0.000 1.000 1.000 1.000 1.000 0.991 ! amine catabolic process GO:0009310 89 86 0.000 1.000 1.000 1.000 1.000 0.895 ! oligosaccharide metabolic process GO:0009311 32 32 0.000 1.000 1.000 1.000 1.000 0.704 ! phospholipid catabolic process GO:0009395 27 27 0.000 1.000 1.000 1.000 1.000 0.695 ! response to xenobiotic stimulus GO:0009410 39 39 0.000 1.000 1.000 1.000 1.000 0.756 ! RNA modification GO:0009451 55 53 0.000 1.000 1.000 1.000 1.000 0.694 ! fertilization GO:0009566 112 109 0.000 1.000 1.000 1.000 1.000 0.918 ! detection of external stimulus GO:0009581 102 99 0.000 1.000 1.000 1.000 1.000 0.981 ! detection of abiotic stimulus GO:0009582 81 78 0.000 1.000 1.000 1.000 1.000 0.881 ! detection of light stimulus GO:0009583 36 35 0.000 1.000 1.000 1.000 1.000 0.697 ! detection of chemical stimulus GO:0009593 59 57 0.000 1.000 1.000 1.000 1.000 0.777 ! detection of biotic stimulus GO:0009595 27 27 0.000 1.000 1.000 1.000 1.000 0.810 ! response to mechanical stimulus GO:0009612 65 62 0.000 1.000 1.000 1.000 1.000 0.888 ! response to virus GO:0009615 156 152 0.000 1.000 1.000 1.000 1.000 0.919 ! response to fungus GO:0009620 24 24 0.000 1.000 1.000 1.000 1.000 0.721 ! response to toxin GO:0009636 69 69 0.000 1.000 1.000 1.000 1.000 0.854 ! catechol-containing compound metabolic process GO:0009712 36 36 0.000 1.000 1.000 1.000 1.000 0.855 GO:0034311|diol metabolic process, GO:0006584|catecholamine metabolic process, ! response to carbohydrate stimulus GO:0009743 77 77 0.000 1.000 1.000 1.000 1.000 0.885 ! response to hexose stimulus GO:0009746 69 69 0.000 1.000 1.000 1.000 1.000 0.871 ! response to glucose stimulus GO:0009749 68 68 0.000 1.000 1.000 1.000 1.000 0.869 ! hormone-mediated signaling pathway GO:0009755 72 72 0.000 1.000 1.000 1.000 1.000 0.871 ! axis specification GO:0009798 82 82 0.000 1.000 1.000 1.000 1.000 0.901 ! specification of symmetry GO:0009799 88 88 0.000 1.000 1.000 1.000 1.000 0.898 ! determination of bilateral symmetry GO:0009855 87 87 0.000 1.000 1.000 1.000 1.000 0.897 ! embryonic pattern specification GO:0009880 51 51 0.000 1.000 1.000 1.000 1.000 0.853 ! negative regulation of catabolic process GO:0009895 84 83 0.000 1.000 1.000 1.000 1.000 0.890 ! hormone transport GO:0009914 73 72 0.000 1.000 1.000 1.000 1.000 0.885 ! anterior/posterior axis specification GO:0009948 39 39 0.000 1.000 1.000 1.000 1.000 0.873 ! dorsal/ventral pattern formation GO:0009953 91 91 0.000 1.000 1.000 1.000 1.000 0.895 ! proximal/distal pattern formation GO:0009954 28 28 0.000 1.000 1.000 1.000 1.000 0.713 ! cell-cell recognition GO:0009988 37 37 0.000 1.000 1.000 1.000 1.000 0.542 ! oocyte differentiation GO:0009994 29 29 0.000 1.000 1.000 1.000 1.000 0.811 ! response to metal ion GO:0010038 158 157 0.000 1.000 1.000 1.000 1.000 0.975 ! response to gamma radiation GO:0010332 30 30 0.000 1.000 1.000 1.000 1.000 0.826 ! regulation of cell fate commitment GO:0010453 27 27 0.000 1.000 1.000 1.000 1.000 0.843 ! regulation of mesenchymal cell proliferation GO:0010464 42 42 0.000 1.000 1.000 1.000 1.000 0.870 ! regulation of receptor activity GO:0010469 72 72 0.000 1.000 1.000 1.000 1.000 0.887 ! regulation of autophagy GO:0010506 52 50 0.000 1.000 1.000 1.000 1.000 0.768 ! positive regulation of autophagy GO:0010508 22 21 0.000 1.000 1.000 1.000 1.000 0.597 ! regulation of phospholipase activity GO:0010517 78 78 0.000 1.000 1.000 1.000 1.000 0.897 ! positive regulation of phospholipase activity GO:0010518 72 72 0.000 1.000 1.000 1.000 1.000 0.893 ! regulation of calcium ion transport into cytosol GO:0010522 52 52 0.000 1.000 1.000 1.000 1.000 0.881 ! positive regulation of calcium ion transport into cytosol GO:0010524 29 29 0.000 1.000 1.000 1.000 1.000 0.810 ! regulation of platelet activation GO:0010543 21 21 0.000 1.000 1.000 1.000 1.000 0.803 ! regulation of glycoprotein biosynthetic process GO:0010559 26 24 0.000 1.000 1.000 1.000 1.000 0.807 ! negative regulation of phosphorus metabolic process GO:0010563 116 114 0.000 1.000 1.000 1.000 1.000 0.990 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 89 89 0.000 1.000 1.000 1.000 1.000 0.902 ! regulation of vascular endothelial growth factor production GO:0010574 20 20 0.000 1.000 1.000 1.000 1.000 0.818 ! regulation of adenylate cyclase activity involved in G-protein signaling pathway GO:0010578 45 45 0.000 1.000 1.000 1.000 1.000 0.855 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, ! positive regulation of adenylate cyclase activity by G-protein signaling pathway GO:0010579 45 45 0.000 1.000 1.000 1.000 1.000 0.855 GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling pathway, ! positive regulation of endothelial cell migration GO:0010595 40 40 0.000 1.000 1.000 1.000 1.000 0.871 ! regulation of cardiac muscle hypertrophy GO:0010611 22 22 0.000 1.000 1.000 1.000 1.000 0.777 ! regulation of epithelial cell migration GO:0010632 24 24 0.000 1.000 1.000 1.000 1.000 0.833 ! negative regulation of muscle cell apoptosis GO:0010656 24 24 0.000 1.000 1.000 1.000 1.000 0.868 ! regulation of muscle cell apoptosis GO:0010660 37 36 0.000 1.000 1.000 1.000 1.000 0.880 ! positive regulation of cellular carbohydrate metabolic process GO:0010676 47 45 0.000 1.000 1.000 1.000 1.000 0.878 ! negative regulation of cellular carbohydrate metabolic process GO:0010677 21 21 0.000 1.000 1.000 1.000 1.000 0.793 ! regulation of collagen metabolic process GO:0010712 27 26 0.000 1.000 1.000 1.000 1.000 0.848 ! positive regulation of collagen metabolic process GO:0010714 23 22 0.000 1.000 1.000 1.000 1.000 0.827 ! regulation of epithelial to mesenchymal transition GO:0010717 39 38 0.000 1.000 1.000 1.000 1.000 0.877 ! positive regulation of epithelial to mesenchymal transition GO:0010718 24 23 0.000 1.000 1.000 1.000 1.000 0.822 ! negative regulation of cell development GO:0010721 111 111 0.000 1.000 1.000 1.000 1.000 0.995 ! positive regulation of sodium ion transport GO:0010765 23 22 0.000 1.000 1.000 1.000 1.000 0.699 ! regulation of cell morphogenesis involved in differentiation GO:0010769 201 197 0.000 1.000 1.000 1.000 1.000 0.986 ! positive regulation of cell morphogenesis involved in differentiation GO:0010770 33 32 0.000 1.000 1.000 1.000 1.000 0.853 ! regulation of peptidyl-threonine phosphorylation GO:0010799 23 22 0.000 1.000 1.000 1.000 1.000 0.787 ! regulation of cell-substrate adhesion GO:0010810 107 105 0.000 1.000 1.000 1.000 1.000 0.960 ! positive regulation of cell-substrate adhesion GO:0010811 63 61 0.000 1.000 1.000 1.000 1.000 0.801 ! negative regulation of cell-substrate adhesion GO:0010812 31 31 0.000 1.000 1.000 1.000 1.000 0.821 ! regulation of hormone levels GO:0010817 202 200 0.000 1.000 1.000 1.000 1.000 0.980 ! regulation of mitochondrion organization GO:0010821 47 44 0.000 1.000 1.000 1.000 1.000 0.842 ! positive regulation of mitochondrion organization GO:0010822 28 26 0.000 1.000 1.000 1.000 1.000 0.759 ! regulation of glucose transport GO:0010827 63 60 0.000 1.000 1.000 1.000 1.000 0.873 ! positive regulation of glucose transport GO:0010828 38 37 0.000 1.000 1.000 1.000 1.000 0.837 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 25 25 0.000 1.000 1.000 1.000 1.000 0.830 ! positive regulation of phospholipase C activity GO:0010863 64 64 0.000 1.000 1.000 1.000 1.000 0.885 ! lipid localization GO:0010876 162 161 0.000 1.000 1.000 1.000 1.000 0.945 ! regulation of lipid storage GO:0010883 30 30 0.000 1.000 1.000 1.000 1.000 0.783 ! positive regulation of glucose metabolic process GO:0010907 31 31 0.000 1.000 1.000 1.000 1.000 0.840 ! regulation of phosphatase activity GO:0010921 97 94 0.000 1.000 1.000 1.000 1.000 0.672 ! negative regulation of phosphatase activity GO:0010923 67 65 0.000 1.000 1.000 1.000 1.000 0.284 ! cellular component assembly involved in morphogenesis GO:0010927 151 144 0.000 1.000 1.000 1.000 1.000 0.933 ! negative regulation of cell cycle process GO:0010948 81 79 0.000 1.000 1.000 1.000 1.000 0.882 ! positive regulation of endopeptidase activity GO:0010950 109 108 0.000 1.000 1.000 1.000 1.000 0.976 ! positive regulation of peptidase activity GO:0010952 120 119 0.000 1.000 1.000 1.000 1.000 0.966 ! regulation of metal ion transport GO:0010959 203 200 0.000 1.000 1.000 1.000 1.000 0.993 ! regulation of glucan biosynthetic process GO:0010962 27 27 0.000 1.000 1.000 1.000 1.000 0.804 GO:0005979|regulation of glycogen biosynthetic process, ! microtubule-based transport GO:0010970 64 58 0.000 1.000 1.000 1.000 1.000 0.835 GO:0030705|cytoskeleton-dependent intracellular transport, ! positive regulation of neuron projection development GO:0010976 88 86 0.000 1.000 1.000 1.000 1.000 0.886 ! negative regulation of neuron projection development GO:0010977 34 34 0.000 1.000 1.000 1.000 1.000 0.751 ! oligodendrocyte development GO:0014003 29 27 0.000 1.000 1.000 1.000 1.000 0.786 ! negative regulation of gliogenesis GO:0014014 32 32 0.000 1.000 1.000 1.000 1.000 0.840 ! neural crest cell development GO:0014032 52 52 0.000 1.000 1.000 1.000 1.000 0.889 ! neural crest cell differentiation GO:0014033 58 58 0.000 1.000 1.000 1.000 1.000 0.895 ! Schwann cell differentiation GO:0014037 25 24 0.000 1.000 1.000 1.000 1.000 0.745 ! positive regulation of phosphatidylinositol 3-kinase cascade GO:0014068 43 43 0.000 1.000 1.000 1.000 1.000 0.875 ! response to organic cyclic compound GO:0014070 125 125 0.000 1.000 1.000 1.000 1.000 0.998 ! response to tropane GO:0014073 23 23 0.000 1.000 1.000 1.000 1.000 0.842 GO:0042220|response to cocaine, ! regulation of muscle hypertrophy GO:0014743 23 23 0.000 1.000 1.000 1.000 1.000 0.777 ! myotube differentiation GO:0014902 25 25 0.000 1.000 1.000 1.000 1.000 0.768 ! regulation of smooth muscle cell migration GO:0014910 39 39 0.000 1.000 1.000 1.000 1.000 0.874 ! positive regulation of smooth muscle cell migration GO:0014911 26 26 0.000 1.000 1.000 1.000 1.000 0.828 ! organic cation transport GO:0015695 22 22 0.000 1.000 1.000 1.000 1.000 0.709 ! inorganic anion transport GO:0015698 112 112 0.000 1.000 1.000 1.000 1.000 0.781 ! organic anion transport GO:0015711 60 58 0.000 1.000 1.000 1.000 1.000 0.792 ! monocarboxylic acid transport GO:0015718 65 61 0.000 1.000 1.000 1.000 1.000 0.852 ! monosaccharide transport GO:0015749 35 35 0.000 1.000 1.000 1.000 1.000 0.744 ! glucose transport GO:0015758 33 33 0.000 1.000 1.000 1.000 1.000 0.749 ! neutral amino acid transport GO:0015804 21 21 0.000 1.000 1.000 1.000 1.000 0.630 ! L-amino acid transport GO:0015807 31 31 0.000 1.000 1.000 1.000 1.000 0.769 ! peptide transport GO:0015833 66 66 0.000 1.000 1.000 1.000 1.000 0.871 ! amine transport GO:0015837 139 139 0.000 1.000 1.000 1.000 1.000 0.955 ! monoamine transport GO:0015844 23 23 0.000 1.000 1.000 1.000 1.000 0.815 ! organic acid transport GO:0015849 173 169 0.000 1.000 1.000 1.000 1.000 0.949 ! organic alcohol transport GO:0015850 25 25 0.000 1.000 1.000 1.000 1.000 0.801 ! drug transport GO:0015893 24 24 0.000 1.000 1.000 1.000 1.000 0.695 ! fatty acid transport GO:0015908 39 39 0.000 1.000 1.000 1.000 1.000 0.839 ! long-chain fatty acid transport GO:0015909 26 26 0.000 1.000 1.000 1.000 1.000 0.797 ! phospholipid transport GO:0015914 34 34 0.000 1.000 1.000 1.000 1.000 0.728 ! sterol transport GO:0015918 40 40 0.000 1.000 1.000 1.000 1.000 0.841 GO:0030301|cholesterol transport, ! nucleobase-containing compound transport GO:0015931 99 99 0.000 1.000 1.000 1.000 1.000 0.927 ! energy derivation by oxidation of organic compounds GO:0015980 128 127 0.000 1.000 1.000 1.000 1.000 0.952 ! energy coupled proton transport, against electrochemical gradient GO:0015988 25 25 0.000 1.000 1.000 1.000 1.000 0.590 GO:0015991|ATP hydrolysis coupled proton transport, ! ATP hydrolysis coupled proton transport GO:0015991 25 25 0.000 1.000 1.000 1.000 1.000 0.590 GO:0015988|energy coupled proton transport, against electrochemical gradient, ! proton transport GO:0015992 72 70 0.000 1.000 1.000 1.000 1.000 0.794 ! lipid catabolic process GO:0016042 182 181 0.000 1.000 1.000 1.000 1.000 0.927 ! cell growth GO:0016049 75 73 0.000 1.000 1.000 1.000 1.000 0.863 ! carbohydrate biosynthetic process GO:0016051 118 118 0.000 1.000 1.000 1.000 1.000 0.975 ! carbohydrate catabolic process GO:0016052 107 107 0.000 1.000 1.000 1.000 1.000 0.979 ! organic acid catabolic process GO:0016054 131 128 0.000 1.000 1.000 1.000 1.000 0.981 GO:0046395|carboxylic acid catabolic process, ! rRNA metabolic process GO:0016072 110 109 0.000 1.000 1.000 1.000 1.000 0.596 ! synaptic vesicle exocytosis GO:0016079 24 23 0.000 1.000 1.000 1.000 1.000 0.668 ! diterpenoid metabolic process GO:0016101 40 40 0.000 1.000 1.000 1.000 1.000 0.761 GO:0001523|retinoid metabolic process, ! sterol biosynthetic process GO:0016126 33 33 0.000 1.000 1.000 1.000 1.000 0.664 ! endosome transport GO:0016197 109 101 0.000 1.000 1.000 1.000 1.000 0.763 ! macroautophagy GO:0016236 30 29 0.000 1.000 1.000 1.000 1.000 0.545 ! dendrite development GO:0016358 70 68 0.000 1.000 1.000 1.000 1.000 0.848 ! posttranscriptional gene silencing GO:0016441 56 51 0.000 1.000 1.000 1.000 1.000 0.664 ! histone methylation GO:0016571 60 59 0.000 1.000 1.000 1.000 1.000 0.817 ! histone ubiquitination GO:0016574 29 29 0.000 1.000 1.000 1.000 1.000 0.704 ! protein deubiquitination GO:0016579 68 62 0.000 1.000 1.000 1.000 1.000 0.583 ! stem cell division GO:0017145 26 26 0.000 1.000 1.000 1.000 1.000 0.830 ! negative regulation of translation GO:0017148 71 66 0.000 1.000 1.000 1.000 1.000 0.822 ! calcium ion-dependent exocytosis GO:0017156 30 28 0.000 1.000 1.000 1.000 1.000 0.635 ! regulation of exocytosis GO:0017157 94 94 0.000 1.000 1.000 1.000 1.000 0.958 ! regulation of calcium ion-dependent exocytosis GO:0017158 27 27 0.000 1.000 1.000 1.000 1.000 0.740 ! peptidyl-lysine methylation GO:0018022 30 29 0.000 1.000 1.000 1.000 1.000 0.691 ! peptidyl-serine phosphorylation GO:0018105 81 81 0.000 1.000 1.000 1.000 1.000 0.872 ! peptidyl-tyrosine phosphorylation GO:0018108 69 69 0.000 1.000 1.000 1.000 1.000 0.879 ! peptide cross-linking GO:0018149 28 27 0.000 1.000 1.000 1.000 1.000 0.378 ! peptidyl-serine modification GO:0018209 96 94 0.000 1.000 1.000 1.000 1.000 0.953 ! peptidyl-tyrosine modification GO:0018212 71 71 0.000 1.000 1.000 1.000 1.000 0.882 ! organic ether metabolic process GO:0018904 84 84 0.000 1.000 1.000 1.000 1.000 0.882 ! phenol-containing compound metabolic process GO:0018958 53 52 0.000 1.000 1.000 1.000 1.000 0.876 ! virus-host interaction GO:0019048 47 47 0.000 1.000 1.000 1.000 1.000 0.810 ! reproductive behavior GO:0019098 31 31 0.000 1.000 1.000 1.000 1.000 0.815 ! regulation of fatty acid metabolic process GO:0019217 57 57 0.000 1.000 1.000 1.000 1.000 0.890 ! regulation of steroid metabolic process GO:0019218 69 68 0.000 1.000 1.000 1.000 1.000 0.896 ! cytokine-mediated signaling pathway GO:0019221 150 148 0.000 1.000 1.000 1.000 1.000 0.957 ! regulation of action potential in neuron GO:0019228 111 108 0.000 1.000 1.000 1.000 1.000 0.949 ! regulation of vasoconstriction GO:0019229 56 55 0.000 1.000 1.000 1.000 1.000 0.893 ! sensory perception of pain GO:0019233 79 78 0.000 1.000 1.000 1.000 1.000 0.894 ! response to pheromone GO:0019236 104 104 0.000 1.000 1.000 1.000 1.000 0.000558 ! hexose metabolic process GO:0019318 154 153 0.000 1.000 1.000 1.000 1.000 0.972 ! hexose biosynthetic process GO:0019319 31 31 0.000 1.000 1.000 1.000 1.000 0.774 ! hexose catabolic process GO:0019320 55 55 0.000 1.000 1.000 1.000 1.000 0.851 ! pyridine nucleotide metabolic process GO:0019362 55 55 0.000 1.000 1.000 1.000 1.000 0.857 GO:0072524|pyridine-containing compound metabolic process, ! arachidonic acid metabolic process GO:0019369 20 20 0.000 1.000 1.000 1.000 1.000 0.699 ! fatty acid oxidation GO:0019395 51 51 0.000 1.000 1.000 1.000 1.000 0.851 ! alditol metabolic process GO:0019400 28 28 0.000 1.000 1.000 1.000 1.000 0.648 ! aromatic compound biosynthetic process GO:0019438 31 31 0.000 1.000 1.000 1.000 1.000 0.808 ! aromatic compound catabolic process GO:0019439 26 26 0.000 1.000 1.000 1.000 1.000 0.771 ! NAD metabolic process GO:0019674 29 29 0.000 1.000 1.000 1.000 1.000 0.783 ! calcium-mediated signaling GO:0019722 58 56 0.000 1.000 1.000 1.000 1.000 0.829 ! secondary metabolic process GO:0019748 31 31 0.000 1.000 1.000 1.000 1.000 0.771 ! polyol metabolic process GO:0019751 39 39 0.000 1.000 1.000 1.000 1.000 0.735 ! cytolysis GO:0019835 24 24 0.000 1.000 1.000 1.000 1.000 0.217 ! antigen processing and presentation GO:0019882 58 58 0.000 1.000 1.000 1.000 1.000 0.810 ! antigen processing and presentation of exogenous antigen GO:0019884 26 26 0.000 1.000 1.000 1.000 1.000 0.771 ! lipid storage GO:0019915 22 22 0.000 1.000 1.000 1.000 1.000 0.753 ! cAMP-mediated signaling GO:0019933 111 111 0.000 1.000 1.000 1.000 1.000 0.982 ! cyclic-nucleotide-mediated signaling GO:0019935 123 123 0.000 1.000 1.000 1.000 1.000 0.985 ! spinal cord development GO:0021510 78 77 0.000 1.000 1.000 1.000 1.000 0.859 ! spinal cord patterning GO:0021511 22 22 0.000 1.000 1.000 1.000 1.000 0.730 ! cell differentiation in spinal cord GO:0021515 55 54 0.000 1.000 1.000 1.000 1.000 0.835 ! dorsal spinal cord development GO:0021516 21 20 0.000 1.000 1.000 1.000 1.000 0.558 ! ventral spinal cord development GO:0021517 41 41 0.000 1.000 1.000 1.000 1.000 0.793 ! spinal cord motor neuron differentiation GO:0021522 37 37 0.000 1.000 1.000 1.000 1.000 0.778 ! neural tube patterning GO:0021532 36 36 0.000 1.000 1.000 1.000 1.000 0.839 ! cell differentiation in hindbrain GO:0021533 22 22 0.000 1.000 1.000 1.000 1.000 0.784 ! cerebellum development GO:0021549 67 65 0.000 1.000 1.000 1.000 1.000 0.866 ! hindbrain morphogenesis GO:0021575 40 39 0.000 1.000 1.000 1.000 1.000 0.847 ! cerebellum morphogenesis GO:0021587 36 35 0.000 1.000 1.000 1.000 1.000 0.834 ! cranial nerve morphogenesis GO:0021602 21 21 0.000 1.000 1.000 1.000 1.000 0.813 ! cerebellar Purkinje cell layer development GO:0021680 23 22 0.000 1.000 1.000 1.000 1.000 0.722 ! cerebellar cortex development GO:0021695 40 39 0.000 1.000 1.000 1.000 1.000 0.834 ! cerebellar cortex morphogenesis GO:0021696 28 27 0.000 1.000 1.000 1.000 1.000 0.794 ! developmental maturation GO:0021700 170 168 0.000 1.000 1.000 1.000 1.000 0.980 ! glial cell development GO:0021782 66 63 0.000 1.000 1.000 1.000 1.000 0.887 ! cerebral cortex cell migration GO:0021795 30 30 0.000 1.000 1.000 1.000 1.000 0.867 ! cell proliferation in forebrain GO:0021846 28 28 0.000 1.000 1.000 1.000 1.000 0.786 ! forebrain generation of neurons GO:0021872 39 39 0.000 1.000 1.000 1.000 1.000 0.874 ! forebrain neuron differentiation GO:0021879 28 28 0.000 1.000 1.000 1.000 1.000 0.831 ! forebrain cell migration GO:0021885 43 43 0.000 1.000 1.000 1.000 1.000 0.890 ! dorsal/ventral neural tube patterning GO:0021904 20 20 0.000 1.000 1.000 1.000 1.000 0.735 ! central nervous system projection neuron axonogenesis GO:0021952 23 22 0.000 1.000 1.000 1.000 1.000 0.739 ! central nervous system neuron differentiation GO:0021953 146 143 0.000 1.000 1.000 1.000 1.000 0.989 ! central nervous system neuron development GO:0021954 60 58 0.000 1.000 1.000 1.000 1.000 0.879 ! central nervous system neuron axonogenesis GO:0021955 32 30 0.000 1.000 1.000 1.000 1.000 0.803 ! cerebral cortex development GO:0021987 65 64 0.000 1.000 1.000 1.000 1.000 0.889 ! telencephalon cell migration GO:0022029 40 40 0.000 1.000 1.000 1.000 1.000 0.890 ! metencephalon development GO:0022037 78 76 0.000 1.000 1.000 1.000 1.000 0.884 ! membrane docking GO:0022406 27 25 0.000 1.000 1.000 1.000 1.000 0.658 ! positive regulation of cell-cell adhesion GO:0022409 34 32 0.000 1.000 1.000 1.000 1.000 0.835 ! cellular process involved in reproduction in multicellular organism GO:0022412 22 21 0.000 1.000 1.000 1.000 1.000 0.552 ! digestive system process GO:0022600 38 38 0.000 1.000 1.000 1.000 1.000 0.828 ! ovulation cycle process GO:0022602 78 78 0.000 1.000 1.000 1.000 1.000 0.893 ! gland morphogenesis GO:0022612 101 101 0.000 1.000 1.000 1.000 1.000 0.903 ! ribonucleoprotein complex assembly GO:0022618 75 74 0.000 1.000 1.000 1.000 1.000 0.803 ! regulation of transmembrane transporter activity GO:0022898 54 52 0.000 1.000 1.000 1.000 1.000 0.884 ! electron transport chain GO:0022900 112 112 0.000 1.000 1.000 1.000 1.000 0.718 ! respiratory electron transport chain GO:0022904 30 30 0.000 1.000 1.000 1.000 1.000 0.719 ! signal transduction by phosphorylation GO:0023014 37 37 0.000 1.000 1.000 1.000 1.000 0.787 ! termination of signal transduction GO:0023021 36 36 0.000 1.000 1.000 1.000 1.000 0.272 ! adaptation of signaling pathway GO:0023058 21 21 0.000 1.000 1.000 1.000 1.000 0.783 ! signal release GO:0023061 125 123 0.000 1.000 1.000 1.000 1.000 0.977 GO:0003001|generation of a signal involved in cell-cell signaling, ! cellular monovalent inorganic cation homeostasis GO:0030004 34 33 0.000 1.000 1.000 1.000 1.000 0.812 ! establishment of cell polarity GO:0030010 69 65 0.000 1.000 1.000 1.000 1.000 0.853 ! cell projection assembly GO:0030031 167 162 0.000 1.000 1.000 1.000 1.000 0.920 ! lamellipodium assembly GO:0030032 28 27 0.000 1.000 1.000 1.000 1.000 0.540 ! actin filament-based movement GO:0030048 25 25 0.000 1.000 1.000 1.000 1.000 0.695 ! regulation of mitotic metaphase/anaphase transition GO:0030071 25 25 0.000 1.000 1.000 1.000 1.000 0.746 ! peptide hormone secretion GO:0030072 48 48 0.000 1.000 1.000 1.000 1.000 0.846 ! insulin secretion GO:0030073 34 34 0.000 1.000 1.000 1.000 1.000 0.794 ! regulation of endocytosis GO:0030100 135 135 0.000 1.000 1.000 1.000 1.000 0.976 ! natural killer cell activation GO:0030101 31 30 0.000 1.000 1.000 1.000 1.000 0.708 ! sphingolipid biosynthetic process GO:0030148 42 37 0.000 1.000 1.000 1.000 1.000 0.744 ! proteoglycan biosynthetic process GO:0030166 29 29 0.000 1.000 1.000 1.000 1.000 0.751 ! platelet activation GO:0030168 37 36 0.000 1.000 1.000 1.000 1.000 0.815 ! B cell differentiation GO:0030183 67 67 0.000 1.000 1.000 1.000 1.000 0.862 ! regulation of blood coagulation GO:0030193 53 53 0.000 1.000 1.000 1.000 1.000 0.876 GO:1900046|regulation of hemostasis, ! negative regulation of blood coagulation GO:0030195 25 25 0.000 1.000 1.000 1.000 1.000 0.726 GO:1900047|negative regulation of hemostasis, ! glycosaminoglycan metabolic process GO:0030203 63 62 0.000 1.000 1.000 1.000 1.000 0.844 ! T cell differentiation GO:0030217 114 114 0.000 1.000 1.000 1.000 1.000 0.978 ! myofibril assembly GO:0030239 34 34 0.000 1.000 1.000 1.000 1.000 0.794 ! lipid modification GO:0030258 111 111 0.000 1.000 1.000 1.000 1.000 0.970 ! regulation of ossification GO:0030278 179 177 0.000 1.000 1.000 1.000 1.000 0.966 ! negative regulation of ossification GO:0030279 32 32 0.000 1.000 1.000 1.000 1.000 0.838 ! bone mineralization GO:0030282 30 30 0.000 1.000 1.000 1.000 1.000 0.729 ! cholesterol transport GO:0030301 40 40 0.000 1.000 1.000 1.000 1.000 0.841 GO:0015918|sterol transport, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 49 0.000 1.000 1.000 1.000 1.000 0.845 ! ER-associated protein catabolic process GO:0030433 35 34 0.000 1.000 1.000 1.000 1.000 0.448 ! regulation of bone mineralization GO:0030500 62 60 0.000 1.000 1.000 1.000 1.000 0.856 ! positive regulation of bone mineralization GO:0030501 29 28 0.000 1.000 1.000 1.000 1.000 0.847 ! BMP signaling pathway GO:0030509 64 64 0.000 1.000 1.000 1.000 1.000 0.810 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 22 0.000 1.000 1.000 1.000 1.000 0.769 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 42 42 0.000 1.000 1.000 1.000 1.000 0.741 ! positive regulation of BMP signaling pathway GO:0030513 29 29 0.000 1.000 1.000 1.000 1.000 0.814 ! regulation of axon extension GO:0030516 48 47 0.000 1.000 1.000 1.000 1.000 0.841 ! negative regulation of axon extension GO:0030517 20 20 0.000 1.000 1.000 1.000 1.000 0.743 ! adult behavior GO:0030534 135 131 0.000 1.000 1.000 1.000 1.000 0.970 ! male genitalia development GO:0030539 21 21 0.000 1.000 1.000 1.000 1.000 0.764 ! neutrophil chemotaxis GO:0030593 34 33 0.000 1.000 1.000 1.000 1.000 0.745 ! leukocyte chemotaxis GO:0030595 75 74 0.000 1.000 1.000 1.000 1.000 0.883 ! regulation of cellular pH GO:0030641 24 23 0.000 1.000 1.000 1.000 1.000 0.746 ! cytoskeleton-dependent intracellular transport GO:0030705 64 58 0.000 1.000 1.000 1.000 1.000 0.834 GO:0010970|microtubule-based transport, ! regulation of cyclic nucleotide metabolic process GO:0030799 158 157 0.000 1.000 1.000 1.000 1.000 0.984 ! negative regulation of cyclic nucleotide metabolic process GO:0030800 52 52 0.000 1.000 1.000 1.000 1.000 0.867 GO:0030815|negative regulation of cAMP metabolic process, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 97 96 0.000 1.000 1.000 1.000 1.000 0.983 ! regulation of cyclic nucleotide biosynthetic process GO:0030802 146 145 0.000 1.000 1.000 1.000 1.000 0.989 ! negative regulation of cyclic nucleotide biosynthetic process GO:0030803 51 51 0.000 1.000 1.000 1.000 1.000 0.868 GO:0030818|negative regulation of cAMP biosynthetic process, ! positive regulation of cyclic nucleotide biosynthetic process GO:0030804 93 92 0.000 1.000 1.000 1.000 1.000 0.895 ! regulation of nucleotide biosynthetic process GO:0030808 148 147 0.000 1.000 1.000 1.000 1.000 0.989 ! negative regulation of nucleotide biosynthetic process GO:0030809 52 52 0.000 1.000 1.000 1.000 1.000 0.870 ! positive regulation of nucleotide biosynthetic process GO:0030810 95 94 0.000 1.000 1.000 1.000 1.000 0.988 ! regulation of cAMP metabolic process GO:0030814 134 134 0.000 1.000 1.000 1.000 1.000 0.984 ! negative regulation of cAMP metabolic process GO:0030815 52 52 0.000 1.000 1.000 1.000 1.000 0.867 GO:0030800|negative regulation of cyclic nucleotide metabolic process, ! positive regulation of cAMP metabolic process GO:0030816 84 84 0.000 1.000 1.000 1.000 1.000 0.890 ! regulation of cAMP biosynthetic process GO:0030817 127 127 0.000 1.000 1.000 1.000 1.000 0.988 ! negative regulation of cAMP biosynthetic process GO:0030818 51 51 0.000 1.000 1.000 1.000 1.000 0.868 GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 82 82 0.000 1.000 1.000 1.000 1.000 0.892 ! regulation of cGMP metabolic process GO:0030823 24 23 0.000 1.000 1.000 1.000 1.000 0.739 ! regulation of actin filament length GO:0030832 100 96 0.000 1.000 1.000 1.000 1.000 0.944 ! regulation of actin filament polymerization GO:0030833 87 83 0.000 1.000 1.000 1.000 1.000 0.945 ! regulation of actin filament depolymerization GO:0030834 36 32 0.000 1.000 1.000 1.000 1.000 0.704 ! negative regulation of actin filament depolymerization GO:0030835 31 27 0.000 1.000 1.000 1.000 1.000 0.627 ! negative regulation of actin filament polymerization GO:0030837 38 34 0.000 1.000 1.000 1.000 1.000 0.706 ! positive regulation of actin filament polymerization GO:0030838 38 38 0.000 1.000 1.000 1.000 1.000 0.768 ! prostate gland development GO:0030850 41 41 0.000 1.000 1.000 1.000 1.000 0.848 ! regulation of epithelial cell differentiation GO:0030856 62 62 0.000 1.000 1.000 1.000 1.000 0.897 ! positive regulation of epithelial cell differentiation GO:0030858 27 27 0.000 1.000 1.000 1.000 1.000 0.851 ! cortical cytoskeleton organization GO:0030865 23 22 0.000 1.000 1.000 1.000 1.000 0.517 ! regulation of B cell proliferation GO:0030888 57 56 0.000 1.000 1.000 1.000 1.000 0.883 ! positive regulation of B cell proliferation GO:0030890 39 39 0.000 1.000 1.000 1.000 1.000 0.858 ! midbrain development GO:0030901 31 31 0.000 1.000 1.000 1.000 1.000 0.702 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 25 25 0.000 1.000 1.000 1.000 1.000 0.796 ! endoplasmic reticulum unfolded protein response GO:0030968 29 28 0.000 1.000 1.000 1.000 1.000 0.698 ! pancreas development GO:0031016 61 61 0.000 1.000 1.000 1.000 1.000 0.871 ! endocrine pancreas development GO:0031018 37 37 0.000 1.000 1.000 1.000 1.000 0.805 ! actomyosin structure organization GO:0031032 47 46 0.000 1.000 1.000 1.000 1.000 0.749 ! gene silencing by RNA GO:0031047 71 65 0.000 1.000 1.000 1.000 1.000 0.745 ! hair follicle morphogenesis GO:0031069 27 27 0.000 1.000 1.000 1.000 1.000 0.783 ! stress-activated protein kinase signaling cascade GO:0031098 68 68 0.000 1.000 1.000 1.000 1.000 0.856 ! regeneration GO:0031099 51 51 0.000 1.000 1.000 1.000 1.000 0.857 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 48 0.000 1.000 1.000 1.000 1.000 0.799 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 32 29 0.000 1.000 1.000 1.000 1.000 0.702 ! regulation of microtubule polymerization GO:0031113 24 23 0.000 1.000 1.000 1.000 1.000 0.758 ! regulation of microtubule depolymerization GO:0031114 25 22 0.000 1.000 1.000 1.000 1.000 0.595 ! RNA 3'-end processing GO:0031123 47 46 0.000 1.000 1.000 1.000 1.000 0.770 ! mRNA 3'-end processing GO:0031124 33 33 0.000 1.000 1.000 1.000 1.000 0.676 ! biomineral tissue development GO:0031214 60 59 0.000 1.000 1.000 1.000 1.000 0.750 ! regulation of cyclase activity GO:0031279 102 102 0.000 1.000 1.000 1.000 1.000 0.987 ! negative regulation of cyclase activity GO:0031280 42 42 0.000 1.000 1.000 1.000 1.000 0.834 ! positive regulation of cyclase activity GO:0031281 64 64 0.000 1.000 1.000 1.000 1.000 0.882 ! negative regulation of cellular catabolic process GO:0031330 54 53 0.000 1.000 1.000 1.000 1.000 0.850 ! positive regulation of cellular catabolic process GO:0031331 102 101 0.000 1.000 1.000 1.000 1.000 0.985 ! negative regulation of protein complex assembly GO:0031333 71 67 0.000 1.000 1.000 1.000 1.000 0.862 ! positive regulation of protein complex assembly GO:0031334 102 99 0.000 1.000 1.000 1.000 1.000 0.987 ! regulation of cell killing GO:0031341 51 51 0.000 1.000 1.000 1.000 1.000 0.886 ! positive regulation of cell killing GO:0031343 41 41 0.000 1.000 1.000 1.000 1.000 0.878 ! negative regulation of cell projection organization GO:0031345 77 77 0.000 1.000 1.000 1.000 1.000 0.884 ! positive regulation of cell projection organization GO:0031346 179 174 0.000 1.000 1.000 1.000 1.000 0.979 ! negative regulation of defense response GO:0031348 99 97 0.000 1.000 1.000 1.000 1.000 0.993 ! positive regulation of defense response GO:0031349 143 142 0.000 1.000 1.000 1.000 1.000 0.999 ! regulation of protein ubiquitination GO:0031396 114 111 0.000 1.000 1.000 1.000 1.000 0.957 ! negative regulation of protein ubiquitination GO:0031397 37 35 0.000 1.000 1.000 1.000 1.000 0.805 ! positive regulation of protein ubiquitination GO:0031398 67 66 0.000 1.000 1.000 1.000 1.000 0.845 ! keratinization GO:0031424 31 31 0.000 1.000 1.000 1.000 1.000 0.0293 ! actin cytoskeleton reorganization GO:0031532 41 40 0.000 1.000 1.000 1.000 1.000 0.758 ! DNA integrity checkpoint GO:0031570 83 79 0.000 1.000 1.000 1.000 1.000 0.853 ! mitotic cell cycle G1/S transition DNA damage checkpoint GO:0031571 21 21 0.000 1.000 1.000 1.000 1.000 0.718 ! G2/M transition DNA damage checkpoint GO:0031572 31 30 0.000 1.000 1.000 1.000 1.000 0.676 ! mitotic cell cycle G1/S transition checkpoint GO:0031575 30 30 0.000 1.000 1.000 1.000 1.000 0.785 ! cell-substrate adhesion GO:0031589 112 109 0.000 1.000 1.000 1.000 1.000 0.945 ! receptor internalization GO:0031623 42 41 0.000 1.000 1.000 1.000 1.000 0.853 ! regulation of myelination GO:0031641 30 27 0.000 1.000 1.000 1.000 1.000 0.742 ! negative regulation of neurological system process GO:0031645 46 46 0.000 1.000 1.000 1.000 1.000 0.872 ! positive regulation of neurological system process GO:0031646 84 81 0.000 1.000 1.000 1.000 1.000 0.901 ! protein destabilization GO:0031648 20 20 0.000 1.000 1.000 1.000 1.000 0.695 ! lipopolysaccharide-mediated signaling pathway GO:0031663 27 27 0.000 1.000 1.000 1.000 1.000 0.847 ! regulation of protein autophosphorylation GO:0031952 28 27 0.000 1.000 1.000 1.000 1.000 0.780 ! response to corticosteroid stimulus GO:0031960 49 49 0.000 1.000 1.000 1.000 1.000 0.866 ! regulation of TOR signaling cascade GO:0032006 40 37 0.000 1.000 1.000 1.000 1.000 0.715 ! regulation of ARF protein signal transduction GO:0032012 36 36 0.000 1.000 1.000 1.000 1.000 0.0831 ! positive regulation of insulin secretion GO:0032024 51 50 0.000 1.000 1.000 1.000 1.000 0.861 ! negative regulation of protein binding GO:0032091 35 35 0.000 1.000 1.000 1.000 1.000 0.851 ! positive regulation of protein binding GO:0032092 47 46 0.000 1.000 1.000 1.000 1.000 0.814 ! negative regulation of response to external stimulus GO:0032102 129 127 0.000 1.000 1.000 1.000 1.000 0.998 ! positive regulation of response to external stimulus GO:0032103 158 156 0.000 1.000 1.000 1.000 1.000 1.00 ! activation of protein kinase activity GO:0032147 201 200 0.000 1.000 1.000 1.000 1.000 0.972 ! regulation of synaptic transmission, GABAergic GO:0032228 24 24 0.000 1.000 1.000 1.000 1.000 0.821 ! regulation of actin filament bundle assembly GO:0032231 48 47 0.000 1.000 1.000 1.000 1.000 0.833 ! positive regulation of actin filament bundle assembly GO:0032233 30 29 0.000 1.000 1.000 1.000 1.000 0.757 ! regulation of protein polymerization GO:0032271 113 108 0.000 1.000 1.000 1.000 1.000 0.953 ! negative regulation of protein polymerization GO:0032272 48 44 0.000 1.000 1.000 1.000 1.000 0.780 ! positive regulation of protein polymerization GO:0032273 54 53 0.000 1.000 1.000 1.000 1.000 0.834 ! regulation of ARF GTPase activity GO:0032312 22 22 0.000 1.000 1.000 1.000 1.000 0.0881 ! regulation of Rab GTPase activity GO:0032313 38 38 0.000 1.000 1.000 1.000 1.000 0.0112 GO:0032483|regulation of Rab protein signal transduction, ! regulation of Ras GTPase activity GO:0032318 164 164 0.000 1.000 1.000 1.000 1.000 0.921 ! regulation of Rho GTPase activity GO:0032319 80 80 0.000 1.000 1.000 1.000 1.000 0.870 ! positive regulation of Ras GTPase activity GO:0032320 88 88 0.000 1.000 1.000 1.000 1.000 0.955 ! positive regulation of Rho GTPase activity GO:0032321 57 57 0.000 1.000 1.000 1.000 1.000 0.835 ! regulation of chondrocyte differentiation GO:0032330 34 34 0.000 1.000 1.000 1.000 1.000 0.803 ! regulation of hormone metabolic process GO:0032350 29 29 0.000 1.000 1.000 1.000 1.000 0.860 ! response to estradiol stimulus GO:0032355 35 35 0.000 1.000 1.000 1.000 1.000 0.645 ! regulation of lipid transport GO:0032368 61 60 0.000 1.000 1.000 1.000 1.000 0.901 ! negative regulation of lipid transport GO:0032369 22 22 0.000 1.000 1.000 1.000 1.000 0.853 ! positive regulation of lipid transport GO:0032370 31 31 0.000 1.000 1.000 1.000 1.000 0.869 ! regulation of sterol transport GO:0032371 30 29 0.000 1.000 1.000 1.000 1.000 0.875 GO:0032374|regulation of cholesterol transport, ! regulation of cholesterol transport GO:0032374 30 29 0.000 1.000 1.000 1.000 1.000 0.875 GO:0032371|regulation of sterol transport, ! regulation of transporter activity GO:0032409 63 61 0.000 1.000 1.000 1.000 1.000 0.887 ! positive regulation of transporter activity GO:0032411 26 24 0.000 1.000 1.000 1.000 1.000 0.777 ! regulation of ion transmembrane transporter activity GO:0032412 49 47 0.000 1.000 1.000 1.000 1.000 0.872 ! positive regulation of ion transmembrane transporter activity GO:0032414 22 20 0.000 1.000 1.000 1.000 1.000 0.764 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 60 59 0.000 1.000 1.000 1.000 1.000 0.843 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 37 37 0.000 1.000 1.000 1.000 1.000 0.788 ! regulation of protein oligomerization GO:0032459 20 20 0.000 1.000 1.000 1.000 1.000 0.750 ! regulation of cytokinesis GO:0032465 28 27 0.000 1.000 1.000 1.000 1.000 0.744 ! regulation of type I interferon production GO:0032479 33 32 0.000 1.000 1.000 1.000 1.000 0.746 ! positive regulation of type I interferon production GO:0032481 22 22 0.000 1.000 1.000 1.000 1.000 0.680 ! regulation of Rab protein signal transduction GO:0032483 38 38 0.000 1.000 1.000 1.000 1.000 0.0112 GO:0032313|regulation of Rab GTPase activity, ! response to lipopolysaccharide GO:0032496 196 193 0.000 1.000 1.000 1.000 1.000 0.940 ! maintenance of protein location in cell GO:0032507 73 71 0.000 1.000 1.000 1.000 1.000 0.863 ! regulation of interferon-beta production GO:0032648 30 29 0.000 1.000 1.000 1.000 1.000 0.720 ! regulation of interferon-gamma production GO:0032649 72 72 0.000 1.000 1.000 1.000 1.000 0.902 ! regulation of interleukin-1 beta production GO:0032651 32 32 0.000 1.000 1.000 1.000 1.000 0.868 ! regulation of interleukin-1 production GO:0032652 36 36 0.000 1.000 1.000 1.000 1.000 0.880 ! regulation of interleukin-10 production GO:0032653 27 27 0.000 1.000 1.000 1.000 1.000 0.842 ! regulation of interleukin-12 production GO:0032655 40 40 0.000 1.000 1.000 1.000 1.000 0.867 ! regulation of interleukin-2 production GO:0032663 40 40 0.000 1.000 1.000 1.000 1.000 0.868 ! regulation of interleukin-4 production GO:0032673 23 23 0.000 1.000 1.000 1.000 1.000 0.821 ! regulation of interleukin-6 production GO:0032675 81 80 0.000 1.000 1.000 1.000 1.000 0.899 ! regulation of tumor necrosis factor production GO:0032680 77 75 0.000 1.000 1.000 1.000 1.000 0.901 ! negative regulation of interferon-gamma production GO:0032689 23 23 0.000 1.000 1.000 1.000 1.000 0.855 ! negative regulation of interleukin-6 production GO:0032715 22 21 0.000 1.000 1.000 1.000 1.000 0.769 ! negative regulation of tumor necrosis factor production GO:0032720 32 30 0.000 1.000 1.000 1.000 1.000 0.836 ! positive regulation of chemokine production GO:0032722 30 30 0.000 1.000 1.000 1.000 1.000 0.885 ! positive regulation of interferon-gamma production GO:0032729 38 38 0.000 1.000 1.000 1.000 1.000 0.872 ! positive regulation of interleukin-1 beta production GO:0032731 20 20 0.000 1.000 1.000 1.000 1.000 0.825 ! positive regulation of interleukin-1 production GO:0032732 22 22 0.000 1.000 1.000 1.000 1.000 0.840 ! positive regulation of interleukin-12 production GO:0032735 21 21 0.000 1.000 1.000 1.000 1.000 0.857 ! positive regulation of interleukin-6 production GO:0032755 40 40 0.000 1.000 1.000 1.000 1.000 0.848 ! positive regulation of interleukin-8 production GO:0032757 20 20 0.000 1.000 1.000 1.000 1.000 0.799 ! positive regulation of tumor necrosis factor production GO:0032760 35 35 0.000 1.000 1.000 1.000 1.000 0.883 ! regulation of monooxygenase activity GO:0032768 31 31 0.000 1.000 1.000 1.000 1.000 0.872 ! regulation of transcription elongation, DNA-dependent GO:0032784 37 32 0.000 1.000 1.000 1.000 1.000 0.636 ! regulation of natural killer cell activation GO:0032814 28 27 0.000 1.000 1.000 1.000 1.000 0.795 ! positive regulation of natural killer cell activation GO:0032816 21 20 0.000 1.000 1.000 1.000 1.000 0.775 ! glomerulus development GO:0032835 31 31 0.000 1.000 1.000 1.000 1.000 0.836 ! negative regulation of homeostatic process GO:0032845 26 26 0.000 1.000 1.000 1.000 1.000 0.844 ! positive regulation of homeostatic process GO:0032846 70 70 0.000 1.000 1.000 1.000 1.000 0.898 ! positive regulation of Rac GTPase activity GO:0032855 26 26 0.000 1.000 1.000 1.000 1.000 0.713 ! activation of Ras GTPase activity GO:0032856 27 27 0.000 1.000 1.000 1.000 1.000 0.777 ! regulation of stress-activated MAPK cascade GO:0032872 142 142 0.000 1.000 1.000 1.000 1.000 0.985 ! negative regulation of stress-activated MAPK cascade GO:0032873 24 24 0.000 1.000 1.000 1.000 1.000 0.707 GO:0070303|negative regulation of stress-activated protein kinase signaling cascade, ! positive regulation of stress-activated MAPK cascade GO:0032874 57 57 0.000 1.000 1.000 1.000 1.000 0.864 ! regulation of polysaccharide metabolic process GO:0032881 33 33 0.000 1.000 1.000 1.000 1.000 0.842 ! regulation of polysaccharide biosynthetic process GO:0032885 31 31 0.000 1.000 1.000 1.000 1.000 0.831 ! regulation of microtubule-based process GO:0032886 109 103 0.000 1.000 1.000 1.000 1.000 0.962 ! regulation of organic acid transport GO:0032890 37 37 0.000 1.000 1.000 1.000 1.000 0.873 ! positive regulation of organic acid transport GO:0032892 21 21 0.000 1.000 1.000 1.000 1.000 0.810 ! regulation of activin receptor signaling pathway GO:0032925 23 23 0.000 1.000 1.000 1.000 1.000 0.778 ! mononuclear cell proliferation GO:0032943 53 53 0.000 1.000 1.000 1.000 1.000 0.839 ! regulation of mononuclear cell proliferation GO:0032944 159 157 0.000 1.000 1.000 1.000 1.000 0.996 ! negative regulation of mononuclear cell proliferation GO:0032945 55 55 0.000 1.000 1.000 1.000 1.000 0.868 GO:0050672|negative regulation of lymphocyte proliferation, ! positive regulation of mononuclear cell proliferation GO:0032946 102 101 0.000 1.000 1.000 1.000 1.000 0.904 ! regulation of actin cytoskeleton organization GO:0032956 180 175 0.000 1.000 1.000 1.000 1.000 0.960 ! collagen metabolic process GO:0032963 32 32 0.000 1.000 1.000 1.000 1.000 0.553 ! regulation of collagen biosynthetic process GO:0032965 26 25 0.000 1.000 1.000 1.000 1.000 0.846 ! positive regulation of collagen biosynthetic process GO:0032967 22 21 0.000 1.000 1.000 1.000 1.000 0.822 ! regulation of mast cell activation GO:0033003 28 27 0.000 1.000 1.000 1.000 1.000 0.837 ! regulation of mast cell activation involved in immune response GO:0033006 20 20 0.000 1.000 1.000 1.000 1.000 0.817 ! tetrapyrrole metabolic process GO:0033013 42 39 0.000 1.000 1.000 1.000 1.000 0.789 GO:0006778|porphyrin-containing compound metabolic process, ! tetrapyrrole biosynthetic process GO:0033014 27 24 0.000 1.000 1.000 1.000 1.000 0.709 GO:0006779|porphyrin-containing compound biosynthetic process, ! multicellular organismal reproductive behavior GO:0033057 21 21 0.000 1.000 1.000 1.000 1.000 0.774 ! cellular pigmentation GO:0033059 25 22 0.000 1.000 1.000 1.000 1.000 0.778 ! T cell differentiation in thymus GO:0033077 52 52 0.000 1.000 1.000 1.000 1.000 0.863 ! regulation of T cell differentiation in thymus GO:0033081 20 20 0.000 1.000 1.000 1.000 1.000 0.745 ! mitochondrial respiratory chain complex assembly GO:0033108 27 21 0.000 1.000 1.000 1.000 1.000 0.489 ! regulation of peptidyl-serine phosphorylation GO:0033135 68 67 0.000 1.000 1.000 1.000 1.000 0.893 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 54 54 0.000 1.000 1.000 1.000 1.000 0.878 ! regulation of intracellular estrogen receptor signaling pathway GO:0033146 20 20 0.000 1.000 1.000 1.000 1.000 0.676 ! cell cycle cytokinesis GO:0033205 24 23 0.000 1.000 1.000 1.000 1.000 0.674 ! tumor necrosis factor-mediated signaling pathway GO:0033209 21 20 0.000 1.000 1.000 1.000 1.000 0.692 ! regulation of cellular amine metabolic process GO:0033238 27 27 0.000 1.000 1.000 1.000 1.000 0.865 ! cholesterol efflux GO:0033344 23 23 0.000 1.000 1.000 1.000 1.000 0.782 ! carbohydrate homeostasis GO:0033500 109 108 0.000 1.000 1.000 1.000 1.000 0.972 GO:0042593|glucose homeostasis, ! multicellular organismal response to stress GO:0033555 56 56 0.000 1.000 1.000 1.000 1.000 0.881 ! unsaturated fatty acid metabolic process GO:0033559 62 61 0.000 1.000 1.000 1.000 1.000 0.861 ! membrane protein proteolysis GO:0033619 25 23 0.000 1.000 1.000 1.000 1.000 0.696 ! regulation of cell adhesion mediated by integrin GO:0033628 37 34 0.000 1.000 1.000 1.000 1.000 0.859 ! negative regulation of kinase activity GO:0033673 153 151 0.000 1.000 1.000 1.000 1.000 0.966 ! cellular polysaccharide biosynthetic process GO:0033692 27 27 0.000 1.000 1.000 1.000 1.000 0.748 ! response to lipid GO:0033993 40 40 0.000 1.000 1.000 1.000 1.000 0.888 ! regulation of tissue remodeling GO:0034103 46 46 0.000 1.000 1.000 1.000 1.000 0.880 ! positive regulation of tissue remodeling GO:0034105 21 21 0.000 1.000 1.000 1.000 1.000 0.800 ! homotypic cell-cell adhesion GO:0034109 31 30 0.000 1.000 1.000 1.000 1.000 0.774 ! regulation of toll-like receptor signaling pathway GO:0034121 29 28 0.000 1.000 1.000 1.000 1.000 0.811 ! regulation of transcription elongation from RNA polymerase II promoter GO:0034243 24 20 0.000 1.000 1.000 1.000 1.000 0.710 ! response to monosaccharide stimulus GO:0034284 70 70 0.000 1.000 1.000 1.000 1.000 0.874 ! diol metabolic process GO:0034311 36 36 0.000 1.000 1.000 1.000 1.000 0.855 GO:0009712|catechol-containing compound metabolic process, GO:0006584|catecholamine metabolic process, ! cell junction assembly GO:0034329 63 62 0.000 1.000 1.000 1.000 1.000 0.862 ! cell junction organization GO:0034330 94 93 0.000 1.000 1.000 1.000 1.000 0.977 ! response to interferon-gamma GO:0034341 47 47 0.000 1.000 1.000 1.000 1.000 0.823 ! lipid oxidation GO:0034440 52 52 0.000 1.000 1.000 1.000 1.000 0.852 ! substrate adhesion-dependent cell spreading GO:0034446 27 26 0.000 1.000 1.000 1.000 1.000 0.731 ! microtubule anchoring GO:0034453 28 27 0.000 1.000 1.000 1.000 1.000 0.716 ! ncRNA processing GO:0034470 208 200 0.000 1.000 1.000 1.000 1.000 0.723 ! protein localization to chromosome GO:0034502 23 22 0.000 1.000 1.000 1.000 1.000 0.743 ! response to tumor necrosis factor GO:0034612 60 58 0.000 1.000 1.000 1.000 1.000 0.875 ! cellular response to reactive oxygen species GO:0034614 54 54 0.000 1.000 1.000 1.000 1.000 0.861 ! cellular response to unfolded protein GO:0034620 30 29 0.000 1.000 1.000 1.000 1.000 0.707 ! cellular carbohydrate biosynthetic process GO:0034637 75 75 0.000 1.000 1.000 1.000 1.000 0.887 ! cellular hormone metabolic process GO:0034754 86 86 0.000 1.000 1.000 1.000 1.000 0.890 ! histone lysine methylation GO:0034968 47 47 0.000 1.000 1.000 1.000 1.000 0.760 ! response to endoplasmic reticulum stress GO:0034976 54 51 0.000 1.000 1.000 1.000 1.000 0.794 ! somatic stem cell maintenance GO:0035019 44 43 0.000 1.000 1.000 1.000 1.000 0.845 ! regulation of Rho protein signal transduction GO:0035023 155 153 0.000 1.000 1.000 1.000 1.000 0.924 ! sperm-egg recognition GO:0035036 33 33 0.000 1.000 1.000 1.000 1.000 0.412 ! embryonic heart tube development GO:0035050 63 63 0.000 1.000 1.000 1.000 1.000 0.896 ! cardiac cell differentiation GO:0035051 92 91 0.000 1.000 1.000 1.000 1.000 0.902 ! response to nicotine GO:0035094 21 21 0.000 1.000 1.000 1.000 1.000 0.772 ! embryonic forelimb morphogenesis GO:0035115 28 28 0.000 1.000 1.000 1.000 1.000 0.770 ! regulation of tube size GO:0035150 68 68 0.000 1.000 1.000 1.000 1.000 0.900 ! embryonic hemopoiesis GO:0035162 28 27 0.000 1.000 1.000 1.000 1.000 0.774 ! social behavior GO:0035176 28 28 0.000 1.000 1.000 1.000 1.000 0.822 ! posttranscriptional gene silencing by RNA GO:0035194 54 49 0.000 1.000 1.000 1.000 1.000 0.678 ! gene silencing by miRNA GO:0035195 50 45 0.000 1.000 1.000 1.000 1.000 0.629 ! ionotropic glutamate receptor signaling pathway GO:0035235 23 23 0.000 1.000 1.000 1.000 1.000 0.751 ! synaptic transmission, glutamatergic GO:0035249 26 26 0.000 1.000 1.000 1.000 1.000 0.761 ! multicellular organism growth GO:0035264 76 74 0.000 1.000 1.000 1.000 1.000 0.835 ! organ growth GO:0035265 44 42 0.000 1.000 1.000 1.000 1.000 0.867 ! exocrine system development GO:0035272 40 40 0.000 1.000 1.000 1.000 1.000 0.851 ! segmentation GO:0035282 74 74 0.000 1.000 1.000 1.000 1.000 0.891 ! regulation of dephosphorylation GO:0035303 121 116 0.000 1.000 1.000 1.000 1.000 0.773 ! peptidyl-tyrosine dephosphorylation GO:0035335 41 41 0.000 1.000 1.000 1.000 1.000 0.541 ! thioester metabolic process GO:0035383 33 33 0.000 1.000 1.000 1.000 1.000 0.704 GO:0006637|acyl-CoA metabolic process, ! non-canonical Wnt receptor signaling pathway GO:0035567 31 31 0.000 1.000 1.000 1.000 1.000 0.852 ! purinergic receptor signaling pathway GO:0035587 31 31 0.000 1.000 1.000 1.000 1.000 0.657 ! G-protein coupled purinergic receptor signaling pathway GO:0035588 27 27 0.000 1.000 1.000 1.000 1.000 0.562 ! G-protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 21 21 0.000 1.000 1.000 1.000 1.000 0.328 GO:0001608|G-protein coupled nucleotide receptor activity, GO:0045028|G-protein coupled purinergic nucleotide receptor activity, ! purinergic nucleotide receptor signaling pathway GO:0035590 25 25 0.000 1.000 1.000 1.000 1.000 0.507 ! cellular response to drug GO:0035690 24 24 0.000 1.000 1.000 1.000 1.000 0.802 ! CD4-positive, alpha-beta T cell activation GO:0035710 23 23 0.000 1.000 1.000 1.000 1.000 0.808 ! sodium ion transmembrane transport GO:0035725 68 63 0.000 1.000 1.000 1.000 1.000 0.828 ! aorta development GO:0035904 23 22 0.000 1.000 1.000 1.000 1.000 0.827 GO:0035909|aorta morphogenesis, ! aorta morphogenesis GO:0035909 23 22 0.000 1.000 1.000 1.000 1.000 0.827 GO:0035904|aorta development, ! response to topologically incorrect protein GO:0035966 69 67 0.000 1.000 1.000 1.000 1.000 0.740 ! cellular response to topologically incorrect protein GO:0035967 35 34 0.000 1.000 1.000 1.000 1.000 0.744 ! replacement ossification GO:0036075 22 22 0.000 1.000 1.000 1.000 1.000 0.683 GO:0001958|endochondral ossification, ! termination of G-protein coupled receptor signaling pathway GO:0038032 33 33 0.000 1.000 1.000 1.000 1.000 0.129 ! regulation of meiosis GO:0040020 24 24 0.000 1.000 1.000 1.000 1.000 0.725 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 25 25 0.000 1.000 1.000 1.000 1.000 0.788 ! fluid transport GO:0042044 20 20 0.000 1.000 1.000 1.000 1.000 0.741 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 37 37 0.000 1.000 1.000 1.000 1.000 0.816 ! wound healing GO:0042060 188 185 0.000 1.000 1.000 1.000 1.000 0.948 ! T cell proliferation GO:0042098 35 35 0.000 1.000 1.000 1.000 1.000 0.768 ! positive regulation of T cell proliferation GO:0042102 68 67 0.000 1.000 1.000 1.000 1.000 0.899 ! positive regulation of cytokine biosynthetic process GO:0042108 58 58 0.000 1.000 1.000 1.000 1.000 0.894 ! T cell activation GO:0042110 177 177 0.000 1.000 1.000 1.000 1.000 0.971 ! macrophage activation GO:0042116 25 25 0.000 1.000 1.000 1.000 1.000 0.836 ! regulation of T cell proliferation GO:0042129 111 110 0.000 1.000 1.000 1.000 1.000 0.997 ! negative regulation of T cell proliferation GO:0042130 44 44 0.000 1.000 1.000 1.000 1.000 0.850 ! neurotransmitter metabolic process GO:0042133 22 22 0.000 1.000 1.000 1.000 1.000 0.710 ! retrograde transport, endosome to Golgi GO:0042147 27 25 0.000 1.000 1.000 1.000 1.000 0.259 ! lipoprotein metabolic process GO:0042157 78 77 0.000 1.000 1.000 1.000 1.000 0.786 ! lipoprotein biosynthetic process GO:0042158 62 61 0.000 1.000 1.000 1.000 1.000 0.680 ! heme metabolic process GO:0042168 28 27 0.000 1.000 1.000 1.000 1.000 0.720 ! negative regulation of protein catabolic process GO:0042177 41 40 0.000 1.000 1.000 1.000 1.000 0.813 ! response to cocaine GO:0042220 23 23 0.000 1.000 1.000 1.000 1.000 0.842 GO:0014073|response to tropane, ! tissue regeneration GO:0042246 20 20 0.000 1.000 1.000 1.000 1.000 0.612 ! ribosome biogenesis GO:0042254 159 157 0.000 1.000 1.000 1.000 1.000 0.652 ! ribosome assembly GO:0042255 22 22 0.000 1.000 1.000 1.000 1.000 0.484 ! regulation of natural killer cell mediated cytotoxicity GO:0042269 28 28 0.000 1.000 1.000 1.000 1.000 0.809 GO:0002715|regulation of natural killer cell mediated immunity, ! ribosomal small subunit biogenesis GO:0042274 26 26 0.000 1.000 1.000 1.000 1.000 0.390 ! regulation of fatty acid biosynthetic process GO:0042304 27 27 0.000 1.000 1.000 1.000 1.000 0.836 ! vasoconstriction GO:0042310 25 25 0.000 1.000 1.000 1.000 1.000 0.837 ! vasodilation GO:0042311 31 31 0.000 1.000 1.000 1.000 1.000 0.862 ! regulation of vasodilation GO:0042312 39 39 0.000 1.000 1.000 1.000 1.000 0.873 ! negative regulation of phosphorylation GO:0042326 109 107 0.000 1.000 1.000 1.000 1.000 0.992 ! regulation of NF-kappaB import into nucleus GO:0042345 32 32 0.000 1.000 1.000 1.000 1.000 0.829 ! positive regulation of NF-kappaB import into nucleus GO:0042346 20 20 0.000 1.000 1.000 1.000 1.000 0.805 ! cilium assembly GO:0042384 84 81 0.000 1.000 1.000 1.000 1.000 0.691 ! cellular modified amino acid biosynthetic process GO:0042398 34 34 0.000 1.000 1.000 1.000 1.000 0.736 ! cellular biogenic amine biosynthetic process GO:0042401 39 39 0.000 1.000 1.000 1.000 1.000 0.864 ! dopamine metabolic process GO:0042417 23 23 0.000 1.000 1.000 1.000 1.000 0.821 ! indole-containing compound metabolic process GO:0042430 20 20 0.000 1.000 1.000 1.000 1.000 0.773 GO:0006586|indolalkylamine metabolic process, ! ethanolamine-containing compound metabolic process GO:0042439 35 35 0.000 1.000 1.000 1.000 1.000 0.818 ! pigment metabolic process GO:0042440 50 49 0.000 1.000 1.000 1.000 1.000 0.848 ! hormone metabolic process GO:0042445 132 131 0.000 1.000 1.000 1.000 1.000 0.976 ! hormone biosynthetic process GO:0042446 33 33 0.000 1.000 1.000 1.000 1.000 0.811 ! photoreceptor cell development GO:0042461 42 42 0.000 1.000 1.000 1.000 1.000 0.727 ! eye photoreceptor cell development GO:0042462 33 33 0.000 1.000 1.000 1.000 1.000 0.697 ! inner ear morphogenesis GO:0042472 99 98 0.000 1.000 1.000 1.000 1.000 0.974 ! middle ear morphogenesis GO:0042474 24 24 0.000 1.000 1.000 1.000 1.000 0.709 ! regulation of odontogenesis GO:0042481 22 22 0.000 1.000 1.000 1.000 1.000 0.759 ! mechanoreceptor differentiation GO:0042490 55 55 0.000 1.000 1.000 1.000 1.000 0.856 ! auditory receptor cell differentiation GO:0042491 31 31 0.000 1.000 1.000 1.000 1.000 0.790 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 49 49 0.000 1.000 1.000 1.000 1.000 0.886 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 27 27 0.000 1.000 1.000 1.000 1.000 0.815 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 22 22 0.000 1.000 1.000 1.000 1.000 0.832 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 40 40 0.000 1.000 1.000 1.000 1.000 0.885 ! benzene-containing compound metabolic process GO:0042537 66 65 0.000 1.000 1.000 1.000 1.000 0.890 ! response to hydrogen peroxide GO:0042542 60 60 0.000 1.000 1.000 1.000 1.000 0.874 ! neuron maturation GO:0042551 27 26 0.000 1.000 1.000 1.000 1.000 0.641 ! myelination GO:0042552 87 84 0.000 1.000 1.000 1.000 1.000 0.943 ! pteridine-containing compound metabolic process GO:0042558 32 32 0.000 1.000 1.000 1.000 1.000 0.804 ! pteridine-containing compound biosynthetic process GO:0042559 23 23 0.000 1.000 1.000 1.000 1.000 0.742 ! retinoic acid metabolic process GO:0042573 20 20 0.000 1.000 1.000 1.000 1.000 0.671 ! glucose homeostasis GO:0042593 109 108 0.000 1.000 1.000 1.000 1.000 0.972 GO:0033500|carbohydrate homeostasis, ! response to starvation GO:0042594 73 72 0.000 1.000 1.000 1.000 1.000 0.836 ! fear response GO:0042596 26 26 0.000 1.000 1.000 1.000 1.000 0.770 ! cholesterol homeostasis GO:0042632 49 48 0.000 1.000 1.000 1.000 1.000 0.875 ! ovulation cycle GO:0042698 82 82 0.000 1.000 1.000 1.000 1.000 0.894 ! defense response to bacterium GO:0042742 180 179 0.000 1.000 1.000 1.000 1.000 0.638 ! hydrogen peroxide metabolic process GO:0042743 27 27 0.000 1.000 1.000 1.000 1.000 0.764 ! circadian sleep/wake cycle GO:0042745 21 21 0.000 1.000 1.000 1.000 1.000 0.813 ! eating behavior GO:0042755 31 31 0.000 1.000 1.000 1.000 1.000 0.782 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 27 26 0.000 1.000 1.000 1.000 1.000 0.752 ! defense response to protozoan GO:0042832 24 24 0.000 1.000 1.000 1.000 1.000 0.778 ! regulation of transcription factor import into nucleus GO:0042990 61 61 0.000 1.000 1.000 1.000 1.000 0.884 ! negative regulation of transcription factor import into nucleus GO:0042992 25 25 0.000 1.000 1.000 1.000 1.000 0.783 ! positive regulation of transcription factor import into nucleus GO:0042993 31 31 0.000 1.000 1.000 1.000 1.000 0.842 ! T cell homeostasis GO:0043029 25 25 0.000 1.000 1.000 1.000 1.000 0.837 ! regulation of macrophage activation GO:0043030 22 22 0.000 1.000 1.000 1.000 1.000 0.802 ! amino acid activation GO:0043038 44 43 0.000 1.000 1.000 1.000 1.000 0.806 GO:0043039|tRNA aminoacylation, ! tRNA aminoacylation GO:0043039 44 43 0.000 1.000 1.000 1.000 1.000 0.807 GO:0043038|amino acid activation, ! peptide biosynthetic process GO:0043043 20 20 0.000 1.000 1.000 1.000 1.000 0.620 ! receptor metabolic process GO:0043112 66 65 0.000 1.000 1.000 1.000 1.000 0.885 ! receptor clustering GO:0043113 30 30 0.000 1.000 1.000 1.000 1.000 0.795 ! regulation of vascular permeability GO:0043114 21 21 0.000 1.000 1.000 1.000 1.000 0.803 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 140 138 0.000 1.000 1.000 1.000 1.000 0.942 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 108 106 0.000 1.000 1.000 1.000 1.000 0.938 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 25 0.000 1.000 1.000 1.000 1.000 0.730 ! protein complex disassembly GO:0043241 26 26 0.000 1.000 1.000 1.000 1.000 0.721 ! negative regulation of protein complex disassembly GO:0043242 55 48 0.000 1.000 1.000 1.000 1.000 0.761 ! regulation of protein complex disassembly GO:0043244 68 61 0.000 1.000 1.000 1.000 1.000 0.832 ! regulation of carbohydrate biosynthetic process GO:0043255 59 59 0.000 1.000 1.000 1.000 1.000 0.886 ! regulation of potassium ion transport GO:0043266 31 31 0.000 1.000 1.000 1.000 1.000 0.770 ! positive regulation of ion transport GO:0043270 106 105 0.000 1.000 1.000 1.000 1.000 0.988 ! negative regulation of ion transport GO:0043271 40 40 0.000 1.000 1.000 1.000 1.000 0.866 ! response to alkaloid GO:0043279 63 63 0.000 1.000 1.000 1.000 1.000 0.898 ! positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 98 97 0.000 1.000 1.000 1.000 1.000 0.981 ! regulation of leukocyte degranulation GO:0043300 24 24 0.000 1.000 1.000 1.000 1.000 0.822 ! response to exogenous dsRNA GO:0043330 26 25 0.000 1.000 1.000 1.000 1.000 0.735 ! response to dsRNA GO:0043331 41 39 0.000 1.000 1.000 1.000 1.000 0.818 ! CD4-positive, alpha-beta T cell differentiation GO:0043367 22 22 0.000 1.000 1.000 1.000 1.000 0.796 ! regulation of CD4-positive, alpha-beta T cell differentiation GO:0043370 28 28 0.000 1.000 1.000 1.000 1.000 0.847 ! negative regulation of DNA binding GO:0043392 35 35 0.000 1.000 1.000 1.000 1.000 0.820 ! regulation of protein binding GO:0043393 105 104 0.000 1.000 1.000 1.000 1.000 0.992 ! steroid hormone mediated signaling pathway GO:0043401 52 52 0.000 1.000 1.000 1.000 1.000 0.833 ! positive regulation of MAP kinase activity GO:0043406 155 154 0.000 1.000 1.000 1.000 1.000 0.990 ! negative regulation of MAP kinase activity GO:0043407 57 57 0.000 1.000 1.000 1.000 1.000 0.859 ! positive regulation of MAPK cascade GO:0043410 195 192 0.000 1.000 1.000 1.000 1.000 0.990 ! cellular alkene metabolic process GO:0043449 24 24 0.000 1.000 1.000 1.000 1.000 0.722 ! regulation of ATPase activity GO:0043462 23 23 0.000 1.000 1.000 1.000 1.000 0.708 ! regulation of RNA splicing GO:0043484 66 64 0.000 1.000 1.000 1.000 1.000 0.436 ! protein kinase B signaling cascade GO:0043491 30 30 0.000 1.000 1.000 1.000 1.000 0.823 ! regulation of JUN kinase activity GO:0043506 65 65 0.000 1.000 1.000 1.000 1.000 0.887 ! positive regulation of JUN kinase activity GO:0043507 54 54 0.000 1.000 1.000 1.000 1.000 0.874 ! regulation of DNA damage response, signal transduction by p53 class mediator GO:0043516 25 25 0.000 1.000 1.000 1.000 1.000 0.787 ! positive regulation of neuron apoptosis GO:0043525 49 49 0.000 1.000 1.000 1.000 1.000 0.866 ! blood vessel endothelial cell migration GO:0043534 22 22 0.000 1.000 1.000 1.000 1.000 0.811 ! positive regulation of blood vessel endothelial cell migration GO:0043536 22 22 0.000 1.000 1.000 1.000 1.000 0.803 ! endothelial cell migration GO:0043542 44 44 0.000 1.000 1.000 1.000 1.000 0.845 ! positive regulation of GTPase activity GO:0043547 120 120 0.000 1.000 1.000 1.000 1.000 0.941 ! positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 24 24 0.000 1.000 1.000 1.000 1.000 0.819 ! regulation of respiratory gaseous exchange GO:0043576 20 20 0.000 1.000 1.000 1.000 1.000 0.749 ! skin development GO:0043588 57 57 0.000 1.000 1.000 1.000 1.000 0.834 ! regulation of DNA-dependent transcription in response to stress GO:0043620 22 22 0.000 1.000 1.000 1.000 1.000 0.794 ! cellular protein complex assembly GO:0043623 188 179 0.000 1.000 1.000 1.000 1.000 0.941 ! cellular protein complex disassembly GO:0043624 24 24 0.000 1.000 1.000 1.000 1.000 0.691 ! RNA polyadenylation GO:0043631 24 24 0.000 1.000 1.000 1.000 1.000 0.560 ! inositol phosphate metabolic process GO:0043647 25 25 0.000 1.000 1.000 1.000 1.000 0.762 ! dicarboxylic acid metabolic process GO:0043648 45 45 0.000 1.000 1.000 1.000 1.000 0.844 ! regulation of phosphoprotein phosphatase activity GO:0043666 28 28 0.000 1.000 1.000 1.000 1.000 0.687 ! regulation of multi-organism process GO:0043900 85 82 0.000 1.000 1.000 1.000 1.000 0.900 ! negative regulation of multi-organism process GO:0043901 29 29 0.000 1.000 1.000 1.000 1.000 0.848 ! regulation of symbiosis, encompassing mutualism through parasitism GO:0043903 26 26 0.000 1.000 1.000 1.000 1.000 0.841 ! cellular component maintenance GO:0043954 39 39 0.000 1.000 1.000 1.000 1.000 0.762 ! glucan metabolic process GO:0044042 44 44 0.000 1.000 1.000 1.000 1.000 0.791 GO:0006073|cellular glucan metabolic process, ! regulation of digestive system process GO:0044058 26 26 0.000 1.000 1.000 1.000 1.000 0.860 ! regulation of endocrine process GO:0044060 29 29 0.000 1.000 1.000 1.000 1.000 0.856 ! regulation of excretion GO:0044062 22 22 0.000 1.000 1.000 1.000 1.000 0.832 ! positive regulation of cellular component biogenesis GO:0044089 27 25 0.000 1.000 1.000 1.000 1.000 0.748 ! multicellular organismal metabolic process GO:0044236 39 39 0.000 1.000 1.000 1.000 1.000 0.653 ! cellular lipid catabolic process GO:0044242 98 98 0.000 1.000 1.000 1.000 1.000 0.980 ! multicellular organismal catabolic process GO:0044243 21 21 0.000 1.000 1.000 1.000 1.000 0.322 ! regulation of multicellular organismal metabolic process GO:0044246 36 35 0.000 1.000 1.000 1.000 1.000 0.875 ! positive regulation of multicellular organismal metabolic process GO:0044253 31 30 0.000 1.000 1.000 1.000 1.000 0.858 ! multicellular organismal macromolecule metabolic process GO:0044259 34 34 0.000 1.000 1.000 1.000 1.000 0.587 ! cellular polysaccharide metabolic process GO:0044264 57 57 0.000 1.000 1.000 1.000 1.000 0.831 ! sulfur compound biosynthetic process GO:0044272 58 58 0.000 1.000 1.000 1.000 1.000 0.861 ! cellular carbohydrate catabolic process GO:0044275 79 79 0.000 1.000 1.000 1.000 1.000 0.885 ! cellular response to fibroblast growth factor stimulus GO:0044344 47 47 0.000 1.000 1.000 1.000 1.000 0.826 GO:0071774|response to fibroblast growth factor stimulus, ! glycerolipid biosynthetic process GO:0045017 98 96 0.000 1.000 1.000 1.000 1.000 0.953 ! regulated secretory pathway GO:0045055 26 25 0.000 1.000 1.000 1.000 1.000 0.758 ! T cell selection GO:0045058 27 27 0.000 1.000 1.000 1.000 1.000 0.806 ! thymic T cell selection GO:0045061 21 21 0.000 1.000 1.000 1.000 1.000 0.771 ! negative regulation of viral genome replication GO:0045071 24 24 0.000 1.000 1.000 1.000 1.000 0.692 ! regulation of innate immune response GO:0045088 119 117 0.000 1.000 1.000 1.000 1.000 0.992 ! positive regulation of innate immune response GO:0045089 82 81 0.000 1.000 1.000 1.000 1.000 0.896 ! intermediate filament-based process GO:0045103 32 31 0.000 1.000 1.000 1.000 1.000 0.569 ! intermediate filament cytoskeleton organization GO:0045104 31 30 0.000 1.000 1.000 1.000 1.000 0.582 ! intermediate filament organization GO:0045109 20 20 0.000 1.000 1.000 1.000 1.000 0.440 ! regulation of bone resorption GO:0045124 30 30 0.000 1.000 1.000 1.000 1.000 0.825 ! development of primary sexual characteristics GO:0045137 176 175 0.000 1.000 1.000 1.000 1.000 0.982 ! maintenance of protein location GO:0045185 85 83 0.000 1.000 1.000 1.000 1.000 0.878 ! regulation of isotype switching GO:0045191 20 20 0.000 1.000 1.000 1.000 1.000 0.751 ! sarcomere organization GO:0045214 22 22 0.000 1.000 1.000 1.000 1.000 0.702 ! cell-cell junction organization GO:0045216 64 64 0.000 1.000 1.000 1.000 1.000 0.872 ! cellular respiration GO:0045333 74 73 0.000 1.000 1.000 1.000 1.000 0.834 ! regulation of nitric oxide biosynthetic process GO:0045428 44 44 0.000 1.000 1.000 1.000 1.000 0.888 ! positive regulation of nitric oxide biosynthetic process GO:0045429 32 32 0.000 1.000 1.000 1.000 1.000 0.871 ! endothelial cell differentiation GO:0045446 39 39 0.000 1.000 1.000 1.000 1.000 0.838 ! bone resorption GO:0045453 21 21 0.000 1.000 1.000 1.000 1.000 0.693 ! cell redox homeostasis GO:0045454 57 55 0.000 1.000 1.000 1.000 1.000 0.504 ! response to ethanol GO:0045471 47 47 0.000 1.000 1.000 1.000 1.000 0.869 ! photoreceptor cell maintenance GO:0045494 25 25 0.000 1.000 1.000 1.000 1.000 0.654 ! mast cell activation GO:0045576 23 22 0.000 1.000 1.000 1.000 1.000 0.661 ! regulation of B cell differentiation GO:0045577 22 22 0.000 1.000 1.000 1.000 1.000 0.748 ! regulation of T cell differentiation GO:0045580 84 84 0.000 1.000 1.000 1.000 1.000 0.899 ! negative regulation of T cell differentiation GO:0045581 23 23 0.000 1.000 1.000 1.000 1.000 0.811 ! positive regulation of T cell differentiation GO:0045582 58 58 0.000 1.000 1.000 1.000 1.000 0.895 ! negative regulation of fat cell differentiation GO:0045599 30 30 0.000 1.000 1.000 1.000 1.000 0.832 ! regulation of epidermal cell differentiation GO:0045604 23 23 0.000 1.000 1.000 1.000 1.000 0.732 ! regulation of lymphocyte differentiation GO:0045619 108 108 0.000 1.000 1.000 1.000 1.000 0.994 ! negative regulation of lymphocyte differentiation GO:0045620 31 31 0.000 1.000 1.000 1.000 1.000 0.846 ! positive regulation of lymphocyte differentiation GO:0045621 67 67 0.000 1.000 1.000 1.000 1.000 0.897 ! regulation of T-helper cell differentiation GO:0045622 20 20 0.000 1.000 1.000 1.000 1.000 0.819 ! negative regulation of myeloid cell differentiation GO:0045638 64 64 0.000 1.000 1.000 1.000 1.000 0.866 ! regulation of erythrocyte differentiation GO:0045646 35 35 0.000 1.000 1.000 1.000 1.000 0.812 ! negative regulation of neuron differentiation GO:0045665 63 63 0.000 1.000 1.000 1.000 1.000 0.851 ! regulation of osteoblast differentiation GO:0045667 112 111 0.000 1.000 1.000 1.000 1.000 0.964 ! negative regulation of osteoblast differentiation GO:0045668 46 46 0.000 1.000 1.000 1.000 1.000 0.763 ! positive regulation of osteoblast differentiation GO:0045669 58 57 0.000 1.000 1.000 1.000 1.000 0.867 ! positive regulation of osteoclast differentiation GO:0045672 20 20 0.000 1.000 1.000 1.000 1.000 0.771 ! regulation of epidermis development GO:0045682 37 37 0.000 1.000 1.000 1.000 1.000 0.827 ! negative regulation of glial cell differentiation GO:0045686 25 25 0.000 1.000 1.000 1.000 1.000 0.806 ! positive regulation of translation GO:0045727 47 46 0.000 1.000 1.000 1.000 1.000 0.769 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 21 20 0.000 1.000 1.000 1.000 1.000 0.691 ! positive regulation of DNA repair GO:0045739 28 27 0.000 1.000 1.000 1.000 1.000 0.749 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 58 57 0.000 1.000 1.000 1.000 1.000 0.704 ! positive regulation of Notch signaling pathway GO:0045747 20 20 0.000 1.000 1.000 1.000 1.000 0.774 ! regulation of adenylate cyclase activity GO:0045761 94 94 0.000 1.000 1.000 1.000 1.000 0.985 ! positive regulation of adenylate cyclase activity GO:0045762 57 57 0.000 1.000 1.000 1.000 1.000 0.869 ! positive regulation of angiogenesis GO:0045766 99 99 0.000 1.000 1.000 1.000 1.000 0.980 ! positive regulation of axon extension GO:0045773 25 24 0.000 1.000 1.000 1.000 1.000 0.737 ! negative regulation of blood pressure GO:0045776 47 47 0.000 1.000 1.000 1.000 1.000 0.889 ! positive regulation of blood pressure GO:0045777 44 44 0.000 1.000 1.000 1.000 1.000 0.872 ! positive regulation of ossification GO:0045778 42 41 0.000 1.000 1.000 1.000 1.000 0.877 ! positive regulation of cell adhesion GO:0045785 133 129 0.000 1.000 1.000 1.000 1.000 0.975 ! negative regulation of cell cycle GO:0045786 189 186 0.000 1.000 1.000 1.000 1.000 0.943 ! negative regulation of endocytosis GO:0045806 25 25 0.000 1.000 1.000 1.000 1.000 0.715 ! positive regulation of endocytosis GO:0045807 84 84 0.000 1.000 1.000 1.000 1.000 0.896 ! negative regulation of heart contraction GO:0045822 21 20 0.000 1.000 1.000 1.000 1.000 0.820 ! positive regulation of heart contraction GO:0045823 26 26 0.000 1.000 1.000 1.000 1.000 0.857 ! negative regulation of lipid metabolic process GO:0045833 51 51 0.000 1.000 1.000 1.000 1.000 0.896 ! negative regulation of mitosis GO:0045839 22 22 0.000 1.000 1.000 1.000 1.000 0.796 GO:0051784|negative regulation of nuclear division, ! positive regulation of mitosis GO:0045840 36 35 0.000 1.000 1.000 1.000 1.000 0.857 GO:0051785|positive regulation of nuclear division, ! negative regulation of striated muscle tissue development GO:0045843 21 21 0.000 1.000 1.000 1.000 1.000 0.733 ! negative regulation of proteolysis GO:0045861 39 38 0.000 1.000 1.000 1.000 1.000 0.780 ! positive regulation of smoothened signaling pathway GO:0045880 20 20 0.000 1.000 1.000 1.000 1.000 0.624 ! positive regulation of vasoconstriction GO:0045907 32 32 0.000 1.000 1.000 1.000 1.000 0.854 ! positive regulation of vasodilation GO:0045909 28 28 0.000 1.000 1.000 1.000 1.000 0.863 ! negative regulation of carbohydrate metabolic process GO:0045912 22 22 0.000 1.000 1.000 1.000 1.000 0.805 ! positive regulation of carbohydrate metabolic process GO:0045913 50 48 0.000 1.000 1.000 1.000 1.000 0.884 ! positive regulation of exocytosis GO:0045921 42 42 0.000 1.000 1.000 1.000 1.000 0.813 ! positive regulation of fatty acid metabolic process GO:0045923 30 30 0.000 1.000 1.000 1.000 1.000 0.855 ! negative regulation of mitotic cell cycle GO:0045930 37 36 0.000 1.000 1.000 1.000 1.000 0.740 ! positive regulation of muscle contraction GO:0045933 30 30 0.000 1.000 1.000 1.000 1.000 0.860 ! negative regulation of phosphate metabolic process GO:0045936 116 114 0.000 1.000 1.000 1.000 1.000 0.990 GO:0010563|negative regulation of phosphorus metabolic process, ! positive regulation of steroid metabolic process GO:0045940 26 26 0.000 1.000 1.000 1.000 1.000 0.855 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 20 20 0.000 1.000 1.000 1.000 1.000 0.758 ! negative regulation of nucleotide metabolic process GO:0045980 56 56 0.000 1.000 1.000 1.000 1.000 0.872 ! positive regulation of nucleotide metabolic process GO:0045981 101 100 0.000 1.000 1.000 1.000 1.000 0.985 ! positive regulation of smooth muscle contraction GO:0045987 24 24 0.000 1.000 1.000 1.000 1.000 0.830 ! regulation of activated T cell proliferation GO:0046006 26 26 0.000 1.000 1.000 1.000 1.000 0.819 ! GTP metabolic process GO:0046039 165 165 0.000 1.000 1.000 1.000 1.000 0.911 ! cAMP metabolic process GO:0046058 28 28 0.000 1.000 1.000 1.000 1.000 0.736 ! cGMP metabolic process GO:0046068 25 25 0.000 1.000 1.000 1.000 1.000 0.712 ! pigment biosynthetic process GO:0046148 38 37 0.000 1.000 1.000 1.000 1.000 0.818 ! alcohol catabolic process GO:0046164 82 82 0.000 1.000 1.000 1.000 1.000 0.893 ! alcohol biosynthetic process GO:0046165 76 76 0.000 1.000 1.000 1.000 1.000 0.897 ! regulation of fatty acid oxidation GO:0046320 21 21 0.000 1.000 1.000 1.000 1.000 0.768 ! regulation of glucose import GO:0046324 51 49 0.000 1.000 1.000 1.000 1.000 0.847 ! positive regulation of glucose import GO:0046326 32 31 0.000 1.000 1.000 1.000 1.000 0.807 ! regulation of JNK cascade GO:0046328 126 126 0.000 1.000 1.000 1.000 1.000 0.984 ! negative regulation of JNK cascade GO:0046329 20 20 0.000 1.000 1.000 1.000 1.000 0.653 ! positive regulation of JNK cascade GO:0046330 50 50 0.000 1.000 1.000 1.000 1.000 0.851 ! acetyl-CoA catabolic process GO:0046356 26 26 0.000 1.000 1.000 1.000 1.000 0.751 ! monosaccharide biosynthetic process GO:0046364 43 43 0.000 1.000 1.000 1.000 1.000 0.841 ! monosaccharide catabolic process GO:0046365 62 62 0.000 1.000 1.000 1.000 1.000 0.862 ! carboxylic acid catabolic process GO:0046395 131 128 0.000 1.000 1.000 1.000 1.000 0.981 GO:0016054|organic acid catabolic process, ! regulation of JAK-STAT cascade GO:0046425 77 77 0.000 1.000 1.000 1.000 1.000 0.897 ! positive regulation of JAK-STAT cascade GO:0046427 53 53 0.000 1.000 1.000 1.000 1.000 0.893 ! organophosphate catabolic process GO:0046434 22 22 0.000 1.000 1.000 1.000 1.000 0.737 ! icosanoid biosynthetic process GO:0046456 39 38 0.000 1.000 1.000 1.000 1.000 0.832 ! membrane lipid biosynthetic process GO:0046467 43 38 0.000 1.000 1.000 1.000 1.000 0.755 ! phosphatidylcholine metabolic process GO:0046470 24 24 0.000 1.000 1.000 1.000 1.000 0.752 ! glycerophospholipid biosynthetic process GO:0046474 84 82 0.000 1.000 1.000 1.000 1.000 0.946 ! phosphatidylinositol metabolic process GO:0046488 101 100 0.000 1.000 1.000 1.000 1.000 0.943 ! nicotinamide nucleotide metabolic process GO:0046496 52 52 0.000 1.000 1.000 1.000 1.000 0.854 ! sphingoid metabolic process GO:0046519 61 57 0.000 1.000 1.000 1.000 1.000 0.829 ! sphingoid biosynthetic process GO:0046520 27 23 0.000 1.000 1.000 1.000 1.000 0.693 ! photoreceptor cell differentiation GO:0046530 52 52 0.000 1.000 1.000 1.000 1.000 0.805 ! development of primary female sexual characteristics GO:0046545 92 92 0.000 1.000 1.000 1.000 1.000 0.985 ! development of primary male sexual characteristics GO:0046546 88 87 0.000 1.000 1.000 1.000 1.000 0.896 ! positive regulation of Ras protein signal transduction GO:0046579 27 27 0.000 1.000 1.000 1.000 1.000 0.777 ! negative regulation of Ras protein signal transduction GO:0046580 34 34 0.000 1.000 1.000 1.000 1.000 0.658 ! regulation of organ growth GO:0046620 76 76 0.000 1.000 1.000 1.000 1.000 0.899 ! negative regulation of insulin receptor signaling pathway GO:0046627 25 25 0.000 1.000 1.000 1.000 1.000 0.783 ! alpha-beta T cell activation GO:0046631 43 43 0.000 1.000 1.000 1.000 1.000 0.867 ! alpha-beta T cell differentiation GO:0046632 36 36 0.000 1.000 1.000 1.000 1.000 0.849 ! regulation of alpha-beta T cell activation GO:0046634 61 61 0.000 1.000 1.000 1.000 1.000 0.898 ! positive regulation of alpha-beta T cell activation GO:0046635 48 48 0.000 1.000 1.000 1.000 1.000 0.892 ! regulation of alpha-beta T cell differentiation GO:0046637 42 42 0.000 1.000 1.000 1.000 1.000 0.883 ! positive regulation of alpha-beta T cell differentiation GO:0046638 33 33 0.000 1.000 1.000 1.000 1.000 0.865 ! regulation of alpha-beta T cell proliferation GO:0046640 20 20 0.000 1.000 1.000 1.000 1.000 0.806 ! lymphocyte proliferation GO:0046651 52 52 0.000 1.000 1.000 1.000 1.000 0.835 ! female sex differentiation GO:0046660 99 99 0.000 1.000 1.000 1.000 1.000 0.989 ! male sex differentiation GO:0046661 95 94 0.000 1.000 1.000 1.000 1.000 0.899 ! negative regulation of insulin secretion GO:0046676 35 35 0.000 1.000 1.000 1.000 1.000 0.809 ! response to antibiotic GO:0046677 25 24 0.000 1.000 1.000 1.000 1.000 0.682 ! response to cadmium ion GO:0046686 20 20 0.000 1.000 1.000 1.000 1.000 0.673 ! acid secretion GO:0046717 24 24 0.000 1.000 1.000 1.000 1.000 0.805 ! lipid phosphorylation GO:0046834 36 36 0.000 1.000 1.000 1.000 1.000 0.775 ! filopodium assembly GO:0046847 24 24 0.000 1.000 1.000 1.000 1.000 0.287 ! regulation of bone remodeling GO:0046850 36 36 0.000 1.000 1.000 1.000 1.000 0.846 ! phosphatidylinositol phosphorylation GO:0046854 31 31 0.000 1.000 1.000 1.000 1.000 0.757 ! hormone secretion GO:0046879 66 65 0.000 1.000 1.000 1.000 1.000 0.879 ! regulation of hormone biosynthetic process GO:0046885 21 21 0.000 1.000 1.000 1.000 1.000 0.829 ! negative regulation of hormone secretion GO:0046888 57 57 0.000 1.000 1.000 1.000 1.000 0.877 ! regulation of neurotransmitter secretion GO:0046928 42 41 0.000 1.000 1.000 1.000 1.000 0.800 ! nucleotide phosphorylation GO:0046939 21 21 0.000 1.000 1.000 1.000 1.000 0.777 ! carboxylic acid transport GO:0046942 171 167 0.000 1.000 1.000 1.000 1.000 0.948 ! antigen processing and presentation of peptide antigen GO:0048002 37 37 0.000 1.000 1.000 1.000 1.000 0.780 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 30 0.000 1.000 1.000 1.000 1.000 0.721 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 24 24 0.000 1.000 1.000 1.000 1.000 0.813 ! ephrin receptor signaling pathway GO:0048013 29 29 0.000 1.000 1.000 1.000 1.000 0.652 ! inositol phosphate-mediated signaling GO:0048016 55 55 0.000 1.000 1.000 1.000 1.000 0.871 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 38 37 0.000 1.000 1.000 1.000 1.000 0.530 ! positive regulation of fibroblast proliferation GO:0048146 43 43 0.000 1.000 1.000 1.000 1.000 0.852 ! regulation of synaptic plasticity GO:0048167 107 106 0.000 1.000 1.000 1.000 1.000 0.986 ! regulation of neuronal synaptic plasticity GO:0048168 51 50 0.000 1.000 1.000 1.000 1.000 0.847 ! regulation of long-term neuronal synaptic plasticity GO:0048169 33 33 0.000 1.000 1.000 1.000 1.000 0.830 ! Golgi vesicle transport GO:0048193 102 101 0.000 1.000 1.000 1.000 1.000 0.774 ! regulation of receptor-mediated endocytosis GO:0048259 39 39 0.000 1.000 1.000 1.000 1.000 0.853 ! positive regulation of receptor-mediated endocytosis GO:0048260 27 27 0.000 1.000 1.000 1.000 1.000 0.825 ! response to pain GO:0048265 29 29 0.000 1.000 1.000 1.000 1.000 0.824 ! vesicle docking GO:0048278 23 22 0.000 1.000 1.000 1.000 1.000 0.599 ! organelle fusion GO:0048284 46 44 0.000 1.000 1.000 1.000 1.000 0.754 ! mesoderm morphogenesis GO:0048332 61 61 0.000 1.000 1.000 1.000 1.000 0.893 ! cell maturation GO:0048469 117 115 0.000 1.000 1.000 1.000 1.000 0.966 ! oogenesis GO:0048477 58 58 0.000 1.000 1.000 1.000 1.000 0.820 ! autonomic nervous system development GO:0048483 44 44 0.000 1.000 1.000 1.000 1.000 0.881 ! sympathetic nervous system development GO:0048485 21 21 0.000 1.000 1.000 1.000 1.000 0.831 ! synaptic vesicle transport GO:0048489 62 58 0.000 1.000 1.000 1.000 1.000 0.829 ! circadian behavior GO:0048512 26 26 0.000 1.000 1.000 1.000 1.000 0.819 ! spermatid differentiation GO:0048515 93 91 0.000 1.000 1.000 1.000 1.000 0.786 ! positive regulation of behavior GO:0048520 98 97 0.000 1.000 1.000 1.000 1.000 0.903 ! negative regulation of behavior GO:0048521 32 32 0.000 1.000 1.000 1.000 1.000 0.875 ! negative regulation of viral reproduction GO:0048525 26 26 0.000 1.000 1.000 1.000 1.000 0.694 ! lymph node development GO:0048535 20 20 0.000 1.000 1.000 1.000 1.000 0.679 ! spleen development GO:0048536 29 29 0.000 1.000 1.000 1.000 1.000 0.758 ! thymus development GO:0048538 34 34 0.000 1.000 1.000 1.000 1.000 0.830 ! digestive tract morphogenesis GO:0048546 52 52 0.000 1.000 1.000 1.000 1.000 0.899 ! embryonic digestive tract morphogenesis GO:0048557 20 20 0.000 1.000 1.000 1.000 1.000 0.856 ! developmental cell growth GO:0048588 32 32 0.000 1.000 1.000 1.000 1.000 0.790 ! oocyte development GO:0048599 28 28 0.000 1.000 1.000 1.000 1.000 0.809 ! negative regulation of muscle organ development GO:0048635 22 22 0.000 1.000 1.000 1.000 1.000 0.748 ! regulation of developmental growth GO:0048638 133 131 0.000 1.000 1.000 1.000 1.000 0.996 ! positive regulation of developmental growth GO:0048639 51 49 0.000 1.000 1.000 1.000 1.000 0.878 ! negative regulation of developmental growth GO:0048640 30 30 0.000 1.000 1.000 1.000 1.000 0.822 ! muscle organ morphogenesis GO:0048644 75 75 0.000 1.000 1.000 1.000 1.000 0.897 ! organ formation GO:0048645 26 26 0.000 1.000 1.000 1.000 1.000 0.821 ! positive regulation of smooth muscle cell proliferation GO:0048661 57 57 0.000 1.000 1.000 1.000 1.000 0.893 ! neuron fate commitment GO:0048663 64 64 0.000 1.000 1.000 1.000 1.000 0.882 ! neuron fate specification GO:0048665 30 30 0.000 1.000 1.000 1.000 1.000 0.780 ! response to axon injury GO:0048678 21 21 0.000 1.000 1.000 1.000 1.000 0.751 ! embryonic cranial skeleton morphogenesis GO:0048701 39 39 0.000 1.000 1.000 1.000 1.000 0.863 ! embryonic skeletal system morphogenesis GO:0048704 90 90 0.000 1.000 1.000 1.000 1.000 0.962 ! skeletal system morphogenesis GO:0048705 191 190 0.000 1.000 1.000 1.000 1.000 0.958 ! astrocyte differentiation GO:0048708 26 26 0.000 1.000 1.000 1.000 1.000 0.832 ! oligodendrocyte differentiation GO:0048709 42 40 0.000 1.000 1.000 1.000 1.000 0.852 ! regulation of astrocyte differentiation GO:0048710 25 25 0.000 1.000 1.000 1.000 1.000 0.829 ! cardiac muscle tissue development GO:0048738 129 128 0.000 1.000 1.000 1.000 1.000 0.996 ! skeletal muscle fiber development GO:0048741 48 48 0.000 1.000 1.000 1.000 1.000 0.838 ! smooth muscle tissue development GO:0048745 24 23 0.000 1.000 1.000 1.000 1.000 0.776 ! muscle fiber development GO:0048747 67 67 0.000 1.000 1.000 1.000 1.000 0.854 ! genitalia development GO:0048806 34 34 0.000 1.000 1.000 1.000 1.000 0.849 ! dendrite morphogenesis GO:0048813 33 33 0.000 1.000 1.000 1.000 1.000 0.776 ! regulation of dendrite morphogenesis GO:0048814 50 49 0.000 1.000 1.000 1.000 1.000 0.858 ! erythrocyte development GO:0048821 28 27 0.000 1.000 1.000 1.000 1.000 0.740 ! inner ear development GO:0048839 168 167 0.000 1.000 1.000 1.000 1.000 0.960 ! artery morphogenesis GO:0048844 49 48 0.000 1.000 1.000 1.000 1.000 0.891 ! brain morphogenesis GO:0048854 30 30 0.000 1.000 1.000 1.000 1.000 0.830 ! chromosome localization GO:0050000 21 20 0.000 1.000 1.000 1.000 1.000 0.691 ! regulation of catecholamine secretion GO:0050433 37 37 0.000 1.000 1.000 1.000 1.000 0.874 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 24 23 0.000 1.000 1.000 1.000 1.000 0.630 ! nucleic acid transport GO:0050657 83 83 0.000 1.000 1.000 1.000 1.000 0.747 GO:0051236|establishment of RNA localization, GO:0050658|RNA transport, ! RNA transport GO:0050658 83 83 0.000 1.000 1.000 1.000 1.000 0.747 GO:0051236|establishment of RNA localization, GO:0050657|nucleic acid transport, ! cytokine secretion GO:0050663 21 21 0.000 1.000 1.000 1.000 1.000 0.765 ! regulation of lymphocyte proliferation GO:0050670 158 156 0.000 1.000 1.000 1.000 1.000 0.995 ! positive regulation of lymphocyte proliferation GO:0050671 101 100 0.000 1.000 1.000 1.000 1.000 0.903 ! negative regulation of lymphocyte proliferation GO:0050672 55 55 0.000 1.000 1.000 1.000 1.000 0.868 GO:0032945|negative regulation of mononuclear cell proliferation, ! epithelial cell proliferation GO:0050673 48 48 0.000 1.000 1.000 1.000 1.000 0.860 ! positive regulation of epithelial cell proliferation GO:0050679 121 121 0.000 1.000 1.000 1.000 1.000 0.996 ! negative regulation of epithelial cell proliferation GO:0050680 84 83 0.000 1.000 1.000 1.000 1.000 0.892 ! regulation of mRNA processing GO:0050684 50 49 0.000 1.000 1.000 1.000 1.000 0.660 ! regulation of defense response to virus GO:0050688 35 33 0.000 1.000 1.000 1.000 1.000 0.795 ! regulation of defense response to virus by host GO:0050691 24 22 0.000 1.000 1.000 1.000 1.000 0.759 ! regulation of cytokine secretion GO:0050707 87 84 0.000 1.000 1.000 1.000 1.000 0.894 ! regulation of protein secretion GO:0050708 135 132 0.000 1.000 1.000 1.000 1.000 0.981 ! negative regulation of protein secretion GO:0050709 41 39 0.000 1.000 1.000 1.000 1.000 0.824 ! negative regulation of cytokine secretion GO:0050710 26 24 0.000 1.000 1.000 1.000 1.000 0.773 ! positive regulation of protein secretion GO:0050714 89 88 0.000 1.000 1.000 1.000 1.000 0.897 ! positive regulation of cytokine secretion GO:0050715 61 60 0.000 1.000 1.000 1.000 1.000 0.878 ! regulation of inflammatory response GO:0050727 185 183 0.000 1.000 1.000 1.000 1.000 0.997 ! negative regulation of inflammatory response GO:0050728 75 73 0.000 1.000 1.000 1.000 1.000 0.893 ! positive regulation of inflammatory response GO:0050729 64 64 0.000 1.000 1.000 1.000 1.000 0.902 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 137 137 0.000 1.000 1.000 1.000 1.000 0.998 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 107 107 0.000 1.000 1.000 1.000 1.000 0.999 ! regulation of phagocytosis GO:0050764 53 53 0.000 1.000 1.000 1.000 1.000 0.876 ! positive regulation of phagocytosis GO:0050766 41 41 0.000 1.000 1.000 1.000 1.000 0.850 ! negative regulation of neurogenesis GO:0050768 91 91 0.000 1.000 1.000 1.000 1.000 0.900 ! regulation of axonogenesis GO:0050770 110 108 0.000 1.000 1.000 1.000 1.000 0.970 ! negative regulation of axonogenesis GO:0050771 38 38 0.000 1.000 1.000 1.000 1.000 0.835 ! positive regulation of axonogenesis GO:0050772 52 50 0.000 1.000 1.000 1.000 1.000 0.836 ! regulation of dendrite development GO:0050773 79 78 0.000 1.000 1.000 1.000 1.000 0.884 ! negative regulation of immune response GO:0050777 65 64 0.000 1.000 1.000 1.000 1.000 0.891 ! regulation of behavior GO:0050795 154 153 0.000 1.000 1.000 1.000 1.000 0.999 ! regulation of insulin secretion GO:0050796 116 115 0.000 1.000 1.000 1.000 1.000 0.980 ! regulation of synapse structure and activity GO:0050803 63 61 0.000 1.000 1.000 1.000 1.000 0.870 ! negative regulation of synaptic transmission GO:0050805 36 36 0.000 1.000 1.000 1.000 1.000 0.846 ! positive regulation of synaptic transmission GO:0050806 70 70 0.000 1.000 1.000 1.000 1.000 0.899 ! regulation of synapse organization GO:0050807 57 55 0.000 1.000 1.000 1.000 1.000 0.864 ! synapse organization GO:0050808 90 89 0.000 1.000 1.000 1.000 1.000 0.964 ! regulation of steroid biosynthetic process GO:0050810 50 50 0.000 1.000 1.000 1.000 1.000 0.880 ! coagulation GO:0050817 96 94 0.000 1.000 1.000 1.000 1.000 0.931 GO:0007596|blood coagulation, ! regulation of coagulation GO:0050818 59 59 0.000 1.000 1.000 1.000 1.000 0.876 ! negative regulation of coagulation GO:0050819 29 29 0.000 1.000 1.000 1.000 1.000 0.715 ! defense response to Gram-negative bacterium GO:0050829 27 27 0.000 1.000 1.000 1.000 1.000 0.515 ! defense response to Gram-positive bacterium GO:0050830 49 49 0.000 1.000 1.000 1.000 1.000 0.831 ! regulation of calcium-mediated signaling GO:0050848 40 38 0.000 1.000 1.000 1.000 1.000 0.798 ! positive regulation of calcium-mediated signaling GO:0050850 26 25 0.000 1.000 1.000 1.000 1.000 0.781 ! antigen receptor-mediated signaling pathway GO:0050851 58 57 0.000 1.000 1.000 1.000 1.000 0.842 ! T cell receptor signaling pathway GO:0050852 33 32 0.000 1.000 1.000 1.000 1.000 0.785 ! B cell receptor signaling pathway GO:0050853 27 27 0.000 1.000 1.000 1.000 1.000 0.703 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 27 27 0.000 1.000 1.000 1.000 1.000 0.784 ! regulation of T cell receptor signaling pathway GO:0050856 21 21 0.000 1.000 1.000 1.000 1.000 0.731 ! regulation of T cell activation GO:0050863 188 187 0.000 1.000 1.000 1.000 1.000 0.990 ! regulation of B cell activation GO:0050864 94 93 0.000 1.000 1.000 1.000 1.000 0.901 ! negative regulation of cell activation GO:0050866 120 119 0.000 1.000 1.000 1.000 1.000 0.991 ! negative regulation of T cell activation GO:0050868 72 72 0.000 1.000 1.000 1.000 1.000 0.882 ! negative regulation of B cell activation GO:0050869 25 25 0.000 1.000 1.000 1.000 1.000 0.808 ! positive regulation of T cell activation GO:0050870 123 122 0.000 1.000 1.000 1.000 1.000 0.998 ! positive regulation of B cell activation GO:0050871 62 62 0.000 1.000 1.000 1.000 1.000 0.896 ! brown fat cell differentiation GO:0050873 29 29 0.000 1.000 1.000 1.000 1.000 0.691 ! multicellular organismal movement GO:0050879 21 21 0.000 1.000 1.000 1.000 1.000 0.685 GO:0050881|musculoskeletal movement, ! regulation of blood vessel size GO:0050880 67 67 0.000 1.000 1.000 1.000 1.000 0.899 ! musculoskeletal movement GO:0050881 21 21 0.000 1.000 1.000 1.000 1.000 0.685 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling balance GO:0050885 54 53 0.000 1.000 1.000 1.000 1.000 0.853 ! endocrine process GO:0050886 41 41 0.000 1.000 1.000 1.000 1.000 0.869 ! cognition GO:0050890 184 183 0.000 1.000 1.000 1.000 1.000 0.982 ! leukocyte migration GO:0050900 109 108 0.000 1.000 1.000 1.000 1.000 0.981 ! neuromuscular process GO:0050905 92 91 0.000 1.000 1.000 1.000 1.000 0.983 ! detection of stimulus involved in sensory perception GO:0050906 78 75 0.000 1.000 1.000 1.000 1.000 0.832 ! detection of chemical stimulus involved in sensory perception GO:0050907 35 33 0.000 1.000 1.000 1.000 1.000 0.394 ! sensory perception of taste GO:0050909 72 72 0.000 1.000 1.000 1.000 1.000 0.00287 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 28 28 0.000 1.000 1.000 1.000 1.000 0.247 ! sensory perception of bitter taste GO:0050913 26 26 0.000 1.000 1.000 1.000 1.000 0.134 ! positive chemotaxis GO:0050918 22 22 0.000 1.000 1.000 1.000 1.000 0.830 ! regulation of chemotaxis GO:0050920 107 106 0.000 1.000 1.000 1.000 1.000 0.999 ! positive regulation of chemotaxis GO:0050921 83 82 0.000 1.000 1.000 1.000 1.000 0.901 ! negative regulation of chemotaxis GO:0050922 20 20 0.000 1.000 1.000 1.000 1.000 0.810 ! regulation of positive chemotaxis GO:0050926 29 28 0.000 1.000 1.000 1.000 1.000 0.796 ! positive regulation of positive chemotaxis GO:0050927 28 27 0.000 1.000 1.000 1.000 1.000 0.794 ! sensory perception of mechanical stimulus GO:0050954 139 134 0.000 1.000 1.000 1.000 1.000 0.940 ! detection of mechanical stimulus involved in sensory perception GO:0050974 30 28 0.000 1.000 1.000 1.000 1.000 0.812 ! detection of mechanical stimulus GO:0050982 37 34 0.000 1.000 1.000 1.000 1.000 0.843 ! regulation of lipid catabolic process GO:0050994 42 42 0.000 1.000 1.000 1.000 1.000 0.879 ! regulation of nitric-oxide synthase activity GO:0050999 21 21 0.000 1.000 1.000 1.000 1.000 0.824 ! regulation of lipoprotein lipase activity GO:0051004 30 30 0.000 1.000 1.000 1.000 1.000 0.831 ! actin filament bundle assembly GO:0051017 32 32 0.000 1.000 1.000 1.000 1.000 0.710 ! mRNA transport GO:0051028 70 70 0.000 1.000 1.000 1.000 1.000 0.673 ! negative regulation of secretion GO:0051048 148 145 0.000 1.000 1.000 1.000 1.000 0.994 ! negative regulation of lipid biosynthetic process GO:0051055 28 28 0.000 1.000 1.000 1.000 1.000 0.859 ! positive regulation of small GTPase mediated signal transduction GO:0051057 32 32 0.000 1.000 1.000 1.000 1.000 0.786 ! negative regulation of small GTPase mediated signal transduction GO:0051058 35 35 0.000 1.000 1.000 1.000 1.000 0.675 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 85 85 0.000 1.000 1.000 1.000 1.000 0.894 ! negative regulation of binding GO:0051100 73 73 0.000 1.000 1.000 1.000 1.000 0.894 ! negative regulation of striated muscle cell differentiation GO:0051154 25 25 0.000 1.000 1.000 1.000 1.000 0.547 ! positive regulation of striated muscle cell differentiation GO:0051155 24 24 0.000 1.000 1.000 1.000 1.000 0.822 ! nuclear export GO:0051168 65 64 0.000 1.000 1.000 1.000 1.000 0.744 ! vitamin transport GO:0051180 21 21 0.000 1.000 1.000 1.000 1.000 0.702 ! cofactor catabolic process GO:0051187 40 40 0.000 1.000 1.000 1.000 1.000 0.841 ! cofactor biosynthetic process GO:0051188 114 111 0.000 1.000 1.000 1.000 1.000 0.963 ! release of sequestered calcium ion into cytosol GO:0051209 34 34 0.000 1.000 1.000 1.000 1.000 0.854 GO:0051283|negative regulation of sequestering of calcium ion, ! cartilage development GO:0051216 131 131 0.000 1.000 1.000 1.000 1.000 0.969 ! maintenance of location GO:0051235 103 101 0.000 1.000 1.000 1.000 1.000 0.976 ! establishment of RNA localization GO:0051236 83 83 0.000 1.000 1.000 1.000 1.000 0.747 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! negative regulation of lymphocyte activation GO:0051250 97 97 0.000 1.000 1.000 1.000 1.000 0.986 ! positive regulation of lymphocyte activation GO:0051251 178 176 0.000 1.000 1.000 1.000 1.000 0.999 ! protein polymerization GO:0051258 45 45 0.000 1.000 1.000 1.000 1.000 0.648 ! protein tetramerization GO:0051262 87 87 0.000 1.000 1.000 1.000 1.000 0.965 ! regulation of release of sequestered calcium ion into cytosol GO:0051279 37 37 0.000 1.000 1.000 1.000 1.000 0.845 ! regulation of sequestering of calcium ion GO:0051282 35 35 0.000 1.000 1.000 1.000 1.000 0.855 ! negative regulation of sequestering of calcium ion GO:0051283 34 34 0.000 1.000 1.000 1.000 1.000 0.854 GO:0051209|release of sequestered calcium ion into cytosol, ! protein homotetramerization GO:0051289 56 56 0.000 1.000 1.000 1.000 1.000 0.838 ! protein heterooligomerization GO:0051291 100 100 0.000 1.000 1.000 1.000 1.000 0.952 ! regulation of cell division GO:0051302 81 79 0.000 1.000 1.000 1.000 1.000 0.880 ! prophase GO:0051324 20 20 0.000 1.000 1.000 1.000 1.000 0.573 GO:0007128|meiotic prophase I, ! regulation of lyase activity GO:0051339 105 105 0.000 1.000 1.000 1.000 1.000 0.988 ! regulation of ligase activity GO:0051340 29 29 0.000 1.000 1.000 1.000 1.000 0.806 ! regulation of oxidoreductase activity GO:0051341 52 52 0.000 1.000 1.000 1.000 1.000 0.893 ! negative regulation of transferase activity GO:0051348 164 162 0.000 1.000 1.000 1.000 1.000 0.969 ! positive regulation of lyase activity GO:0051349 66 66 0.000 1.000 1.000 1.000 1.000 0.884 ! negative regulation of lyase activity GO:0051350 43 43 0.000 1.000 1.000 1.000 1.000 0.838 ! positive regulation of oxidoreductase activity GO:0051353 29 29 0.000 1.000 1.000 1.000 1.000 0.859 ! negative regulation of oxidoreductase activity GO:0051354 21 21 0.000 1.000 1.000 1.000 1.000 0.804 ! response to glucocorticoid stimulus GO:0051384 47 47 0.000 1.000 1.000 1.000 1.000 0.860 ! neuron apoptosis GO:0051402 27 27 0.000 1.000 1.000 1.000 1.000 0.787 ! stress-activated MAPK cascade GO:0051403 64 64 0.000 1.000 1.000 1.000 1.000 0.852 ! regulation of ubiquitin-protein ligase activity GO:0051438 26 26 0.000 1.000 1.000 1.000 1.000 0.793 ! regulation of meiotic cell cycle GO:0051445 28 28 0.000 1.000 1.000 1.000 1.000 0.755 ! regulation of intracellular pH GO:0051453 22 21 0.000 1.000 1.000 1.000 1.000 0.758 ! cytosolic calcium ion homeostasis GO:0051480 185 185 0.000 1.000 1.000 1.000 1.000 0.980 ! regulation of filopodium assembly GO:0051489 29 28 0.000 1.000 1.000 1.000 1.000 0.765 ! positive regulation of filopodium assembly GO:0051491 22 21 0.000 1.000 1.000 1.000 1.000 0.729 ! regulation of stress fiber assembly GO:0051492 41 40 0.000 1.000 1.000 1.000 1.000 0.797 ! negative regulation of cytoskeleton organization GO:0051494 89 82 0.000 1.000 1.000 1.000 1.000 0.864 ! positive regulation of cytoskeleton organization GO:0051495 104 102 0.000 1.000 1.000 1.000 1.000 0.980 ! positive regulation of stress fiber assembly GO:0051496 26 25 0.000 1.000 1.000 1.000 1.000 0.735 ! histone H3-K4 methylation GO:0051568 21 21 0.000 1.000 1.000 1.000 1.000 0.598 ! regulation of neurotransmitter transport GO:0051588 50 49 0.000 1.000 1.000 1.000 1.000 0.839 ! response to cAMP GO:0051591 31 31 0.000 1.000 1.000 1.000 1.000 0.827 ! response to calcium ion GO:0051592 70 69 0.000 1.000 1.000 1.000 1.000 0.847 ! defense response to virus GO:0051607 124 121 0.000 1.000 1.000 1.000 1.000 0.918 ! mitochondrion localization GO:0051646 21 20 0.000 1.000 1.000 1.000 1.000 0.659 ! vesicle localization GO:0051648 49 46 0.000 1.000 1.000 1.000 1.000 0.852 ! establishment of vesicle localization GO:0051650 26 24 0.000 1.000 1.000 1.000 1.000 0.782 ! maintenance of location in cell GO:0051651 83 81 0.000 1.000 1.000 1.000 1.000 0.878 ! spindle localization GO:0051653 24 22 0.000 1.000 1.000 1.000 1.000 0.707 ! actin filament capping GO:0051693 28 24 0.000 1.000 1.000 1.000 1.000 0.602 ! interaction with host GO:0051701 64 64 0.000 1.000 1.000 1.000 1.000 0.872 ! behavioral interaction between organisms GO:0051705 57 57 0.000 1.000 1.000 1.000 1.000 0.876 ! positive regulation of cell division GO:0051781 55 55 0.000 1.000 1.000 1.000 1.000 0.857 ! regulation of nuclear division GO:0051783 75 72 0.000 1.000 1.000 1.000 1.000 0.887 GO:0007088|regulation of mitosis, ! negative regulation of nuclear division GO:0051784 22 22 0.000 1.000 1.000 1.000 1.000 0.796 GO:0045839|negative regulation of mitosis, ! positive regulation of nuclear division GO:0051785 36 35 0.000 1.000 1.000 1.000 1.000 0.857 GO:0045840|positive regulation of mitosis, ! protein autoubiquitination GO:0051865 34 34 0.000 1.000 1.000 1.000 1.000 0.514 ! regulation of mitochondrial membrane potential GO:0051881 21 21 0.000 1.000 1.000 1.000 1.000 0.756 ! regulation of focal adhesion assembly GO:0051893 21 21 0.000 1.000 1.000 1.000 1.000 0.799 GO:0090109|regulation of cell-substrate junction assembly, ! positive regulation of protein kinase B signaling cascade GO:0051897 63 63 0.000 1.000 1.000 1.000 1.000 0.884 ! membrane depolarization GO:0051899 71 71 0.000 1.000 1.000 1.000 1.000 0.898 ! regulation of calcium ion transport GO:0051924 138 137 0.000 1.000 1.000 1.000 1.000 0.995 ! positive regulation of calcium ion transport GO:0051928 68 67 0.000 1.000 1.000 1.000 1.000 0.888 ! regulation of sensory perception of pain GO:0051930 32 32 0.000 1.000 1.000 1.000 1.000 0.833 GO:0051931|regulation of sensory perception, ! regulation of sensory perception GO:0051931 32 32 0.000 1.000 1.000 1.000 1.000 0.833 GO:0051930|regulation of sensory perception of pain, ! regulation of amine transport GO:0051952 58 58 0.000 1.000 1.000 1.000 1.000 0.899 ! negative regulation of amine transport GO:0051953 24 24 0.000 1.000 1.000 1.000 1.000 0.855 ! positive regulation of amine transport GO:0051954 22 22 0.000 1.000 1.000 1.000 1.000 0.835 ! positive regulation of nervous system development GO:0051962 26 24 0.000 1.000 1.000 1.000 1.000 0.752 GO:0051965|positive regulation of synapse assembly, ! regulation of synapse assembly GO:0051963 36 34 0.000 1.000 1.000 1.000 1.000 0.829 ! positive regulation of synapse assembly GO:0051965 26 24 0.000 1.000 1.000 1.000 1.000 0.752 GO:0051962|positive regulation of nervous system development, ! regulation of synaptic transmission, glutamatergic GO:0051966 38 38 0.000 1.000 1.000 1.000 1.000 0.874 ! positive regulation of synaptic transmission, glutamatergic GO:0051968 20 20 0.000 1.000 1.000 1.000 1.000 0.824 ! negative regulation of transmission of nerve impulse GO:0051970 40 40 0.000 1.000 1.000 1.000 1.000 0.860 ! positive regulation of transmission of nerve impulse GO:0051971 74 74 0.000 1.000 1.000 1.000 1.000 0.901 ! regulation of chromosome segregation GO:0051983 26 25 0.000 1.000 1.000 1.000 1.000 0.776 ! muscle cell development GO:0055001 124 124 0.000 1.000 1.000 1.000 1.000 0.980 ! striated muscle cell development GO:0055002 96 96 0.000 1.000 1.000 1.000 1.000 0.967 ! cardiac cell development GO:0055006 39 39 0.000 1.000 1.000 1.000 1.000 0.862 ! cardiac muscle cell differentiation GO:0055007 58 58 0.000 1.000 1.000 1.000 1.000 0.889 ! cardiac muscle tissue morphogenesis GO:0055008 59 59 0.000 1.000 1.000 1.000 1.000 0.895 ! ventricular cardiac muscle tissue morphogenesis GO:0055010 45 45 0.000 1.000 1.000 1.000 1.000 0.879 ! cardiac muscle cell development GO:0055013 35 35 0.000 1.000 1.000 1.000 1.000 0.845 ! cardiac muscle tissue growth GO:0055017 22 21 0.000 1.000 1.000 1.000 1.000 0.839 ! regulation of cardiac muscle tissue growth GO:0055021 39 39 0.000 1.000 1.000 1.000 1.000 0.873 ! regulation of cardiac muscle tissue development GO:0055024 50 50 0.000 1.000 1.000 1.000 1.000 0.891 ! monovalent inorganic cation homeostasis GO:0055067 59 57 0.000 1.000 1.000 1.000 1.000 0.860 ! iron ion homeostasis GO:0055072 58 58 0.000 1.000 1.000 1.000 1.000 0.627 ! anion homeostasis GO:0055081 21 21 0.000 1.000 1.000 1.000 1.000 0.760 ! lipid homeostasis GO:0055088 76 75 0.000 1.000 1.000 1.000 1.000 0.896 ! sterol homeostasis GO:0055092 50 49 0.000 1.000 1.000 1.000 1.000 0.873 ! regulation of cardiac muscle contraction GO:0055117 39 39 0.000 1.000 1.000 1.000 1.000 0.882 ! palate development GO:0060021 78 77 0.000 1.000 1.000 1.000 1.000 0.883 ! pericardium development GO:0060039 23 23 0.000 1.000 1.000 1.000 1.000 0.799 ! retina morphogenesis in camera-type eye GO:0060042 36 36 0.000 1.000 1.000 1.000 1.000 0.793 ! regulation of cardiac muscle cell proliferation GO:0060043 32 32 0.000 1.000 1.000 1.000 1.000 0.851 ! positive regulation of cardiac muscle cell proliferation GO:0060045 20 20 0.000 1.000 1.000 1.000 1.000 0.843 ! heart contraction GO:0060047 45 45 0.000 1.000 1.000 1.000 1.000 0.852 GO:0003015|heart process, ! cardiac muscle contraction GO:0060048 37 37 0.000 1.000 1.000 1.000 1.000 0.825 ! canonical Wnt receptor signaling pathway GO:0060070 90 90 0.000 1.000 1.000 1.000 1.000 0.900 ! Wnt receptor signaling pathway, planar cell polarity pathway GO:0060071 20 20 0.000 1.000 1.000 1.000 1.000 0.788 GO:0090175|regulation of establishment of planar polarity, ! regulation of postsynaptic membrane potential GO:0060078 47 47 0.000 1.000 1.000 1.000 1.000 0.890 ! regulation of excitatory postsynaptic membrane potential GO:0060079 41 41 0.000 1.000 1.000 1.000 1.000 0.881 ! membrane hyperpolarization GO:0060081 21 21 0.000 1.000 1.000 1.000 1.000 0.790 ! inner ear receptor cell differentiation GO:0060113 49 49 0.000 1.000 1.000 1.000 1.000 0.838 ! inner ear receptor cell development GO:0060119 28 28 0.000 1.000 1.000 1.000 1.000 0.769 ! regulation of lipase activity GO:0060191 108 108 0.000 1.000 1.000 1.000 1.000 0.997 ! positive regulation of lipase activity GO:0060193 80 80 0.000 1.000 1.000 1.000 1.000 0.898 ! cilium morphogenesis GO:0060271 111 107 0.000 1.000 1.000 1.000 1.000 0.702 ! long-term synaptic potentiation GO:0060291 25 25 0.000 1.000 1.000 1.000 1.000 0.831 ! head development GO:0060322 56 54 0.000 1.000 1.000 1.000 1.000 0.847 ! head morphogenesis GO:0060323 39 37 0.000 1.000 1.000 1.000 1.000 0.799 ! face development GO:0060324 43 41 0.000 1.000 1.000 1.000 1.000 0.806 ! face morphogenesis GO:0060325 35 33 0.000 1.000 1.000 1.000 1.000 0.769 ! cell chemotaxis GO:0060326 100 99 0.000 1.000 1.000 1.000 1.000 0.979 ! bone development GO:0060348 107 106 0.000 1.000 1.000 1.000 1.000 0.959 ! bone morphogenesis GO:0060349 68 68 0.000 1.000 1.000 1.000 1.000 0.870 ! endochondral bone morphogenesis GO:0060350 41 41 0.000 1.000 1.000 1.000 1.000 0.823 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 32 32 0.000 1.000 1.000 1.000 1.000 0.858 ! cytosolic calcium ion transport GO:0060401 43 43 0.000 1.000 1.000 1.000 1.000 0.864 ! calcium ion transport into cytosol GO:0060402 42 42 0.000 1.000 1.000 1.000 1.000 0.861 ! cardiac septum morphogenesis GO:0060411 51 51 0.000 1.000 1.000 1.000 1.000 0.888 ! ventricular septum morphogenesis GO:0060412 34 34 0.000 1.000 1.000 1.000 1.000 0.846 ! muscle tissue morphogenesis GO:0060415 67 67 0.000 1.000 1.000 1.000 1.000 0.895 ! heart growth GO:0060419 25 24 0.000 1.000 1.000 1.000 1.000 0.839 ! regulation of heart growth GO:0060420 45 45 0.000 1.000 1.000 1.000 1.000 0.880 ! lung morphogenesis GO:0060425 38 38 0.000 1.000 1.000 1.000 1.000 0.876 ! epithelial tube branching involved in lung morphogenesis GO:0060441 22 22 0.000 1.000 1.000 1.000 1.000 0.809 ! mammary gland morphogenesis GO:0060443 50 50 0.000 1.000 1.000 1.000 1.000 0.883 ! branching involved in mammary gland duct morphogenesis GO:0060444 25 25 0.000 1.000 1.000 1.000 1.000 0.840 ! regulation of cell projection assembly GO:0060491 62 60 0.000 1.000 1.000 1.000 1.000 0.865 ! prostate gland morphogenesis GO:0060512 28 28 0.000 1.000 1.000 1.000 1.000 0.848 ! mammary gland duct morphogenesis GO:0060603 35 35 0.000 1.000 1.000 1.000 1.000 0.878 ! placenta blood vessel development GO:0060674 28 28 0.000 1.000 1.000 1.000 1.000 0.748 ! regulation of morphogenesis of a branching structure GO:0060688 55 55 0.000 1.000 1.000 1.000 1.000 0.897 ! cell differentiation involved in embryonic placenta development GO:0060706 21 21 0.000 1.000 1.000 1.000 1.000 0.705 ! labyrinthine layer development GO:0060711 42 42 0.000 1.000 1.000 1.000 1.000 0.790 ! prostate gland epithelium morphogenesis GO:0060740 27 27 0.000 1.000 1.000 1.000 1.000 0.861 ! mammary gland alveolus development GO:0060749 22 22 0.000 1.000 1.000 1.000 1.000 0.812 GO:0061377|mammary gland lobule development, ! cell fate commitment involved in formation of primary germ layers GO:0060795 26 26 0.000 1.000 1.000 1.000 1.000 0.843 ! artery development GO:0060840 55 54 0.000 1.000 1.000 1.000 1.000 0.895 ! regulation of gene silencing GO:0060968 22 21 0.000 1.000 1.000 1.000 1.000 0.694 ! coronary vasculature development GO:0060976 35 35 0.000 1.000 1.000 1.000 1.000 0.869 ! coronary vasculature morphogenesis GO:0060977 24 24 0.000 1.000 1.000 1.000 1.000 0.849 ! regulation of dendritic spine development GO:0060998 28 28 0.000 1.000 1.000 1.000 1.000 0.815 ! cell differentiation involved in kidney development GO:0061005 23 22 0.000 1.000 1.000 1.000 1.000 0.837 ! membrane fusion GO:0061025 74 70 0.000 1.000 1.000 1.000 1.000 0.830 ! regulation of cartilage development GO:0061035 46 46 0.000 1.000 1.000 1.000 1.000 0.851 ! ovum-producing ovary development GO:0061039 72 72 0.000 1.000 1.000 1.000 1.000 0.887 ! regulation of wound healing GO:0061041 73 73 0.000 1.000 1.000 1.000 1.000 0.896 ! somite development GO:0061053 63 63 0.000 1.000 1.000 1.000 1.000 0.877 ! chaperone-mediated protein folding GO:0061077 29 28 0.000 1.000 1.000 1.000 1.000 0.572 ! regulation of protein tyrosine kinase activity GO:0061097 47 47 0.000 1.000 1.000 1.000 1.000 0.844 ! positive regulation of protein tyrosine kinase activity GO:0061098 29 29 0.000 1.000 1.000 1.000 1.000 0.822 ! regulation of proteasomal protein catabolic process GO:0061136 70 69 0.000 1.000 1.000 1.000 1.000 0.849 ! regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 32 32 0.000 1.000 1.000 1.000 1.000 0.784 ! mammary gland epithelium development GO:0061180 55 55 0.000 1.000 1.000 1.000 1.000 0.896 ! retina vasculature development in camera-type eye GO:0061298 23 23 0.000 1.000 1.000 1.000 1.000 0.608 ! renal tubule development GO:0061326 24 24 0.000 1.000 1.000 1.000 1.000 0.854 ! cardiac conduction GO:0061337 27 26 0.000 1.000 1.000 1.000 1.000 0.812 ! neural precursor cell proliferation GO:0061351 54 54 0.000 1.000 1.000 1.000 1.000 0.858 ! determination of heart left/right asymmetry GO:0061371 47 47 0.000 1.000 1.000 1.000 1.000 0.886 ! mammary gland lobule development GO:0061377 22 22 0.000 1.000 1.000 1.000 1.000 0.812 GO:0060749|mammary gland alveolus development, ! regulation of extent of cell growth GO:0061387 57 55 0.000 1.000 1.000 1.000 1.000 0.855 ! apoptosis in response to endoplasmic reticulum stress GO:0070059 20 20 0.000 1.000 1.000 1.000 1.000 0.650 ! chemokine-mediated signaling pathway GO:0070098 28 28 0.000 1.000 1.000 1.000 1.000 0.637 ! regulation of biomineral tissue development GO:0070167 66 64 0.000 1.000 1.000 1.000 1.000 0.866 ! positive regulation of biomineral tissue development GO:0070169 30 29 0.000 1.000 1.000 1.000 1.000 0.849 ! chromosome organization involved in meiosis GO:0070192 33 33 0.000 1.000 1.000 1.000 1.000 0.719 ! regulation of lymphocyte apoptosis GO:0070228 35 35 0.000 1.000 1.000 1.000 1.000 0.862 ! negative regulation of lymphocyte apoptosis GO:0070229 21 21 0.000 1.000 1.000 1.000 1.000 0.807 ! cellular response to hydrogen peroxide GO:0070301 36 36 0.000 1.000 1.000 1.000 1.000 0.830 ! regulation of stress-activated protein kinase signaling cascade GO:0070302 143 143 0.000 1.000 1.000 1.000 1.000 0.985 ! negative regulation of stress-activated protein kinase signaling cascade GO:0070303 24 24 0.000 1.000 1.000 1.000 1.000 0.707 GO:0032873|negative regulation of stress-activated MAPK cascade, ! positive regulation of stress-activated protein kinase signaling cascade GO:0070304 58 58 0.000 1.000 1.000 1.000 1.000 0.867 ! triglyceride homeostasis GO:0070328 20 20 0.000 1.000 1.000 1.000 1.000 0.781 ! ERK1 and ERK2 cascade GO:0070371 21 21 0.000 1.000 1.000 1.000 1.000 0.823 ! positive regulation of ERK1 and ERK2 cascade GO:0070374 92 90 0.000 1.000 1.000 1.000 1.000 0.902 ! response to oxygen levels GO:0070482 183 181 0.000 1.000 1.000 1.000 1.000 0.928 ! regulation of microtubule cytoskeleton organization GO:0070507 93 88 0.000 1.000 1.000 1.000 1.000 0.962 ! calcium ion import GO:0070509 22 22 0.000 1.000 1.000 1.000 1.000 0.721 ! protein K63-linked ubiquitination GO:0070534 25 25 0.000 1.000 1.000 1.000 1.000 0.670 ! response to interleukin-1 GO:0070555 39 38 0.000 1.000 1.000 1.000 1.000 0.866 ! protein localization in mitochondrion GO:0070585 35 34 0.000 1.000 1.000 1.000 1.000 0.705 ! calcium ion transmembrane transport GO:0070588 97 96 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of protein processing GO:0070613 34 33 0.000 1.000 1.000 1.000 1.000 0.779 ! protein modification by small protein removal GO:0070646 81 75 0.000 1.000 1.000 1.000 1.000 0.623 ! leukocyte proliferation GO:0070661 55 55 0.000 1.000 1.000 1.000 1.000 0.845 ! regulation of leukocyte proliferation GO:0070663 164 162 0.000 1.000 1.000 1.000 1.000 0.996 ! negative regulation of leukocyte proliferation GO:0070664 57 57 0.000 1.000 1.000 1.000 1.000 0.873 ! positive regulation of leukocyte proliferation GO:0070665 106 105 0.000 1.000 1.000 1.000 1.000 0.904 ! response to interleukin-4 GO:0070670 23 23 0.000 1.000 1.000 1.000 1.000 0.708 ! regulation of glycogen metabolic process GO:0070873 29 29 0.000 1.000 1.000 1.000 1.000 0.819 ! protein K48-linked ubiquitination GO:0070936 38 38 0.000 1.000 1.000 1.000 1.000 0.418 ! protein localization in endoplasmic reticulum GO:0070972 20 20 0.000 1.000 1.000 1.000 1.000 0.648 ! protein K11-linked ubiquitination GO:0070979 25 25 0.000 1.000 1.000 1.000 1.000 0.370 ! demethylation GO:0070988 41 40 0.000 1.000 1.000 1.000 1.000 0.813 ! neuron death GO:0070997 38 38 0.000 1.000 1.000 1.000 1.000 0.822 ! positive regulation of cell cycle arrest GO:0071158 29 28 0.000 1.000 1.000 1.000 1.000 0.790 ! cellular response to biotic stimulus GO:0071216 143 140 0.000 1.000 1.000 1.000 1.000 0.930 ! cellular response to molecule of bacterial origin GO:0071219 131 128 0.000 1.000 1.000 1.000 1.000 0.927 ! cellular response to lipopolysaccharide GO:0071222 123 120 0.000 1.000 1.000 1.000 1.000 0.920 ! cellular response to inorganic substance GO:0071241 105 104 0.000 1.000 1.000 1.000 1.000 0.730 ! cellular response to metal ion GO:0071248 54 53 0.000 1.000 1.000 1.000 1.000 0.859 ! cellular response to calcium ion GO:0071277 26 25 0.000 1.000 1.000 1.000 1.000 0.699 ! cellular response to carbohydrate stimulus GO:0071322 30 30 0.000 1.000 1.000 1.000 1.000 0.719 ! cellular response to monosaccharide stimulus GO:0071326 26 26 0.000 1.000 1.000 1.000 1.000 0.651 GO:0071333|cellular response to glucose stimulus, GO:0071331|cellular response to hexose stimulus, ! cellular response to hexose stimulus GO:0071331 26 26 0.000 1.000 1.000 1.000 1.000 0.651 GO:0071326|cellular response to monosaccharide stimulus, GO:0071333|cellular response to glucose stimulus, ! cellular response to glucose stimulus GO:0071333 26 26 0.000 1.000 1.000 1.000 1.000 0.651 GO:0071326|cellular response to monosaccharide stimulus, GO:0071331|cellular response to hexose stimulus, ! cellular response to interferon-gamma GO:0071346 26 26 0.000 1.000 1.000 1.000 1.000 0.706 ! cellular response to interleukin-1 GO:0071347 26 25 0.000 1.000 1.000 1.000 1.000 0.821 ! cellular response to interleukin-4 GO:0071353 21 21 0.000 1.000 1.000 1.000 1.000 0.670 ! cellular response to tumor necrosis factor GO:0071356 43 41 0.000 1.000 1.000 1.000 1.000 0.849 ! cellular response to dsRNA GO:0071359 24 22 0.000 1.000 1.000 1.000 1.000 0.700 ! cellular response to organic cyclic compound GO:0071407 41 41 0.000 1.000 1.000 1.000 1.000 0.858 ! cellular response to oxygen levels GO:0071453 36 35 0.000 1.000 1.000 1.000 1.000 0.831 ! cellular response to hypoxia GO:0071456 33 32 0.000 1.000 1.000 1.000 1.000 0.811 ! cellular response to xenobiotic stimulus GO:0071466 35 35 0.000 1.000 1.000 1.000 1.000 0.737 GO:0006805|xenobiotic metabolic process, ! anatomical structure maturation GO:0071695 46 46 0.000 1.000 1.000 1.000 1.000 0.869 ! nitrogen compound transport GO:0071705 166 166 0.000 1.000 1.000 1.000 1.000 0.962 ! response to fibroblast growth factor stimulus GO:0071774 47 47 0.000 1.000 1.000 1.000 1.000 0.826 GO:0044344|cellular response to fibroblast growth factor stimulus, ! G1/S transition checkpoint GO:0071779 31 31 0.000 1.000 1.000 1.000 1.000 0.793 ! cellular potassium ion transport GO:0071804 86 86 0.000 1.000 1.000 1.000 1.000 0.678 GO:0071805|potassium ion transmembrane transport, ! potassium ion transmembrane transport GO:0071805 86 86 0.000 1.000 1.000 1.000 1.000 0.678 GO:0071804|cellular potassium ion transport, ! protein-lipid complex subunit organization GO:0071825 25 25 0.000 1.000 1.000 1.000 1.000 0.838 GO:0071827|plasma lipoprotein particle organization, ! ribonucleoprotein complex subunit organization GO:0071826 80 79 0.000 1.000 1.000 1.000 1.000 0.802 ! plasma lipoprotein particle organization GO:0071827 25 25 0.000 1.000 1.000 1.000 1.000 0.838 GO:0071825|protein-lipid complex subunit organization, ! negative regulation of protein serine/threonine kinase activity GO:0071901 86 86 0.000 1.000 1.000 1.000 1.000 0.890 ! positive regulation of protein serine/threonine kinase activity GO:0071902 200 198 0.000 1.000 1.000 1.000 1.000 0.988 ! nephron tubule development GO:0072080 20 20 0.000 1.000 1.000 1.000 1.000 0.845 ! mesenchyme morphogenesis GO:0072132 22 22 0.000 1.000 1.000 1.000 1.000 0.877 ! monocarboxylic acid catabolic process GO:0072329 50 50 0.000 1.000 1.000 1.000 1.000 0.840 ! signal transduction by p53 class mediator GO:0072331 58 57 0.000 1.000 1.000 1.000 1.000 0.857 ! signal transduction by p53 class mediator resulting in induction of apoptosis GO:0072332 34 33 0.000 1.000 1.000 1.000 1.000 0.776 ! protein activation cascade GO:0072376 43 42 0.000 1.000 1.000 1.000 1.000 0.618 ! organelle transport along microtubule GO:0072384 25 23 0.000 1.000 1.000 1.000 1.000 0.736 ! purine-containing compound biosynthetic process GO:0072522 112 112 0.000 1.000 1.000 1.000 1.000 0.980 ! pyridine-containing compound metabolic process GO:0072524 55 55 0.000 1.000 1.000 1.000 1.000 0.857 GO:0019362|pyridine nucleotide metabolic process, ! reactive oxygen species metabolic process GO:0072593 70 70 0.000 1.000 1.000 1.000 1.000 0.865 ! establishment of protein localization to organelle GO:0072594 79 78 0.000 1.000 1.000 1.000 1.000 0.865 ! establishment of protein localization in mitochondrion GO:0072655 34 33 0.000 1.000 1.000 1.000 1.000 0.698 ! protein localization in membrane GO:0072657 92 88 0.000 1.000 1.000 1.000 1.000 0.889 ! protein localization in plasma membrane GO:0072659 56 52 0.000 1.000 1.000 1.000 1.000 0.833 ! regulation of cardiac muscle cell action potential GO:0086001 25 25 0.000 1.000 1.000 1.000 1.000 0.815 ! regulation of cardiac muscle cell contraction GO:0086004 24 24 0.000 1.000 1.000 1.000 1.000 0.819 ! regulation of cardiac muscle cell membrane potential GO:0086036 26 26 0.000 1.000 1.000 1.000 1.000 0.811 ! establishment of protein localization in plasma membrane GO:0090002 26 24 0.000 1.000 1.000 1.000 1.000 0.746 ! regulation of establishment of protein localization in plasma membrane GO:0090003 24 23 0.000 1.000 1.000 1.000 1.000 0.764 ! regulation of neutrophil chemotaxis GO:0090022 20 20 0.000 1.000 1.000 1.000 1.000 0.779 ! regulation of peptide transport GO:0090087 130 129 0.000 1.000 1.000 1.000 1.000 0.984 GO:0002791|regulation of peptide secretion, ! cochlea development GO:0090102 31 31 0.000 1.000 1.000 1.000 1.000 0.846 ! cochlea morphogenesis GO:0090103 22 22 0.000 1.000 1.000 1.000 1.000 0.814 ! regulation of cell-substrate junction assembly GO:0090109 21 21 0.000 1.000 1.000 1.000 1.000 0.799 GO:0051893|regulation of focal adhesion assembly, ! establishment of protein localization in membrane GO:0090150 28 26 0.000 1.000 1.000 1.000 1.000 0.761 ! regulation of establishment of planar polarity GO:0090175 20 20 0.000 1.000 1.000 1.000 1.000 0.788 GO:0060071|Wnt receptor signaling pathway, planar cell polarity pathway, ! regulation of kidney development GO:0090183 50 50 0.000 1.000 1.000 1.000 1.000 0.900 ! regulation of branching involved in ureteric bud morphogenesis GO:0090189 24 24 0.000 1.000 1.000 1.000 1.000 0.836 ! positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 22 22 0.000 1.000 1.000 1.000 1.000 0.824 ! regulation of release of cytochrome c from mitochondria GO:0090199 34 33 0.000 1.000 1.000 1.000 1.000 0.818 ! positive regulation of release of cytochrome c from mitochondria GO:0090200 23 22 0.000 1.000 1.000 1.000 1.000 0.728 ! regulation of triglyceride metabolic process GO:0090207 26 25 0.000 1.000 1.000 1.000 1.000 0.798 ! positive regulation of lipid kinase activity GO:0090218 25 25 0.000 1.000 1.000 1.000 1.000 0.813 ! positive regulation of canonical Wnt receptor signaling pathway GO:0090263 50 49 0.000 1.000 1.000 1.000 1.000 0.833 ! regulation of peptide hormone secretion GO:0090276 128 127 0.000 1.000 1.000 1.000 1.000 0.984 ! positive regulation of peptide hormone secretion GO:0090277 61 60 0.000 1.000 1.000 1.000 1.000 0.881 ! negative regulation of peptide hormone secretion GO:0090278 38 38 0.000 1.000 1.000 1.000 1.000 0.828 ! regulation of calcium ion import GO:0090279 20 20 0.000 1.000 1.000 1.000 1.000 0.799 ! regulation of cellular response to growth factor stimulus GO:0090287 29 29 0.000 1.000 1.000 1.000 1.000 0.826 ! nucleic acid phosphodiester bond hydrolysis GO:0090305 50 49 0.000 1.000 1.000 1.000 1.000 0.822 ! cellular senescence GO:0090398 24 24 0.000 1.000 1.000 1.000 1.000 0.803 ! regulation of plasma lipoprotein particle levels GO:0097006 36 36 0.000 1.000 1.000 1.000 1.000 0.874 ! activation of cysteine-type endopeptidase activity GO:0097202 74 74 0.000 1.000 1.000 1.000 1.000 0.879 ! regulation of hemostasis GO:1900046 53 53 0.000 1.000 1.000 1.000 1.000 0.876 GO:0030193|regulation of blood coagulation, ! negative regulation of hemostasis GO:1900047 25 25 0.000 1.000 1.000 1.000 1.000 0.726 GO:0030195|negative regulation of blood coagulation, ! negative regulation of cellular response to insulin stimulus GO:1900077 28 27 0.000 1.000 1.000 1.000 1.000 0.800 ! regulation of ion homeostasis GO:2000021 158 154 0.000 1.000 1.000 1.000 1.000 0.995 ! regulation of organ morphogenesis GO:2000027 135 135 0.000 1.000 1.000 1.000 1.000 1.00 ! regulation of leukocyte apoptosis GO:2000106 48 48 0.000 1.000 1.000 1.000 1.000 0.889 ! negative regulation of leukocyte apoptosis GO:2000107 30 30 0.000 1.000 1.000 1.000 1.000 0.855 ! positive regulation of neural precursor cell proliferation GO:2000179 36 36 0.000 1.000 1.000 1.000 1.000 0.863 ! regulation of fatty acid transport GO:2000191 24 24 0.000 1.000 1.000 1.000 1.000 0.828 ! positive regulation of receptor activity GO:2000273 22 22 0.000 1.000 1.000 1.000 1.000 0.839 ! regulation of reactive oxygen species metabolic process GO:2000377 60 60 0.000 1.000 1.000 1.000 1.000 0.883 ! positive regulation of reactive oxygen species metabolic process GO:2000379 33 33 0.000 1.000 1.000 1.000 1.000 0.841 ! regulation of lymphocyte migration GO:2000401 24 23 0.000 1.000 1.000 1.000 1.000 0.813 ! regulation of CD4-positive, alpha-beta T cell activation GO:2000514 30 30 0.000 1.000 1.000 1.000 1.000 0.857 ! positive regulation of CD4-positive, alpha-beta T cell activation GO:2000516 21 21 0.000 1.000 1.000 1.000 1.000 0.824 ! regulation of stem cell differentiation GO:2000736 22 22 0.000 1.000 1.000 1.000 1.000 0.797 ! regulation of skeletal muscle cell differentiation GO:2001014 33 33 0.000 1.000 1.000 1.000 1.000 0.626 ! regulation of response to DNA damage stimulus GO:2001020 84 82 0.000 1.000 1.000 1.000 1.000 0.883 ! positive regulation of response to DNA damage stimulus GO:2001022 46 45 0.000 1.000 1.000 1.000 1.000 0.826 ! positive regulation of cysteine-type endopeptidase activity GO:2001056 101 100 0.000 1.000 1.000 1.000 1.000 0.981 ! regulation of apoptotic signaling pathway GO:2001233 58 58 0.000 1.000 1.000 1.000 1.000 0.854 ! negative regulation of apoptotic signaling pathway GO:2001234 21 21 0.000 1.000 1.000 1.000 1.000 0.673 ! positive regulation of apoptotic signaling pathway GO:2001235 39 39 0.000 1.000 1.000 1.000 1.000 0.817 ! regulation of extrinsic apoptotic signaling pathway GO:2001236 30 30 0.000 1.000 1.000 1.000 1.000 0.731 ! regulation of intrinsic apoptotic signaling pathway GO:2001242 25 25 0.000 1.000 1.000 1.000 1.000 0.770 ! regulation of cation channel activity GO:2001257 26 26 0.000 1.000 1.000 1.000 1.000 0.801 !#====== End run =======