# ErmineJ results file # Created Sat Apr 27 21:08:31 PDT 2013 # If you use this file in your research, please cite: # Lee H.K., Braynen W., Keshav K. and Pavlidis P. (2005) # ErmineJ: Tool for functional analysis of gene expression data sets. BMC Bioinformatics 6:269 # See http://www.chibi.ubc.ca/ermineJ for more information # Do not edit this file or you may not be able to reload it into ErmineJ. Edit a copy instead. # Start output of analysis run: MANALO_HYPOXIA_UP # Settings scoreThreshold = 1.0 maxClassSize = 200 minClassSize = 20 rawFile = scoreFile = QuickList.MANALO_HYPOXIA_UP.txt scoreCol = 2 classFile = go_daily-termdb.rdf-xml.gz bigIsBetter = false doLog = true geneRepTreatment = MEAN annotFile = Generic_human_noParents.an.txt.gz annotFormat = DEFAULT classScoreMethod = ORA multifuncCorr = true useGOMolecularFunction = false useGOBiologicalProcess = true useGOCellularComponent = false useUserDefinedGroups = false multifunctionalityCorrelation=0.1134 multifunctionalityEnrichment=0.6410 multifunctionalityEnrichmentPvalue=2.555e-12 numAboveThreshold=202 #!---- !# runName=MANALO_HYPOXIA_UP # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue MFPvalue CorrectedMFPvalue Multifuntionality Same as GeneMembers ! regulation of blood pressure GO:0008217 140 140 12.000 6.345E-08 1.438E-04 0.21042272 1.000 0.946 ! regulation of angiogenesis GO:0045765 157 157 12.000 2.241E-07 2.54E-04 2.06E-03 0.42448194 0.946 ! cellular response to hypoxia GO:0071456 81 81 9.000 3.214E-07 2.428E-04 3.606E-05 0.04087681 0.882 ! cellular response to oxygen levels GO:0071453 88 88 9.000 6.575E-07 3.727E-04 6.16E-05 0.03491431 0.886 ! placenta development GO:0001890 133 133 10.000 2.714E-06 1.231E-03 4.02E-03 0.47964181 0.946 ! positive regulation of angiogenesis GO:0045766 89 89 8.000 7.4E-06 2.796E-03 3.36E-03 0.50781569 0.882 ! negative regulation of smooth muscle cell proliferation GO:0048662 26 26 5.000 9.45E-06 3.06E-03 1.000 1.000 0.798 ! regulation of smooth muscle cell proliferation GO:0048660 67 67 7.000 1.03E-05 2.92E-03 1.000 1.000 0.886 ! regulation of systemic arterial blood pressure GO:0003073 68 68 7.000 1.138E-05 2.866E-03 0.53848318 1.000 0.888 ! peptidyl-proline modification GO:0018208 29 29 5.000 1.66E-05 3.762E-03 1.66E-05 0.03762498 0.508 ! negative regulation of cell-substrate adhesion GO:0010812 33 33 5.000 3.198E-05 6.59E-03 0.05324187 1.000 0.835 ! heart morphogenesis GO:0003007 176 176 10.000 3.204E-05 6.053E-03 0.31954359 1.000 0.946 ! patterning of blood vessels GO:0001569 34 34 5.000 3.715E-05 6.478E-03 6.551E-03 0.64568915 0.819 ! platelet degranulation GO:0002576 83 83 7.000 4.225E-05 6.841E-03 0.24076934 1.000 0.946 ! female pregnancy GO:0007565 147 147 9.000 4.469E-05 6.754E-03 1.414E-03 0.35622041 0.946 ! collagen fibril organization GO:0030199 37 37 5.000 5.662E-05 8.022E-03 5.662E-05 0.0427822 0.753 ! negative regulation of cell adhesion GO:0007162 88 88 7.000 6.16E-05 8.215E-03 0.01759226 1.000 0.878 ! polysaccharide biosynthetic process GO:0000271 124 124 8.000 8.241E-05 0.01037902 5.195E-04 0.23551968 0.946 ! negative regulation of phosphorylation GO:0042326 93 93 7.000 8.767E-05 0.01046067 0.08811156 1.000 0.886 ! regulation of protein autophosphorylation GO:0031952 23 23 4.000 1.178E-04 0.01335749 1.000 1.000 0.762 ! negative regulation of phosphorus metabolic process GO:0010563 98 98 7.000 1.221E-04 0.0131809 0.09925685 1.000 0.946 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of phosphate metabolic process GO:0045936 98 98 7.000 1.221E-04 0.0131809 0.09925685 1.000 0.946 GO:0010563|negative regulation of phosphorus metabolic process, ! cardiac chamber morphogenesis GO:0003206 99 99 7.000 1.301E-04 0.01341134 0.30763657 1.000 0.891 ! negative regulation of cellular carbohydrate metabolic process GO:0010677 25 25 4.000 1.654E-04 0.01630259 0.03206922 1.000 0.817 ! regulation of chemotaxis GO:0050920 103 103 7.000 1.668E-04 0.01575341 0.69037182 1.000 0.891 ! negative regulation of carbohydrate metabolic process GO:0045912 26 26 4.000 1.938E-04 0.01756956 0.03448827 1.000 0.824 ! morphogenesis of a branching structure GO:0001763 179 179 9.000 2.02E-04 0.01761688 0.05254093 1.000 0.946 ! regulation of carbohydrate metabolic process GO:0006109 109 108 7.000 2.238E-04 0.01879482 0.34484336 1.000 0.946 ! ventricular septum morphogenesis GO:0060412 27 27 4.000 2.255E-04 0.0182535 0.26410385 1.000 0.848 ! positive regulation of chemotaxis GO:0050921 77 77 6.000 2.337E-04 0.01826676 1.000 1.000 0.889 ! regulation of muscle cell differentiation GO:0051147 111 110 7.000 2.507E-04 0.01894263 0.35303046 1.000 0.946 ! regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061418 28 28 4.000 2.607E-04 0.01906592 3.768E-03 0.47460641 0.717 ! cell maturation GO:0048469 112 112 7.000 2.8E-04 0.01983855 0.36118204 1.000 0.946 ! positive regulation of leukocyte chemotaxis GO:0002690 52 52 5.000 2.943E-04 0.02021994 1.000 1.000 0.883 ! cardiac chamber development GO:0003205 113 113 7.000 2.957E-04 0.01971717 0.36524373 1.000 0.946 ! morphogenesis of a branching epithelium GO:0061138 151 151 8.000 3.209E-04 0.02078325 0.09186992 1.000 0.946 ! regulation of glucose metabolic process GO:0010906 83 83 6.000 3.518E-04 0.02215177 0.24076934 1.000 0.883 ! leukocyte chemotaxis GO:0030595 84 84 6.000 3.753E-04 0.02299583 0.2449464 1.000 0.880 ! developmental maturation GO:0021700 157 157 8.000 4.169E-04 0.02486853 0.26121288 1.000 0.946 ! regulation of leukocyte migration GO:0002685 87 86 6.000 4.261E-04 0.02476846 1.000 1.000 0.890 ! negative regulation of cell activation GO:0050866 121 120 7.000 4.263E-04 0.02416163 0.39338465 1.000 0.946 ! muscle cell development GO:0055001 122 121 7.000 4.482E-04 0.0247844 0.39735997 1.000 0.946 ! positive regulation of behavior GO:0048520 88 88 6.000 4.821E-04 0.02602154 1.000 1.000 0.891 ! positive regulation of muscle cell differentiation GO:0051149 58 58 5.000 4.913E-04 0.02590302 0.13930217 1.000 0.844 ! smooth muscle cell differentiation GO:0051145 33 33 4.000 4.986E-04 0.02568864 0.3126266 1.000 0.834 ! regulation of cell-matrix adhesion GO:0001952 59 59 5.000 5.32E-04 0.02679854 0.48866305 1.000 0.875 ! regeneration GO:0031099 90 90 6.000 5.437E-04 0.0267928 0.27004864 1.000 0.946 ! regulation of leukocyte chemotaxis GO:0002688 60 60 5.000 5.751E-04 0.02773715 1.000 1.000 0.886 ! cardiac ventricle development GO:0003231 91 91 6.000 5.766E-04 0.02723439 0.27423375 1.000 0.890 ! embryo implantation GO:0007566 35 35 4.000 6.268E-04 0.02900121 6.268E-04 0.23684322 0.686 ! somatic stem cell maintenance GO:0035019 36 36 4.000 6.99E-04 0.03169378 0.06215915 1.000 0.811 ! glycosaminoglycan biosynthetic process GO:0006024 95 95 6.000 7.244E-04 0.03220103 7.244E-04 0.23460751 0.946 ! aminoglycan biosynthetic process GO:0006023 96 96 6.000 7.656E-04 0.03337564 7.656E-04 0.21694163 0.946 ! regulation of transcription from RNA polymerase II promoter in response to stress GO:0043618 37 37 4.000 7.769E-04 0.03323047 8.299E-03 0.72357457 0.801 ! negative regulation of lymphocyte activation GO:0051250 98 97 6.000 8.085E-04 0.03394177 0.29930555 1.000 0.946 ! positive regulation of leukocyte migration GO:0002687 65 65 5.000 8.31E-04 0.03425398 1.000 1.000 0.886 ! regulation of fat cell differentiation GO:0045598 67 65 5.000 8.31E-04 0.0336423 0.16683234 1.000 0.853 ! regulation of behavior GO:0050795 137 137 7.000 9.388E-04 0.0373382 0.79004918 1.000 0.946 ! renal system process GO:0003014 67 67 5.000 9.542E-04 0.03729504 1.000 1.000 0.889 ! regulation of striated muscle cell differentiation GO:0051153 69 68 5.000 1.021E-03 0.03921489 0.53848318 1.000 0.879 ! ventricular septum development GO:0003281 40 40 4.000 1.047E-03 0.03956125 0.36522623 1.000 0.864 ! regulation of cellular carbohydrate metabolic process GO:0010675 104 103 6.000 1.106E-03 0.0411206 0.32423803 1.000 0.946 ! organ regeneration GO:0031100 42 42 4.000 1.26E-03 0.04607348 0.37950505 1.000 0.827 ! regulation of DNA-dependent transcription in response to stress GO:0043620 42 42 4.000 1.26E-03 0.04534215 0.01176774 0.86056337 0.812 ! cell chemotaxis GO:0060326 106 106 6.000 1.284E-03 0.04547683 0.3366234 1.000 0.946 ! regulation of cell-substrate adhesion GO:0010810 107 107 6.000 1.348E-03 0.04699936 0.34073731 1.000 0.946 ! cardiac septum morphogenesis GO:0060411 43 43 4.000 1.377E-03 0.0473033 0.38652415 1.000 0.878 ! positive regulation of response to cytokine stimulus GO:0060760 20 20 3.000 1.401E-03 0.04741037 1.000 1.000 0.791 ! branching morphogenesis of a tube GO:0048754 147 147 7.000 1.414E-03 0.04714682 0.0257145 1.000 0.946 ! positive regulation of endothelial cell migration GO:0010595 44 44 4.000 1.502E-03 0.0493366 1.000 1.000 0.868 ! regulation of inflammatory response GO:0050727 194 193 8.000 1.596E-03 0.05168527 0.37192338 1.000 0.946 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 21 21 3.000 1.621E-03 0.05176451 1.000 1.000 0.845 ! regulation of glycolysis GO:0006110 21 21 3.000 1.621E-03 0.05104556 0.0231171 1.000 0.773 ! negative regulation of leukocyte activation GO:0002695 112 111 6.000 1.627E-03 0.0505228 0.35711085 1.000 0.946 ! artery morphogenesis GO:0048844 45 45 4.000 1.634E-03 0.05005032 1.000 1.000 0.880 ! positive regulation of response to external stimulus GO:0032103 153 153 7.000 1.779E-03 0.0537656 0.82517395 1.000 0.946 ! negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433 113 113 6.000 1.782E-03 0.05315667 0.13575876 1.000 0.946 ! regulation of epithelial cell proliferation GO:0050678 197 197 8.000 1.816E-03 0.05346015 0.38416594 1.000 0.946 ! response to fluid shear stress GO:0034405 22 22 3.000 1.862E-03 0.05410811 1.000 1.000 0.831 ! positive regulation of blood vessel endothelial cell migration GO:0043536 22 22 3.000 1.862E-03 0.05342319 1.000 1.000 0.800 ! plasma membrane organization GO:0007009 80 78 5.000 1.888E-03 0.05349291 0.01173241 0.88657927 0.852 ! proteoglycan biosynthetic process GO:0030166 47 47 4.000 1.922E-03 0.0537872 1.922E-03 0.43567635 0.770 ! sulfur compound biosynthetic process GO:0044272 115 115 6.000 1.948E-03 0.05386013 9.832E-03 0.82554895 0.946 ! positive regulation of epithelial cell proliferation GO:0050679 115 115 6.000 1.948E-03 0.05321122 0.37333734 1.000 0.946 ! regulation of oligodendrocyte differentiation GO:0048713 24 23 3.000 2.123E-03 0.05730268 0.22987685 1.000 0.807 ! positive regulation of neurogenesis GO:0050769 119 118 6.000 2.219E-03 0.05918298 0.73911812 1.000 0.946 ! regulation of wound healing GO:0061041 81 81 5.000 2.23E-03 0.05877425 0.60203813 1.000 0.887 ! cardiac atrium morphogenesis GO:0003209 24 24 3.000 2.407E-03 0.06270877 1.000 1.000 0.846 ! prostanoid metabolic process GO:0006692 24 24 3.000 2.407E-03 0.06199617 0.02972066 1.000 0.733 GO:0006693|prostaglandin metabolic process, ! prostaglandin metabolic process GO:0006693 24 24 3.000 2.407E-03 0.06199617 0.02972066 1.000 0.733 GO:0006692|prostanoid metabolic process, ! positive regulation of glial cell differentiation GO:0045687 25 24 3.000 2.407E-03 0.06129958 0.2385793 1.000 0.827 ! positive chemotaxis GO:0050918 24 24 3.000 2.407E-03 0.06061847 1.000 1.000 0.794 ! regulation of heart contraction GO:0008016 121 121 6.000 2.517E-03 0.06271283 0.74790919 1.000 0.946 ! cardiac muscle tissue development GO:0048738 122 121 6.000 2.517E-03 0.06203117 0.39735997 1.000 0.946 ! negative regulation of cell migration GO:0030336 123 122 6.000 2.623E-03 0.06394425 0.75077353 1.000 0.946 ! negative regulation of response to external stimulus GO:0032102 123 122 6.000 2.623E-03 0.06326399 0.15955911 1.000 0.946 ! maternal placenta development GO:0001893 25 25 3.000 2.712E-03 0.0647209 2.712E-03 0.51237381 0.707 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 25 25 3.000 2.712E-03 0.06404673 0.03206922 1.000 0.796 ! proteoglycan metabolic process GO:0006029 86 86 5.000 2.897E-03 0.06769799 2.897E-03 0.50513116 0.946 ! negative regulation of cell motility GO:2000146 126 125 6.000 2.961E-03 0.06849198 0.75917371 1.000 0.946 ! artery development GO:0060840 53 53 4.000 2.994E-03 0.06855249 1.000 1.000 0.885 ! heart valve development GO:0003170 26 26 3.000 3.041E-03 0.0689317 1.000 1.000 0.862 ! regulation of smooth muscle cell migration GO:0014910 26 26 3.000 3.041E-03 0.06824921 1.000 1.000 0.844 ! calcium-dependent cell-cell adhesion GO:0016339 26 26 3.000 3.041E-03 0.0675801 3.041E-03 0.49236929 0.00663 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 26 26 3.000 3.041E-03 0.06692398 0.25569171 1.000 0.807 ! negative regulation of B cell activation GO:0050869 26 26 3.000 3.041E-03 0.06628048 1.000 1.000 0.793 ! regulation of cell division GO:0051302 89 87 5.000 3.046E-03 0.06575654 0.25749242 1.000 0.946 ! positive regulation of MAPK cascade GO:0043410 171 170 7.000 3.215E-03 0.06876072 0.30103709 1.000 0.946 ! negative regulation of transferase activity GO:0051348 171 171 7.000 3.321E-03 0.07036251 0.0447323 1.000 0.946 ! cardiac atrium development GO:0003230 27 27 3.000 3.393E-03 0.07121231 1.000 1.000 0.857 ! chondroitin sulfate biosynthetic process GO:0030206 27 27 3.000 3.393E-03 0.07055898 3.393E-03 0.48068307 0.677 ! regulation of vascular permeability GO:0043114 27 27 3.000 3.393E-03 0.06991754 1.000 1.000 0.813 ! platelet-derived growth factor receptor signaling pathway GO:0048008 27 27 3.000 3.393E-03 0.06928765 0.26410385 1.000 0.730 ! negative regulation of leukocyte apoptosis GO:2000107 27 27 3.000 3.393E-03 0.06866901 1.000 1.000 0.844 ! negative regulation of lipid metabolic process GO:0045833 55 55 4.000 3.426E-03 0.06873947 1.000 1.000 0.884 ! lipid localization GO:0010876 172 172 7.000 3.43E-03 0.06820119 0.85936526 1.000 0.946 ! regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043281 173 172 7.000 3.43E-03 0.06760814 0.58056728 1.000 0.946 ! negative regulation of endopeptidase activity GO:0010951 132 130 6.000 3.594E-03 0.07024586 0.77255249 1.000 0.946 ! chondroitin sulfate metabolic process GO:0030204 56 56 4.000 3.658E-03 0.07087459 3.658E-03 0.48778393 0.759 ! regulation of generation of precursor metabolites and energy GO:0043467 56 56 4.000 3.658E-03 0.07027396 0.13163403 1.000 0.868 ! cell-substrate adhesion GO:0031589 132 131 6.000 3.732E-03 0.07110257 0.18451824 1.000 0.946 ! negative regulation of cellular component movement GO:0051271 132 131 6.000 3.732E-03 0.07051005 0.77513814 1.000 0.946 ! negative regulation of tumor necrosis factor production GO:0032720 28 28 3.000 3.768E-03 0.07060261 1.000 1.000 0.832 ! brown fat cell differentiation GO:0050873 28 28 3.000 3.768E-03 0.0700239 0.27242139 1.000 0.659 ! regulation of cellular response to growth factor stimulus GO:0090287 28 28 3.000 3.768E-03 0.0694546 0.27242139 1.000 0.810 ! regulation of heart rate GO:0002027 57 57 4.000 3.9E-03 0.07129552 1.000 1.000 0.884 ! cardiac septum development GO:0003279 57 57 4.000 3.9E-03 0.07072515 0.47688477 1.000 0.881 ! negative regulation of peptidase activity GO:0010466 136 133 6.000 4.02E-03 0.07232694 0.78022202 1.000 0.946 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 58 58 4.000 4.152E-03 0.07411812 4.152E-03 0.47065004 0.764 ! regulation of carbohydrate catabolic process GO:0043470 29 29 3.000 4.169E-03 0.07382986 0.04214974 1.000 0.816 GO:0043471|regulation of cellular carbohydrate catabolic process, ! regulation of cellular carbohydrate catabolic process GO:0043471 29 29 3.000 4.169E-03 0.07382986 0.04214974 1.000 0.816 GO:0043470|regulation of carbohydrate catabolic process, ! odontogenesis GO:0042476 94 94 5.000 4.247E-03 0.07464217 0.28678092 1.000 0.946 ! negative regulation of immune system process GO:0002683 182 180 7.000 4.399E-03 0.07670434 0.60536654 1.000 0.946 ! regulation of cysteine-type endopeptidase activity GO:2000116 181 180 7.000 4.399E-03 0.07611881 0.60536654 1.000 0.946 ! negative regulation of intracellular protein transport GO:0090317 59 59 4.000 4.415E-03 0.07583241 0.48866305 1.000 0.860 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 30 30 3.000 4.594E-03 0.07829988 4.594E-03 0.49589927 0.689 ! negative regulation of cell growth GO:0030308 137 137 6.000 4.644E-03 0.07856584 0.79004918 1.000 0.946 ! positive regulation of cell division GO:0051781 61 60 4.000 4.69E-03 0.07875372 0.49445285 1.000 0.840 ! neuron migration GO:0001764 97 97 5.000 4.854E-03 0.08090677 0.09698383 1.000 0.946 ! regulation of carbohydrate biosynthetic process GO:0043255 61 61 4.000 4.975E-03 0.08232913 1.000 1.000 0.875 ! negative regulation of lipid biosynthetic process GO:0051055 31 31 3.000 5.044E-03 0.08286146 1.000 1.000 0.854 ! negative regulation of protein transport GO:0051224 101 100 5.000 5.519E-03 0.09001204 0.31179513 1.000 0.946 ! regulation of polysaccharide biosynthetic process GO:0032885 32 32 3.000 5.52E-03 0.08938669 1.000 1.000 0.841 ! cell differentiation involved in kidney development GO:0061005 32 32 3.000 5.52E-03 0.08875274 1.000 1.000 0.872 ! negative regulation of locomotion GO:0040013 143 142 6.000 5.521E-03 0.08814058 0.80172042 1.000 0.946 ! negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 64 63 4.000 5.581E-03 0.08847552 1.000 1.000 0.857 ! response to amino acid stimulus GO:0043200 66 63 4.000 5.581E-03 0.08786111 0.03430273 1.000 0.851 ! cell junction assembly GO:0034329 144 144 6.000 5.904E-03 0.09229982 0.02378745 1.000 0.946 ! cellular response to biotic stimulus GO:0071216 102 102 5.000 5.997E-03 0.09311574 0.68681712 1.000 0.891 ! regulation of vasodilation GO:0042312 33 33 3.000 6.022E-03 0.09287429 1.000 1.000 0.861 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 33 33 3.000 6.022E-03 0.09224676 0.3126266 1.000 0.845 ! negative regulation of growth GO:0045926 191 191 7.000 6.052E-03 0.09208617 0.63763761 1.000 0.946 ! glycosaminoglycan metabolic process GO:0030203 145 145 6.000 6.102E-03 0.09222209 6.102E-03 0.628787 0.946 ! negative regulation of intracellular transport GO:0032387 65 65 4.000 6.234E-03 0.09359079 0.52243782 1.000 0.868 ! negative regulation of protein modification process GO:0031400 193 193 7.000 6.397E-03 0.09540986 0.88946198 1.000 0.946 ! pattern recognition receptor signaling pathway GO:0002221 104 104 5.000 6.503E-03 0.09635633 0.32837339 1.000 0.946 ! cholesterol metabolic process GO:0008203 104 104 5.000 6.503E-03 0.09573063 0.1133346 1.000 0.946 ! positive regulation of gliogenesis GO:0014015 35 34 3.000 6.551E-03 0.09581194 0.32039831 1.000 0.852 ! positive regulation of mitosis GO:0045840 34 34 3.000 6.551E-03 0.09519776 1.000 1.000 0.837 GO:0051785|positive regulation of nuclear division, ! positive regulation of nuclear division GO:0051785 34 34 3.000 6.551E-03 0.09519776 1.000 1.000 0.837 GO:0045840|positive regulation of mitosis, ! cellular response to carbohydrate stimulus GO:0071322 34 34 3.000 6.551E-03 0.0945914 1.000 1.000 0.836 ! response to lipopolysaccharide GO:0032496 195 195 7.000 6.756E-03 0.09693971 1.000 1.000 0.946 ! negative regulation of cysteine-type endopeptidase activity GO:2000117 68 67 4.000 6.936E-03 0.09888806 1.000 1.000 0.862 ! regulation of polysaccharide metabolic process GO:0032881 35 35 3.000 7.106E-03 0.10068683 1.000 1.000 0.851 ! cellular response to amino acid stimulus GO:0071230 38 35 3.000 7.106E-03 0.10006145 7.106E-03 0.67124556 0.711 ! toll-like receptor 1 signaling pathway GO:0034130 68 68 4.000 7.305E-03 0.10223023 0.1789032 1.000 0.860 ! innate immune response-activating signal transduction GO:0002758 108 108 5.000 7.604E-03 0.10575821 0.34484336 1.000 0.946 ! toll-like receptor 2 signaling pathway GO:0034134 69 69 4.000 7.688E-03 0.10627035 0.18295657 1.000 0.862 ! monosaccharide biosynthetic process GO:0046364 69 69 4.000 7.688E-03 0.10562629 0.04311543 1.000 0.871 ! negative regulation of inflammatory response GO:0050728 70 69 4.000 7.688E-03 0.10498999 0.18295657 1.000 0.883 ! negative regulation of blood coagulation GO:0030195 36 36 3.000 7.689E-03 0.10437345 1.000 1.000 0.796 GO:1900047|negative regulation of hemostasis, ! endocrine process GO:0050886 36 36 3.000 7.689E-03 0.10375218 1.000 1.000 0.857 ! negative regulation of hemostasis GO:1900047 36 36 3.000 7.689E-03 0.10437345 1.000 1.000 0.796 GO:0030195|negative regulation of blood coagulation, ! cellular carbohydrate biosynthetic process GO:0034637 109 109 5.000 7.898E-03 0.10595158 0.03504634 1.000 0.946 ! erythrocyte homeostasis GO:0034101 70 70 4.000 8.083E-03 0.10779249 1.000 1.000 0.858 ! positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO:0090100 70 70 4.000 8.083E-03 0.10716212 0.18702341 1.000 0.883 ! aminoglycan metabolic process GO:0006022 154 154 6.000 8.113E-03 0.10692584 8.113E-03 0.73564977 0.946 ! sterol metabolic process GO:0016125 110 110 5.000 8.201E-03 0.10746125 0.12812037 1.000 0.946 ! positive regulation of cell cycle GO:0045787 111 110 5.000 8.201E-03 0.10684365 1.000 1.000 0.946 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 37 37 3.000 8.299E-03 0.10750251 1.000 1.000 0.863 ! positive regulation of cell development GO:0010720 156 155 6.000 8.362E-03 0.10771019 0.82913145 1.000 0.946 ! lipid transport GO:0006869 156 156 6.000 8.617E-03 0.11036804 0.83107664 1.000 0.946 ! negative regulation of protein phosphorylation GO:0001933 72 72 4.000 8.914E-03 0.11352295 0.55904551 1.000 0.880 ! sprouting angiogenesis GO:0002040 38 38 3.000 8.936E-03 0.11317448 0.06836472 1.000 0.822 ! MyD88-dependent toll-like receptor signaling pathway GO:0002755 73 73 4.000 9.349E-03 0.11774344 0.1992967 1.000 0.861 ! response to reactive oxygen species GO:0000302 114 114 5.000 9.49E-03 0.11885482 0.36929559 1.000 0.946 ! negative regulation of coagulation GO:0050819 39 39 3.000 9.602E-03 0.11959792 1.000 1.000 0.796 ! negative regulation of kinase activity GO:0033673 160 160 6.000 9.693E-03 0.12008002 0.03520631 1.000 0.946 ! regulation of endothelial cell migration GO:0010594 74 74 4.000 9.798E-03 0.12071419 1.000 1.000 0.886 ! activation of innate immune response GO:0002218 116 116 5.000 0.01018351 0.12478922 0.3773687 1.000 0.946 ! reactive oxygen species metabolic process GO:0072593 75 75 4.000 0.01026035 0.12505495 0.57386666 1.000 0.871 ! regulation of blood vessel endothelial cell migration GO:0043535 40 40 3.000 0.01029521 0.12480876 1.000 1.000 0.860 ! labyrinthine layer development GO:0060711 40 40 3.000 0.01029521 0.12414489 0.36522623 1.000 0.777 ! myelination GO:0042552 78 76 4.000 0.01073692 0.1287862 0.01073692 0.86930687 0.862 ! regulation of nitric oxide biosynthetic process GO:0045428 41 41 3.000 0.01101719 0.13145248 0.37240605 1.000 0.873 ! cellular response to acid GO:0071229 44 41 3.000 0.01101719 0.13076425 0.01101719 0.86124038 0.745 ! heart process GO:0003015 42 42 3.000 0.01176774 0.13894513 0.37950505 1.000 0.847 GO:0060047|heart contraction, ! heart contraction GO:0060047 42 42 3.000 0.01176774 0.13894513 0.37950505 1.000 0.847 GO:0003015|heart process, ! negative regulation of intracellular protein kinase cascade GO:0010741 121 121 5.000 0.0120691 0.14176498 0.0483138 1.000 0.946 ! ensheathment of neurons GO:0007272 81 79 4.000 0.01225163 0.14316724 0.01225163 0.86795137 0.859 GO:0008366|axon ensheathment, ! axon ensheathment GO:0008366 81 79 4.000 0.01225163 0.14316724 0.01225163 0.86795137 0.859 GO:0007272|ensheathment of neurons, ! cellular response to metal ion GO:0071248 79 79 4.000 0.01225163 0.14243305 0.59285985 1.000 0.876 ! cell junction organization GO:0034330 169 169 6.000 0.01245906 0.1441056 0.0428965 1.000 0.946 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO:0090092 169 169 6.000 0.01245906 0.1433741 0.29795732 1.000 0.946 ! Toll signaling pathway GO:0008063 80 80 4.000 0.01278535 0.14638575 0.2282615 1.000 0.869 ! transforming growth factor beta receptor signaling pathway GO:0007179 123 123 5.000 0.0128855 0.14679105 0.40527446 1.000 0.946 ! striated muscle cell differentiation GO:0051146 172 171 6.000 0.01314185 0.14896284 0.57738861 1.000 0.946 ! response to estrogen stimulus GO:0043627 124 124 5.000 0.01330737 0.1500886 0.75640543 1.000 0.946 ! peptidyl-serine modification GO:0018209 81 81 4.000 0.01333369 0.14964101 0.60203813 1.000 0.858 ! rhythmic process GO:0048511 173 173 6.000 0.01385045 0.15467473 0.58372847 1.000 0.946 ! embryonic placenta development GO:0001892 82 82 4.000 0.0138968 0.15443165 0.60654976 1.000 0.869 ! toll-like receptor 4 signaling pathway GO:0034142 82 82 4.000 0.0138968 0.15367833 0.23659576 1.000 0.870 ! glomerulus development GO:0032835 45 45 3.000 0.01419248 0.15618618 1.000 1.000 0.866 ! regulation of skeletal muscle fiber development GO:0048742 46 45 3.000 0.01419248 0.15543166 1.000 1.000 0.850 ! regulation of leukocyte apoptosis GO:2000106 45 45 3.000 0.01419248 0.15468439 1.000 1.000 0.875 ! aging GO:0007568 174 174 6.000 0.01421458 0.15418396 0.58687216 1.000 0.946 ! vascular process in circulatory system GO:0003018 83 83 4.000 0.0144748 0.15625896 1.000 1.000 0.889 ! regulation of protein secretion GO:0050708 128 127 5.000 0.01462872 0.15717204 0.76461669 1.000 0.946 ! regulation of glial cell differentiation GO:0045685 47 46 3.000 0.0150589 0.16103083 0.40711089 1.000 0.873 ! icosanoid biosynthetic process GO:0046456 46 46 3.000 0.0150589 0.16027482 0.09501449 1.000 0.789 ! negative regulation of defense response GO:0031348 85 84 4.000 0.01506781 0.15962026 0.2449464 1.000 0.887 ! regulation of cytokine-mediated signaling pathway GO:0001959 85 85 4.000 0.01567595 0.16529016 1.000 1.000 0.946 ! tissue remodeling GO:0048771 85 85 4.000 0.01567595 0.16452493 0.61978156 1.000 0.887 ! elevation of cytosolic calcium ion concentration GO:0007204 130 130 5.000 0.01603537 0.16752162 0.43257232 1.000 0.946 ! cardiac cell differentiation GO:0035051 87 86 4.000 0.01629933 0.16949811 1.000 1.000 0.890 ! ovulation cycle GO:0042698 86 86 4.000 0.01629933 0.16872415 1.000 1.000 0.881 ! actomyosin structure organization GO:0031032 49 48 3.000 0.01687971 0.1739377 0.42045199 1.000 0.742 ! response to acid GO:0001101 90 87 4.000 0.01693807 0.1737493 0.07549309 1.000 0.876 ! cellular response to lipopolysaccharide GO:0071222 87 87 4.000 0.01693807 0.17296665 1.000 1.000 0.890 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 182 182 6.000 0.01737087 0.17659087 0.33806552 1.000 0.946 ! outflow tract morphogenesis GO:0003151 49 49 3.000 0.01783426 0.18049224 1.000 1.000 0.887 ! cellular response to amine stimulus GO:0071418 52 49 3.000 0.01783426 0.17969005 0.01783426 1.000 0.819 ! cellular response to inorganic substance GO:0071241 89 89 4.000 0.01826201 0.18318572 0.63673763 1.000 0.882 ! cellular response to organic nitrogen GO:0071417 53 50 3.000 0.01881833 0.18793464 0.01881833 1.000 0.824 ! stem cell maintenance GO:0019827 90 90 4.000 0.01894742 0.18839383 0.27004864 1.000 0.946 ! positive regulation of MAP kinase activity GO:0043406 188 187 6.000 0.01957138 0.19374815 0.62614685 1.000 0.946 ! regulation of response to cytokine stimulus GO:0060759 91 91 4.000 0.01964858 0.19366663 1.000 1.000 0.946 ! positive regulation of endothelial cell proliferation GO:0001938 51 51 3.000 0.01983198 0.19462817 0.43990559 1.000 0.854 ! unsaturated fatty acid biosynthetic process GO:0006636 51 51 3.000 0.01983198 0.19378926 0.11293258 1.000 0.782 ! skin development GO:0043588 51 51 3.000 0.01983198 0.19295755 0.01983198 1.000 0.811 ! epithelial cell proliferation GO:0050673 51 51 3.000 0.01983198 0.19213294 0.43990559 1.000 0.854 ! regulation of morphogenesis of a branching structure GO:0060688 51 51 3.000 0.01983198 0.19131535 0.43990559 1.000 0.880 ! negative regulation of cytokine production GO:0001818 139 138 5.000 0.02021941 0.1942263 1.000 1.000 0.946 ! toll-like receptor signaling pathway GO:0002224 92 92 4.000 0.02036558 0.19480493 0.27841784 1.000 0.946 ! cellular response to molecule of bacterial origin GO:0071219 92 92 4.000 0.02036558 0.19398642 1.000 1.000 0.890 ! regulation of activin receptor signaling pathway GO:0032925 20 20 2.000 0.02106987 0.19985519 0.20317125 1.000 0.791 ! response to copper ion GO:0046688 20 20 2.000 0.02106987 0.19902246 0.20317125 1.000 0.781 ! cartilage development involved in endochondral bone morphogenesis GO:0060351 20 20 2.000 0.02106987 0.19819664 0.20317125 1.000 0.736 ! lymphocyte migration GO:0072676 20 20 2.000 0.02106987 0.19737765 0.20317125 1.000 0.757 ! striated muscle cell development GO:0055002 94 93 4.000 0.02109851 0.19683258 0.65294111 1.000 0.946 ! hexose biosynthetic process GO:0019319 53 53 3.000 0.02194814 0.20391979 0.1203273 1.000 0.846 ! negative regulation of nucleocytoplasmic transport GO:0046823 53 53 3.000 0.02194814 0.20308747 0.45251226 1.000 0.845 ! regulation of action potential GO:0001508 143 141 5.000 0.02195628 0.20233695 0.07575317 1.000 0.946 ! calcium ion transport GO:0006816 141 141 5.000 0.02195628 0.20151777 0.21335032 1.000 0.946 ! muscle contraction GO:0006936 194 193 6.000 0.02245402 0.20525513 0.1745589 1.000 0.946 ! regulation of action potential in neuron GO:0019228 97 95 4.000 0.02261247 0.20587339 0.02261247 1.000 0.946 ! stem cell development GO:0048864 95 95 4.000 0.02261247 0.2050499 0.29095893 1.000 0.946 ! aspartate family amino acid biosynthetic process GO:0009067 21 21 2.000 0.0231171 0.20879066 0.21217395 1.000 0.744 ! cyclic nucleotide biosynthetic process GO:0009190 21 21 2.000 0.0231171 0.20796212 1.000 1.000 0.747 ! entry into host cell GO:0030260 21 21 2.000 0.0231171 0.20714014 0.21217395 1.000 0.742 GO:0044409|entry into host, GO:0051806|entry into cell of other organism involved in symbiotic interaction, GO:0051828|entry into other organism involved in symbiotic interaction, GO:0052192|movement in environment of other organism involved in symbiotic interaction, GO:0052126|movement in host environment, ! neuron projection regeneration GO:0031102 21 21 2.000 0.0231171 0.20632463 1.000 1.000 0.702 ! regulation of renal sodium excretion GO:0035813 21 21 2.000 0.0231171 0.20551551 1.000 1.000 0.826 ! aorta development GO:0035904 21 21 2.000 0.0231171 0.20471272 1.000 1.000 0.848 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 21 21 2.000 0.0231171 0.20391617 0.21217395 1.000 0.716 ! entry into host GO:0044409 21 21 2.000 0.0231171 0.20714014 0.21217395 1.000 0.742 GO:0051806|entry into cell of other organism involved in symbiotic interaction, GO:0051828|entry into other organism involved in symbiotic interaction, GO:0052192|movement in environment of other organism involved in symbiotic interaction, GO:0030260|entry into host cell, GO:0052126|movement in host environment, ! positive regulation of striated muscle cell differentiation GO:0051155 21 21 2.000 0.0231171 0.2031258 0.21217395 1.000 0.779 ! entry into cell of other organism involved in symbiotic interaction GO:0051806 21 21 2.000 0.0231171 0.20714014 0.21217395 1.000 0.742 GO:0044409|entry into host, GO:0051828|entry into other organism involved in symbiotic interaction, GO:0052192|movement in environment of other organism involved in symbiotic interaction, GO:0030260|entry into host cell, GO:0052126|movement in host environment, ! entry into other organism involved in symbiotic interaction GO:0051828 21 21 2.000 0.0231171 0.20714014 0.21217395 1.000 0.742 GO:0044409|entry into host, GO:0051806|entry into cell of other organism involved in symbiotic interaction, GO:0052192|movement in environment of other organism involved in symbiotic interaction, GO:0030260|entry into host cell, GO:0052126|movement in host environment, ! movement in host environment GO:0052126 21 21 2.000 0.0231171 0.20714014 0.21217395 1.000 0.742 GO:0044409|entry into host, GO:0051806|entry into cell of other organism involved in symbiotic interaction, GO:0051828|entry into other organism involved in symbiotic interaction, GO:0052192|movement in environment of other organism involved in symbiotic interaction, GO:0030260|entry into host cell, ! movement in environment of other organism involved in symbiotic interaction GO:0052192 21 21 2.000 0.0231171 0.20714014 0.21217395 1.000 0.742 GO:0044409|entry into host, GO:0051806|entry into cell of other organism involved in symbiotic interaction, GO:0051828|entry into other organism involved in symbiotic interaction, GO:0030260|entry into host cell, GO:0052126|movement in host environment, ! blood coagulation, fibrin clot formation GO:0072378 21 21 2.000 0.0231171 0.20234153 0.0231171 1.000 0.576 ! regulation of stem cell differentiation GO:2000736 21 21 2.000 0.0231171 0.20156329 0.21217395 1.000 0.811 ! response to vitamin GO:0033273 143 143 5.000 0.02316648 0.20121996 0.48142692 1.000 0.946 ! hexose metabolic process GO:0019318 195 195 6.000 0.02347523 0.2031235 0.17900495 1.000 0.946 ! positive regulation of innate immune response GO:0045089 144 144 5.000 0.02378745 0.20504237 0.48507822 1.000 0.946 ! cytosolic calcium ion homeostasis GO:0051480 144 144 5.000 0.02378745 0.20426569 0.48507822 1.000 0.946 ! regulation of ion homeostasis GO:2000021 146 144 5.000 0.02378745 0.20349488 0.80620606 1.000 0.946 ! negative regulation of angiogenesis GO:0016525 55 55 3.000 0.02418284 0.20609966 0.46483656 1.000 0.808 ! endothelial cell development GO:0001885 22 22 2.000 0.02524264 0.21432606 0.02524264 1.000 0.740 ! regulation of natural killer cell activation GO:0032814 22 22 2.000 0.02524264 0.21352633 1.000 1.000 0.791 ! renal tubule morphogenesis GO:0061333 22 22 2.000 0.02524264 0.21273256 1.000 1.000 0.845 ! cellular response to cAMP GO:0071320 22 22 2.000 0.02524264 0.21194466 0.02524264 1.000 0.806 ! negative regulation of leukocyte proliferation GO:0070664 56 56 3.000 0.02534464 0.21201584 0.13163403 1.000 0.866 ! immune response-activating signal transduction GO:0002757 199 199 6.000 0.02561031 0.21345063 0.65978888 1.000 0.946 ! homeostasis of number of cells GO:0048872 148 147 5.000 0.0257145 0.21353396 1.000 1.000 0.946 ! hormone secretion GO:0046879 58 57 3.000 0.02653602 0.21955169 1.000 1.000 0.853 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 100 100 4.000 0.02668136 0.21995143 0.02668136 1.000 0.946 ! negative regulation of protein kinase activity GO:0006469 149 149 5.000 0.0270532 0.22220872 0.08852419 1.000 0.946 ! xenobiotic metabolic process GO:0006805 149 149 5.000 0.0270532 0.22140653 0.08852419 1.000 0.946 ! heparan sulfate proteoglycan metabolic process GO:0030201 23 23 2.000 0.02744448 0.22380087 0.02744448 1.000 0.686 ! regulation of excretion GO:0044062 23 23 2.000 0.02744448 0.22299872 1.000 1.000 0.834 ! negative regulation of cytokine secretion GO:0050710 24 23 2.000 0.02744448 0.22220229 0.22987685 1.000 0.795 ! positive regulation of positive chemotaxis GO:0050927 23 23 2.000 0.02744448 0.22141154 1.000 1.000 0.770 ! trabecula formation GO:0060343 23 23 2.000 0.02744448 0.22062639 0.02744448 1.000 0.812 ! cellular response to xenobiotic stimulus GO:0071466 150 150 5.000 0.02773891 0.2222053 0.09018954 1.000 0.946 ! cellular modified amino acid metabolic process GO:0006575 152 151 5.000 0.02843558 0.226984 0.02843558 1.000 0.946 ! body fluid secretion GO:0007589 59 59 3.000 0.0290074 0.23073602 1.000 1.000 0.868 ! muscle tissue morphogenesis GO:0060415 59 59 3.000 0.0290074 0.22992925 0.48866305 1.000 0.880 ! response to xenobiotic stimulus GO:0009410 152 152 5.000 0.02914326 0.23020132 0.09356524 1.000 0.946 ! heart valve morphogenesis GO:0003179 24 24 2.000 0.02972066 0.23394698 1.000 1.000 0.855 ! response to lithium ion GO:0010226 24 24 2.000 0.02972066 0.23313748 0.2385793 1.000 0.782 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 24 24 2.000 0.02972066 0.23233355 1.000 1.000 0.773 ! regulation of protein export from nucleus GO:0046825 24 24 2.000 0.02972066 0.23153516 1.000 1.000 0.733 ! regulation of positive chemotaxis GO:0050926 24 24 2.000 0.02972066 0.23074223 1.000 1.000 0.774 ! establishment of protein localization in plasma membrane GO:0090002 24 24 2.000 0.02972066 0.22995471 0.2385793 1.000 0.735 ! regulation of lymphocyte differentiation GO:0045619 105 104 4.000 0.03023254 0.23311963 1.000 1.000 0.946 ! positive regulation of calcium ion transport GO:0051928 60 60 3.000 0.03028727 0.23274997 0.49445285 1.000 0.879 ! kidney epithelium development GO:0072073 60 60 3.000 0.03028727 0.23196365 1.000 1.000 0.890 ! regulation of leukocyte proliferation GO:0070663 154 154 5.000 0.03059185 0.23350751 0.52070118 1.000 0.946 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 105 105 4.000 0.03116186 0.23706023 0.33250197 1.000 0.794 ! response to amine stimulus GO:0014075 108 105 4.000 0.03116186 0.23626738 0.11575144 1.000 0.946 ! alcohol biosynthetic process GO:0046165 105 105 4.000 0.03116186 0.23547983 0.11575144 1.000 0.946 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 106 105 4.000 0.03116186 0.2346975 0.69736121 1.000 0.891 ! hormone transport GO:0009914 62 61 3.000 0.03159651 0.23718305 1.000 1.000 0.856 ! regulation of blood coagulation GO:0030193 61 61 3.000 0.03159651 0.23640027 1.000 1.000 0.872 GO:1900046|regulation of hemostasis, ! regulation of skeletal muscle tissue development GO:0048641 62 61 3.000 0.03159651 0.23562264 1.000 1.000 0.875 ! regulation of hemostasis GO:1900046 61 61 3.000 0.03159651 0.23640027 1.000 1.000 0.872 GO:0030193|regulation of blood coagulation, ! Schwann cell differentiation GO:0014037 25 25 2.000 0.03206922 0.23836369 0.03206922 1.000 0.736 ! regulation of skeletal muscle cell differentiation GO:2001014 25 25 2.000 0.03206922 0.23758472 0.24718388 1.000 0.746 ! response to endoplasmic reticulum stress GO:0034976 106 106 4.000 0.03210788 0.23709627 0.03210788 1.000 0.946 ! cardiac ventricle morphogenesis GO:0003208 62 62 3.000 0.03293503 0.24241462 0.50583748 1.000 0.885 ! regulation of gliogenesis GO:0014013 63 62 3.000 0.03293503 0.2416301 0.50583748 1.000 0.884 ! carbohydrate homeostasis GO:0033500 108 108 4.000 0.03405009 0.24900499 1.000 1.000 0.946 GO:0042593|glucose homeostasis, ! glucose homeostasis GO:0042593 108 108 4.000 0.03405009 0.24900499 1.000 1.000 0.946 GO:0033500|carbohydrate homeostasis, ! alcohol catabolic process GO:0046164 108 108 4.000 0.03405009 0.24820433 0.12311705 1.000 0.946 ! peptidyl-tyrosine phosphorylation GO:0018108 63 63 3.000 0.03430273 0.24924451 0.51143375 1.000 0.863 ! erythrocyte differentiation GO:0030218 63 63 3.000 0.03430273 0.2484482 1.000 1.000 0.850 ! inactivation of MAPK activity GO:0000188 26 26 2.000 0.03448827 0.24899651 0.03448827 1.000 0.496 ! negative regulation of cytokine-mediated signaling pathway GO:0001960 26 26 2.000 0.03448827 0.24820605 1.000 1.000 0.812 ! regulation of S phase of mitotic cell cycle GO:0007090 26 26 2.000 0.03448827 0.24742059 1.000 1.000 0.667 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 26 26 2.000 0.03448827 0.24664008 0.25569171 1.000 0.818 ! negative regulation of interferon-gamma production GO:0032689 26 26 2.000 0.03448827 0.24586448 1.000 1.000 0.854 ! substrate adhesion-dependent cell spreading GO:0034446 26 26 2.000 0.03448827 0.24509375 0.25569171 1.000 0.695 ! negative regulation of cytokine biosynthetic process GO:0042036 26 26 2.000 0.03448827 0.24432783 0.25569171 1.000 0.783 ! regulation of endocrine process GO:0044060 26 26 2.000 0.03448827 0.24356668 1.000 1.000 0.841 ! regulation of focal adhesion assembly GO:0051893 26 26 2.000 0.03448827 0.24281027 1.000 1.000 0.824 GO:0090109|regulation of cell-substrate junction assembly, ! positive regulation of protein tyrosine kinase activity GO:0061098 26 26 2.000 0.03448827 0.24205853 1.000 1.000 0.802 ! regulation of cell-substrate junction assembly GO:0090109 26 26 2.000 0.03448827 0.24281027 1.000 1.000 0.824 GO:0051893|regulation of focal adhesion assembly, ! establishment of protein localization in membrane GO:0090150 26 26 2.000 0.03448827 0.24131144 0.25569171 1.000 0.752 ! purine nucleotide biosynthetic process GO:0006164 110 109 4.000 0.03504634 0.2444617 0.71087248 1.000 0.946 ! positive regulation of cell cycle process GO:0090068 161 160 5.000 0.03520631 0.24482423 1.000 1.000 0.946 ! response to lipid GO:0033993 64 64 3.000 0.03569952 0.24749481 1.000 1.000 0.884 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 64 64 3.000 0.03569952 0.24674025 0.16284135 1.000 0.699 ! cell projection assembly GO:0030031 162 162 5.000 0.03683499 0.25381435 0.27646465 1.000 0.946 ! regulation of macrophage derived foam cell differentiation GO:0010743 27 27 2.000 0.03697593 0.2540134 1.000 1.000 0.839 ! protein kinase B signaling cascade GO:0043491 27 27 2.000 0.03697593 0.25324599 1.000 1.000 0.815 ! positive regulation of receptor-mediated endocytosis GO:0048260 27 27 2.000 0.03697593 0.2524832 1.000 1.000 0.826 ! response to carbohydrate stimulus GO:0009743 111 111 4.000 0.03708924 0.25249644 0.7174013 1.000 0.946 ! peptidyl-tyrosine modification GO:0018212 65 65 3.000 0.03712527 0.25198501 0.52243782 1.000 0.865 ! muscle organ morphogenesis GO:0048644 65 65 3.000 0.03712527 0.25123281 0.52243782 1.000 0.881 ! icosanoid metabolic process GO:0006690 66 66 3.000 0.03857988 0.26029935 0.17084023 1.000 0.847 ! calcium-mediated signaling GO:0019722 67 66 3.000 0.03857988 0.25952695 0.52784701 1.000 0.851 ! regulation of BMP signaling pathway GO:0030510 66 66 3.000 0.03857988 0.25875911 0.52784701 1.000 0.863 ! regulation of coagulation GO:0050818 66 66 3.000 0.03857988 0.25799581 1.000 1.000 0.874 ! positive regulation of protein kinase B signaling cascade GO:0051897 66 66 3.000 0.03857988 0.257237 1.000 1.000 0.878 ! regulation of glycogen biosynthetic process GO:0005979 28 28 2.000 0.03953035 0.26280149 1.000 1.000 0.819 GO:0010962|regulation of glucan biosynthetic process, ! regulation of glucan biosynthetic process GO:0010962 28 28 2.000 0.03953035 0.26280149 1.000 1.000 0.819 GO:0005979|regulation of glycogen biosynthetic process, ! lamellipodium assembly GO:0030032 28 28 2.000 0.03953035 0.26203307 0.03953035 1.000 0.511 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 28 28 2.000 0.03953035 0.26126912 0.27242139 1.000 0.735 ! cardiac conduction GO:0061337 28 28 2.000 0.03953035 0.26050962 1.000 1.000 0.829 ! cellular response to monosaccharide stimulus GO:0071326 28 28 2.000 0.03953035 0.25975452 1.000 1.000 0.816 GO:0071333|cellular response to glucose stimulus, GO:0071331|cellular response to hexose stimulus, ! cellular response to hexose stimulus GO:0071331 28 28 2.000 0.03953035 0.25975452 1.000 1.000 0.816 GO:0071326|cellular response to monosaccharide stimulus, GO:0071333|cellular response to glucose stimulus, ! cellular response to glucose stimulus GO:0071333 28 28 2.000 0.03953035 0.25975452 1.000 1.000 0.816 GO:0071326|cellular response to monosaccharide stimulus, GO:0071331|cellular response to hexose stimulus, ! regulation of peptidyl-serine phosphorylation GO:0033135 68 67 3.000 0.0400632 0.262495 0.53319524 1.000 0.876 ! TRIF-dependent toll-like receptor signaling pathway GO:0035666 67 67 3.000 0.0400632 0.26173853 0.53319524 1.000 0.859 ! regulation of tumor necrosis factor production GO:0032680 68 68 3.000 0.0415751 0.27083548 1.000 1.000 0.889 ! regulation of systemic arterial blood pressure by hormone GO:0001990 29 29 2.000 0.04214974 0.27379216 1.000 1.000 0.835 ! positive regulation of fat cell differentiation GO:0045600 31 29 2.000 0.04214974 0.27300989 0.28064538 1.000 0.654 ! release of sequestered calcium ion into cytosol GO:0051209 29 29 2.000 0.04214974 0.27223209 0.28064538 1.000 0.833 GO:0051283|negative regulation of sequestering of calcium ion, ! negative regulation of sequestering of calcium ion GO:0051283 29 29 2.000 0.04214974 0.27223209 0.28064538 1.000 0.833 GO:0051209|release of sequestered calcium ion into cytosol, ! MyD88-independent toll-like receptor signaling pathway GO:0002756 69 69 3.000 0.04311543 0.27767805 0.54371151 1.000 0.860 ! peptidyl-serine phosphorylation GO:0018105 69 69 3.000 0.04311543 0.27689143 1.000 1.000 0.859 ! regulation of interferon-gamma production GO:0032649 70 69 3.000 0.04311543 0.27610925 1.000 1.000 0.889 ! regulation of interleukin-6 production GO:0032675 69 69 3.000 0.04311543 0.27533148 0.54371151 1.000 0.889 ! toll-like receptor 3 signaling pathway GO:0034138 69 69 3.000 0.04311543 0.27455807 0.54371151 1.000 0.862 ! divalent metal ion transport GO:0070838 170 170 5.000 0.0438086 0.27819073 0.30103709 1.000 0.946 ! response to estradiol stimulus GO:0032355 70 70 3.000 0.04468403 0.28295727 0.54888091 1.000 0.870 ! cellular response to reactive oxygen species GO:0034614 70 70 3.000 0.04468403 0.28216908 0.54888091 1.000 0.871 ! regulation of ion transmembrane transport GO:0034765 70 70 3.000 0.04468403 0.28138528 0.54888091 1.000 0.883 ! positive regulation of endocytosis GO:0045807 70 70 3.000 0.04468403 0.28060582 1.000 1.000 0.882 ! hemopoietic progenitor cell differentiation GO:0002244 30 30 2.000 0.04483232 0.28075929 1.000 1.000 0.819 ! negative regulation of ossification GO:0030279 30 30 2.000 0.04483232 0.27998584 0.28877686 1.000 0.806 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 30 2.000 0.04483232 0.27921665 1.000 1.000 0.860 ! negative regulation of fat cell differentiation GO:0045599 30 30 2.000 0.04483232 0.27845168 0.28877686 1.000 0.840 ! regulation of sequestering of calcium ion GO:0051282 30 30 2.000 0.04483232 0.27769088 0.28877686 1.000 0.837 ! negative regulation of response to cytokine stimulus GO:0060761 30 30 2.000 0.04483232 0.27693423 1.000 1.000 0.825 ! cellular response to transforming growth factor beta stimulus GO:0071560 30 30 2.000 0.04483232 0.27618169 0.04483232 1.000 0.810 ! phagocytosis GO:0006909 71 71 3.000 0.04628075 0.28433187 1.000 1.000 0.812 ! pancreas development GO:0031016 71 71 3.000 0.04628075 0.28356341 1.000 1.000 0.873 ! negative regulation of T cell activation GO:0050868 72 71 3.000 0.04628075 0.28279908 0.1911029 1.000 0.874 ! membrane depolarization GO:0051899 71 71 3.000 0.04628075 0.28203887 0.55399202 1.000 0.881 ! multicellular organismal homeostasis GO:0048871 120 120 4.000 0.04711563 0.28635694 0.15416238 1.000 0.946 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 174 174 5.000 0.04757313 0.28836437 0.13442824 1.000 0.946 ! divalent inorganic cation transport GO:0072511 174 174 5.000 0.04757313 0.2875954 0.31337086 1.000 0.946 ! actin polymerization or depolymerization GO:0008154 31 31 2.000 0.04757633 0.28684987 0.29681688 1.000 0.646 ! positive regulation of actin filament bundle assembly GO:0032233 31 31 2.000 0.04757633 0.28608899 0.29681688 1.000 0.773 ! tissue regeneration GO:0042246 31 31 2.000 0.04757633 0.28533214 0.29681688 1.000 0.709 ! calcium ion transmembrane transport GO:0070588 31 31 2.000 0.04757633 0.28457929 0.29681688 1.000 0.812 ! regulation of glycogen metabolic process GO:0070873 31 31 2.000 0.04757633 0.28383039 1.000 1.000 0.834 ! positive regulation of neural precursor cell proliferation GO:2000179 31 31 2.000 0.04757633 0.28308543 1.000 1.000 0.851 ! response to organic nitrogen GO:0010243 124 121 4.000 0.0483138 0.28672093 0.15685345 1.000 0.946 ! regulation of endothelial cell proliferation GO:0001936 73 73 3.000 0.04955783 0.29333579 0.56404202 1.000 0.878 ! response to cold GO:0009409 32 32 2.000 0.05038008 0.29742616 1.000 1.000 0.751 ! regulation of sterol transport GO:0032371 32 32 2.000 0.05038008 0.29665362 1.000 1.000 0.874 GO:0032374|regulation of cholesterol transport, ! regulation of cholesterol transport GO:0032374 32 32 2.000 0.05038008 0.29665362 1.000 1.000 0.874 GO:0032371|regulation of sterol transport, ! regulation of circadian rhythm GO:0042752 32 32 2.000 0.05038008 0.29588509 0.05038008 1.000 0.770 ! negative regulation of lymphocyte differentiation GO:0045620 33 32 2.000 0.05038008 0.29512053 1.000 1.000 0.855 ! trabecula morphogenesis GO:0061383 32 32 2.000 0.05038008 0.29435991 0.05038008 1.000 0.849 ! cellular response to lipid GO:0071396 32 32 2.000 0.05038008 0.2936032 1.000 1.000 0.844 ! nephron tubule development GO:0072080 32 32 2.000 0.05038008 0.29285037 1.000 1.000 0.872 ! metanephric nephron development GO:0072210 32 32 2.000 0.05038008 0.29210139 1.000 1.000 0.881 ! purine-containing compound biosynthetic process GO:0072522 124 123 4.000 0.05076046 0.29355604 0.75360549 1.000 0.946 ! ameboidal cell migration GO:0001667 75 75 3.000 0.05294523 0.30541182 0.05294523 1.000 0.878 ! positive regulation of hormone secretion GO:0046887 75 75 3.000 0.05294523 0.30463667 1.000 1.000 0.886 ! epithelial cell morphogenesis GO:0003382 33 33 2.000 0.05324187 0.30556792 0.05324187 1.000 0.835 ! ventral spinal cord development GO:0021517 33 33 2.000 0.05324187 0.30479629 1.000 1.000 0.784 ! regulation of S phase GO:0033261 33 33 2.000 0.05324187 0.30402854 1.000 1.000 0.713 ! regulation of erythrocyte differentiation GO:0045646 33 33 2.000 0.05324187 0.30326465 0.3126266 1.000 0.813 ! renal tubule development GO:0061326 33 33 2.000 0.05324187 0.30250459 1.000 1.000 0.874 ! response to transforming growth factor beta stimulus GO:0071559 33 33 2.000 0.05324187 0.30174832 0.05324187 1.000 0.828 ! negative regulation of secretion GO:0051048 126 125 4.000 0.05327404 0.30117765 0.75917371 1.000 0.946 ! regulation of metal ion transport GO:0010959 180 180 5.000 0.05356951 0.30209475 0.60536654 1.000 0.946 ! regulation of calcium ion transport GO:0051924 126 126 4.000 0.05455584 0.30689354 0.41705241 1.000 0.946 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 128 127 4.000 0.05585429 0.31341997 0.76461669 1.000 0.946 ! blood vessel remodeling GO:0001974 34 34 2.000 0.05616006 0.31435768 0.32039831 1.000 0.863 ! cell-substrate junction assembly GO:0007044 34 34 2.000 0.05616006 0.3135834 0.05616006 1.000 0.671 ! negative regulation of BMP signaling pathway GO:0030514 34 34 2.000 0.05616006 0.31281292 0.32039831 1.000 0.731 ! collagen metabolic process GO:0032963 34 34 2.000 0.05616006 0.31204622 0.05616006 1.000 0.474 ! cellular polysaccharide biosynthetic process GO:0033692 34 34 2.000 0.05616006 0.31128328 0.32039831 1.000 0.753 ! molting cycle GO:0042303 77 77 3.000 0.0564414 0.31207965 0.21580212 1.000 0.867 GO:0042633|hair cycle, ! hair cycle GO:0042633 77 77 3.000 0.0564414 0.31207965 0.21580212 1.000 0.867 GO:0042303|molting cycle, ! liver development GO:0001889 78 78 3.000 0.05822976 0.32118459 0.58819203 1.000 0.881 ! peripheral nervous system development GO:0007422 78 78 3.000 0.05822976 0.32040502 0.05822976 1.000 0.860 ! protein dephosphorylation GO:0006470 129 129 4.000 0.05850093 0.32111768 0.05850093 1.000 0.680 ! kidney development GO:0001822 185 185 5.000 0.05888763 0.32245955 1.000 1.000 0.946 ! carbohydrate catabolic process GO:0016052 185 185 5.000 0.05888763 0.32168254 0.15717711 1.000 0.946 ! embryonic axis specification GO:0000578 35 35 2.000 0.05913302 0.32224653 0.32808258 1.000 0.826 ! regulation of lipid storage GO:0010883 35 35 2.000 0.05913302 0.32147375 1.000 1.000 0.817 ! regulation of chondrocyte differentiation GO:0032330 35 35 2.000 0.05913302 0.32070468 0.32808258 1.000 0.797 ! sulfur compound catabolic process GO:0044273 35 35 2.000 0.05913302 0.31993927 0.05913302 1.000 0.719 ! negative regulation of blood pressure GO:0045776 35 35 2.000 0.05913302 0.31917751 0.32808258 1.000 0.866 ! cardiac muscle contraction GO:0060048 35 35 2.000 0.05913302 0.31841937 0.32808258 1.000 0.827 ! ossification GO:0001503 186 186 5.000 0.05998627 0.32224851 0.15931318 1.000 0.946 ! regulation of Wnt receptor signaling pathway GO:0030111 189 186 5.000 0.05998627 0.3214867 0.35040094 1.000 0.946 ! unsaturated fatty acid metabolic process GO:0033559 79 79 3.000 0.06004469 0.32104081 0.22410211 1.000 0.859 ! Ras protein signal transduction GO:0007265 131 131 4.000 0.06121362 0.32652065 0.18451824 1.000 0.946 ! ovulation cycle process GO:0022602 80 80 3.000 0.06188596 0.32933209 1.000 1.000 0.883 ! positive regulation of protein catabolic process GO:0045732 80 80 3.000 0.06188596 0.32856082 0.2282615 1.000 0.869 ! hepaticobiliary system development GO:0061008 80 80 3.000 0.06188596 0.32779316 0.59747502 1.000 0.883 ! nephron development GO:0072006 80 80 3.000 0.06188596 0.32702907 1.000 1.000 0.890 ! myofibril assembly GO:0030239 37 36 2.000 0.06215915 0.32770884 1.000 1.000 0.790 ! stem cell differentiation GO:0048863 132 132 4.000 0.06259462 0.32923899 0.44024988 1.000 0.946 ! positive regulation of mesenchymal cell proliferation GO:0002053 37 37 2.000 0.0652369 0.34234271 1.000 1.000 0.848 ! neutrophil chemotaxis GO:0030593 37 37 2.000 0.0652369 0.34155208 0.34319271 1.000 0.795 ! positive regulation of mitotic cell cycle GO:0045931 37 37 2.000 0.0652369 0.34076509 1.000 1.000 0.846 ! cardiac cell development GO:0055006 37 37 2.000 0.0652369 0.33998172 1.000 1.000 0.861 ! fat cell differentiation GO:0045444 82 82 3.000 0.06564664 0.34133242 0.60654976 1.000 0.946 ! germ cell development GO:0007281 135 135 4.000 0.06683561 0.3467193 0.45165922 1.000 0.946 ! monosaccharide catabolic process GO:0046365 83 83 3.000 0.06756559 0.34970589 0.24076934 1.000 0.865 ! regulation of B cell activation GO:0050864 83 83 3.000 0.06756559 0.3489093 1.000 1.000 0.887 ! renal system development GO:0072001 193 193 5.000 0.0680026 0.35036793 1.000 1.000 0.946 ! regulation of TOR signaling cascade GO:0032006 40 38 2.000 0.06836472 0.35143496 0.3506205 1.000 0.658 ! positive regulation of fibroblast proliferation GO:0048146 38 38 2.000 0.06836472 0.35063986 1.000 1.000 0.845 ! negative regulation of protein secretion GO:0050709 39 38 2.000 0.06836472 0.34984835 0.3506205 1.000 0.830 ! calcium ion transport into cytosol GO:0060402 38 38 2.000 0.06836472 0.3490604 0.3506205 1.000 0.844 ! activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 84 84 3.000 0.06950995 0.35411023 0.2449464 1.000 0.871 ! regulation of embryonic development GO:0045995 85 84 3.000 0.06950995 0.35331626 0.61542091 1.000 0.890 ! positive regulation of catabolic process GO:0009896 138 138 4.000 0.07122237 0.36121056 0.46293629 1.000 0.946 ! regulation of organ morphogenesis GO:2000027 138 138 4.000 0.07122237 0.36040428 1.000 1.000 0.946 ! polysaccharide catabolic process GO:0000272 85 85 3.000 0.07147948 0.36089975 0.24912633 1.000 0.946 ! activation of cysteine-type endopeptidase activity GO:0097202 85 85 3.000 0.07147948 0.36009775 0.24912633 1.000 0.871 ! cellular glucose homeostasis GO:0001678 39 39 2.000 0.0715411 0.35960905 1.000 1.000 0.850 ! cell fate determination GO:0001709 39 39 2.000 0.0715411 0.35881346 0.35796469 1.000 0.854 ! regulation of interleukin-1 production GO:0032652 39 39 2.000 0.0715411 0.35802137 1.000 1.000 0.866 ! termination of G-protein coupled receptor signaling pathway GO:0038032 39 39 2.000 0.0715411 0.35723278 0.0715411 1.000 0.119 ! regulation of receptor-mediated endocytosis GO:0048259 39 39 2.000 0.0715411 0.35644765 1.000 1.000 0.853 ! positive regulation of smooth muscle cell proliferation GO:0048661 39 39 2.000 0.0715411 0.35566597 1.000 1.000 0.868 ! regulation of stress fiber assembly GO:0051492 39 39 2.000 0.0715411 0.35488771 0.35796469 1.000 0.817 ! cytosolic calcium ion transport GO:0060401 39 39 2.000 0.0715411 0.35411284 0.35796469 1.000 0.848 ! cellular response to interleukin-1 GO:0071347 39 39 2.000 0.0715411 0.35334136 0.35796469 1.000 0.865 ! generation of a signal involved in cell-cell signaling GO:0003001 140 139 4.000 0.07271672 0.35836699 0.79479753 1.000 0.946 GO:0023061|signal release, ! signal release GO:0023061 140 139 4.000 0.07271672 0.35836699 0.79479753 1.000 0.946 GO:0003001|generation of a signal involved in cell-cell signaling, ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 86 3.000 0.07347395 0.36131331 0.62409301 1.000 0.723 ! cellular aldehyde metabolic process GO:0006081 40 40 2.000 0.07476457 0.36686425 0.36522623 1.000 0.829 ! aspartate family amino acid metabolic process GO:0009066 40 40 2.000 0.07476457 0.36607189 0.36522623 1.000 0.823 ! multicellular organismal macromolecule metabolic process GO:0044259 40 40 2.000 0.07476457 0.36528294 0.07476457 1.000 0.613 ! tissue homeostasis GO:0001894 87 87 3.000 0.07549309 0.36804909 0.25749242 1.000 0.876 ! lipid homeostasis GO:0055088 87 87 3.000 0.07549309 0.36725928 0.6283558 1.000 0.886 ! regulation of cyclic nucleotide biosynthetic process GO:0030802 142 142 4.000 0.07729511 0.37522058 1.000 1.000 0.946 ! regulation of mesenchymal cell proliferation GO:0010464 41 41 2.000 0.07803367 0.37799642 1.000 1.000 0.861 ! endothelial cell differentiation GO:0045446 41 41 2.000 0.07803367 0.37719046 0.07803367 1.000 0.838 ! nephron epithelium development GO:0072009 41 41 2.000 0.07803367 0.37638793 1.000 1.000 0.883 ! regulation of plasma lipoprotein particle levels GO:0097006 41 41 2.000 0.07803367 0.3755888 1.000 1.000 0.871 ! appendage development GO:0048736 143 143 4.000 0.07885277 0.37872717 1.000 1.000 0.946 GO:0060173|limb development, ! limb development GO:0060173 143 143 4.000 0.07885277 0.37872717 1.000 1.000 0.946 GO:0048736|appendage development, ! response to glucose stimulus GO:0009749 89 89 3.000 0.07960436 0.38152874 0.63673763 1.000 0.887 ! dorsal/ventral pattern formation GO:0009953 89 89 3.000 0.07960436 0.38072382 0.63673763 1.000 0.946 ! negative regulation of protein serine/threonine kinase activity GO:0071901 89 89 3.000 0.07960436 0.3799223 0.26586302 1.000 0.946 ! regulation of vasoconstriction GO:0019229 42 42 2.000 0.08134696 0.38742347 1.000 1.000 0.861 ! termination of signal transduction GO:0023021 42 42 2.000 0.08134696 0.38661126 0.08134696 1.000 0.241 ! negative regulation of T cell proliferation GO:0042130 42 42 2.000 0.08134696 0.38580245 0.08134696 1.000 0.852 ! regulation of mitosis GO:0007088 90 90 3.000 0.08169598 0.38664884 1.000 1.000 0.946 GO:0051783|regulation of nuclear division, ! regulation of nuclear division GO:0051783 90 90 3.000 0.08169598 0.38664884 1.000 1.000 0.946 GO:0007088|regulation of mitosis, ! regulation of protein kinase B signaling cascade GO:0051896 90 90 3.000 0.08169598 0.38584332 1.000 1.000 0.888 ! cellular component assembly involved in morphogenesis GO:0010927 147 145 4.000 0.08201491 0.3865443 0.48871363 1.000 0.946 ! dephosphorylation GO:0016311 145 145 4.000 0.08201491 0.38574234 0.08201491 1.000 0.751 ! regulation of nucleotide biosynthetic process GO:0030808 145 145 4.000 0.08201491 0.3849437 1.000 1.000 0.946 ! cartilage development GO:0051216 145 145 4.000 0.08201491 0.38414836 0.48871363 1.000 0.946 ! protein import into nucleus GO:0006606 91 91 3.000 0.08381124 0.39175272 0.64493133 1.000 0.946 ! positive regulation of ion transport GO:0043270 91 91 3.000 0.08381124 0.39094665 0.64493133 1.000 0.887 ! chondrocyte differentiation GO:0002062 43 43 2.000 0.08470306 0.39429535 0.38652415 1.000 0.852 ! cyclic nucleotide metabolic process GO:0009187 43 43 2.000 0.08470306 0.39348737 1.000 1.000 0.832 ! endochondral bone morphogenesis GO:0060350 43 43 2.000 0.08470306 0.39268269 0.38652415 1.000 0.832 ! regulation of protein processing GO:0070613 43 43 2.000 0.08470306 0.3918813 1.000 1.000 0.770 ! nucleoside monophosphate metabolic process GO:0009123 93 92 3.000 0.08594985 0.39683975 1.000 1.000 0.887 ! response to hexose stimulus GO:0009746 92 92 3.000 0.08594985 0.39603316 0.64895895 1.000 0.888 GO:0034284|response to monosaccharide stimulus, ! positive regulation of cyclic nucleotide biosynthetic process GO:0030804 92 92 3.000 0.08594985 0.39522985 1.000 1.000 0.946 ! response to monosaccharide stimulus GO:0034284 92 92 3.000 0.08594985 0.39603316 0.64895895 1.000 0.888 GO:0009746|response to hexose stimulus, ! myeloid cell differentiation GO:0030099 148 148 4.000 0.08687397 0.39867061 1.000 1.000 0.946 ! regulation of lymphocyte proliferation GO:0050670 148 148 4.000 0.08687397 0.39786521 0.4995235 1.000 0.946 ! ventricular cardiac muscle tissue development GO:0003229 44 44 2.000 0.08810057 0.40266936 0.39346423 1.000 0.865 ! gluconeogenesis GO:0006094 44 44 2.000 0.08810057 0.40185916 0.39346423 1.000 0.828 ! glycolysis GO:0006096 44 44 2.000 0.08810057 0.40105222 0.39346423 1.000 0.793 ! regulation of actin filament bundle assembly GO:0032231 44 44 2.000 0.08810057 0.4002485 0.39346423 1.000 0.833 ! exocrine system development GO:0035272 44 44 2.000 0.08810057 0.39944801 1.000 1.000 0.860 ! nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway GO:0035872 44 44 2.000 0.08810057 0.3986507 0.39346423 1.000 0.839 ! ureteric bud development GO:0001657 93 93 3.000 0.08811156 0.39790621 0.65294111 1.000 0.889 ! development of primary female sexual characteristics GO:0046545 93 93 3.000 0.08811156 0.39711514 0.65294111 1.000 0.946 ! regulation of cyclic nucleotide metabolic process GO:0030799 149 149 4.000 0.08852419 0.39818323 1.000 1.000 0.946 ! regulation of mononuclear cell proliferation GO:0032944 149 149 4.000 0.08852419 0.39739474 0.50309434 1.000 0.946 ! energy reserve metabolic process GO:0006112 150 150 4.000 0.09018954 0.40407054 0.24006424 1.000 0.946 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 94 94 3.000 0.0902961 0.40375 0.28678092 1.000 0.946 ! positive regulation of nucleotide biosynthetic process GO:0030810 94 94 3.000 0.0902961 0.40295521 1.000 1.000 0.946 ! nuclear import GO:0051170 94 94 3.000 0.0902961 0.40216355 0.65687831 1.000 0.946 ! Rho protein signal transduction GO:0007266 45 45 2.000 0.09153816 0.4068961 0.40032618 1.000 0.637 ! regulation of glucose import GO:0046324 46 45 2.000 0.09153816 0.40609982 1.000 1.000 0.838 ! kidney morphogenesis GO:0060993 45 45 2.000 0.09153816 0.40530666 1.000 1.000 0.881 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 95 95 3.000 0.09250317 0.40878107 1.000 1.000 0.946 ! regulation of lipid biosynthetic process GO:0046890 95 95 3.000 0.09250317 0.40798577 1.000 1.000 0.890 ! glucose metabolic process GO:0006006 152 152 4.000 0.09356524 0.41186873 0.51370824 1.000 0.946 ! receptor-mediated endocytosis GO:0006898 96 96 3.000 0.09473251 0.41619884 0.66461989 1.000 0.946 ! oligosaccharide biosynthetic process GO:0009312 46 46 2.000 0.09501449 0.41663027 0.40711089 1.000 0.701 ! negative regulation of protein import into nucleus GO:0042308 46 46 2.000 0.09501449 0.41582596 0.40711089 1.000 0.827 ! multicellular organismal metabolic process GO:0044236 46 46 2.000 0.09501449 0.41502476 0.09501449 1.000 0.690 ! regulation of protein tyrosine kinase activity GO:0061097 46 46 2.000 0.09501449 0.41422663 1.000 1.000 0.830 ! ovarian follicle development GO:0001541 47 47 2.000 0.09852826 0.42872087 1.000 1.000 0.831 ! peptide secretion GO:0002790 47 47 2.000 0.09852826 0.42789956 1.000 1.000 0.825 ! glycogen metabolic process GO:0005977 47 47 2.000 0.09852826 0.4270814 0.41381921 1.000 0.775 ! aerobic respiration GO:0009060 48 47 2.000 0.09852826 0.42626636 0.09852826 1.000 0.803 ! endothelial cell migration GO:0043542 47 47 2.000 0.09852826 0.42545442 0.41381921 1.000 0.822 ! negative regulation of hormone secretion GO:0046888 47 47 2.000 0.09852826 0.42464557 1.000 1.000 0.863 ! positive regulation of nucleotide metabolic process GO:0045981 98 98 3.000 0.09925685 0.42697398 1.000 1.000 0.946 ! response to starvation GO:0042594 100 99 3.000 0.10155129 0.43601662 0.67590754 1.000 0.946 ! endothelium development GO:0003158 48 48 2.000 0.1020782 0.43745043 0.1020782 1.000 0.851 ! endocrine pancreas development GO:0031018 48 48 2.000 0.1020782 0.43662506 1.000 1.000 0.838 ! positive regulation of carbohydrate metabolic process GO:0045913 49 48 2.000 0.1020782 0.43580279 1.000 1.000 0.872 ! autonomic nervous system development GO:0048483 48 48 2.000 0.1020782 0.43498361 1.000 1.000 0.869 ! regulation of cartilage development GO:0061035 48 48 2.000 0.1020782 0.4341675 0.42045199 1.000 0.848 ! lymphocyte differentiation GO:0030098 157 157 4.000 0.1022624 0.43413646 1.000 1.000 0.946 ! female sex differentiation GO:0046660 100 100 3.000 0.10386686 0.44012367 0.67958545 1.000 0.946 ! protein autophosphorylation GO:0046777 158 158 4.000 0.10404524 0.44005703 0.53448527 1.000 0.946 ! cellular glucan metabolic process GO:0006073 49 49 2.000 0.10566305 0.44606728 0.4270101 1.000 0.788 GO:0044042|glucan metabolic process, ! glucan metabolic process GO:0044042 49 49 2.000 0.10566305 0.44606728 0.4270101 1.000 0.788 GO:0006073|cellular glucan metabolic process, ! regulation of neural precursor cell proliferation GO:2000177 49 49 2.000 0.10566305 0.44523816 1.000 1.000 0.869 ! regulation of nucleocytoplasmic transport GO:0046822 159 159 4.000 0.10584231 0.44516607 0.83678098 1.000 0.946 ! cellular response to oxidative stress GO:0034599 101 101 3.000 0.10620326 0.44585702 0.68322182 1.000 0.946 ! positive regulation of cytoskeleton organization GO:0051495 102 101 3.000 0.10620326 0.44503288 0.68322182 1.000 0.946 ! intracellular receptor mediated signaling pathway GO:0030522 160 160 4.000 0.10765349 0.4502776 0.83863951 1.000 0.946 ! mesenchymal cell development GO:0014031 102 102 3.000 0.10856021 0.45323389 0.68681712 1.000 0.891 ! peptidyl-tyrosine dephosphorylation GO:0035335 50 50 2.000 0.10928158 0.45540687 0.10928158 1.000 0.404 ! positive regulation of DNA replication GO:0045740 50 50 2.000 0.10928158 0.45457126 1.000 1.000 0.870 ! response to temperature stimulus GO:0009266 103 103 3.000 0.11093742 0.46061381 0.69037182 1.000 0.946 ! nucleotide biosynthetic process GO:0009165 163 162 4.000 0.11131775 0.46134799 0.84229362 1.000 0.946 ! regulation of striated muscle tissue development GO:0016202 105 104 3.000 0.1133346 0.46884951 1.000 1.000 0.891 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 106 105 3.000 0.11575144 0.47797545 0.33250197 1.000 0.946 ! regulation of muscle organ development GO:0048634 106 105 3.000 0.11575144 0.4771064 1.000 1.000 0.946 ! long-chain fatty acid metabolic process GO:0001676 52 52 2.000 0.11661488 0.47979296 0.44624462 1.000 0.839 ! protein localization in plasma membrane GO:0072659 53 52 2.000 0.11661488 0.47892377 0.44624462 1.000 0.821 ! mesoderm development GO:0007498 106 106 3.000 0.11818766 0.4845053 0.70079681 1.000 0.946 ! ER to Golgi vesicle-mediated transport GO:0006888 53 53 2.000 0.1203273 0.49238625 0.1203273 1.000 0.466 ! negative regulation of mononuclear cell proliferation GO:0032945 53 53 2.000 0.1203273 0.49149907 0.1203273 1.000 0.860 GO:0050672|negative regulation of lymphocyte proliferation, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 54 53 2.000 0.1203273 0.49061508 1.000 1.000 0.857 ! negative regulation of neuron differentiation GO:0045665 53 53 2.000 0.1203273 0.48973426 0.45251226 1.000 0.835 ! oogenesis GO:0048477 53 53 2.000 0.1203273 0.4888566 0.45251226 1.000 0.807 ! negative regulation of lymphocyte proliferation GO:0050672 53 53 2.000 0.1203273 0.49149907 0.1203273 1.000 0.860 GO:0032945|negative regulation of mononuclear cell proliferation, ! cardiac muscle tissue morphogenesis GO:0055008 53 53 2.000 0.1203273 0.48798208 0.45251226 1.000 0.879 ! regulation of kidney development GO:0090183 53 53 2.000 0.1203273 0.48711068 1.000 1.000 0.885 ! cellular amino acid biosynthetic process GO:0008652 107 107 3.000 0.12064296 0.487518 0.34073731 1.000 0.946 ! regulation of T cell proliferation GO:0042129 107 107 3.000 0.12064296 0.48665053 0.34073731 1.000 0.892 ! positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 107 107 3.000 0.12064296 0.48578614 0.34073731 1.000 0.946 ! response to glucocorticoid stimulus GO:0051384 107 107 3.000 0.12064296 0.48492482 0.7041936 1.000 0.946 ! cellular response to extracellular stimulus GO:0031668 169 168 4.000 0.12263763 0.49206994 0.8527692 1.000 0.946 ! nucleic acid phosphodiester bond hydrolysis GO:0090305 55 54 2.000 0.12406871 0.49693243 0.45870931 1.000 0.818 ! actin filament-based movement GO:0030048 55 55 2.000 0.12783798 0.51112647 0.46483656 1.000 0.770 ! negative regulation of cellular catabolic process GO:0031330 55 55 2.000 0.12783798 0.5102266 0.12783798 1.000 0.852 ! protein polymerization GO:0051258 55 55 2.000 0.12783798 0.50932989 0.46483656 1.000 0.536 ! fatty acid biosynthetic process GO:0006633 110 110 3.000 0.12812037 0.50955942 0.35303046 1.000 0.946 ! positive regulation of cysteine-type endopeptidase activity GO:2001056 110 110 3.000 0.12812037 0.50866702 0.35303046 1.000 0.946 ! regulation of intracellular protein transport GO:0033157 174 171 4.000 0.12847574 0.50918619 0.85774434 1.000 0.946 ! cellular response to mechanical stimulus GO:0071260 56 56 2.000 0.13163403 0.52079294 0.47089479 1.000 0.854 ! regulation of muscle contraction GO:0006937 112 112 3.000 0.13319524 0.52605159 1.000 1.000 0.946 ! neural crest cell development GO:0014032 57 57 2.000 0.13545578 0.53404913 1.000 1.000 0.879 ! negative regulation of transmembrane transport GO:0034763 57 57 2.000 0.13545578 0.53312196 0.47688477 1.000 0.859 ! regulation of reactive oxygen species metabolic process GO:2000377 57 57 2.000 0.13545578 0.53219801 0.47688477 1.000 0.863 ! actin filament organization GO:0007015 113 113 3.000 0.13575876 0.5324656 0.36524373 1.000 0.946 ! response to corticosteroid stimulus GO:0031960 113 113 3.000 0.13575876 0.53154597 0.7237834 1.000 0.946 ! Notch signaling pathway GO:0007219 118 114 3.000 0.13833927 0.54071575 0.36929559 1.000 0.946 ! mesenchymal cell differentiation GO:0048762 114 114 3.000 0.13833927 0.53978509 0.72692046 1.000 0.946 ! signal transduction by p53 class mediator GO:0072331 115 114 3.000 0.13833927 0.53885762 0.36929559 1.000 0.946 ! glucose catabolic process GO:0006007 58 58 2.000 0.13930217 0.54167754 0.48280727 1.000 0.837 ! cell aging GO:0007569 58 58 2.000 0.13930217 0.54075001 0.48280727 1.000 0.868 ! peptide transport GO:0015833 58 58 2.000 0.13930217 0.53982566 1.000 1.000 0.841 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 58 58 2.000 0.13930217 0.53890445 0.48280727 1.000 0.833 ! regulation of alpha-beta T cell activation GO:0046634 58 58 2.000 0.13930217 0.53798639 0.48280727 1.000 0.887 ! ureteric bud morphogenesis GO:0060675 58 58 2.000 0.13930217 0.53707144 0.48280727 1.000 0.879 ! cellular response to vitamin GO:0071295 58 58 2.000 0.13930217 0.53615961 1.000 1.000 0.877 ! nucleobase-containing compound biosynthetic process GO:0034654 178 177 4.000 0.14049174 0.53982165 0.86719828 1.000 0.946 ! glial cell differentiation GO:0010001 117 115 3.000 0.14093648 0.54061421 0.37333734 1.000 0.946 ! positive regulation of endopeptidase activity GO:0010950 115 115 3.000 0.14093648 0.53970101 0.37333734 1.000 0.946 ! negative regulation of Wnt receptor signaling pathway GO:0030178 118 115 3.000 0.14093648 0.53879089 0.37333734 1.000 0.946 ! glycosaminoglycan catabolic process GO:0006027 59 59 2.000 0.14317216 0.5464163 0.14317216 1.000 0.772 ! striated muscle contraction GO:0006941 60 59 2.000 0.14317216 0.54549795 0.48866305 1.000 0.846 ! regulation of blood vessel size GO:0050880 59 59 2.000 0.14317216 0.54458269 1.000 1.000 0.880 ! cellular carbohydrate catabolic process GO:0044275 116 116 3.000 0.14355007 0.54510555 0.3773687 1.000 0.946 ! regulation of ERK1 and ERK2 cascade GO:0070372 117 116 3.000 0.14355007 0.54419401 0.73308862 1.000 0.946 ! nucleoside monophosphate biosynthetic process GO:0009124 60 60 2.000 0.14706474 0.55658725 1.000 1.000 0.877 ! embryonic pattern specification GO:0009880 60 60 2.000 0.14706474 0.55565961 0.49445285 1.000 0.859 ! regulation of lipid transport GO:0032368 60 60 2.000 0.14706474 0.55473505 1.000 1.000 0.889 ! regulation of tube size GO:0035150 60 60 2.000 0.14706474 0.55381356 1.000 1.000 0.881 ! response to cAMP GO:0051591 60 60 2.000 0.14706474 0.55289513 0.14706474 1.000 0.871 ! cAMP-mediated signaling GO:0019933 118 118 3.000 0.14882524 0.55858745 0.3853991 1.000 0.946 ! stress-activated MAPK cascade GO:0051403 118 118 3.000 0.14882524 0.55766416 0.73911812 1.000 0.946 ! regulation of actin cytoskeleton organization GO:0032956 183 182 4.000 0.15083477 0.56426144 0.87459706 1.000 0.946 ! B cell differentiation GO:0030183 61 61 2.000 0.15097892 0.56387019 1.000 1.000 0.851 ! biomineral tissue development GO:0031214 61 61 2.000 0.15097892 0.56294277 0.50017741 1.000 0.743 ! mesoderm morphogenesis GO:0048332 61 61 2.000 0.15097892 0.5620184 0.50017741 1.000 0.877 ! positive regulation of peptidase activity GO:0010952 119 119 3.000 0.15148621 0.56298237 0.38939761 1.000 0.946 ! stress-activated protein kinase signaling cascade GO:0031098 120 120 3.000 0.15416238 0.57199038 0.74501209 1.000 0.946 ! embryonic heart tube development GO:0035050 62 62 2.000 0.15491371 0.57383887 1.000 1.000 0.883 ! receptor metabolic process GO:0043112 62 62 2.000 0.15491371 0.57290275 1.000 1.000 0.864 ! regulation of fibroblast proliferation GO:0048145 62 62 2.000 0.15491371 0.57196969 1.000 1.000 0.873 ! muscle fiber development GO:0048747 62 62 2.000 0.15491371 0.57103966 0.50583748 1.000 0.849 ! response to interleukin-1 GO:0070555 62 62 2.000 0.15491371 0.57011264 0.50583748 1.000 0.883 ! ion transmembrane transport GO:0034220 186 185 4.000 0.15717711 0.57750489 0.62029699 1.000 0.946 ! antigen processing and presentation of peptide antigen GO:0048002 185 185 4.000 0.15717711 0.57657041 0.15717711 1.000 0.946 ! positive regulation of lymphocyte differentiation GO:0045621 63 63 2.000 0.15886817 0.58183222 1.000 1.000 0.885 ! positive regulation of myeloid cell differentiation GO:0045639 63 63 2.000 0.15886817 0.58089378 0.51143375 1.000 0.882 ! protein heterooligomerization GO:0051291 63 63 2.000 0.15886817 0.57995837 0.51143375 1.000 0.842 ! cardiac muscle cell differentiation GO:0055007 63 63 2.000 0.15886817 0.57902596 1.000 1.000 0.885 ! vitamin metabolic process GO:0006766 122 122 3.000 0.15955911 0.58061077 0.40132331 1.000 0.946 ! cell-cell junction organization GO:0045216 122 122 3.000 0.15955911 0.5796803 0.40132331 1.000 0.946 ! hexose transport GO:0008645 64 64 2.000 0.16284135 0.59065816 0.51696697 1.000 0.761 GO:0015758|glucose transport, ! glucose transport GO:0015758 64 64 2.000 0.16284135 0.59065816 0.51696697 1.000 0.761 GO:0008645|hexose transport, ! negative regulation of MAP kinase activity GO:0043407 64 64 2.000 0.16284135 0.58971462 0.16284135 1.000 0.839 ! central nervous system neuron differentiation GO:0021953 125 124 3.000 0.16501305 0.59662613 0.40921317 1.000 0.946 ! regulation of endocytosis GO:0030100 124 124 3.000 0.16501305 0.59567609 1.000 1.000 0.946 ! positive regulation of cell adhesion GO:0045785 125 124 3.000 0.16501305 0.59472907 0.75640543 1.000 0.946 ! neural crest cell differentiation GO:0014033 65 65 2.000 0.16683234 0.60033161 1.000 1.000 0.885 ! monosaccharide transport GO:0015749 65 65 2.000 0.16683234 0.59938022 0.52243782 1.000 0.764 ! interferon-gamma-mediated signaling pathway GO:0060333 65 65 2.000 0.16683234 0.59843183 0.16683234 1.000 0.830 ! type I interferon-mediated signaling pathway GO:0060337 65 65 2.000 0.16683234 0.59748644 0.16683234 1.000 0.690 GO:0071357|cellular response to type I interferon, ! cellular response to type I interferon GO:0071357 65 65 2.000 0.16683234 0.59748644 0.16683234 1.000 0.690 GO:0060337|type I interferon-mediated signaling pathway, ! regulation of hormone secretion GO:0046883 191 191 4.000 0.17015198 0.6084141 0.88689621 1.000 0.946 ! developmental growth GO:0048589 191 191 4.000 0.17015198 0.60745597 0.63763761 1.000 0.946 ! vasculogenesis GO:0001570 66 66 2.000 0.17084023 0.60895409 1.000 1.000 0.875 ! aminoglycan catabolic process GO:0006026 66 66 2.000 0.17084023 0.60799812 0.17084023 1.000 0.789 ! water-soluble vitamin metabolic process GO:0006767 66 66 2.000 0.17084023 0.60704514 0.52784701 1.000 0.829 ! cell-cell junction assembly GO:0007043 66 66 2.000 0.17084023 0.60609515 0.52784701 1.000 0.769 ! integrin-mediated signaling pathway GO:0007229 66 66 2.000 0.17084023 0.60514813 0.17084023 1.000 0.681 ! response to type I interferon GO:0034340 66 66 2.000 0.17084023 0.60420406 0.17084023 1.000 0.693 ! cellular polysaccharide metabolic process GO:0044264 66 66 2.000 0.17084023 0.60326293 0.52784701 1.000 0.825 ! regulation of biomineral tissue development GO:0070167 66 66 2.000 0.17084023 0.60232473 1.000 1.000 0.869 ! cellular response to tumor necrosis factor GO:0071356 67 66 2.000 0.17084023 0.60138944 0.52784701 1.000 0.865 ! morphogenesis of embryonic epithelium GO:0016331 127 127 3.000 0.17329604 0.60908856 1.000 1.000 0.946 ! protein localization to nucleus GO:0034504 127 127 3.000 0.17329604 0.6081457 0.76461669 1.000 0.946 ! endocrine system development GO:0035270 127 127 3.000 0.17329604 0.60720575 1.000 1.000 0.946 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 67 67 2.000 0.17486414 0.61175463 0.53319524 1.000 0.810 ! ovum-producing ovary development GO:0061039 67 67 2.000 0.17486414 0.61081202 1.000 1.000 0.868 ! activation of MAPK activity GO:0000187 128 128 3.000 0.17608308 0.61412361 0.42483933 1.000 0.946 ! regulation of canonical Wnt receptor signaling pathway GO:0060828 132 129 3.000 0.17888266 0.62292931 0.76993726 1.000 0.946 ! regulation of muscle system process GO:0090257 129 129 3.000 0.17888266 0.6219739 1.000 1.000 0.946 ! cellular response to nutrient GO:0031670 68 68 2.000 0.1789032 0.62109274 1.000 1.000 0.883 ! regulation of transporter activity GO:0032409 68 68 2.000 0.1789032 0.62014305 1.000 1.000 0.878 ! bone morphogenesis GO:0060349 68 68 2.000 0.1789032 0.61919627 0.53848318 1.000 0.867 ! regulation of cAMP biosynthetic process GO:0030817 130 130 3.000 0.18169447 0.62789843 1.000 1.000 0.946 ! regulation of protein import into nucleus GO:0042306 130 130 3.000 0.18169447 0.62694273 0.77255249 1.000 0.946 ! oligosaccharide metabolic process GO:0009311 69 69 2.000 0.18295657 0.6303382 0.54371151 1.000 0.787 ! gliogenesis GO:0042063 133 131 3.000 0.18451824 0.63475396 0.43641812 1.000 0.946 ! signal transduction in response to DNA damage GO:0042770 132 131 3.000 0.18451824 0.63379221 0.43641812 1.000 0.946 ! circadian rhythm GO:0007623 70 70 2.000 0.18702341 0.64142521 0.18702341 1.000 0.836 ! positive regulation of inflammatory response GO:0050729 70 70 2.000 0.18702341 0.64045629 0.54888091 1.000 0.889 ! protein activation cascade GO:0072376 70 70 2.000 0.18702341 0.63949029 0.18702341 1.000 0.667 ! response to unfolded protein GO:0006986 132 132 3.000 0.18735368 0.6396548 0.18735368 1.000 0.746 ! regulation of cAMP metabolic process GO:0030814 132 132 3.000 0.18735368 0.63869291 1.000 1.000 0.946 ! response to mechanical stimulus GO:0009612 133 133 3.000 0.19020049 0.64742418 0.44406743 1.000 0.946 ! appendage morphogenesis GO:0035107 133 133 3.000 0.19020049 0.64645352 1.000 1.000 0.946 GO:0035108|limb morphogenesis, ! limb morphogenesis GO:0035108 133 133 3.000 0.19020049 0.64645352 1.000 1.000 0.946 GO:0035107|appendage morphogenesis, ! myeloid leukocyte differentiation GO:0002573 71 71 2.000 0.1911029 0.64854833 1.000 1.000 0.873 ! glial cell development GO:0021782 73 71 2.000 0.1911029 0.6475789 0.55399202 1.000 0.878 ! osteoblast differentiation GO:0001649 72 72 2.000 0.19519426 0.66045581 0.55904551 1.000 0.872 ! hexose catabolic process GO:0019320 73 73 2.000 0.1992967 0.67333176 0.56404202 1.000 0.855 ! spinal cord development GO:0021510 74 73 2.000 0.1992967 0.67232977 1.000 1.000 0.853 ! neural tube development GO:0021915 137 137 3.000 0.20169575 0.67941199 1.000 1.000 0.946 ! GTP metabolic process GO:0046039 137 137 3.000 0.20169575 0.67840397 0.45919222 1.000 0.772 ! protein demethylation GO:0006482 20 20 1.000 0.20317125 0.68235439 1.000 1.000 0.630 GO:0008214|protein dealkylation, ! C21-steroid hormone biosynthetic process GO:0006700 20 20 1.000 0.20317125 0.68134499 1.000 1.000 0.691 ! Notch receptor processing GO:0007220 20 20 1.000 0.20317125 0.68033858 0.20317125 1.000 0.664 ! protein dealkylation GO:0008214 20 20 1.000 0.20317125 0.68235439 1.000 1.000 0.630 GO:0006482|protein demethylation, ! induction of apoptosis by extracellular signals GO:0008624 20 20 1.000 0.20317125 0.67933513 0.20317125 1.000 0.626 ! response to pH GO:0009268 20 20 1.000 0.20317125 0.67833463 1.000 1.000 0.696 ! regulation of peptidyl-threonine phosphorylation GO:0010799 20 20 1.000 0.20317125 0.67733708 0.20317125 1.000 0.764 ! regulation of myotube differentiation GO:0010830 20 20 1.000 0.20317125 0.67634246 1.000 1.000 0.707 ! pentose metabolic process GO:0019321 20 20 1.000 0.20317125 0.67535076 0.20317125 1.000 0.699 ! positive regulation of interleukin-8 production GO:0032757 20 20 1.000 0.20317125 0.67436196 1.000 1.000 0.795 ! response to testosterone stimulus GO:0033574 20 20 1.000 0.20317125 0.67337605 1.000 1.000 0.738 ! vasoconstriction GO:0042310 20 20 1.000 0.20317125 0.67239302 1.000 1.000 0.783 ! sarcomere organization GO:0045214 20 20 1.000 0.20317125 0.67141285 1.000 1.000 0.674 ! regulation of myoblast differentiation GO:0045661 21 20 1.000 0.20317125 0.67043554 1.000 1.000 0.745 ! positive regulation of smooth muscle contraction GO:0045987 20 20 1.000 0.20317125 0.66946107 1.000 1.000 0.787 ! embryonic digestive tract morphogenesis GO:0048557 20 20 1.000 0.20317125 0.66848943 1.000 1.000 0.849 ! positive regulation of coagulation GO:0050820 20 20 1.000 0.20317125 0.6675206 1.000 1.000 0.786 ! cytoplasmic sequestering of protein GO:0051220 20 20 1.000 0.20317125 0.66655458 0.20317125 1.000 0.704 ! ventricular cardiac muscle cell differentiation GO:0055012 20 20 1.000 0.20317125 0.66559135 1.000 1.000 0.805 ! maternal process involved in female pregnancy GO:0060135 20 20 1.000 0.20317125 0.6646309 1.000 1.000 0.733 ! regulation of neutrophil chemotaxis GO:0090022 20 20 1.000 0.20317125 0.66367322 1.000 1.000 0.808 ! hair follicle development GO:0001942 74 74 2.000 0.20340944 0.66349526 0.56898219 1.000 0.870 GO:0022405|hair cycle process, GO:0022404|molting cycle process, ! molting cycle process GO:0022404 74 74 2.000 0.20340944 0.66349526 0.56898219 1.000 0.870 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! hair cycle process GO:0022405 74 74 2.000 0.20340944 0.66349526 0.56898219 1.000 0.870 GO:0022404|molting cycle process, GO:0001942|hair follicle development, ! mesenchyme development GO:0060485 138 138 3.000 0.20459516 0.66640407 0.79243686 1.000 0.946 ! cell cycle arrest GO:0007050 139 139 3.000 0.20750424 0.67490979 0.79479753 1.000 0.946 ! response to topologically incorrect protein GO:0035966 139 139 3.000 0.20750424 0.67394287 0.20750424 1.000 0.776 ! antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479 75 75 2.000 0.20753175 0.67306792 0.20753175 1.000 0.836 ! cellular response to starvation GO:0009267 76 75 2.000 0.20753175 0.67210639 0.57386666 1.000 0.843 ! positive regulation of transmembrane transport GO:0034764 75 75 2.000 0.20753175 0.67114761 0.57386666 1.000 0.888 ! negative regulation of MAPK cascade GO:0043409 76 76 2.000 0.21166288 0.68353241 0.21166288 1.000 0.860 ! regulation of receptor internalization GO:0002090 21 21 1.000 0.21217395 0.68420818 1.000 1.000 0.766 ! regulation of membrane depolarization GO:0003254 21 21 1.000 0.21217395 0.6832363 1.000 1.000 0.780 ! detection of visible light GO:0009584 21 21 1.000 0.21217395 0.68226717 0.21217395 1.000 0.634 ! dorsal/ventral axis specification GO:0009950 21 21 1.000 0.21217395 0.68130078 1.000 1.000 0.758 ! lipid storage GO:0019915 21 21 1.000 0.21217395 0.68033713 1.000 1.000 0.752 ! central nervous system projection neuron axonogenesis GO:0021952 21 21 1.000 0.21217395 0.67937621 0.21217395 1.000 0.743 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 21 21 1.000 0.21217395 0.67841799 0.21217395 1.000 0.763 ! collagen catabolic process GO:0030574 21 21 1.000 0.21217395 0.67746247 0.21217395 1.000 0.0766 ! regulation of Cdc42 protein signal transduction GO:0032489 21 21 1.000 0.21217395 0.67650964 1.000 1.000 0.615 ! plasma lipoprotein particle clearance GO:0034381 21 21 1.000 0.21217395 0.67555949 1.000 1.000 0.829 ! negative regulation of insulin receptor signaling pathway GO:0046627 21 21 1.000 0.21217395 0.674612 1.000 1.000 0.787 ! circadian behavior GO:0048512 21 21 1.000 0.21217395 0.67366716 0.21217395 1.000 0.818 ! erythrocyte development GO:0048821 21 21 1.000 0.21217395 0.67272497 1.000 1.000 0.728 ! regulation of interleukin-1 secretion GO:0050704 21 21 1.000 0.21217395 0.67178541 1.000 1.000 0.803 ! mitochondrion localization GO:0051646 21 21 1.000 0.21217395 0.67084847 1.000 1.000 0.624 ! negative regulation of ERK1 and ERK2 cascade GO:0070373 21 21 1.000 0.21217395 0.66991414 0.21217395 1.000 0.737 ! cellular response to glucocorticoid stimulus GO:0071385 21 21 1.000 0.21217395 0.66898241 0.21217395 1.000 0.771 ! metanephric nephron morphogenesis GO:0072273 21 21 1.000 0.21217395 0.66805327 1.000 1.000 0.860 ! regulation of lymphocyte migration GO:2000401 22 21 1.000 0.21217395 0.6671267 1.000 1.000 0.794 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 143 3.000 0.21923178 0.6883635 0.21923178 1.000 0.946 ! defense response to virus GO:0051607 147 143 3.000 0.21923178 0.68741141 0.48142692 1.000 0.946 ! spermatid development GO:0007286 78 78 2.000 0.21994876 0.68870697 0.58819203 1.000 0.734 ! regulation of the force of heart contraction GO:0002026 22 22 1.000 0.22107545 0.69128005 1.000 1.000 0.813 ! regulation of gluconeogenesis GO:0006111 22 22 1.000 0.22107545 0.69032787 1.000 1.000 0.708 ! protein ADP-ribosylation GO:0006471 22 22 1.000 0.22107545 0.68937831 0.22107545 1.000 0.454 ! membrane protein ectodomain proteolysis GO:0006509 22 22 1.000 0.22107545 0.68843137 0.22107545 1.000 0.636 ! hormone-mediated signaling pathway GO:0009755 22 22 1.000 0.22107545 0.68748702 1.000 1.000 0.689 ! phosphatidylinositol 3-kinase cascade GO:0014065 22 22 1.000 0.22107545 0.68654525 1.000 1.000 0.692 ! peptide hormone processing GO:0016486 22 22 1.000 0.22107545 0.68560607 0.22107545 1.000 0.459 ! cholesterol efflux GO:0033344 22 22 1.000 0.22107545 0.68466945 1.000 1.000 0.774 ! response to gonadotropin stimulus GO:0034698 23 22 1.000 0.22107545 0.68373538 1.000 1.000 0.806 ! dopamine metabolic process GO:0042417 22 22 1.000 0.22107545 0.68280386 1.000 1.000 0.820 ! pteridine-containing compound biosynthetic process GO:0042559 22 22 1.000 0.22107545 0.68187488 1.000 1.000 0.745 ! blood vessel endothelial cell migration GO:0043534 22 22 1.000 0.22107545 0.68094842 1.000 1.000 0.790 ! regulation of T-helper cell differentiation GO:0045622 22 22 1.000 0.22107545 0.68002447 1.000 1.000 0.839 ! vitamin transport GO:0051180 22 22 1.000 0.22107545 0.67910303 0.22107545 1.000 0.612 ! heart trabecula morphogenesis GO:0061384 22 22 1.000 0.22107545 0.67818408 0.22107545 1.000 0.817 ! response to fatty acid GO:0070542 22 22 1.000 0.22107545 0.67726761 1.000 1.000 0.779 ! cellular response to corticosteroid stimulus GO:0071384 22 22 1.000 0.22107545 0.67635362 0.22107545 1.000 0.784 ! cell communication involved in cardiac conduction GO:0086065 22 22 1.000 0.22107545 0.67544209 1.000 1.000 0.805 ! regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 22 1.000 0.22107545 0.67453302 1.000 1.000 0.815 ! positive regulation of release of cytochrome c from mitochondria GO:0090200 22 22 1.000 0.22107545 0.67362639 1.000 1.000 0.710 ! epithelial cell development GO:0002064 79 79 2.000 0.22410211 0.68193221 0.22410211 1.000 0.886 ! antigen processing and presentation of exogenous peptide antigen via MHC class I GO:0042590 79 79 2.000 0.22410211 0.68101809 0.22410211 1.000 0.840 ! regulation of cytokine secretion GO:0050707 80 79 2.000 0.22410211 0.68010642 0.59285985 1.000 0.884 ! cellular response to nutrient levels GO:0031669 147 146 3.000 0.22811554 0.69136086 0.81059072 1.000 0.946 ! negative regulation of epithelial cell proliferation GO:0050680 80 80 2.000 0.2282615 0.69087961 0.59747502 1.000 0.879 ! protein tetramerization GO:0051262 80 80 2.000 0.2282615 0.68995844 0.59747502 1.000 0.870 ! negative regulation of canonical Wnt receptor signaling pathway GO:0090090 83 80 2.000 0.2282615 0.68903972 0.59747502 1.000 0.868 ! protein import into nucleus, translocation GO:0000060 23 23 1.000 0.22987685 0.69299312 1.000 1.000 0.701 ! regulation of type 2 immune response GO:0002828 24 23 1.000 0.22987685 0.69207281 1.000 1.000 0.834 ! rhythmic behavior GO:0007622 23 23 1.000 0.22987685 0.69115494 0.22987685 1.000 0.829 ! motor axon guidance GO:0008045 23 23 1.000 0.22987685 0.6902395 0.22987685 1.000 0.693 ! phospholipid catabolic process GO:0009395 23 23 1.000 0.22987685 0.68932649 1.000 1.000 0.621 ! regulation of platelet activation GO:0010543 23 23 1.000 0.22987685 0.68841588 1.000 1.000 0.807 ! regulation of hormone metabolic process GO:0032350 23 23 1.000 0.22987685 0.68750768 1.000 1.000 0.825 ! positive regulation of ion transmembrane transporter activity GO:0032414 23 23 1.000 0.22987685 0.68660188 1.000 1.000 0.790 ! NIK/NF-kappaB cascade GO:0038061 23 23 1.000 0.22987685 0.68569845 0.22987685 1.000 0.637 ! neurotransmitter metabolic process GO:0042133 23 23 1.000 0.22987685 0.6847974 0.22987685 1.000 0.731 ! middle ear morphogenesis GO:0042474 23 23 1.000 0.22987685 0.68389872 1.000 1.000 0.671 ! negative regulation of T cell differentiation GO:0045581 24 23 1.000 0.22987685 0.68300239 1.000 1.000 0.809 ! negative regulation of glial cell differentiation GO:0045686 23 23 1.000 0.22987685 0.68210841 1.000 1.000 0.800 ! positive regulation of vasodilation GO:0045909 23 23 1.000 0.22987685 0.68121676 1.000 1.000 0.835 ! regulation of astrocyte differentiation GO:0048710 23 23 1.000 0.22987685 0.68032745 1.000 1.000 0.817 ! chemokine-mediated signaling pathway GO:0070098 23 23 1.000 0.22987685 0.67944045 0.22987685 1.000 0.481 ! triglyceride homeostasis GO:0070328 23 23 1.000 0.22987685 0.67855576 0.22987685 1.000 0.769 ! regulation of cardiac muscle cell contraction GO:0086004 23 23 1.000 0.22987685 0.67767337 1.000 1.000 0.807 ! regulation of triglyceride metabolic process GO:0090207 23 23 1.000 0.22987685 0.67679328 1.000 1.000 0.780 ! negative regulation of cellular response to insulin stimulus GO:1900077 23 23 1.000 0.22987685 0.67591547 1.000 1.000 0.804 ! lung development GO:0030324 147 147 3.000 0.23109213 0.67860864 0.81274588 1.000 0.946 ! metanephros development GO:0001656 81 81 2.000 0.23242627 0.6816434 1.000 1.000 0.891 ! protein localization in membrane GO:0072657 82 81 2.000 0.23242627 0.68076272 0.60203813 1.000 0.873 ! cellular respiration GO:0045333 149 148 3.000 0.23407596 0.68470993 0.23407596 1.000 0.946 ! cellular response to abiotic stimulus GO:0071214 150 148 3.000 0.23407596 0.68382757 0.4995235 1.000 0.946 ! glucosamine metabolic process GO:0006041 24 24 1.000 0.2385793 0.69608657 0.2385793 1.000 0.675 GO:0006044|N-acetylglucosamine metabolic process, ! N-acetylglucosamine metabolic process GO:0006044 24 24 1.000 0.2385793 0.69608657 0.2385793 1.000 0.675 GO:0006041|glucosamine metabolic process, ! glutamate metabolic process GO:0006536 24 24 1.000 0.2385793 0.69519186 0.2385793 1.000 0.802 ! folic acid-containing compound metabolic process GO:0006760 24 24 1.000 0.2385793 0.69429944 1.000 1.000 0.735 ! sex determination GO:0007530 24 24 1.000 0.2385793 0.69340931 1.000 1.000 0.713 ! glutamine family amino acid catabolic process GO:0009065 24 24 1.000 0.2385793 0.69252146 0.2385793 1.000 0.814 ! regulation of glycoprotein biosynthetic process GO:0010559 25 24 1.000 0.2385793 0.69163589 0.2385793 1.000 0.797 ! regulation of muscle cell apoptosis GO:0010660 24 24 1.000 0.2385793 0.69075257 1.000 1.000 0.841 ! adrenal gland development GO:0030325 24 24 1.000 0.2385793 0.68987151 1.000 1.000 0.811 ! regulation of histone methylation GO:0031060 24 24 1.000 0.2385793 0.68899269 1.000 1.000 0.757 ! regulation of interleukin-10 production GO:0032653 24 24 1.000 0.2385793 0.68811611 0.2385793 1.000 0.831 ! embryonic hemopoiesis GO:0035162 24 24 1.000 0.2385793 0.68724176 1.000 1.000 0.705 ! regulation of epidermal cell differentiation GO:0045604 24 24 1.000 0.2385793 0.68636962 0.2385793 1.000 0.712 ! filopodium assembly GO:0046847 24 24 1.000 0.2385793 0.6854997 1.000 1.000 0.308 ! regulation of defense response to virus by host GO:0050691 25 24 1.000 0.2385793 0.68463198 1.000 1.000 0.804 ! regulation of interferon-gamma-mediated signaling pathway GO:0060334 24 24 1.000 0.2385793 0.68376645 1.000 1.000 0.749 ! chaperone-mediated protein folding GO:0061077 24 24 1.000 0.2385793 0.68290311 0.2385793 1.000 0.402 ! regulation of intrinsic apoptotic signaling pathway GO:2001242 24 24 1.000 0.2385793 0.68204195 0.2385793 1.000 0.776 ! respiratory tube development GO:0030323 150 150 3.000 0.24006424 0.68542272 0.81906607 1.000 0.946 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 83 83 2.000 0.24076934 0.68657119 1.000 1.000 0.892 ! female gonad development GO:0008585 83 83 2.000 0.24076934 0.68570867 1.000 1.000 0.876 ! regulation of glucose transport GO:0010827 85 83 2.000 0.24076934 0.6848483 1.000 1.000 0.946 ! spermatid differentiation GO:0048515 83 83 2.000 0.24076934 0.6839901 0.6110105 1.000 0.749 ! endoplasmic reticulum unfolded protein response GO:0030968 84 84 2.000 0.2449464 0.69498559 0.2449464 1.000 0.773 ! response to tumor necrosis factor GO:0034612 85 84 2.000 0.2449464 0.69411686 0.61542091 1.000 0.875 ! response to hydrogen peroxide GO:0042542 84 84 2.000 0.2449464 0.6932503 0.61542091 1.000 0.884 ! cellular response to interferon-gamma GO:0071346 84 84 2.000 0.2449464 0.6923859 0.2449464 1.000 0.946 ! positive regulation of cell-matrix adhesion GO:0001954 25 25 1.000 0.24718388 0.69784042 1.000 1.000 0.815 ! DNA fragmentation involved in apoptotic nuclear change GO:0006309 25 25 1.000 0.24718388 0.69697246 1.000 1.000 0.659 ! spinal cord motor neuron differentiation GO:0021522 25 25 1.000 0.24718388 0.69610666 1.000 1.000 0.703 ! tumor necrosis factor-mediated signaling pathway GO:0033209 26 25 1.000 0.24718388 0.695243 0.24718388 1.000 0.588 ! regulation of odontogenesis GO:0042481 25 25 1.000 0.24718388 0.69438149 1.000 1.000 0.775 ! regulation of ATPase activity GO:0043462 25 25 1.000 0.24718388 0.69352211 1.000 1.000 0.696 ! positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 25 25 1.000 0.24718388 0.69266485 1.000 1.000 0.834 ! regulation of bone resorption GO:0045124 25 25 1.000 0.24718388 0.6918097 1.000 1.000 0.821 ! positive regulation of muscle contraction GO:0045933 25 25 1.000 0.24718388 0.69095667 1.000 1.000 0.827 ! regulation of activated T cell proliferation GO:0046006 25 25 1.000 0.24718388 0.69010574 0.24718388 1.000 0.826 ! regulation of response to interferon-gamma GO:0060330 25 25 1.000 0.24718388 0.6892569 1.000 1.000 0.734 ! intrinsic apoptotic signaling pathway GO:0097193 25 25 1.000 0.24718388 0.68841015 1.000 1.000 0.722 ! neural tube formation GO:0001841 85 85 2.000 0.24912633 0.69296857 1.000 1.000 0.870 ! female gamete generation GO:0007292 86 85 2.000 0.24912633 0.69211934 0.61978156 1.000 0.946 ! positive regulation of cAMP metabolic process GO:0030816 85 85 2.000 0.24912633 0.69127219 1.000 1.000 0.877 GO:0030819|positive regulation of cAMP biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 85 85 2.000 0.24912633 0.69127219 1.000 1.000 0.877 GO:0030816|positive regulation of cAMP metabolic process, ! cellular response to unfolded protein GO:0034620 85 85 2.000 0.24912633 0.69042712 0.24912633 1.000 0.777 ! canonical Wnt receptor signaling pathway GO:0060070 85 85 2.000 0.24912633 0.6895841 0.61978156 1.000 0.884 ! amine biosynthetic process GO:0009309 154 154 3.000 0.2521161 0.69700878 0.52070118 1.000 0.946 ! DNA catabolic process, endonucleolytic GO:0000737 26 26 1.000 0.25569171 0.70603301 1.000 1.000 0.679 ! B cell activation involved in immune response GO:0002312 26 26 1.000 0.25569171 0.70517409 1.000 1.000 0.821 ! metanephros morphogenesis GO:0003338 26 26 1.000 0.25569171 0.70431725 1.000 1.000 0.873 ! nucleotide-sugar metabolic process GO:0009225 26 26 1.000 0.25569171 0.7034625 0.25569171 1.000 0.730 ! regulation of cell fate commitment GO:0010453 26 26 1.000 0.25569171 0.70260982 0.25569171 1.000 0.861 ! response to progesterone stimulus GO:0032570 26 26 1.000 0.25569171 0.7017592 0.25569171 1.000 0.805 ! negative regulation of homeostatic process GO:0032845 26 26 1.000 0.25569171 0.70091064 1.000 1.000 0.836 ! auditory receptor cell differentiation GO:0042491 26 26 1.000 0.25569171 0.70006413 1.000 1.000 0.751 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 27 26 1.000 0.25569171 0.69921966 0.25569171 1.000 0.718 ! sympathetic nervous system development GO:0048485 26 26 1.000 0.25569171 0.69837723 1.000 1.000 0.822 ! cytokine secretion GO:0050663 26 26 1.000 0.25569171 0.69753682 1.000 1.000 0.779 ! positive regulation of lipid kinase activity GO:0090218 26 26 1.000 0.25569171 0.69669844 1.000 1.000 0.833 ! negative regulation of catabolic process GO:0009895 87 87 2.000 0.25749242 0.70076268 0.25749242 1.000 0.880 ! response to calcium ion GO:0051592 87 87 2.000 0.25749242 0.69992244 0.6283558 1.000 0.946 ! regulation of lipase activity GO:0060191 156 156 3.000 0.25817561 0.70093904 0.52762703 1.000 0.946 ! regulation of interphase of mitotic cell cycle GO:2000602 157 157 3.000 0.26121288 0.70833683 1.000 1.000 0.946 ! cytokinesis GO:0000910 88 88 2.000 0.26167744 0.7087488 0.26167744 1.000 0.794 ! axis specification GO:0009798 88 88 2.000 0.26167744 0.70790304 0.6325705 1.000 0.888 ! positive regulation of ERK1 and ERK2 cascade GO:0070374 89 88 2.000 0.26167744 0.70705929 1.000 1.000 0.888 ! multicellular organismal aging GO:0010259 27 27 1.000 0.26410385 0.71276599 1.000 1.000 0.803 ! keratan sulfate biosynthetic process GO:0018146 27 27 1.000 0.26410385 0.71191847 0.26410385 1.000 0.336 ! central nervous system neuron axonogenesis GO:0021955 27 27 1.000 0.26410385 0.71107296 0.26410385 1.000 0.801 ! eye photoreceptor cell development GO:0042462 27 27 1.000 0.26410385 0.71022946 1.000 1.000 0.710 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 27 27 1.000 0.26410385 0.70938795 1.000 1.000 0.830 ! neuron maturation GO:0042551 27 27 1.000 0.26410385 0.70854844 0.26410385 1.000 0.657 ! regulation of phosphatidylinositol 3-kinase activity GO:0043551 27 27 1.000 0.26410385 0.70771091 1.000 1.000 0.836 ! positive regulation of fatty acid metabolic process GO:0045923 27 27 1.000 0.26410385 0.70687536 1.000 1.000 0.845 ! vesicle targeting, to, from or within Golgi GO:0048199 27 27 1.000 0.26410385 0.70604178 0.26410385 1.000 0.636 ! B cell receptor signaling pathway GO:0050853 27 27 1.000 0.26410385 0.70521017 1.000 1.000 0.694 ! positive regulation of stress fiber assembly GO:0051496 27 27 1.000 0.26410385 0.70438051 1.000 1.000 0.759 ! growth hormone receptor signaling pathway GO:0060396 27 27 1.000 0.26410385 0.7035528 0.26410385 1.000 0.767 ! nucleotide-binding oligomerization domain containing signaling pathway GO:0070423 27 27 1.000 0.26410385 0.70272703 1.000 1.000 0.774 ! regulation of cardiac muscle cell action potential GO:0086001 27 27 1.000 0.26410385 0.7019032 1.000 1.000 0.812 ! protein targeting to membrane GO:0006612 159 158 3.000 0.26425483 0.70148208 0.53448527 1.000 0.946 ! cyclic-nucleotide-mediated signaling GO:0019935 158 158 3.000 0.26425483 0.70066164 0.53448527 1.000 0.946 ! regulation of protein catabolic process GO:0042176 159 159 3.000 0.26730122 0.70791107 0.53788889 1.000 0.946 ! post-embryonic development GO:0009791 91 90 2.000 0.27004864 0.7143527 0.64085773 1.000 0.946 ! cellular response to topologically incorrect protein GO:0035967 90 90 2.000 0.27004864 0.71352012 0.27004864 1.000 0.794 ! protein deacetylation GO:0006476 28 28 1.000 0.27242139 0.71895144 0.27242139 1.000 0.727 ! purine ribonucleoside monophosphate metabolic process GO:0009167 28 28 1.000 0.27242139 0.71811545 1.000 1.000 0.800 ! detection of biotic stimulus GO:0009595 28 28 1.000 0.27242139 0.7172814 0.27242139 1.000 0.834 ! positive regulation of mitochondrion organization GO:0010822 29 28 1.000 0.27242139 0.71644929 1.000 1.000 0.768 ! regulation of toll-like receptor signaling pathway GO:0034121 28 28 1.000 0.27242139 0.71561911 1.000 1.000 0.826 ! regulation of CD4-positive, alpha-beta T cell differentiation GO:0043370 28 28 1.000 0.27242139 0.71479084 1.000 1.000 0.857 ! regulation of muscle adaptation GO:0043502 28 28 1.000 0.27242139 0.7139645 1.000 1.000 0.845 ! regulation of phosphoprotein phosphatase activity GO:0043666 28 28 1.000 0.27242139 0.71314006 0.27242139 1.000 0.671 ! multicellular organismal catabolic process GO:0044243 28 28 1.000 0.27242139 0.71231752 0.27242139 1.000 0.434 ! cAMP metabolic process GO:0046058 28 28 1.000 0.27242139 0.71149688 1.000 1.000 0.758 ! positive regulation of glucose import GO:0046326 29 28 1.000 0.27242139 0.71067812 1.000 1.000 0.782 ! regulation of bone remodeling GO:0046850 28 28 1.000 0.27242139 0.70986125 1.000 1.000 0.829 ! regulation of lipoprotein lipase activity GO:0051004 28 28 1.000 0.27242139 0.70904626 0.27242139 1.000 0.832 ! neuron apoptosis GO:0051402 28 28 1.000 0.27242139 0.70823313 1.000 1.000 0.724 ! placenta blood vessel development GO:0060674 28 28 1.000 0.27242139 0.70742187 1.000 1.000 0.747 ! cellular response to growth hormone stimulus GO:0071378 28 28 1.000 0.27242139 0.70661246 0.27242139 1.000 0.779 ! nephron epithelium morphogenesis GO:0072088 28 28 1.000 0.27242139 0.7058049 1.000 1.000 0.865 ! cytokine production GO:0001816 91 91 2.000 0.27423375 0.70968939 1.000 1.000 0.884 ! regulation of adaptive immune response GO:0002819 91 91 2.000 0.27423375 0.70888017 1.000 1.000 0.892 ! regulation of cytokine biosynthetic process GO:0042035 91 91 2.000 0.27423375 0.70807279 0.64493133 1.000 0.887 ! response to organic cyclic compound GO:0014070 162 162 3.000 0.27646465 0.71302088 0.84229362 1.000 0.946 ! protein import GO:0017038 163 162 3.000 0.27646465 0.71221063 0.84229362 1.000 0.946 ! anatomical structure homeostasis GO:0060249 162 162 3.000 0.27646465 0.71140222 0.54799711 1.000 0.946 ! cell growth GO:0016049 92 92 2.000 0.27841784 0.71561591 1.000 1.000 0.946 ! protein N-linked glycosylation via asparagine GO:0018279 92 92 2.000 0.27841784 0.71480547 0.27841784 1.000 0.768 ! response to retinoic acid GO:0032526 92 92 2.000 0.27841784 0.71399687 1.000 1.000 0.946 ! response to alkaloid GO:0043279 92 92 2.000 0.27841784 0.71319009 1.000 1.000 0.890 ! tricarboxylic acid cycle GO:0006099 29 29 1.000 0.28064538 0.71808473 0.28064538 1.000 0.772 ! heterophilic cell-cell adhesion GO:0007157 30 29 1.000 0.28064538 0.71727516 0.28064538 1.000 0.464 ! androgen metabolic process GO:0008209 29 29 1.000 0.28064538 0.71646742 1.000 1.000 0.802 ! purine nucleoside monophosphate metabolic process GO:0009126 29 29 1.000 0.28064538 0.71566149 1.000 1.000 0.801 ! peptide cross-linking GO:0018149 29 29 1.000 0.28064538 0.71485738 0.28064538 1.000 0.325 ! natural killer cell activation GO:0030101 29 29 1.000 0.28064538 0.71405507 1.000 1.000 0.653 ! positive regulation of BMP signaling pathway GO:0030513 29 29 1.000 0.28064538 0.71325456 1.000 1.000 0.815 ! positive regulation of lipid transport GO:0032370 29 29 1.000 0.28064538 0.71245584 1.000 1.000 0.857 ! positive regulation of transporter activity GO:0032411 29 29 1.000 0.28064538 0.71165891 1.000 1.000 0.793 ! nucleoside bisphosphate metabolic process GO:0033865 29 29 1.000 0.28064538 0.71086376 1.000 1.000 0.702 ! protein deacylation GO:0035601 29 29 1.000 0.28064538 0.71007039 0.28064538 1.000 0.739 ! positive regulation of DNA binding GO:0043388 29 29 1.000 0.28064538 0.70927878 1.000 1.000 0.855 ! regulation of insulin receptor signaling pathway GO:0046626 29 29 1.000 0.28064538 0.70848894 1.000 1.000 0.817 ! oocyte development GO:0048599 29 29 1.000 0.28064538 0.70770086 1.000 1.000 0.787 ! face morphogenesis GO:0060325 29 29 1.000 0.28064538 0.70691452 0.28064538 1.000 0.797 ! peptidyl-asparagine modification GO:0018196 93 93 2.000 0.28260039 0.71104893 0.28260039 1.000 0.774 ! lipoprotein metabolic process GO:0042157 93 93 2.000 0.28260039 0.71026063 0.65294111 1.000 0.946 ! positive regulation of lipid metabolic process GO:0045834 93 93 2.000 0.28260039 0.70947407 1.000 1.000 0.892 ! negative regulation of protein ubiquitination GO:0031397 94 94 2.000 0.28678092 0.71917295 1.000 1.000 0.946 ! amino sugar metabolic process GO:0006040 30 30 1.000 0.28877686 0.72337806 0.28877686 1.000 0.688 ! negative regulation of gliogenesis GO:0014014 30 30 1.000 0.28877686 0.72257963 1.000 1.000 0.835 ! long-chain fatty acid transport GO:0015909 30 30 1.000 0.28877686 0.72178296 1.000 1.000 0.807 ! extracellular matrix disassembly GO:0022617 30 30 1.000 0.28877686 0.72098805 0.28877686 1.000 0.465 ! homotypic cell-cell adhesion GO:0034109 30 30 1.000 0.28877686 0.72019488 1.000 1.000 0.795 ! negative regulation of transcription factor import into nucleus GO:0042992 30 30 1.000 0.28877686 0.71940346 0.28877686 1.000 0.796 ! acetyl-CoA catabolic process GO:0046356 30 30 1.000 0.28877686 0.71861377 0.28877686 1.000 0.780 ! negative regulation of Ras protein signal transduction GO:0046580 30 30 1.000 0.28877686 0.71782582 1.000 1.000 0.581 ! positive regulation of phagocytosis GO:0050766 30 30 1.000 0.28877686 0.71703959 1.000 1.000 0.820 ! protein trimerization GO:0070206 30 30 1.000 0.28877686 0.71625508 0.28877686 1.000 0.624 ! cellular response to calcium ion GO:0071277 30 30 1.000 0.28877686 0.71547229 1.000 1.000 0.765 ! protein-lipid complex subunit organization GO:0071825 30 30 1.000 0.28877686 0.71469121 1.000 1.000 0.847 GO:0071827|plasma lipoprotein particle organization, ! plasma lipoprotein particle organization GO:0071827 30 30 1.000 0.28877686 0.71469121 1.000 1.000 0.847 GO:0071825|protein-lipid complex subunit organization, ! regulation of cardiac muscle cell membrane potential GO:0086036 30 30 1.000 0.28877686 0.71391183 1.000 1.000 0.816 ! regulation of CD4-positive, alpha-beta T cell activation GO:2000514 30 30 1.000 0.28877686 0.71313414 1.000 1.000 0.863 ! regulation of peptidyl-lysine acetylation GO:2000756 30 30 1.000 0.28877686 0.71235816 1.000 1.000 0.828 ! regulation of cation channel activity GO:2001257 30 30 1.000 0.28877686 0.71158385 1.000 1.000 0.815 ! bone development GO:0060348 95 95 2.000 0.29095893 0.71618231 0.66077107 1.000 0.946 ! antigen processing and presentation of exogenous peptide antigen GO:0002478 168 168 3.000 0.29487945 0.72504525 0.29487945 1.000 0.946 ! regulation of Rho protein signal transduction GO:0035023 170 168 3.000 0.29487945 0.72425972 0.8527692 1.000 0.946 ! respiratory system development GO:0060541 168 168 3.000 0.29487945 0.72347589 0.8527692 1.000 0.946 ! ER-nucleus signaling pathway GO:0006984 96 96 2.000 0.29513397 0.72331751 0.29513397 1.000 0.946 ! negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO:0090101 96 96 2.000 0.29513397 0.72253639 0.66461989 1.000 0.946 ! cytoplasmic pattern recognition receptor signaling pathway GO:0002753 31 31 1.000 0.29681688 0.72587256 1.000 1.000 0.806 ! salivary gland morphogenesis GO:0007435 31 31 1.000 0.29681688 0.72509037 1.000 1.000 0.845 ! oocyte differentiation GO:0009994 31 31 1.000 0.29681688 0.72430987 1.000 1.000 0.795 ! regulation of gastrulation GO:0010470 32 31 1.000 0.29681688 0.72353104 0.29681688 1.000 0.866 ! positive regulation of glucose metabolic process GO:0010907 31 31 1.000 0.29681688 0.72275388 1.000 1.000 0.831 ! negative regulation of neuron projection development GO:0010977 31 31 1.000 0.29681688 0.7219784 0.29681688 1.000 0.757 ! aromatic compound biosynthetic process GO:0019438 31 31 1.000 0.29681688 0.72120457 1.000 1.000 0.810 ! positive regulation of cell-cell adhesion GO:0022409 32 31 1.000 0.29681688 0.7204324 0.29681688 1.000 0.820 ! membrane protein proteolysis GO:0033619 31 31 1.000 0.29681688 0.71966189 0.29681688 1.000 0.738 ! response to nicotine GO:0035094 31 31 1.000 0.29681688 0.71889302 1.000 1.000 0.833 ! negative regulation of small GTPase mediated signal transduction GO:0051058 31 31 1.000 0.29681688 0.71812579 1.000 1.000 0.606 ! regulation of lymphocyte apoptosis GO:0070228 31 31 1.000 0.29681688 0.7173602 1.000 1.000 0.841 ! nephron morphogenesis GO:0072028 31 31 1.000 0.29681688 0.71659624 1.000 1.000 0.874 ! carbohydrate transport GO:0008643 97 97 2.000 0.29930555 0.72183582 0.66842524 1.000 0.757 ! positive regulation of lymphocyte proliferation GO:0050671 97 97 2.000 0.29930555 0.72106873 1.000 1.000 0.891 ! antigen processing and presentation of exogenous antigen GO:0019884 170 170 3.000 0.30103709 0.72447037 0.30103709 1.000 0.946 ! positive regulation of mononuclear cell proliferation GO:0032946 98 98 2.000 0.30347323 0.72955865 1.000 1.000 0.891 ! negative regulation of myeloid leukocyte differentiation GO:0002762 32 32 1.000 0.30476645 0.73189147 1.000 1.000 0.811 ! regulation of immunoglobulin mediated immune response GO:0002889 32 32 1.000 0.30476645 0.73111698 1.000 1.000 0.870 ! dolichol-linked oligosaccharide biosynthetic process GO:0006488 32 32 1.000 0.30476645 0.73034413 0.30476645 1.000 0.620 ! superoxide metabolic process GO:0006801 32 32 1.000 0.30476645 0.72957291 1.000 1.000 0.802 ! lysosome organization GO:0007040 32 32 1.000 0.30476645 0.72880332 1.000 1.000 0.697 ! positive regulation of glucose transport GO:0010828 33 32 1.000 0.30476645 0.72803535 1.000 1.000 0.807 ! apoptotic nuclear change GO:0030262 32 32 1.000 0.30476645 0.727269 1.000 1.000 0.702 ! bone mineralization GO:0030282 32 32 1.000 0.30476645 0.72650426 0.30476645 1.000 0.693 ! midbrain development GO:0030901 32 32 1.000 0.30476645 0.72574112 1.000 1.000 0.714 ! keratan sulfate metabolic process GO:0042339 32 32 1.000 0.30476645 0.72497959 0.30476645 1.000 0.475 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 32 32 1.000 0.30476645 0.72421965 1.000 1.000 0.831 ! regulation of lipid kinase activity GO:0043550 32 32 1.000 0.30476645 0.72346131 1.000 1.000 0.824 ! positive regulation of oxidoreductase activity GO:0051353 32 32 1.000 0.30476645 0.72270455 1.000 1.000 0.864 ! response to growth hormone stimulus GO:0060416 32 32 1.000 0.30476645 0.72194937 0.30476645 1.000 0.796 ! cochlea development GO:0090102 32 32 1.000 0.30476645 0.72119577 1.000 1.000 0.829 ! regulation of release of cytochrome c from mitochondria GO:0090199 32 32 1.000 0.30476645 0.72044374 1.000 1.000 0.804 ! positive regulation of reactive oxygen species metabolic process GO:2000379 32 32 1.000 0.30476645 0.71969328 1.000 1.000 0.832 ! protein N-linked glycosylation GO:0006487 100 100 2.000 0.31179513 0.73552504 0.31179513 1.000 0.784 ! positive regulation of DNA metabolic process GO:0051054 100 100 2.000 0.31179513 0.73476046 1.000 1.000 0.889 ! regulation of immunoglobulin production GO:0002637 33 33 1.000 0.3126266 0.73595482 1.000 1.000 0.849 ! regulation of B cell mediated immunity GO:0002712 33 33 1.000 0.3126266 0.73519138 1.000 1.000 0.868 ! regulation of organ formation GO:0003156 33 33 1.000 0.3126266 0.73442953 1.000 1.000 0.864 ! C21-steroid hormone metabolic process GO:0008207 33 33 1.000 0.3126266 0.73366925 1.000 1.000 0.787 ! phospholipid transport GO:0015914 33 33 1.000 0.3126266 0.73291054 1.000 1.000 0.768 ! peptidyl-threonine phosphorylation GO:0018107 33 33 1.000 0.3126266 0.7321534 0.3126266 1.000 0.808 ! neural tube patterning GO:0021532 33 33 1.000 0.3126266 0.73139783 1.000 1.000 0.828 ! hindbrain morphogenesis GO:0021575 33 33 1.000 0.3126266 0.73064381 1.000 1.000 0.834 ! histone lysine methylation GO:0034968 33 33 1.000 0.3126266 0.72989134 1.000 1.000 0.688 ! photoreceptor cell development GO:0042461 33 33 1.000 0.3126266 0.72914043 1.000 1.000 0.735 ! positive regulation of blood pressure GO:0045777 33 33 1.000 0.3126266 0.72839105 1.000 1.000 0.852 ! thymus development GO:0048538 33 33 1.000 0.3126266 0.72764322 1.000 1.000 0.819 ! dendrite morphogenesis GO:0048813 33 33 1.000 0.3126266 0.72689692 1.000 1.000 0.730 ! head morphogenesis GO:0060323 33 33 1.000 0.3126266 0.72615215 0.3126266 1.000 0.815 ! signal transduction by p53 class mediator resulting in induction of apoptosis GO:0072332 34 33 1.000 0.3126266 0.7254089 0.3126266 1.000 0.760 ! regulation of DNA replication GO:0006275 101 101 2.000 0.3159485 0.73236734 1.000 1.000 0.946 ! neurotransmitter transport GO:0006836 101 101 2.000 0.3159485 0.73161926 0.3159485 1.000 0.946 ! protein complex disassembly GO:0043241 101 101 2.000 0.3159485 0.73087271 0.3159485 1.000 0.661 ! positive regulation of leukocyte proliferation GO:0070665 101 101 2.000 0.3159485 0.73012768 1.000 1.000 0.891 ! regulation of neurotransmitter levels GO:0001505 102 102 2.000 0.32009627 0.73895951 0.32009627 1.000 0.946 ! vesicle organization GO:0016050 103 102 2.000 0.32009627 0.73820778 0.68681712 1.000 0.946 ! response to vitamin A GO:0033189 102 102 2.000 0.32009627 0.73745756 1.000 1.000 0.946 ! response to interferon-gamma GO:0034341 102 102 2.000 0.32009627 0.73670888 0.32009627 1.000 0.946 ! neuromuscular junction development GO:0007528 34 34 1.000 0.32039831 0.73665615 0.32039831 1.000 0.760 ! drug metabolic process GO:0017144 34 34 1.000 0.32039831 0.73590979 1.000 1.000 0.766 ! negative regulation of type I interferon production GO:0032480 34 34 1.000 0.32039831 0.73516495 1.000 1.000 0.666 ! cell-cell signaling involved in cell fate commitment GO:0045168 34 34 1.000 0.32039831 0.73442161 1.000 1.000 0.856 ! negative regulation of chromosome organization GO:2001251 34 34 1.000 0.32039831 0.73367977 1.000 1.000 0.855 ! positive regulation of cellular catabolic process GO:0031331 103 103 2.000 0.32423803 0.74172312 0.69037182 1.000 0.946 ! synapse organization GO:0050808 103 103 2.000 0.32423803 0.74097541 0.32423803 1.000 0.946 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 35 35 1.000 0.32808258 0.74900626 1.000 1.000 0.655 ! salivary gland development GO:0007431 35 35 1.000 0.32808258 0.74825273 1.000 1.000 0.846 ! lactation GO:0007595 35 35 1.000 0.32808258 0.74750072 1.000 1.000 0.842 ! phototransduction GO:0007602 35 35 1.000 0.32808258 0.74675022 0.32808258 1.000 0.577 ! positive regulation of B cell proliferation GO:0030890 35 35 1.000 0.32808258 0.74600122 1.000 1.000 0.842 ! embryonic camera-type eye development GO:0031076 35 35 1.000 0.32808258 0.74525372 0.32808258 1.000 0.857 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 35 35 1.000 0.32808258 0.74450772 0.32808258 1.000 0.759 ! regulation of interleukin-1 beta production GO:0032651 35 35 1.000 0.32808258 0.74376321 1.000 1.000 0.860 ! T cell proliferation GO:0042098 35 35 1.000 0.32808258 0.74302019 0.32808258 1.000 0.775 ! embryonic digestive tract development GO:0048566 35 35 1.000 0.32808258 0.74227866 1.000 1.000 0.866 ! cardiac muscle cell development GO:0055013 35 35 1.000 0.32808258 0.7415386 1.000 1.000 0.853 ! regulation of heart growth GO:0060420 35 35 1.000 0.32808258 0.74080001 0.32808258 1.000 0.872 ! neuron death GO:0070997 35 35 1.000 0.32808258 0.7400629 1.000 1.000 0.755 ! embryonic epithelial tube formation GO:0001838 104 104 2.000 0.32837339 0.73998258 1.000 1.000 0.946 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 104 104 2.000 0.32837339 0.73924774 0.32837339 1.000 0.946 ! detection of external stimulus GO:0009581 104 104 2.000 0.32837339 0.73851436 0.32837339 1.000 0.946 ! B cell activation GO:0042113 104 104 2.000 0.32837339 0.73778243 1.000 1.000 0.946 ! regulation of protein ubiquitination GO:0031396 179 179 3.000 0.32880535 0.73802151 0.87020853 1.000 0.946 ! epithelial tube formation GO:0072175 105 105 2.000 0.33250197 0.74558058 1.000 1.000 0.946 ! skeletal system morphogenesis GO:0048705 181 181 3.000 0.3349793 0.75039335 0.60838763 1.000 0.946 ! very long-chain fatty acid metabolic process GO:0000038 36 36 1.000 0.33568039 0.75122157 0.33568039 1.000 0.796 ! eye photoreceptor cell differentiation GO:0001754 36 36 1.000 0.33568039 0.75048073 1.000 1.000 0.799 ! coenzyme catabolic process GO:0009109 36 36 1.000 0.33568039 0.74974134 0.33568039 1.000 0.816 ! peptidyl-threonine modification GO:0018210 36 36 1.000 0.33568039 0.7490034 0.33568039 1.000 0.813 ! cellular response to UV GO:0034644 37 36 1.000 0.33568039 0.74826692 0.33568039 1.000 0.808 ! cellular response to drug GO:0035690 36 36 1.000 0.33568039 0.74753188 1.000 1.000 0.846 ! bone remodeling GO:0046849 36 36 1.000 0.33568039 0.74679829 1.000 1.000 0.811 ! regulation of cellular response to insulin stimulus GO:1900076 37 36 1.000 0.33568039 0.74606613 1.000 1.000 0.847 ! positive regulation of apoptotic signaling pathway GO:2001235 36 36 1.000 0.33568039 0.74533541 0.33568039 1.000 0.808 ! catecholamine metabolic process GO:0006584 37 37 1.000 0.34319271 0.76126994 1.000 1.000 0.846 GO:0009712|catechol-containing compound metabolic process, GO:0034311|diol metabolic process, ! vesicle coating GO:0006901 37 37 1.000 0.34319271 0.76052579 0.34319271 1.000 0.691 ! visual learning GO:0008542 37 37 1.000 0.34319271 0.75978309 0.34319271 1.000 0.834 ! regulation of Notch signaling pathway GO:0008593 37 37 1.000 0.34319271 0.75904184 1.000 1.000 0.772 ! catechol-containing compound metabolic process GO:0009712 37 37 1.000 0.34319271 0.76126994 1.000 1.000 0.846 GO:0034311|diol metabolic process, GO:0006584|catecholamine metabolic process, ! fatty acid transport GO:0015908 37 37 1.000 0.34319271 0.75830203 1.000 1.000 0.840 ! actin cytoskeleton reorganization GO:0031532 37 37 1.000 0.34319271 0.75756366 0.34319271 1.000 0.746 ! diol metabolic process GO:0034311 37 37 1.000 0.34319271 0.76126994 1.000 1.000 0.846 GO:0009712|catechol-containing compound metabolic process, GO:0006584|catecholamine metabolic process, ! pteridine-containing compound metabolic process GO:0042558 37 37 1.000 0.34319271 0.75682673 1.000 1.000 0.807 ! regulation of epidermis development GO:0045682 37 37 1.000 0.34319271 0.75609124 0.34319271 1.000 0.809 ! regulation of fatty acid oxidation GO:0046320 37 37 1.000 0.34319271 0.75535717 1.000 1.000 0.787 ! epidermis morphogenesis GO:0048730 37 37 1.000 0.34319271 0.75462452 0.34319271 1.000 0.821 ! face development GO:0060324 37 37 1.000 0.34319271 0.7538933 0.34319271 1.000 0.817 ! protein K48-linked ubiquitination GO:0070936 37 37 1.000 0.34319271 0.75316349 1.000 1.000 0.384 ! activation of phospholipase C activity GO:0007202 108 108 2.000 0.34484336 0.75605405 0.70755201 1.000 0.946 ! regulation of developmental growth GO:0048638 108 108 2.000 0.34484336 0.75532356 0.70755201 1.000 0.946 ! transcription initiation from RNA polymerase II promoter GO:0006367 185 185 3.000 0.34731888 0.76001148 0.87883791 1.000 0.946 ! vesicle targeting GO:0006903 38 38 1.000 0.3506205 0.76649631 0.3506205 1.000 0.692 ! mitochondrial membrane organization GO:0007006 39 38 1.000 0.3506205 0.76575787 1.000 1.000 0.789 ! forebrain generation of neurons GO:0021872 38 38 1.000 0.3506205 0.76502086 1.000 1.000 0.862 ! muscle filament sliding GO:0030049 38 38 1.000 0.3506205 0.76428526 1.000 1.000 0.682 GO:0033275|actin-myosin filament sliding, ! actin-myosin filament sliding GO:0033275 38 38 1.000 0.3506205 0.76428526 1.000 1.000 0.682 GO:0030049|muscle filament sliding, ! actin filament bundle assembly GO:0051017 38 38 1.000 0.3506205 0.76355107 0.3506205 1.000 0.711 ! anatomical structure maturation GO:0071695 38 38 1.000 0.3506205 0.7628183 0.3506205 1.000 0.840 ! MAPK cascade GO:0000165 187 187 3.000 0.3534815 0.76830542 0.88158556 1.000 0.946 ! acute-phase response GO:0006953 39 39 1.000 0.35796469 0.77730456 0.35796469 1.000 0.583 ! respiratory gaseous exchange GO:0007585 39 39 1.000 0.35796469 0.77656073 1.000 1.000 0.659 ! secondary metabolic process GO:0019748 39 39 1.000 0.35796469 0.77581832 1.000 1.000 0.811 ! positive regulation of developmental growth GO:0048639 39 39 1.000 0.35796469 0.77507732 1.000 1.000 0.851 ! regulation of excitatory postsynaptic membrane potential GO:0060079 39 39 1.000 0.35796469 0.77433775 0.35796469 1.000 0.864 ! digestive system development GO:0055123 112 112 2.000 0.36118204 0.78055262 1.000 1.000 0.946 ! lymphocyte homeostasis GO:0002260 40 40 1.000 0.36522623 0.78854083 1.000 1.000 0.848 ! apoptotic mitochondrial changes GO:0008637 40 40 1.000 0.36522623 0.78779055 1.000 1.000 0.829 ! receptor internalization GO:0031623 40 40 1.000 0.36522623 0.7870417 1.000 1.000 0.836 ! regulation of interleukin-2 production GO:0032663 40 40 1.000 0.36522623 0.78629428 1.000 1.000 0.859 ! regulation of cell adhesion mediated by integrin GO:0033628 41 40 1.000 0.36522623 0.78554827 1.000 1.000 0.865 ! regulation of tissue remodeling GO:0034103 40 40 1.000 0.36522623 0.78480367 1.000 1.000 0.870 ! response to axon injury GO:0048678 40 40 1.000 0.36522623 0.78406049 1.000 1.000 0.817 ! embryonic limb morphogenesis GO:0030326 113 113 2.000 0.36524373 0.78335622 1.000 1.000 0.946 GO:0035113|embryonic appendage morphogenesis, ! embryonic appendage morphogenesis GO:0035113 113 113 2.000 0.36524373 0.78335622 1.000 1.000 0.946 GO:0030326|embryonic limb morphogenesis, ! tube formation GO:0035148 113 113 2.000 0.36524373 0.78261581 1.000 1.000 0.946 ! cellular response to insulin stimulus GO:0032869 192 191 3.000 0.36578515 0.78303581 1.000 1.000 0.946 ! positive regulation of phospholipase C activity GO:0010863 114 114 2.000 0.36929559 0.78980481 0.72692046 1.000 0.946 ! regulation of DNA recombination GO:0000018 41 41 1.000 0.37240605 0.79570642 1.000 1.000 0.848 ! regulation of cytokine production involved in immune response GO:0002718 41 41 1.000 0.37240605 0.79495717 1.000 1.000 0.877 ! membrane budding GO:0006900 41 41 1.000 0.37240605 0.79420932 0.37240605 1.000 0.733 ! body morphogenesis GO:0010171 41 41 1.000 0.37240605 0.79346289 0.37240605 1.000 0.818 ! cell differentiation in spinal cord GO:0021515 42 41 1.000 0.37240605 0.79271785 1.000 1.000 0.789 ! forebrain cell migration GO:0021885 41 41 1.000 0.37240605 0.79197421 1.000 1.000 0.877 ! regulation of interleukin-12 production GO:0032655 41 41 1.000 0.37240605 0.79123197 0.37240605 1.000 0.858 ! regulation of interleukin-8 production GO:0032677 41 41 1.000 0.37240605 0.79049112 1.000 1.000 0.873 ! negative regulation of mitotic cell cycle GO:0045930 41 41 1.000 0.37240605 0.78975165 1.000 1.000 0.745 ! regulation of alpha-beta T cell differentiation GO:0046637 41 41 1.000 0.37240605 0.78901356 1.000 1.000 0.877 ! regulation of phagocytosis GO:0050764 41 41 1.000 0.37240605 0.78827685 1.000 1.000 0.853 ! positive regulation of axonogenesis GO:0050772 41 41 1.000 0.37240605 0.78754152 1.000 1.000 0.795 ! ventricular cardiac muscle tissue morphogenesis GO:0055010 41 41 1.000 0.37240605 0.78680756 1.000 1.000 0.863 ! cellular response to light stimulus GO:0071482 42 41 1.000 0.37240605 0.78607496 0.37240605 1.000 0.827 ! sulfur amino acid metabolic process GO:0000096 42 42 1.000 0.37950505 0.80031437 1.000 1.000 0.827 ! visual behavior GO:0007632 42 42 1.000 0.37950505 0.79957058 0.37950505 1.000 0.832 ! ribonucleoside monophosphate metabolic process GO:0009161 42 42 1.000 0.37950505 0.79882818 1.000 1.000 0.855 ! anterior/posterior axis specification GO:0009948 42 42 1.000 0.37950505 0.79808715 0.37950505 1.000 0.852 ! photoreceptor cell differentiation GO:0046530 42 42 1.000 0.37950505 0.7973475 1.000 1.000 0.809 ! cofactor catabolic process GO:0051187 42 42 1.000 0.37950505 0.79660921 0.37950505 1.000 0.837 ! demethylation GO:0070988 42 42 1.000 0.37950505 0.79587229 1.000 1.000 0.819 ! post-translational protein modification GO:0043687 197 196 3.000 0.38110995 0.7984993 0.65161122 1.000 0.946 ! leukocyte homeostasis GO:0001776 43 43 1.000 0.38652415 0.80909533 1.000 1.000 0.856 ! regulation of pH GO:0006885 43 43 1.000 0.38652415 0.80834893 1.000 1.000 0.784 ! pituitary gland development GO:0021983 43 43 1.000 0.38652415 0.80760391 1.000 1.000 0.867 ! androgen receptor signaling pathway GO:0030521 43 43 1.000 0.38652415 0.80686026 1.000 1.000 0.697 ! adherens junction organization GO:0034332 43 43 1.000 0.38652415 0.80611797 0.38652415 1.000 0.597 ! regulation of steroid biosynthetic process GO:0050810 43 43 1.000 0.38652415 0.80537706 1.000 1.000 0.867 ! inner ear receptor cell differentiation GO:0060113 43 43 1.000 0.38652415 0.8046375 1.000 1.000 0.814 ! mammary gland development GO:0030879 120 120 2.000 0.39338465 0.8181679 0.74501209 1.000 0.946 ! ATP metabolic process GO:0046034 121 120 2.000 0.39338465 0.81741797 0.74501209 1.000 0.946 ! acetyl-CoA metabolic process GO:0006084 44 44 1.000 0.39346423 0.81683462 0.39346423 1.000 0.840 ! smooth muscle contraction GO:0006939 44 44 1.000 0.39346423 0.81608729 1.000 1.000 0.849 ! positive regulation of phosphatidylinositol 3-kinase cascade GO:0014068 44 44 1.000 0.39346423 0.81534132 1.000 1.000 0.869 ! sterol transport GO:0015918 44 44 1.000 0.39346423 0.81459672 1.000 1.000 0.849 GO:0030301|cholesterol transport, ! cholesterol transport GO:0030301 44 44 1.000 0.39346423 0.81459672 1.000 1.000 0.849 GO:0015918|sterol transport, ! modification of morphology or physiology of other organism GO:0035821 44 44 1.000 0.39346423 0.81385347 1.000 1.000 0.874 GO:0051817|modification of morphology or physiology of other organism involved in symbiotic interaction, ! fluid transport GO:0042044 44 44 1.000 0.39346423 0.81311158 1.000 1.000 0.808 ! modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 44 44 1.000 0.39346423 0.81385347 1.000 1.000 0.874 GO:0035821|modification of morphology or physiology of other organism, ! regulation of postsynaptic membrane potential GO:0060078 44 44 1.000 0.39346423 0.81237104 0.39346423 1.000 0.873 ! detection of light stimulus GO:0009583 45 45 1.000 0.40032618 0.82578659 0.40032618 1.000 0.674 ! positive regulation of cellular carbohydrate metabolic process GO:0010676 46 45 1.000 0.40032618 0.82503587 1.000 1.000 0.866 ! cranial nerve development GO:0021545 45 45 1.000 0.40032618 0.82428652 1.000 1.000 0.862 ! peptide hormone secretion GO:0030072 45 45 1.000 0.40032618 0.82353853 1.000 1.000 0.817 ! positive regulation of insulin secretion GO:0032024 45 45 1.000 0.40032618 0.82279189 1.000 1.000 0.851 ! actin-mediated cell contraction GO:0070252 45 45 1.000 0.40032618 0.82204661 1.000 1.000 0.734 ! peptidyl-lysine modification GO:0018205 122 122 2.000 0.40132331 0.82334838 0.75077353 1.000 0.946 ! macromolecular complex disassembly GO:0032984 122 122 2.000 0.40132331 0.82260394 0.40132331 1.000 0.749 ! maintenance of location GO:0051235 122 122 2.000 0.40132331 0.82186084 0.75077353 1.000 0.946 ! positive regulation of phospholipase activity GO:0010518 123 123 2.000 0.40527446 0.82920325 0.75360549 1.000 0.946 ! G1 phase of mitotic cell cycle GO:0000080 46 46 1.000 0.40711089 0.83220954 0.40711089 1.000 0.667 ! regulation of sodium ion transport GO:0002028 46 46 1.000 0.40711089 0.83145981 1.000 1.000 0.850 ! regulation of smooth muscle contraction GO:0006940 46 46 1.000 0.40711089 0.83071142 1.000 1.000 0.860 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 47 46 1.000 0.40711089 0.82996437 0.40711089 1.000 0.801 ! histone methylation GO:0016571 47 46 1.000 0.40711089 0.82921867 1.000 1.000 0.789 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 46 1.000 0.40711089 0.82847431 1.000 1.000 0.875 ! dicarboxylic acid metabolic process GO:0043648 46 46 1.000 0.40711089 0.82773129 0.40711089 1.000 0.853 ! cellular response to steroid hormone stimulus GO:0071383 46 46 1.000 0.40711089 0.82698959 0.40711089 1.000 0.864 ! GTP catabolic process GO:0006184 124 124 2.000 0.40921317 0.8305159 0.40921317 1.000 0.712 ! eye morphogenesis GO:0048592 125 125 2.000 0.41313923 0.83773401 0.75917371 1.000 0.946 ! regulation of smoothened signaling pathway GO:0008589 47 47 1.000 0.41381921 0.83836295 1.000 1.000 0.804 ! regulation of mitochondrion organization GO:0010821 48 47 1.000 0.41381921 0.83761441 1.000 1.000 0.842 ! hormone biosynthetic process GO:0042446 47 47 1.000 0.41381921 0.83686721 1.000 1.000 0.811 ! skeletal muscle fiber development GO:0048741 47 47 1.000 0.41381921 0.83612134 0.41381921 1.000 0.817 ! JAK-STAT cascade GO:0007259 48 48 1.000 0.42045199 0.8487664 1.000 1.000 0.830 ! G1 phase GO:0051318 48 48 1.000 0.42045199 0.84801127 0.42045199 1.000 0.669 ! regulation of cardiac muscle contraction GO:0055117 48 48 1.000 0.42045199 0.84725748 1.000 1.000 0.881 ! epithelial to mesenchymal transition GO:0001837 49 49 1.000 0.4270101 0.85970861 0.4270101 1.000 0.872 ! embryonic heart tube morphogenesis GO:0003143 49 49 1.000 0.4270101 0.85894578 1.000 1.000 0.874 ! ATP biosynthetic process GO:0006754 50 49 1.000 0.4270101 0.8581843 0.4270101 1.000 0.780 ! regulation of chemokine production GO:0032642 49 49 1.000 0.4270101 0.85742417 1.000 1.000 0.882 ! mechanoreceptor differentiation GO:0042490 49 49 1.000 0.4270101 0.85666539 1.000 1.000 0.837 ! 'de novo' posttranslational protein folding GO:0051084 49 49 1.000 0.4270101 0.85590795 0.4270101 1.000 0.203 ! protein homotetramerization GO:0051289 49 49 1.000 0.4270101 0.85515185 0.4270101 1.000 0.828 ! cellular response to hydrogen peroxide GO:0070301 49 49 1.000 0.4270101 0.85439708 1.000 1.000 0.849 ! regulation of phospholipase activity GO:0010517 129 129 2.000 0.42871266 0.85704727 0.76993726 1.000 0.946 ! head development GO:0060322 50 50 1.000 0.43349435 0.86584291 0.43349435 1.000 0.843 ! neural precursor cell proliferation GO:0061351 50 50 1.000 0.43349435 0.86508072 0.43349435 1.000 0.841 ! cellular response to vitamin A GO:0071299 50 50 1.000 0.43349435 0.86431987 1.000 1.000 0.865 GO:0071300|cellular response to retinoic acid, ! cellular response to retinoic acid GO:0071300 50 50 1.000 0.43349435 0.86431987 1.000 1.000 0.865 GO:0071299|cellular response to vitamin A, ! positive regulation of canonical Wnt receptor signaling pathway GO:0090263 51 50 1.000 0.43349435 0.86356037 1.000 1.000 0.820 ! positive regulation of lipase activity GO:0060193 131 131 2.000 0.43641812 0.86862149 0.77513814 1.000 0.946 ! activation of MAPKK activity GO:0000186 51 51 1.000 0.43990559 0.87479471 0.43990559 1.000 0.797 ! branching involved in ureteric bud morphogenesis GO:0001658 51 51 1.000 0.43990559 0.87402802 0.43990559 1.000 0.871 ! regulation of B cell proliferation GO:0030888 51 51 1.000 0.43990559 0.87326267 1.000 1.000 0.861 ! epidermal growth factor receptor signaling pathway GO:0007173 133 132 2.000 0.44024988 0.87318152 0.44024988 1.000 0.946 ! regulation of myeloid cell differentiation GO:0045637 133 133 2.000 0.44406743 0.87998327 0.78022202 1.000 0.946 ! smoothened signaling pathway GO:0007224 52 52 1.000 0.44624462 0.88352538 1.000 1.000 0.741 ! regulation of ion transmembrane transporter activity GO:0032412 52 52 1.000 0.44624462 0.88275441 1.000 1.000 0.867 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 53 52 1.000 0.44624462 0.88198479 1.000 1.000 0.876 ! lymphocyte proliferation GO:0046651 52 52 1.000 0.44624462 0.88121651 0.44624462 1.000 0.854 ! positive regulation of peptide hormone secretion GO:0090277 52 52 1.000 0.44624462 0.88044957 1.000 1.000 0.865 ! amine transport GO:0015837 134 134 2.000 0.4478706 0.88288926 0.7827209 1.000 0.946 ! production of molecular mediator of immune response GO:0002440 53 53 1.000 0.45251226 0.89126438 1.000 1.000 0.865 ! positive regulation of peptide secretion GO:0002793 53 53 1.000 0.45251226 0.89049071 1.000 1.000 0.867 ! multicellular organism growth GO:0035264 53 53 1.000 0.45251226 0.88971839 0.45251226 1.000 0.799 ! apoptotic signaling pathway GO:0097190 53 53 1.000 0.45251226 0.8889474 1.000 1.000 0.791 ! regulation of apoptotic signaling pathway GO:2001233 53 53 1.000 0.45251226 0.88817775 0.45251226 1.000 0.848 ! viral infectious cycle GO:0019058 137 136 2.000 0.45543315 0.89313749 0.78763416 1.000 0.798 ! positive regulation of cell projection organization GO:0031346 139 136 2.000 0.45543315 0.89236555 1.000 1.000 0.946 ! lymphocyte activation involved in immune response GO:0002285 54 54 1.000 0.45870931 0.89800864 1.000 1.000 0.879 ! regulation of acute inflammatory response GO:0002673 54 54 1.000 0.45870931 0.89723383 1.000 1.000 0.866 ! negative regulation of immune effector process GO:0002698 55 54 1.000 0.45870931 0.89646035 1.000 1.000 0.886 ! 'de novo' protein folding GO:0006458 54 54 1.000 0.45870931 0.89568821 0.45870931 1.000 0.354 ! protein lipidation GO:0006497 54 54 1.000 0.45870931 0.89491739 1.000 1.000 0.641 ! nucleus organization GO:0006997 54 54 1.000 0.45870931 0.8941479 1.000 1.000 0.812 ! mononuclear cell proliferation GO:0032943 54 54 1.000 0.45870931 0.89337973 0.45870931 1.000 0.859 ! positive regulation of translation GO:0045727 55 54 1.000 0.45870931 0.89261288 1.000 1.000 0.786 ! positive regulation of JAK-STAT cascade GO:0046427 55 54 1.000 0.45870931 0.89184735 1.000 1.000 0.876 ! digestive tract morphogenesis GO:0048546 54 54 1.000 0.45870931 0.89108313 1.000 1.000 0.888 ! negative regulation of immune response GO:0050777 55 54 1.000 0.45870931 0.89032021 1.000 1.000 0.877 ! fat-soluble vitamin metabolic process GO:0006775 55 55 1.000 0.46483656 0.90144095 0.46483656 1.000 0.823 ! regulation of phosphatidylinositol 3-kinase cascade GO:0014066 55 55 1.000 0.46483656 0.90067049 1.000 1.000 0.876 ! central nervous system neuron development GO:0021954 55 55 1.000 0.46483656 0.89990135 0.46483656 1.000 0.865 ! positive regulation of B cell activation GO:0050871 55 55 1.000 0.46483656 0.89913351 1.000 1.000 0.878 ! homophilic cell adhesion GO:0007156 140 139 2.000 0.46666523 0.90190117 0.46666523 1.000 0.000702 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 140 2.000 0.47037889 0.90830403 0.47037889 1.000 0.946 ! associative learning GO:0008306 56 56 1.000 0.47089479 0.90852636 0.47089479 1.000 0.876 ! protein secretion GO:0009306 56 56 1.000 0.47089479 0.90775381 1.000 1.000 0.786 ! cholesterol homeostasis GO:0042632 56 56 1.000 0.47089479 0.90698256 1.000 1.000 0.867 ! mesoderm formation GO:0001707 57 57 1.000 0.47688477 0.91774004 1.000 1.000 0.873 ! phenol-containing compound metabolic process GO:0018958 57 57 1.000 0.47688477 0.91696164 1.000 1.000 0.863 ! sensory perception of pain GO:0019233 57 57 1.000 0.47688477 0.91618455 1.000 1.000 0.844 ! regulation of transmembrane transporter activity GO:0022898 57 57 1.000 0.47688477 0.91540878 1.000 1.000 0.875 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 57 57 1.000 0.47688477 0.91463432 0.47688477 1.000 0.832 ! neuron fate commitment GO:0048663 57 57 1.000 0.47688477 0.91386117 1.000 1.000 0.864 ! establishment of vesicle localization GO:0051650 57 57 1.000 0.47688477 0.91308933 0.47688477 1.000 0.820 ! sterol homeostasis GO:0055092 57 57 1.000 0.47688477 0.91231879 1.000 1.000 0.866 ! leukocyte proliferation GO:0070661 57 57 1.000 0.47688477 0.91154955 0.47688477 1.000 0.864 ! endosome transport GO:0016197 142 142 2.000 0.47775986 0.91245291 0.80172042 1.000 0.693 ! regulation of striated muscle contraction GO:0006942 58 58 1.000 0.48280727 0.92131657 1.000 1.000 0.882 ! vacuole organization GO:0007033 59 58 1.000 0.48280727 0.9205417 1.000 1.000 0.748 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 58 58 1.000 0.48280727 0.91976813 1.000 1.000 0.854 ! positive regulation of cell-substrate adhesion GO:0010811 58 58 1.000 0.48280727 0.91899587 1.000 1.000 0.803 ! positive regulation of neuron projection development GO:0010976 59 58 1.000 0.48280727 0.9182249 1.000 1.000 0.853 ! positive regulation of JUN kinase activity GO:0043507 58 58 1.000 0.48280727 0.91745522 1.000 1.000 0.837 ! monovalent inorganic cation homeostasis GO:0055067 58 58 1.000 0.48280727 0.91668683 1.000 1.000 0.843 ! glutamine family amino acid metabolic process GO:0009064 59 59 1.000 0.48866305 0.92702856 0.48866305 1.000 0.864 ! lipoprotein biosynthetic process GO:0042158 59 59 1.000 0.48866305 0.92625345 1.000 1.000 0.707 ! locomotory behavior GO:0007626 146 146 2.000 0.49233305 0.93243025 0.49233305 1.000 0.946 ! regulation of neuron apoptosis GO:0043523 147 146 2.000 0.49233305 0.93165193 0.81059072 1.000 0.946 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 61 60 1.000 0.49445285 0.93488291 0.49445285 1.000 0.820 ! regulation of bone mineralization GO:0030500 60 60 1.000 0.49445285 0.93410384 1.000 1.000 0.862 ! negative regulation of cAMP biosynthetic process GO:0030818 60 60 1.000 0.49445285 0.93332607 1.000 1.000 0.847 ! negative regulation of myeloid cell differentiation GO:0045638 60 60 1.000 0.49445285 0.93254959 1.000 1.000 0.857 ! regulation of insulin secretion GO:0050796 148 148 2.000 0.4995235 0.94132982 0.81487665 1.000 0.946 ! purine nucleoside triphosphate biosynthetic process GO:0009145 62 61 1.000 0.50017741 0.94177923 0.50017741 1.000 0.825 ! protein deubiquitination GO:0016579 61 61 1.000 0.50017741 0.94099767 1.000 1.000 0.581 ! negative regulation of cyclic nucleotide biosynthetic process GO:0030803 61 61 1.000 0.50017741 0.94021741 1.000 1.000 0.849 ! negative regulation of cAMP metabolic process GO:0030815 61 61 1.000 0.50017741 0.93943844 1.000 1.000 0.848 ! regulation of defense response to virus GO:0050688 62 61 1.000 0.50017741 0.93866076 1.000 1.000 0.842 ! hormone metabolic process GO:0042445 149 149 2.000 0.50309434 0.9433539 0.81698328 1.000 0.946 ! acute inflammatory response GO:0002526 62 62 1.000 0.50583748 0.94771368 0.50583748 1.000 0.802 ! fatty acid oxidation GO:0019395 62 62 1.000 0.50583748 0.94693109 1.000 1.000 0.844 ! negative regulation of cyclic nucleotide metabolic process GO:0030800 62 62 1.000 0.50583748 0.9461498 1.000 1.000 0.849 ! regulation of histone modification GO:0031056 62 62 1.000 0.50583748 0.94536979 1.000 1.000 0.877 ! positive regulation of proteolysis GO:0045862 62 62 1.000 0.50583748 0.94459107 0.50583748 1.000 0.851 ! BMP signaling pathway GO:0030509 63 63 1.000 0.51143375 0.95425541 1.000 1.000 0.842 ! negative regulation of nucleotide biosynthetic process GO:0030809 63 63 1.000 0.51143375 0.95347066 1.000 1.000 0.854 ! regulation of epithelial cell differentiation GO:0030856 63 63 1.000 0.51143375 0.9526872 0.51143375 1.000 0.881 ! lipid oxidation GO:0034440 63 63 1.000 0.51143375 0.95190503 1.000 1.000 0.846 ! regulation of protein complex disassembly GO:0043244 63 63 1.000 0.51143375 0.95112414 1.000 1.000 0.826 ! negative regulation of DNA metabolic process GO:0051053 63 63 1.000 0.51143375 0.95034453 1.000 1.000 0.855 ! dendrite development GO:0016358 64 64 1.000 0.51696697 0.95983957 1.000 1.000 0.830 ! regulation of steroid metabolic process GO:0019218 64 64 1.000 0.51696697 0.9590541 1.000 1.000 0.885 ! inositol phosphate-mediated signaling GO:0048016 64 64 1.000 0.51696697 0.95826992 1.000 1.000 0.864 ! learning or memory GO:0007611 154 154 2.000 0.52070118 0.96440324 0.82716397 1.000 0.946 ! regulation of production of molecular mediator of immune response GO:0002700 65 65 1.000 0.52243782 0.96682983 1.000 1.000 0.888 ! induction of apoptosis by intracellular signals GO:0008629 66 65 1.000 0.52243782 0.96604122 0.52243782 1.000 0.838 ! regulation of receptor activity GO:0010469 65 65 1.000 0.52243782 0.9652539 1.000 1.000 0.868 ! nerve development GO:0021675 65 65 1.000 0.52243782 0.96446787 1.000 1.000 0.877 ! protein methylation GO:0006479 67 66 1.000 0.52784701 0.97366085 1.000 1.000 0.806 GO:0008213|protein alkylation, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 66 66 1.000 0.52784701 0.97286925 1.000 1.000 0.820 GO:0072474|signal transduction involved in mitotic cell cycle G1/S checkpoint, GO:0072413|signal transduction involved in mitotic cell cycle checkpoint, GO:0072431|signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint, ! protein alkylation GO:0008213 67 66 1.000 0.52784701 0.97366085 1.000 1.000 0.806 GO:0006479|protein methylation, ! ribonucleoside triphosphate biosynthetic process GO:0009201 67 66 1.000 0.52784701 0.97207894 0.52784701 1.000 0.839 ! negative regulation of protein complex assembly GO:0031333 66 66 1.000 0.52784701 0.97128992 1.000 1.000 0.844 ! odontogenesis of dentin-containing tooth GO:0042475 66 66 1.000 0.52784701 0.97050217 1.000 1.000 0.867 ! negative regulation of nucleotide metabolic process GO:0045980 66 66 1.000 0.52784701 0.96971571 1.000 1.000 0.858 ! regulation of organ growth GO:0046620 66 66 1.000 0.52784701 0.96893051 0.52784701 1.000 0.886 ! regulation of dendrite development GO:0050773 67 66 1.000 0.52784701 0.96814659 1.000 1.000 0.863 ! regulation of oxidoreductase activity GO:0051341 66 66 1.000 0.52784701 0.96736393 1.000 1.000 0.880 ! regulation of proteasomal protein catabolic process GO:0061136 66 66 1.000 0.52784701 0.96658254 0.52784701 1.000 0.842 ! signal transduction involved in mitotic cell cycle checkpoint GO:0072413 66 66 1.000 0.52784701 0.97286925 1.000 1.000 0.820 GO:0072474|signal transduction involved in mitotic cell cycle G1/S checkpoint, GO:0006977|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, GO:0072431|signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint, ! signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint GO:0072431 66 66 1.000 0.52784701 0.97286925 1.000 1.000 0.820 GO:0072474|signal transduction involved in mitotic cell cycle G1/S checkpoint, GO:0006977|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, GO:0072413|signal transduction involved in mitotic cell cycle checkpoint, ! signal transduction involved in mitotic cell cycle G1/S checkpoint GO:0072474 66 66 1.000 0.52784701 0.97286925 1.000 1.000 0.820 GO:0006977|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, GO:0072413|signal transduction involved in mitotic cell cycle checkpoint, GO:0072431|signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint, ! regulation of ossification GO:0030278 157 157 2.000 0.53106463 0.97168968 0.83299979 1.000 0.946 ! regulation of peptide hormone secretion GO:0090276 157 157 2.000 0.53106463 0.97090606 0.83299979 1.000 0.946 ! neural tube closure GO:0001843 67 67 1.000 0.53319524 0.9740158 1.000 1.000 0.853 ! memory GO:0007613 67 67 1.000 0.53319524 0.97323157 1.000 1.000 0.874 ! regulation of transcription factor import into nucleus GO:0042990 67 67 1.000 0.53319524 0.9724486 0.53319524 1.000 0.879 ! regulation of DNA binding GO:0051101 67 67 1.000 0.53319524 0.97166689 1.000 1.000 0.880 ! signal transduction involved in DNA integrity checkpoint GO:0072401 67 67 1.000 0.53319524 0.97088643 1.000 1.000 0.823 GO:0072422|signal transduction involved in DNA damage checkpoint, ! signal transduction involved in G1/S transition checkpoint GO:0072404 67 67 1.000 0.53319524 0.97010723 1.000 1.000 0.825 ! signal transduction involved in DNA damage checkpoint GO:0072422 67 67 1.000 0.53319524 0.97088643 1.000 1.000 0.823 GO:0072401|signal transduction involved in DNA integrity checkpoint, ! regulation of peptide secretion GO:0002791 159 159 2.000 0.53788889 0.97786215 0.83678098 1.000 0.946 GO:0090087|regulation of peptide transport, ! regulation of peptide transport GO:0090087 159 159 2.000 0.53788889 0.97786215 0.83678098 1.000 0.946 GO:0002791|regulation of peptide secretion, ! monocarboxylic acid transport GO:0015718 70 68 1.000 0.53848318 0.97815815 1.000 1.000 0.838 ! intracellular steroid hormone receptor signaling pathway GO:0030518 68 68 1.000 0.53848318 0.977375 1.000 1.000 0.803 ! regulation of type I interferon production GO:0032479 68 68 1.000 0.53848318 0.9765931 1.000 1.000 0.842 ! benzene-containing compound metabolic process GO:0042537 68 68 1.000 0.53848318 0.97581245 1.000 1.000 0.876 ! protein stabilization GO:0050821 68 68 1.000 0.53848318 0.97503304 1.000 1.000 0.841 ! tube closure GO:0060606 68 68 1.000 0.53848318 0.97425488 1.000 1.000 0.856 ! signal transduction involved in cell cycle checkpoint GO:0072395 68 68 1.000 0.53848318 0.97347797 1.000 1.000 0.826 ! telencephalon development GO:0021537 161 160 2.000 0.54127543 0.97774614 0.83863951 1.000 0.946 ! DNA catabolic process GO:0006308 69 69 1.000 0.54371151 0.98136465 1.000 1.000 0.844 ! diencephalon development GO:0021536 69 69 1.000 0.54371151 0.98058393 1.000 1.000 0.884 ! T cell costimulation GO:0031295 69 69 1.000 0.54371151 0.97980445 0.54371151 1.000 0.828 ! positive regulation of T cell proliferation GO:0042102 69 69 1.000 0.54371151 0.97902621 1.000 1.000 0.888 ! palate development GO:0060021 69 69 1.000 0.54371151 0.97824921 1.000 1.000 0.872 ! cellular response to radiation GO:0071478 70 69 1.000 0.54371151 0.97747343 0.54371151 1.000 0.867 ! regulation of cellular ketone metabolic process GO:0010565 162 162 2.000 0.54799711 0.98439734 1.000 1.000 0.946 ! adult locomotory behavior GO:0008344 70 70 1.000 0.54888091 0.98520429 0.54888091 1.000 0.853 ! nucleoside triphosphate biosynthetic process GO:0009142 71 70 1.000 0.54888091 0.98442485 0.54888091 1.000 0.851 ! regulation of fatty acid metabolic process GO:0019217 70 70 1.000 0.54888091 0.98364665 1.000 1.000 0.877 ! lymphocyte costimulation GO:0031294 70 70 1.000 0.54888091 0.98286968 0.54888091 1.000 0.832 ! carboxylic acid transport GO:0046942 165 163 2.000 0.55133215 0.98647985 0.84408968 1.000 0.946 ! nitrogen compound transport GO:0071705 163 163 2.000 0.55133215 0.98570187 0.84408968 1.000 0.946 ! negative regulation of organelle organization GO:0010639 164 164 2.000 0.55464993 0.99085216 1.000 1.000 0.946 ! organic acid transport GO:0015849 167 165 2.000 0.55795043 0.99596348 0.84762096 1.000 0.946 ! primary neural tube formation GO:0014020 72 72 1.000 0.55904551 0.9971331 1.000 1.000 0.861 ! regulation of cell-cell adhesion GO:0022407 73 72 1.000 0.55904551 0.99634919 0.55904551 1.000 0.884 ! positive regulation of Wnt receptor signaling pathway GO:0030177 73 72 1.000 0.55904551 0.99556651 1.000 1.000 0.863 ! regulation of JUN kinase activity GO:0043506 72 72 1.000 0.55904551 0.99478506 1.000 1.000 0.858 ! mitotic cell cycle G1/S transition DNA damage checkpoint GO:0031571 73 73 1.000 0.56404202 1.000 1.000 1.000 0.830 ! regulation of JAK-STAT cascade GO:0046425 74 73 1.000 0.56404202 1.000 1.000 1.000 0.882 ! G1/S transition of mitotic cell cycle GO:0000082 167 167 2.000 0.56449942 1.000 0.85107265 1.000 0.946 ! cognition GO:0050890 167 167 2.000 0.56449942 1.000 0.85107265 1.000 0.946 ! positive regulation of T cell activation GO:0050870 168 168 2.000 0.56774785 1.000 0.8527692 1.000 0.946 ! cellular component disassembly involved in apoptosis GO:0006921 74 74 1.000 0.56898219 1.000 1.000 1.000 0.823 ! neurotransmitter secretion GO:0007269 74 74 1.000 0.56898219 1.000 0.56898219 1.000 0.818 ! protein modification by small protein removal GO:0070646 74 74 1.000 0.56898219 1.000 1.000 1.000 0.613 ! myeloid leukocyte activation GO:0002274 75 75 1.000 0.57386666 1.000 0.57386666 1.000 0.880 ! regulation of lymphocyte mediated immunity GO:0002706 75 75 1.000 0.57386666 1.000 1.000 1.000 0.890 ! regulation of cell size GO:0008361 77 75 1.000 0.57386666 1.000 1.000 1.000 0.869 ! regulation of multicellular organism growth GO:0040014 75 75 1.000 0.57386666 1.000 0.57386666 1.000 0.880 ! inorganic anion transport GO:0015698 76 76 1.000 0.57869604 1.000 1.000 1.000 0.732 ! negative regulation of cell projection organization GO:0031345 76 76 1.000 0.57869604 1.000 0.57869604 1.000 0.869 ! organelle localization GO:0051640 175 174 2.000 0.58687216 1.000 0.86255217 1.000 0.946 ! regulation of myeloid leukocyte differentiation GO:0002761 78 78 1.000 0.58819203 1.000 1.000 1.000 0.882 ! positive regulation of binding GO:0051099 78 78 1.000 0.58819203 1.000 1.000 1.000 0.879 ! positive regulation of protein transport GO:0051222 178 175 2.000 0.58999835 1.000 1.000 1.000 0.946 ! formation of primary germ layer GO:0001704 79 79 1.000 0.59285985 1.000 1.000 1.000 0.884 ! positive regulation of nucleocytoplasmic transport GO:0046824 79 79 1.000 0.59285985 1.000 1.000 1.000 0.887 ! vesicle localization GO:0051648 79 79 1.000 0.59285985 1.000 0.59285985 1.000 0.859 ! membrane fusion GO:0061025 81 79 1.000 0.59285985 1.000 1.000 1.000 0.746 ! Golgi vesicle transport GO:0048193 177 177 2.000 0.59619818 1.000 0.59619818 1.000 0.785 ! positive regulation of cell cycle arrest GO:0071158 80 80 1.000 0.59747502 1.000 1.000 1.000 0.850 ! T cell activation GO:0042110 178 178 2.000 0.59927182 1.000 0.86871199 1.000 0.946 ! regulation of response to biotic stimulus GO:0002831 82 81 1.000 0.60203813 1.000 1.000 1.000 0.875 ! regulation of T cell differentiation GO:0045580 82 81 1.000 0.60203813 1.000 1.000 1.000 0.888 ! peptide metabolic process GO:0006518 82 82 1.000 0.60654976 1.000 1.000 1.000 0.789 ! mitotic cell cycle G1/S transition checkpoint GO:0031575 82 82 1.000 0.60654976 1.000 1.000 1.000 0.946 ! developmental growth involved in morphogenesis GO:0060560 83 83 1.000 0.6110105 1.000 0.6110105 1.000 0.888 ! positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 183 183 2.000 0.61437729 1.000 1.000 1.000 0.946 ! cell activation involved in immune response GO:0002263 84 84 1.000 0.61542091 1.000 1.000 1.000 0.889 GO:0002366|leukocyte activation involved in immune response, ! leukocyte activation involved in immune response GO:0002366 84 84 1.000 0.61542091 1.000 1.000 1.000 0.889 GO:0002263|cell activation involved in immune response, ! purine ribonucleotide biosynthetic process GO:0009152 85 84 1.000 0.61542091 1.000 0.61542091 1.000 0.869 ! viral genome expression GO:0019080 84 84 1.000 0.61542091 1.000 0.61542091 1.000 0.538 GO:0019083|viral transcription, ! viral transcription GO:0019083 84 84 1.000 0.61542091 1.000 0.61542091 1.000 0.538 GO:0019080|viral genome expression, ! maintenance of protein location in cell GO:0032507 84 84 1.000 0.61542091 1.000 0.61542091 1.000 0.867 ! positive regulation of protein secretion GO:0050714 84 84 1.000 0.61542091 1.000 1.000 1.000 0.885 ! T cell receptor signaling pathway GO:0050852 84 84 1.000 0.61542091 1.000 1.000 1.000 0.946 ! G1/S transition checkpoint GO:0071779 84 84 1.000 0.61542091 1.000 1.000 1.000 0.946 ! mRNA catabolic process GO:0006402 188 184 2.000 0.61734588 1.000 0.61734588 1.000 0.775 ! gonad development GO:0008406 184 184 2.000 0.61734588 1.000 1.000 1.000 0.946 ! translational termination GO:0006415 85 85 1.000 0.61978156 1.000 0.61978156 1.000 0.515 ! detection of abiotic stimulus GO:0009582 85 85 1.000 0.61978156 1.000 0.61978156 1.000 0.946 ! embryonic skeletal system morphogenesis GO:0048704 85 85 1.000 0.61978156 1.000 1.000 1.000 0.946 ! regulation of response to DNA damage stimulus GO:2001020 85 85 1.000 0.61978156 1.000 0.61978156 1.000 0.871 ! protein processing GO:0016485 86 86 1.000 0.62409301 1.000 0.62409301 1.000 0.946 ! keratinocyte differentiation GO:0030216 86 86 1.000 0.62409301 1.000 0.62409301 1.000 0.534 ! segmentation GO:0035282 86 86 1.000 0.62409301 1.000 0.62409301 1.000 0.882 ! one-carbon metabolic process GO:0006730 189 187 2.000 0.62614685 1.000 1.000 1.000 0.946 ! regulation of protein complex assembly GO:0043254 191 190 2.000 0.63479099 1.000 1.000 1.000 0.946 ! ear development GO:0043583 190 190 2.000 0.63479099 1.000 1.000 1.000 0.946 ! learning GO:0007612 90 90 1.000 0.64085773 1.000 0.64085773 1.000 0.886 ! phosphatidylinositol-mediated signaling GO:0048015 90 90 1.000 0.64085773 1.000 1.000 1.000 0.946 GO:0048017|inositol lipid-mediated signaling, ! inositol lipid-mediated signaling GO:0048017 90 90 1.000 0.64085773 1.000 1.000 1.000 0.946 GO:0048015|phosphatidylinositol-mediated signaling, ! response to ethanol GO:0045471 91 91 1.000 0.64493133 1.000 0.64493133 1.000 0.889 ! ribonucleoside triphosphate catabolic process GO:0009203 195 195 2.000 0.648851 1.000 0.648851 1.000 0.946 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! purine ribonucleoside triphosphate catabolic process GO:0009207 195 195 2.000 0.648851 1.000 0.648851 1.000 0.946 GO:0009203|ribonucleoside triphosphate catabolic process, ! antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 92 92 1.000 0.64895895 1.000 0.64895895 1.000 0.741 ! camera-type eye morphogenesis GO:0048593 92 92 1.000 0.64895895 1.000 1.000 1.000 0.946 ! negative regulation of neurogenesis GO:0050768 92 92 1.000 0.64895895 1.000 1.000 1.000 0.885 ! transition metal ion transport GO:0000041 93 93 1.000 0.65294111 1.000 0.65294111 1.000 0.765 ! regulation of phosphatase activity GO:0010921 93 93 1.000 0.65294111 1.000 0.65294111 1.000 0.640 ! regulation of Rho GTPase activity GO:0032319 93 93 1.000 0.65294111 1.000 1.000 1.000 0.946 ! purine nucleoside triphosphate catabolic process GO:0009146 197 197 2.000 0.65435425 1.000 0.65435425 1.000 0.946 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 94 94 1.000 0.65687831 1.000 0.65687831 1.000 0.741 GO:0002504|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 94 94 1.000 0.65687831 1.000 0.65687831 1.000 0.741 GO:0002495|antigen processing and presentation of peptide antigen via MHC class II, ! regulation of leukocyte mediated immunity GO:0002703 94 94 1.000 0.65687831 1.000 1.000 1.000 0.891 ! positive regulation of protein complex assembly GO:0031334 95 94 1.000 0.65687831 1.000 1.000 1.000 0.946 ! positive regulation of cytokine production GO:0001819 199 198 2.000 0.65708012 1.000 0.89562582 1.000 0.946 ! phosphatidylinositol biosynthetic process GO:0006661 95 95 1.000 0.66077107 1.000 1.000 1.000 0.946 ! coenzyme biosynthetic process GO:0009108 95 95 1.000 0.66077107 1.000 1.000 1.000 0.946 ! maintenance of location in cell GO:0051651 95 95 1.000 0.66077107 1.000 0.66077107 1.000 0.946 ! positive regulation of reproductive process GO:2000243 99 95 1.000 0.66077107 1.000 1.000 1.000 0.946 ! coenzyme metabolic process GO:0006732 200 200 2.000 0.66248055 1.000 0.89799448 1.000 0.946 ! negative regulation of neuron apoptosis GO:0043524 96 96 1.000 0.66461989 1.000 1.000 1.000 0.946 ! regulation of axonogenesis GO:0050770 96 96 1.000 0.66461989 1.000 1.000 1.000 0.946 ! chromatin remodeling GO:0006338 97 97 1.000 0.66842524 1.000 1.000 1.000 0.946 ! amino acid transport GO:0006865 97 97 1.000 0.66842524 1.000 0.66842524 1.000 0.946 ! cellular hormone metabolic process GO:0034754 97 97 1.000 0.66842524 1.000 1.000 1.000 0.946 ! nuclear export GO:0051168 97 97 1.000 0.66842524 1.000 0.66842524 1.000 0.724 ! cell-matrix adhesion GO:0007160 99 98 1.000 0.67218764 1.000 0.67218764 1.000 0.741 ! male gonad development GO:0008584 98 98 1.000 0.67218764 1.000 1.000 1.000 0.946 ! maintenance of protein location GO:0045185 98 98 1.000 0.67218764 1.000 0.67218764 1.000 0.946 ! positive regulation of intracellular protein transport GO:0090316 101 98 1.000 0.67218764 1.000 1.000 1.000 0.890 ! regulation of chromosome organization GO:0033044 99 99 1.000 0.67590754 1.000 1.000 1.000 0.889 ! cellular protein complex disassembly GO:0043624 99 99 1.000 0.67590754 1.000 0.67590754 1.000 0.644 ! protein maturation GO:0051604 99 99 1.000 0.67590754 1.000 0.67590754 1.000 0.946 ! ribonucleotide biosynthetic process GO:0009260 101 100 1.000 0.67958545 1.000 0.67958545 1.000 0.946 ! epidermal cell differentiation GO:0009913 101 101 1.000 0.68322182 1.000 0.68322182 1.000 0.700 ! negative regulation of cell cycle process GO:0010948 101 101 1.000 0.68322182 1.000 1.000 1.000 0.946 ! response to UV GO:0009411 103 102 1.000 0.68681712 1.000 0.68681712 1.000 0.946 ! gland morphogenesis GO:0022612 102 102 1.000 0.68681712 1.000 1.000 1.000 0.891 ! translational elongation GO:0006414 103 103 1.000 0.69037182 1.000 0.69037182 1.000 0.583 ! regulation of multi-organism process GO:0043900 104 103 1.000 0.69037182 1.000 1.000 1.000 0.946 ! digestive tract development GO:0048565 103 103 1.000 0.69037182 1.000 1.000 1.000 0.892 ! regulation of G1/S transition of mitotic cell cycle GO:2000045 103 103 1.000 0.69037182 1.000 1.000 1.000 0.946 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 105 105 1.000 0.69736121 1.000 0.69736121 1.000 0.610 ! T cell differentiation GO:0030217 105 105 1.000 0.69736121 1.000 1.000 1.000 0.946 ! lipid modification GO:0030258 105 105 1.000 0.69736121 1.000 1.000 1.000 0.946 ! regulation of cell shape GO:0008360 107 106 1.000 0.70079681 1.000 1.000 1.000 0.778 ! positive regulation of intracellular transport GO:0032388 109 106 1.000 0.70079681 1.000 1.000 1.000 0.946 ! cotranslational protein targeting to membrane GO:0006613 107 107 1.000 0.7041936 1.000 0.7041936 1.000 0.613 ! steroid biosynthetic process GO:0006694 107 107 1.000 0.7041936 1.000 1.000 1.000 0.946 ! protein targeting to ER GO:0045047 107 107 1.000 0.7041936 1.000 0.7041936 1.000 0.614 ! antigen receptor-mediated signaling pathway GO:0050851 107 107 1.000 0.7041936 1.000 1.000 1.000 0.946 ! macromolecule methylation GO:0043414 109 108 1.000 0.70755201 1.000 1.000 1.000 0.946 ! establishment of protein localization in endoplasmic reticulum GO:0072599 108 108 1.000 0.70755201 1.000 0.70755201 1.000 0.627 ! adult behavior GO:0030534 109 109 1.000 0.71087248 1.000 0.71087248 1.000 0.946 ! regulation of protein stability GO:0031647 110 109 1.000 0.71087248 1.000 1.000 1.000 0.946 ! cellular amino acid catabolic process GO:0009063 112 110 1.000 0.71415544 1.000 0.71415544 1.000 0.946 ! hindbrain development GO:0030902 113 112 1.000 0.72061048 1.000 1.000 1.000 0.946 ! regulation of dephosphorylation GO:0035303 114 113 1.000 0.7237834 1.000 0.7237834 1.000 0.747 ! immune response-activating cell surface receptor signaling pathway GO:0002429 114 114 1.000 0.72692046 1.000 1.000 1.000 0.946 ! mitochondrial transport GO:0006839 115 114 1.000 0.72692046 1.000 1.000 1.000 0.946 ! embryonic skeletal system development GO:0048706 114 114 1.000 0.72692046 1.000 1.000 1.000 0.946 ! ear morphogenesis GO:0042471 115 115 1.000 0.73002206 1.000 1.000 1.000 0.946 ! development of primary male sexual characteristics GO:0046546 115 115 1.000 0.73002206 1.000 1.000 1.000 0.946 ! S phase of mitotic cell cycle GO:0000084 116 116 1.000 0.73308862 1.000 0.73308862 1.000 0.946 ! cellular lipid catabolic process GO:0044242 116 116 1.000 0.73308862 1.000 1.000 1.000 0.946 ! establishment of organelle localization GO:0051656 117 116 1.000 0.73308862 1.000 0.73308862 1.000 0.946 ! phosphatidylinositol metabolic process GO:0046488 117 117 1.000 0.73612051 1.000 1.000 1.000 0.946 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 118 118 1.000 0.73911812 1.000 0.73911812 1.000 0.599 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 118 118 1.000 0.73911812 1.000 1.000 1.000 0.946 ! negative regulation of cell development GO:0010721 118 118 1.000 0.73911812 1.000 1.000 1.000 0.946 ! S phase GO:0051320 119 119 1.000 0.74208186 1.000 0.74208186 1.000 0.946 ! anion transport GO:0006820 120 120 1.000 0.74501209 1.000 1.000 1.000 0.946 ! methylation GO:0032259 122 120 1.000 0.74501209 1.000 1.000 1.000 0.946 ! cellular macromolecular complex disassembly GO:0034623 120 120 1.000 0.74501209 1.000 0.74501209 1.000 0.739 ! translational initiation GO:0006413 122 121 1.000 0.74790919 1.000 0.74790919 1.000 0.603 ! protein localization in endoplasmic reticulum GO:0070972 121 121 1.000 0.74790919 1.000 0.74790919 1.000 0.695 ! gastrulation GO:0007369 124 122 1.000 0.75077353 1.000 1.000 1.000 0.946 ! fibroblast growth factor receptor signaling pathway GO:0008543 122 122 1.000 0.75077353 1.000 0.75077353 1.000 0.946 ! amine catabolic process GO:0009310 125 123 1.000 0.75360549 1.000 0.75360549 1.000 0.946 ! male sex differentiation GO:0046661 123 123 1.000 0.75360549 1.000 1.000 1.000 0.946 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 125 125 1.000 0.75917371 1.000 1.000 1.000 0.946 ! skeletal muscle tissue development GO:0007519 130 128 1.000 0.76729211 1.000 0.76729211 1.000 0.946 ! cellular biogenic amine metabolic process GO:0006576 130 130 1.000 0.77255249 1.000 1.000 1.000 0.946 ! regulation of JNK cascade GO:0046328 131 131 1.000 0.77513814 1.000 1.000 1.000 0.946 ! DNA damage checkpoint GO:0000077 134 133 1.000 0.78022202 1.000 1.000 1.000 0.946 ! adaptive immune response GO:0002250 133 133 1.000 0.78022202 1.000 1.000 1.000 0.946 ! positive regulation of protein ubiquitination GO:0031398 134 134 1.000 0.7827209 1.000 0.7827209 1.000 0.946 ! skeletal muscle organ development GO:0060538 137 135 1.000 0.78519151 1.000 0.78519151 1.000 0.946 ! mitotic cell cycle checkpoint GO:0007093 137 137 1.000 0.79004918 1.000 1.000 1.000 0.946 ! cofactor biosynthetic process GO:0051188 137 137 1.000 0.79004918 1.000 1.000 1.000 0.946 ! cellular response to fibroblast growth factor stimulus GO:0044344 138 138 1.000 0.79243686 1.000 0.79243686 1.000 0.946 ! response to fibroblast growth factor stimulus GO:0071774 139 139 1.000 0.79479753 1.000 0.79479753 1.000 0.946 ! DNA integrity checkpoint GO:0031570 141 140 1.000 0.79713147 1.000 1.000 1.000 0.946 ! electron transport chain GO:0022900 141 141 1.000 0.799439 1.000 0.799439 1.000 0.748 ! defense response to bacterium GO:0042742 142 141 1.000 0.799439 1.000 1.000 1.000 0.761 ! regulation of stress-activated MAPK cascade GO:0032872 147 147 1.000 0.81274588 1.000 1.000 1.000 0.946 ! positive regulation of growth GO:0045927 148 147 1.000 0.81274588 1.000 1.000 1.000 0.946 ! regulation of stress-activated protein kinase signaling cascade GO:0070302 148 148 1.000 0.81487665 1.000 1.000 1.000 0.946 ! insulin receptor signaling pathway GO:0008286 151 150 1.000 0.81906607 1.000 1.000 1.000 0.946 ! positive regulation of GTPase activity GO:0043547 150 150 1.000 0.81906607 1.000 0.81906607 1.000 0.946 ! regulation of proteolysis GO:0030162 159 158 1.000 0.83490116 1.000 0.83490116 1.000 0.946 ! regulation of Ras GTPase activity GO:0032318 162 162 1.000 0.84229362 1.000 1.000 1.000 0.946 ! inner ear development GO:0048839 163 163 1.000 0.84408968 1.000 1.000 1.000 0.946 ! protein polyubiquitination GO:0000209 165 165 1.000 0.84762096 1.000 1.000 1.000 0.946 ! regulation of reproductive process GO:2000241 175 171 1.000 0.85774434 1.000 1.000 1.000 0.946 ! nuclear-transcribed mRNA catabolic process GO:0000956 176 174 1.000 0.86255217 1.000 0.86255217 1.000 0.745 ! regulation of synaptic transmission GO:0050804 176 175 1.000 0.86411857 1.000 1.000 1.000 0.946 ! organic acid catabolic process GO:0016054 179 177 1.000 0.86719828 1.000 0.86719828 1.000 0.946 GO:0046395|carboxylic acid catabolic process, ! carboxylic acid catabolic process GO:0046395 179 177 1.000 0.86719828 1.000 0.86719828 1.000 0.946 GO:0016054|organic acid catabolic process, ! regulation of binding GO:0051098 177 177 1.000 0.86719828 1.000 1.000 1.000 0.946 ! regulation of cellular component size GO:0032535 183 180 1.000 0.87168809 1.000 1.000 1.000 0.946 ! regulation of cell morphogenesis involved in differentiation GO:0010769 186 185 1.000 0.87883791 1.000 1.000 1.000 0.946 ! glycerophospholipid biosynthetic process GO:0046474 189 189 1.000 0.88427119 1.000 1.000 1.000 0.946 ! regulation of transmission of nerve impulse GO:0051969 200 197 1.000 0.89442104 1.000 1.000 1.000 0.946 ! autophagic vacuole assembly GO:0000045 25 24 0.000 1.000 1.000 1.000 1.000 0.365 ! mitotic sister chromatid segregation GO:0000070 50 48 0.000 1.000 1.000 1.000 1.000 0.748 ! regulation of transcription involved in G1/S phase of mitotic cell cycle GO:0000083 23 23 0.000 1.000 1.000 1.000 1.000 0.598 ! G2/M transition of mitotic cell cycle GO:0000086 127 127 0.000 1.000 1.000 1.000 1.000 0.798 ! M/G1 transition of mitotic cell cycle GO:0000216 79 79 0.000 1.000 1.000 1.000 1.000 0.791 ! mitotic prometaphase GO:0000236 86 85 0.000 1.000 1.000 1.000 1.000 0.743 ! spliceosome assembly GO:0000245 37 37 0.000 1.000 1.000 1.000 1.000 0.434 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 55 54 0.000 1.000 1.000 1.000 1.000 0.519 ! nuclear-transcribed mRNA poly(A) tail shortening GO:0000289 26 25 0.000 1.000 1.000 1.000 1.000 0.326 ! nuclear-transcribed mRNA catabolic process, exonucleolytic GO:0000291 26 26 0.000 1.000 1.000 1.000 1.000 0.296 GO:0043928|exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, ! RNA splicing, via transesterification reactions with bulged adenosine as nucleophile GO:0000377 196 196 0.000 1.000 1.000 1.000 1.000 0.609 GO:0000398|nuclear mRNA splicing, via spliceosome, ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 20 20 0.000 1.000 1.000 1.000 1.000 0.186 ! spliceosomal snRNP assembly GO:0000387 31 31 0.000 1.000 1.000 1.000 1.000 0.455 ! nuclear mRNA splicing, via spliceosome GO:0000398 196 196 0.000 1.000 1.000 1.000 1.000 0.609 GO:0000377|RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, ! nucleotide-excision repair, DNA damage removal GO:0000718 21 21 0.000 1.000 1.000 1.000 1.000 0.653 GO:0044349|DNA excision, ! telomere maintenance via recombination GO:0000722 27 27 0.000 1.000 1.000 1.000 1.000 0.716 ! telomere maintenance GO:0000723 58 58 0.000 1.000 1.000 1.000 1.000 0.837 ! double-strand break repair via homologous recombination GO:0000724 48 48 0.000 1.000 1.000 1.000 1.000 0.714 ! recombinational repair GO:0000725 50 49 0.000 1.000 1.000 1.000 1.000 0.717 ! sister chromatid segregation GO:0000819 53 51 0.000 1.000 1.000 1.000 1.000 0.768 ! retinoid metabolic process GO:0001523 42 42 0.000 1.000 1.000 1.000 1.000 0.769 ! ciliary or flagellar motility GO:0001539 24 24 0.000 1.000 1.000 1.000 1.000 0.0920 ! microtubule bundle formation GO:0001578 31 31 0.000 1.000 1.000 1.000 1.000 0.602 ! temperature homeostasis GO:0001659 24 24 0.000 1.000 1.000 1.000 1.000 0.824 ! gastrulation with mouth forming second GO:0001702 31 30 0.000 1.000 1.000 1.000 1.000 0.802 ! endoderm formation GO:0001706 26 26 0.000 1.000 1.000 1.000 1.000 0.792 ! cell fate specification GO:0001708 63 62 0.000 1.000 1.000 1.000 1.000 0.871 ! morphogenesis of a polarized epithelium GO:0001738 21 21 0.000 1.000 1.000 1.000 1.000 0.757 ! neural crest cell migration GO:0001755 40 40 0.000 1.000 1.000 1.000 1.000 0.845 ! somitogenesis GO:0001756 60 60 0.000 1.000 1.000 1.000 1.000 0.856 ! organ induction GO:0001759 20 20 0.000 1.000 1.000 1.000 1.000 0.783 ! mesonephros development GO:0001823 21 21 0.000 1.000 1.000 1.000 1.000 0.854 ! blastocyst development GO:0001824 62 62 0.000 1.000 1.000 1.000 1.000 0.801 ! blastocyst formation GO:0001825 26 26 0.000 1.000 1.000 1.000 1.000 0.722 ! release of cytochrome c from mitochondria GO:0001836 25 25 0.000 1.000 1.000 1.000 1.000 0.798 ! cell killing GO:0001906 34 34 0.000 1.000 1.000 1.000 1.000 0.660 ! regulation of leukocyte mediated cytotoxicity GO:0001910 33 33 0.000 1.000 1.000 1.000 1.000 0.856 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 26 26 0.000 1.000 1.000 1.000 1.000 0.838 ! negative regulation of endothelial cell proliferation GO:0001937 25 25 0.000 1.000 1.000 1.000 1.000 0.780 ! heart looping GO:0001947 44 44 0.000 1.000 1.000 1.000 1.000 0.870 ! endochondral ossification GO:0001958 22 22 0.000 1.000 1.000 1.000 1.000 0.708 GO:0036075|replacement ossification, ! response to amphetamine GO:0001975 26 26 0.000 1.000 1.000 1.000 1.000 0.845 ! columnar/cuboidal epithelial cell differentiation GO:0002065 20 20 0.000 1.000 1.000 1.000 1.000 0.756 ! lens development in camera-type eye GO:0002088 60 60 0.000 1.000 1.000 1.000 1.000 0.805 ! lens morphogenesis in camera-type eye GO:0002089 24 24 0.000 1.000 1.000 1.000 1.000 0.719 ! somatic diversification of immune receptors GO:0002200 39 39 0.000 1.000 1.000 1.000 1.000 0.843 ! myeloid cell activation involved in immune response GO:0002275 29 29 0.000 1.000 1.000 1.000 1.000 0.813 ! T cell activation involved in immune response GO:0002286 28 28 0.000 1.000 1.000 1.000 1.000 0.835 ! immunoglobulin production GO:0002377 46 46 0.000 1.000 1.000 1.000 1.000 0.848 ! immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 27 27 0.000 1.000 1.000 1.000 1.000 0.814 ! leukocyte mediated immunity GO:0002443 132 132 0.000 1.000 1.000 1.000 1.000 0.946 ! myeloid leukocyte mediated immunity GO:0002444 28 28 0.000 1.000 1.000 1.000 1.000 0.814 ! lymphocyte mediated immunity GO:0002449 105 105 0.000 1.000 1.000 1.000 1.000 0.946 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 47 47 0.000 1.000 1.000 1.000 1.000 0.647 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 34 34 0.000 1.000 1.000 1.000 1.000 0.850 GO:0016444|somatic cell DNA recombination, ! positive regulation of acute inflammatory response GO:0002675 22 22 0.000 1.000 1.000 1.000 1.000 0.841 ! positive regulation of immune effector process GO:0002699 100 100 0.000 1.000 1.000 1.000 1.000 0.892 ! positive regulation of production of molecular mediator of immune response GO:0002702 26 26 0.000 1.000 1.000 1.000 1.000 0.836 ! positive regulation of leukocyte mediated immunity GO:0002705 46 46 0.000 1.000 1.000 1.000 1.000 0.878 GO:0002708|positive regulation of lymphocyte mediated immunity, ! positive regulation of lymphocyte mediated immunity GO:0002708 46 46 0.000 1.000 1.000 1.000 1.000 0.878 GO:0002705|positive regulation of leukocyte mediated immunity, ! regulation of T cell mediated immunity GO:0002709 35 35 0.000 1.000 1.000 1.000 1.000 0.875 ! positive regulation of T cell mediated immunity GO:0002711 25 25 0.000 1.000 1.000 1.000 1.000 0.861 ! positive regulation of cytokine production involved in immune response GO:0002720 21 21 0.000 1.000 1.000 1.000 1.000 0.835 ! positive regulation of myeloid leukocyte differentiation GO:0002763 37 37 0.000 1.000 1.000 1.000 1.000 0.858 ! negative regulation of peptide secretion GO:0002792 30 30 0.000 1.000 1.000 1.000 1.000 0.814 ! positive regulation of adaptive immune response GO:0002821 49 49 0.000 1.000 1.000 1.000 1.000 0.887 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 46 46 0.000 1.000 1.000 1.000 1.000 0.885 ! regulation of T-helper 1 type immune response GO:0002825 20 20 0.000 1.000 1.000 1.000 1.000 0.817 ! regulation of inflammatory response to antigenic stimulus GO:0002861 21 21 0.000 1.000 1.000 1.000 1.000 0.834 ! regulation of myeloid leukocyte mediated immunity GO:0002886 23 23 0.000 1.000 1.000 1.000 1.000 0.817 ! regulation of humoral immune response GO:0002920 33 33 0.000 1.000 1.000 1.000 1.000 0.758 ! endocardial cushion development GO:0003197 25 25 0.000 1.000 1.000 1.000 1.000 0.841 ! axis elongation GO:0003401 25 25 0.000 1.000 1.000 1.000 1.000 0.837 ! neural retina development GO:0003407 34 34 0.000 1.000 1.000 1.000 1.000 0.770 ! glycerol metabolic process GO:0006071 25 25 0.000 1.000 1.000 1.000 1.000 0.568 ! pyruvate metabolic process GO:0006090 33 33 0.000 1.000 1.000 1.000 1.000 0.734 ! oxidative phosphorylation GO:0006119 62 62 0.000 1.000 1.000 1.000 1.000 0.690 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 38 38 0.000 1.000 1.000 1.000 1.000 0.304 ! purine base metabolic process GO:0006144 40 40 0.000 1.000 1.000 1.000 1.000 0.827 ! ATP catabolic process GO:0006200 71 71 0.000 1.000 1.000 1.000 1.000 0.839 ! pyrimidine base metabolic process GO:0006206 31 31 0.000 1.000 1.000 1.000 1.000 0.796 ! pyrimidine nucleoside metabolic process GO:0006213 51 51 0.000 1.000 1.000 1.000 1.000 0.857 ! pyrimidine nucleotide metabolic process GO:0006220 45 45 0.000 1.000 1.000 1.000 1.000 0.855 ! pyrimidine nucleotide biosynthetic process GO:0006221 31 31 0.000 1.000 1.000 1.000 1.000 0.833 ! DNA-dependent DNA replication GO:0006261 80 80 0.000 1.000 1.000 1.000 1.000 0.946 ! DNA-dependent DNA replication initiation GO:0006270 23 23 0.000 1.000 1.000 1.000 1.000 0.484 ! DNA strand elongation involved in DNA replication GO:0006271 34 34 0.000 1.000 1.000 1.000 1.000 0.666 ! regulation of DNA repair GO:0006282 49 49 0.000 1.000 1.000 1.000 1.000 0.815 ! transcription-coupled nucleotide-excision repair GO:0006283 47 47 0.000 1.000 1.000 1.000 1.000 0.743 ! base-excision repair GO:0006284 39 39 0.000 1.000 1.000 1.000 1.000 0.785 ! nucleotide-excision repair GO:0006289 80 80 0.000 1.000 1.000 1.000 1.000 0.946 ! nucleotide-excision repair, DNA gap filling GO:0006297 22 22 0.000 1.000 1.000 1.000 1.000 0.631 ! mismatch repair GO:0006298 20 20 0.000 1.000 1.000 1.000 1.000 0.728 ! double-strand break repair GO:0006302 98 98 0.000 1.000 1.000 1.000 1.000 0.946 ! DNA modification GO:0006304 66 66 0.000 1.000 1.000 1.000 1.000 0.857 ! DNA alkylation GO:0006305 35 35 0.000 1.000 1.000 1.000 1.000 0.761 GO:0006306|DNA methylation, ! DNA methylation GO:0006306 35 35 0.000 1.000 1.000 1.000 1.000 0.761 GO:0006305|DNA alkylation, ! DNA recombination GO:0006310 188 187 0.000 1.000 1.000 1.000 1.000 0.946 ! mitotic recombination GO:0006312 33 33 0.000 1.000 1.000 1.000 1.000 0.754 ! DNA packaging GO:0006323 151 150 0.000 1.000 1.000 1.000 1.000 0.577 ! chromatin assembly or disassembly GO:0006333 136 135 0.000 1.000 1.000 1.000 1.000 0.507 ! nucleosome assembly GO:0006334 107 107 0.000 1.000 1.000 1.000 1.000 0.140 ! DNA replication-independent nucleosome assembly GO:0006336 23 23 0.000 1.000 1.000 1.000 1.000 0.426 GO:0034724|DNA replication-independent nucleosome organization, GO:0034080|CenH3-containing nucleosome assembly at centromere, ! chromatin silencing GO:0006342 21 21 0.000 1.000 1.000 1.000 1.000 0.707 ! transcription termination, DNA-dependent GO:0006353 83 83 0.000 1.000 1.000 1.000 1.000 0.666 ! transcription elongation, DNA-dependent GO:0006354 89 85 0.000 1.000 1.000 1.000 1.000 0.695 ! transcription from RNA polymerase I promoter GO:0006360 25 25 0.000 1.000 1.000 1.000 1.000 0.575 ! transcription initiation from RNA polymerase I promoter GO:0006361 24 24 0.000 1.000 1.000 1.000 1.000 0.570 ! termination of RNA polymerase I transcription GO:0006363 21 21 0.000 1.000 1.000 1.000 1.000 0.497 ! rRNA processing GO:0006364 104 104 0.000 1.000 1.000 1.000 1.000 0.540 ! transcription elongation from RNA polymerase II promoter GO:0006368 69 65 0.000 1.000 1.000 1.000 1.000 0.648 ! termination of RNA polymerase II transcription GO:0006369 46 46 0.000 1.000 1.000 1.000 1.000 0.394 ! mRNA capping GO:0006370 30 30 0.000 1.000 1.000 1.000 1.000 0.617 ! mRNA polyadenylation GO:0006378 24 24 0.000 1.000 1.000 1.000 1.000 0.536 ! transcription from RNA polymerase III promoter GO:0006383 40 40 0.000 1.000 1.000 1.000 1.000 0.237 ! tRNA metabolic process GO:0006399 124 124 0.000 1.000 1.000 1.000 1.000 0.764 ! tRNA modification GO:0006400 20 20 0.000 1.000 1.000 1.000 1.000 0.527 ! RNA localization GO:0006403 137 137 0.000 1.000 1.000 1.000 1.000 0.777 ! RNA export from nucleus GO:0006405 70 70 0.000 1.000 1.000 1.000 1.000 0.627 ! mRNA export from nucleus GO:0006406 63 63 0.000 1.000 1.000 1.000 1.000 0.603 ! tRNA aminoacylation for protein translation GO:0006418 48 48 0.000 1.000 1.000 1.000 1.000 0.782 ! regulation of translational initiation GO:0006446 53 52 0.000 1.000 1.000 1.000 1.000 0.638 ! protein acetylation GO:0006473 105 105 0.000 1.000 1.000 1.000 1.000 0.946 ! internal protein amino acid acetylation GO:0006475 92 92 0.000 1.000 1.000 1.000 1.000 0.946 ! protein O-linked glycosylation GO:0006493 74 73 0.000 1.000 1.000 1.000 1.000 0.352 ! C-terminal protein lipidation GO:0006501 25 25 0.000 1.000 1.000 1.000 1.000 0.430 ! GPI anchor metabolic process GO:0006505 36 36 0.000 1.000 1.000 1.000 1.000 0.444 ! GPI anchor biosynthetic process GO:0006506 34 34 0.000 1.000 1.000 1.000 1.000 0.421 ! protein monoubiquitination GO:0006513 37 37 0.000 1.000 1.000 1.000 1.000 0.682 ! regulation of cellular amino acid metabolic process GO:0006521 58 58 0.000 1.000 1.000 1.000 1.000 0.810 ! indolalkylamine metabolic process GO:0006586 22 22 0.000 1.000 1.000 1.000 1.000 0.767 GO:0042430|indole-containing compound metabolic process, ! polyamine metabolic process GO:0006595 20 20 0.000 1.000 1.000 1.000 1.000 0.671 ! protein export from nucleus GO:0006611 25 25 0.000 1.000 1.000 1.000 1.000 0.489 ! protein targeting to mitochondrion GO:0006626 55 54 0.000 1.000 1.000 1.000 1.000 0.651 ! fatty acid beta-oxidation GO:0006635 44 44 0.000 1.000 1.000 1.000 1.000 0.806 ! acyl-CoA metabolic process GO:0006637 40 40 0.000 1.000 1.000 1.000 1.000 0.802 GO:0035383|thioester metabolic process, ! neutral lipid metabolic process GO:0006638 96 96 0.000 1.000 1.000 1.000 1.000 0.946 ! acylglycerol metabolic process GO:0006639 95 95 0.000 1.000 1.000 1.000 1.000 0.946 ! triglyceride metabolic process GO:0006641 87 87 0.000 1.000 1.000 1.000 1.000 0.879 ! membrane lipid metabolic process GO:0006643 125 125 0.000 1.000 1.000 1.000 1.000 0.946 ! phosphatidic acid biosynthetic process GO:0006654 31 31 0.000 1.000 1.000 1.000 1.000 0.661 GO:0046473|phosphatidic acid metabolic process, ! phosphatidylcholine biosynthetic process GO:0006656 25 25 0.000 1.000 1.000 1.000 1.000 0.603 ! glycerol ether metabolic process GO:0006662 117 117 0.000 1.000 1.000 1.000 1.000 0.946 ! glycolipid metabolic process GO:0006664 64 64 0.000 1.000 1.000 1.000 1.000 0.724 ! sphingolipid metabolic process GO:0006665 118 118 0.000 1.000 1.000 1.000 1.000 0.946 ! ceramide metabolic process GO:0006672 60 60 0.000 1.000 1.000 1.000 1.000 0.808 ! glycosphingolipid metabolic process GO:0006687 58 58 0.000 1.000 1.000 1.000 1.000 0.720 ! leukotriene metabolic process GO:0006691 34 34 0.000 1.000 1.000 1.000 1.000 0.727 ! cholesterol biosynthetic process GO:0006695 34 34 0.000 1.000 1.000 1.000 1.000 0.682 ! bile acid biosynthetic process GO:0006699 22 22 0.000 1.000 1.000 1.000 1.000 0.642 ! steroid catabolic process GO:0006706 23 23 0.000 1.000 1.000 1.000 1.000 0.682 ! isoprenoid metabolic process GO:0006720 79 79 0.000 1.000 1.000 1.000 1.000 0.869 ! terpenoid metabolic process GO:0006721 57 57 0.000 1.000 1.000 1.000 1.000 0.840 ! oxidoreduction coenzyme metabolic process GO:0006733 59 59 0.000 1.000 1.000 1.000 1.000 0.841 ! NADP metabolic process GO:0006739 27 27 0.000 1.000 1.000 1.000 1.000 0.745 ! glutathione metabolic process GO:0006749 50 50 0.000 1.000 1.000 1.000 1.000 0.718 ! vitamin A metabolic process GO:0006776 38 38 0.000 1.000 1.000 1.000 1.000 0.771 ! porphyrin-containing compound metabolic process GO:0006778 47 47 0.000 1.000 1.000 1.000 1.000 0.799 ! porphyrin-containing compound biosynthetic process GO:0006779 31 31 0.000 1.000 1.000 1.000 1.000 0.708 GO:0033014|tetrapyrrole biosynthetic process, ! heme biosynthetic process GO:0006783 22 22 0.000 1.000 1.000 1.000 1.000 0.620 ! potassium ion transport GO:0006813 92 92 0.000 1.000 1.000 1.000 1.000 0.684 ! sodium ion transport GO:0006814 78 78 0.000 1.000 1.000 1.000 1.000 0.628 ! hydrogen transport GO:0006818 59 58 0.000 1.000 1.000 1.000 1.000 0.786 ! chloride transport GO:0006821 26 26 0.000 1.000 1.000 1.000 1.000 0.429 ! iron ion transport GO:0006826 50 50 0.000 1.000 1.000 1.000 1.000 0.709 ! zinc ion transport GO:0006829 22 22 0.000 1.000 1.000 1.000 1.000 0.128 ! water transport GO:0006833 40 40 0.000 1.000 1.000 1.000 1.000 0.781 ! cellular iron ion homeostasis GO:0006879 68 68 0.000 1.000 1.000 1.000 1.000 0.798 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 24 0.000 1.000 1.000 1.000 1.000 0.444 ! intra-Golgi vesicle-mediated transport GO:0006891 31 31 0.000 1.000 1.000 1.000 1.000 0.181 ! post-Golgi vesicle-mediated transport GO:0006892 74 74 0.000 1.000 1.000 1.000 1.000 0.680 ! Golgi to plasma membrane transport GO:0006893 25 25 0.000 1.000 1.000 1.000 1.000 0.537 ! vesicle docking involved in exocytosis GO:0006904 25 25 0.000 1.000 1.000 1.000 1.000 0.519 ! vesicle fusion GO:0006906 26 25 0.000 1.000 1.000 1.000 1.000 0.579 ! autophagy GO:0006914 92 89 0.000 1.000 1.000 1.000 1.000 0.593 ! cellular membrane fusion GO:0006944 77 75 0.000 1.000 1.000 1.000 1.000 0.713 ! complement activation GO:0006956 51 51 0.000 1.000 1.000 1.000 1.000 0.525 ! complement activation, classical pathway GO:0006958 39 39 0.000 1.000 1.000 1.000 1.000 0.491 ! humoral immune response GO:0006959 102 102 0.000 1.000 1.000 1.000 1.000 0.780 ! cellular defense response GO:0006968 60 60 0.000 1.000 1.000 1.000 1.000 0.388 ! response to osmotic stress GO:0006970 51 51 0.000 1.000 1.000 1.000 1.000 0.847 ! activation of signaling protein activity involved in unfolded protein response GO:0006987 64 64 0.000 1.000 1.000 1.000 1.000 0.711 ! microtubule-based movement GO:0007018 168 168 0.000 1.000 1.000 1.000 1.000 0.783 ! endoplasmic reticulum organization GO:0007029 22 22 0.000 1.000 1.000 1.000 1.000 0.593 ! Golgi organization GO:0007030 40 40 0.000 1.000 1.000 1.000 1.000 0.558 ! peroxisome organization GO:0007031 33 33 0.000 1.000 1.000 1.000 1.000 0.724 ! endosome organization GO:0007032 25 25 0.000 1.000 1.000 1.000 1.000 0.413 ! vacuolar transport GO:0007034 44 44 0.000 1.000 1.000 1.000 1.000 0.631 ! lysosomal transport GO:0007041 39 39 0.000 1.000 1.000 1.000 1.000 0.628 ! spindle organization GO:0007051 78 76 0.000 1.000 1.000 1.000 1.000 0.744 ! mitotic spindle organization GO:0007052 31 31 0.000 1.000 1.000 1.000 1.000 0.697 ! chromosome segregation GO:0007059 141 137 0.000 1.000 1.000 1.000 1.000 0.946 ! sister chromatid cohesion GO:0007062 26 26 0.000 1.000 1.000 1.000 1.000 0.662 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 30 30 0.000 1.000 1.000 1.000 1.000 0.709 ! centrosome cycle GO:0007098 29 29 0.000 1.000 1.000 1.000 1.000 0.604 ! meiosis GO:0007126 148 145 0.000 1.000 1.000 1.000 1.000 0.946 GO:0051327|M phase of meiotic cell cycle, ! meiosis I GO:0007127 79 79 0.000 1.000 1.000 1.000 1.000 0.837 ! meiotic prophase I GO:0007128 22 22 0.000 1.000 1.000 1.000 1.000 0.536 ! synapsis GO:0007129 24 24 0.000 1.000 1.000 1.000 1.000 0.652 ! reciprocal meiotic recombination GO:0007131 36 36 0.000 1.000 1.000 1.000 1.000 0.755 GO:0035825|reciprocal DNA recombination, ! male meiosis GO:0007140 38 35 0.000 1.000 1.000 1.000 1.000 0.600 ! leukocyte cell-cell adhesion GO:0007159 39 39 0.000 1.000 1.000 1.000 1.000 0.812 ! establishment or maintenance of cell polarity GO:0007163 103 102 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of epidermal growth factor-activated receptor activity GO:0007176 23 23 0.000 1.000 1.000 1.000 1.000 0.719 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 45 0.000 1.000 1.000 1.000 1.000 0.835 ! activation of adenylate cyclase activity GO:0007190 62 62 0.000 1.000 1.000 1.000 1.000 0.858 ! inhibition of adenylate cyclase activity by G-protein signaling pathway GO:0007193 43 43 0.000 1.000 1.000 1.000 1.000 0.806 ! negative regulation of adenylate cyclase activity GO:0007194 56 56 0.000 1.000 1.000 1.000 1.000 0.835 ! dopamine receptor signaling pathway GO:0007212 26 25 0.000 1.000 1.000 1.000 1.000 0.706 ! glutamate receptor signaling pathway GO:0007215 26 26 0.000 1.000 1.000 1.000 1.000 0.746 ! neuropeptide signaling pathway GO:0007218 91 90 0.000 1.000 1.000 1.000 1.000 0.0572 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 50 50 0.000 1.000 1.000 1.000 1.000 0.721 ! JNK cascade GO:0007254 85 85 0.000 1.000 1.000 1.000 1.000 0.946 ! activation of JUN kinase activity GO:0007257 35 35 0.000 1.000 1.000 1.000 1.000 0.721 ! neuron-neuron synaptic transmission GO:0007270 42 42 0.000 1.000 1.000 1.000 1.000 0.824 ! single fertilization GO:0007338 76 75 0.000 1.000 1.000 1.000 1.000 0.600 ! determination of left/right symmetry GO:0007368 83 83 0.000 1.000 1.000 1.000 1.000 0.880 ! ectoderm development GO:0007398 22 21 0.000 1.000 1.000 1.000 1.000 0.479 ! neuroblast proliferation GO:0007405 22 22 0.000 1.000 1.000 1.000 1.000 0.763 ! synapse assembly GO:0007416 47 47 0.000 1.000 1.000 1.000 1.000 0.689 ! endoderm development GO:0007492 56 56 0.000 1.000 1.000 1.000 1.000 0.868 ! digestion GO:0007586 100 100 0.000 1.000 1.000 1.000 1.000 0.794 ! excretion GO:0007588 50 50 0.000 1.000 1.000 1.000 1.000 0.755 ! sensory perception of sound GO:0007605 127 127 0.000 1.000 1.000 1.000 1.000 0.946 ! sensory perception of chemical stimulus GO:0007606 116 116 0.000 1.000 1.000 1.000 1.000 0.210 ! sensory perception of smell GO:0007608 60 60 0.000 1.000 1.000 1.000 1.000 0.0200 ! long-term memory GO:0007616 22 22 0.000 1.000 1.000 1.000 1.000 0.750 ! mating GO:0007618 31 31 0.000 1.000 1.000 1.000 1.000 0.778 ! adult walking behavior GO:0007628 31 31 0.000 1.000 1.000 1.000 1.000 0.823 ! feeding behavior GO:0007631 78 78 0.000 1.000 1.000 1.000 1.000 0.865 ! tRNA processing GO:0008033 76 76 0.000 1.000 1.000 1.000 1.000 0.408 ! cell recognition GO:0008037 75 75 0.000 1.000 1.000 1.000 1.000 0.831 ! neuron recognition GO:0008038 30 30 0.000 1.000 1.000 1.000 1.000 0.657 ! regulation of actin polymerization or depolymerization GO:0008064 101 100 0.000 1.000 1.000 1.000 1.000 0.946 ! axon cargo transport GO:0008088 37 37 0.000 1.000 1.000 1.000 1.000 0.762 ! anterograde axon cargo transport GO:0008089 23 23 0.000 1.000 1.000 1.000 1.000 0.589 ! negative regulation of DNA replication GO:0008156 38 38 0.000 1.000 1.000 1.000 1.000 0.751 ! bile acid metabolic process GO:0008206 40 40 0.000 1.000 1.000 1.000 1.000 0.720 ! estrogen metabolic process GO:0008210 20 20 0.000 1.000 1.000 1.000 1.000 0.638 ! isoprenoid biosynthetic process GO:0008299 23 23 0.000 1.000 1.000 1.000 1.000 0.732 ! endosome to lysosome transport GO:0008333 27 27 0.000 1.000 1.000 1.000 1.000 0.440 ! histone mRNA metabolic process GO:0008334 29 29 0.000 1.000 1.000 1.000 1.000 0.571 ! fatty acid catabolic process GO:0009062 56 56 0.000 1.000 1.000 1.000 1.000 0.830 ! serine family amino acid metabolic process GO:0009069 32 32 0.000 1.000 1.000 1.000 1.000 0.791 ! aromatic amino acid family metabolic process GO:0009072 28 28 0.000 1.000 1.000 1.000 1.000 0.780 ! branched chain family amino acid metabolic process GO:0009081 23 23 0.000 1.000 1.000 1.000 1.000 0.701 ! nucleobase metabolic process GO:0009112 66 66 0.000 1.000 1.000 1.000 1.000 0.871 ! nucleoside metabolic process GO:0009116 102 101 0.000 1.000 1.000 1.000 1.000 0.946 ! ribonucleoside metabolic process GO:0009119 78 78 0.000 1.000 1.000 1.000 1.000 0.883 ! nucleoside monophosphate catabolic process GO:0009125 24 23 0.000 1.000 1.000 1.000 1.000 0.703 ! purine nucleoside monophosphate biosynthetic process GO:0009127 22 22 0.000 1.000 1.000 1.000 1.000 0.767 GO:0009168|purine ribonucleoside monophosphate biosynthetic process, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 24 24 0.000 1.000 1.000 1.000 1.000 0.774 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 20 20 0.000 1.000 1.000 1.000 1.000 0.744 ! ribonucleoside monophosphate biosynthetic process GO:0009156 36 36 0.000 1.000 1.000 1.000 1.000 0.845 ! nucleoside biosynthetic process GO:0009163 32 32 0.000 1.000 1.000 1.000 1.000 0.852 ! nucleoside catabolic process GO:0009164 29 29 0.000 1.000 1.000 1.000 1.000 0.825 ! purine ribonucleoside monophosphate biosynthetic process GO:0009168 22 22 0.000 1.000 1.000 1.000 1.000 0.767 GO:0009127|purine nucleoside monophosphate biosynthetic process, ! pyrimidine ribonucleotide metabolic process GO:0009218 27 27 0.000 1.000 1.000 1.000 1.000 0.806 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 25 25 0.000 1.000 1.000 1.000 1.000 0.793 ! deoxyribonucleotide metabolic process GO:0009262 35 34 0.000 1.000 1.000 1.000 1.000 0.843 ! 2'-deoxyribonucleotide metabolic process GO:0009394 28 28 0.000 1.000 1.000 1.000 1.000 0.832 ! response to heat GO:0009408 60 60 0.000 1.000 1.000 1.000 1.000 0.799 ! RNA modification GO:0009451 58 58 0.000 1.000 1.000 1.000 1.000 0.690 ! RNA capping GO:0009452 31 31 0.000 1.000 1.000 1.000 1.000 0.622 ! fertilization GO:0009566 104 103 0.000 1.000 1.000 1.000 1.000 0.740 ! detection of chemical stimulus GO:0009593 90 90 0.000 1.000 1.000 1.000 1.000 0.586 ! response to fungus GO:0009620 31 31 0.000 1.000 1.000 1.000 1.000 0.632 ! response to toxin GO:0009636 98 98 0.000 1.000 1.000 1.000 1.000 0.946 ! response to salt stress GO:0009651 21 21 0.000 1.000 1.000 1.000 1.000 0.824 ! specification of symmetry GO:0009799 90 90 0.000 1.000 1.000 1.000 1.000 0.885 ! determination of bilateral symmetry GO:0009855 89 89 0.000 1.000 1.000 1.000 1.000 0.884 ! proximal/distal pattern formation GO:0009954 32 32 0.000 1.000 1.000 1.000 1.000 0.747 ! cell-cell recognition GO:0009988 26 26 0.000 1.000 1.000 1.000 1.000 0.628 ! response to zinc ion GO:0010043 33 33 0.000 1.000 1.000 1.000 1.000 0.693 ! response to X-ray GO:0010165 21 21 0.000 1.000 1.000 1.000 1.000 0.708 ! response to ionizing radiation GO:0010212 107 106 0.000 1.000 1.000 1.000 1.000 0.946 ! response to gamma radiation GO:0010332 36 36 0.000 1.000 1.000 1.000 1.000 0.828 ! regulation of G2/M transition of mitotic cell cycle GO:0010389 32 32 0.000 1.000 1.000 1.000 1.000 0.723 ! proteasomal protein catabolic process GO:0010498 184 184 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of autophagy GO:0010506 58 58 0.000 1.000 1.000 1.000 1.000 0.763 ! positive regulation of autophagy GO:0010508 23 23 0.000 1.000 1.000 1.000 1.000 0.590 ! regulation of calcium ion transport into cytosol GO:0010522 54 54 0.000 1.000 1.000 1.000 1.000 0.881 ! positive regulation of calcium ion transport into cytosol GO:0010524 27 27 0.000 1.000 1.000 1.000 1.000 0.827 ! regulation of vascular endothelial growth factor production GO:0010574 23 23 0.000 1.000 1.000 1.000 1.000 0.836 ! regulation of adenylate cyclase activity involved in G-protein signaling pathway GO:0010578 47 47 0.000 1.000 1.000 1.000 1.000 0.840 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, ! positive regulation of adenylate cyclase activity by G-protein signaling pathway GO:0010579 47 47 0.000 1.000 1.000 1.000 1.000 0.840 GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling pathway, ! negative regulation of endothelial cell migration GO:0010596 26 26 0.000 1.000 1.000 1.000 1.000 0.789 ! regulation of epithelial cell migration GO:0010632 22 22 0.000 1.000 1.000 1.000 1.000 0.810 ! regulation of collagen metabolic process GO:0010712 24 24 0.000 1.000 1.000 1.000 1.000 0.836 ! positive regulation of collagen metabolic process GO:0010714 20 20 0.000 1.000 1.000 1.000 1.000 0.814 GO:0032967|positive regulation of collagen biosynthetic process, ! regulation of epithelial to mesenchymal transition GO:0010717 41 41 0.000 1.000 1.000 1.000 1.000 0.869 ! positive regulation of epithelial to mesenchymal transition GO:0010718 23 23 0.000 1.000 1.000 1.000 1.000 0.816 ! positive regulation of cell morphogenesis involved in differentiation GO:0010770 32 32 0.000 1.000 1.000 1.000 1.000 0.853 ! negative regulation of cell morphogenesis involved in differentiation GO:0010771 21 21 0.000 1.000 1.000 1.000 1.000 0.803 ! telomere maintenance via telomere lengthening GO:0010833 35 35 0.000 1.000 1.000 1.000 1.000 0.783 ! negative regulation of phosphatase activity GO:0010923 64 64 0.000 1.000 1.000 1.000 1.000 0.242 ! microtubule-based transport GO:0010970 68 68 0.000 1.000 1.000 1.000 1.000 0.828 ! oligodendrocyte development GO:0014003 34 32 0.000 1.000 1.000 1.000 1.000 0.820 ! response to isoquinoline alkaloid GO:0014072 22 22 0.000 1.000 1.000 1.000 1.000 0.783 ! response to tropane GO:0014073 31 31 0.000 1.000 1.000 1.000 1.000 0.858 GO:0042220|response to cocaine, ! response to activity GO:0014823 32 32 0.000 1.000 1.000 1.000 1.000 0.823 ! myotube differentiation GO:0014902 28 28 0.000 1.000 1.000 1.000 1.000 0.782 ! ferric iron transport GO:0015682 30 30 0.000 1.000 1.000 1.000 1.000 0.592 GO:0033572|transferrin transport, ! organic cation transport GO:0015695 28 28 0.000 1.000 1.000 1.000 1.000 0.701 ! bicarbonate transport GO:0015701 29 29 0.000 1.000 1.000 1.000 1.000 0.396 ! organic anion transport GO:0015711 72 72 0.000 1.000 1.000 1.000 1.000 0.751 ! bile acid and bile salt transport GO:0015721 22 20 0.000 1.000 1.000 1.000 1.000 0.490 ! monoamine transport GO:0015844 21 21 0.000 1.000 1.000 1.000 1.000 0.784 ! organic alcohol transport GO:0015850 21 21 0.000 1.000 1.000 1.000 1.000 0.760 ! nucleobase-containing compound transport GO:0015931 151 151 0.000 1.000 1.000 1.000 1.000 0.946 ! energy coupled proton transport, against electrochemical gradient GO:0015988 30 30 0.000 1.000 1.000 1.000 1.000 0.665 GO:0015991|ATP hydrolysis coupled proton transport, ! ATP hydrolysis coupled proton transport GO:0015991 30 30 0.000 1.000 1.000 1.000 1.000 0.665 GO:0015988|energy coupled proton transport, against electrochemical gradient, ! proton transport GO:0015992 57 56 0.000 1.000 1.000 1.000 1.000 0.777 ! immunoglobulin mediated immune response GO:0016064 79 79 0.000 1.000 1.000 1.000 1.000 0.841 ! rRNA metabolic process GO:0016072 110 110 0.000 1.000 1.000 1.000 1.000 0.571 ! synaptic vesicle exocytosis GO:0016079 29 29 0.000 1.000 1.000 1.000 1.000 0.672 ! diterpenoid metabolic process GO:0016101 46 46 0.000 1.000 1.000 1.000 1.000 0.802 ! sterol biosynthetic process GO:0016126 40 40 0.000 1.000 1.000 1.000 1.000 0.674 ! macroautophagy GO:0016236 31 30 0.000 1.000 1.000 1.000 1.000 0.515 ! O-glycan processing GO:0016266 57 56 0.000 1.000 1.000 1.000 1.000 0.0881 ! calcium-independent cell-cell adhesion GO:0016338 22 22 0.000 1.000 1.000 1.000 1.000 0.00164 ! posttranscriptional gene silencing GO:0016441 33 29 0.000 1.000 1.000 1.000 1.000 0.773 GO:0035194|posttranscriptional gene silencing by RNA, ! somatic cell DNA recombination GO:0016444 34 34 0.000 1.000 1.000 1.000 1.000 0.850 GO:0002562|somatic diversification of immune receptors via germline recombination within a single locus, ! somatic diversification of immunoglobulins GO:0016445 30 30 0.000 1.000 1.000 1.000 1.000 0.809 ! somatic recombination of immunoglobulin gene segments GO:0016447 24 24 0.000 1.000 1.000 1.000 1.000 0.812 ! gene silencing GO:0016458 77 73 0.000 1.000 1.000 1.000 1.000 0.854 ! histone acetylation GO:0016573 84 84 0.000 1.000 1.000 1.000 1.000 0.946 ! histone ubiquitination GO:0016574 29 29 0.000 1.000 1.000 1.000 1.000 0.699 ! histone deacetylation GO:0016575 24 24 0.000 1.000 1.000 1.000 1.000 0.707 ! protein sumoylation GO:0016925 23 23 0.000 1.000 1.000 1.000 1.000 0.572 ! stem cell division GO:0017145 24 24 0.000 1.000 1.000 1.000 1.000 0.809 ! negative regulation of translation GO:0017148 67 63 0.000 1.000 1.000 1.000 1.000 0.795 ! calcium ion-dependent exocytosis GO:0017156 28 27 0.000 1.000 1.000 1.000 1.000 0.584 ! regulation of exocytosis GO:0017157 80 80 0.000 1.000 1.000 1.000 1.000 0.848 ! regulation of calcium ion-dependent exocytosis GO:0017158 25 25 0.000 1.000 1.000 1.000 1.000 0.683 ! internal peptidyl-lysine acetylation GO:0018393 86 86 0.000 1.000 1.000 1.000 1.000 0.946 ! peptidyl-lysine acetylation GO:0018394 88 88 0.000 1.000 1.000 1.000 1.000 0.946 ! C-terminal protein amino acid modification GO:0018410 30 30 0.000 1.000 1.000 1.000 1.000 0.558 ! organic ether metabolic process GO:0018904 122 122 0.000 1.000 1.000 1.000 1.000 0.946 ! reproductive behavior GO:0019098 21 21 0.000 1.000 1.000 1.000 1.000 0.770 ! pyridine nucleotide metabolic process GO:0019362 48 48 0.000 1.000 1.000 1.000 1.000 0.834 GO:0046496|nicotinamide nucleotide metabolic process, ! leukotriene biosynthetic process GO:0019370 28 28 0.000 1.000 1.000 1.000 1.000 0.645 GO:0043450|alkene biosynthetic process, ! alditol metabolic process GO:0019400 26 26 0.000 1.000 1.000 1.000 1.000 0.575 ! triglyceride biosynthetic process GO:0019432 43 43 0.000 1.000 1.000 1.000 1.000 0.815 ! aromatic compound catabolic process GO:0019439 29 29 0.000 1.000 1.000 1.000 1.000 0.778 ! NAD metabolic process GO:0019674 24 24 0.000 1.000 1.000 1.000 1.000 0.751 ! B cell mediated immunity GO:0019724 81 81 0.000 1.000 1.000 1.000 1.000 0.946 ! polyol metabolic process GO:0019751 37 37 0.000 1.000 1.000 1.000 1.000 0.690 ! cytolysis GO:0019835 21 21 0.000 1.000 1.000 1.000 1.000 0.541 ! dorsal spinal cord development GO:0021516 21 20 0.000 1.000 1.000 1.000 1.000 0.560 ! pallium development GO:0021543 97 96 0.000 1.000 1.000 1.000 1.000 0.887 ! cerebellum development GO:0021549 67 66 0.000 1.000 1.000 1.000 1.000 0.862 ! cerebellum morphogenesis GO:0021587 29 29 0.000 1.000 1.000 1.000 1.000 0.819 ! cranial nerve morphogenesis GO:0021602 21 21 0.000 1.000 1.000 1.000 1.000 0.809 ! cerebellar cortex development GO:0021695 35 35 0.000 1.000 1.000 1.000 1.000 0.817 ! cerebellar cortex morphogenesis GO:0021696 22 22 0.000 1.000 1.000 1.000 1.000 0.763 ! limbic system development GO:0021761 73 72 0.000 1.000 1.000 1.000 1.000 0.875 ! hippocampus development GO:0021766 51 50 0.000 1.000 1.000 1.000 1.000 0.849 ! olfactory bulb development GO:0021772 29 29 0.000 1.000 1.000 1.000 1.000 0.823 ! cerebral cortex cell migration GO:0021795 28 28 0.000 1.000 1.000 1.000 1.000 0.856 ! cell proliferation in forebrain GO:0021846 25 25 0.000 1.000 1.000 1.000 1.000 0.751 ! forebrain regionalization GO:0021871 20 20 0.000 1.000 1.000 1.000 1.000 0.727 ! forebrain neuron differentiation GO:0021879 27 27 0.000 1.000 1.000 1.000 1.000 0.819 ! cerebral cortex development GO:0021987 65 64 0.000 1.000 1.000 1.000 1.000 0.876 ! olfactory lobe development GO:0021988 30 30 0.000 1.000 1.000 1.000 1.000 0.829 ! telencephalon cell migration GO:0022029 38 38 0.000 1.000 1.000 1.000 1.000 0.878 ! metencephalon development GO:0022037 77 76 0.000 1.000 1.000 1.000 1.000 0.874 ! membrane docking GO:0022406 34 34 0.000 1.000 1.000 1.000 1.000 0.654 ! negative regulation of cell-cell adhesion GO:0022408 28 28 0.000 1.000 1.000 1.000 1.000 0.833 ! cellular process involved in reproduction in multicellular organism GO:0022412 25 24 0.000 1.000 1.000 1.000 1.000 0.585 ! digestive system process GO:0022600 37 37 0.000 1.000 1.000 1.000 1.000 0.790 ! DNA strand elongation GO:0022616 36 36 0.000 1.000 1.000 1.000 1.000 0.691 ! ribonucleoprotein complex assembly GO:0022618 102 102 0.000 1.000 1.000 1.000 1.000 0.787 ! respiratory electron transport chain GO:0022904 101 101 0.000 1.000 1.000 1.000 1.000 0.754 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 31 0.000 1.000 1.000 1.000 1.000 0.771 ! establishment of cell polarity GO:0030010 62 61 0.000 1.000 1.000 1.000 1.000 0.838 ! regulation of mitotic metaphase/anaphase transition GO:0030071 40 40 0.000 1.000 1.000 1.000 1.000 0.796 ! insulin secretion GO:0030073 30 30 0.000 1.000 1.000 1.000 1.000 0.725 ! water homeostasis GO:0030104 23 23 0.000 1.000 1.000 1.000 1.000 0.830 ! sphingolipid biosynthetic process GO:0030148 58 58 0.000 1.000 1.000 1.000 1.000 0.752 ! sphingolipid catabolic process GO:0030149 20 20 0.000 1.000 1.000 1.000 1.000 0.725 ! hyaluronan metabolic process GO:0030212 25 25 0.000 1.000 1.000 1.000 1.000 0.552 ! chromosome condensation GO:0030261 29 29 0.000 1.000 1.000 1.000 1.000 0.512 ! positive regulation of cell growth GO:0030307 90 89 0.000 1.000 1.000 1.000 1.000 0.879 ! osteoclast differentiation GO:0030316 20 20 0.000 1.000 1.000 1.000 1.000 0.700 ! sperm motility GO:0030317 32 32 0.000 1.000 1.000 1.000 1.000 0.471 ! melanocyte differentiation GO:0030318 29 29 0.000 1.000 1.000 1.000 1.000 0.764 ! ER-associated protein catabolic process GO:0030433 36 36 0.000 1.000 1.000 1.000 1.000 0.368 ! regulation of complement activation GO:0030449 20 20 0.000 1.000 1.000 1.000 1.000 0.524 GO:2000257|regulation of protein activation cascade, ! positive regulation of bone mineralization GO:0030501 30 30 0.000 1.000 1.000 1.000 1.000 0.852 ! regulation of axon extension GO:0030516 38 38 0.000 1.000 1.000 1.000 1.000 0.804 ! male genitalia development GO:0030539 22 22 0.000 1.000 1.000 1.000 1.000 0.748 ! regulation of cellular pH GO:0030641 25 25 0.000 1.000 1.000 1.000 1.000 0.728 ! cytoskeleton-dependent intracellular transport GO:0030705 73 73 0.000 1.000 1.000 1.000 1.000 0.825 ! regulation of actin filament length GO:0030832 102 101 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of actin filament polymerization GO:0030833 89 88 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of actin filament depolymerization GO:0030834 32 32 0.000 1.000 1.000 1.000 1.000 0.679 ! negative regulation of actin filament depolymerization GO:0030835 27 27 0.000 1.000 1.000 1.000 1.000 0.605 ! negative regulation of actin filament polymerization GO:0030837 35 35 0.000 1.000 1.000 1.000 1.000 0.661 ! positive regulation of actin filament polymerization GO:0030838 41 40 0.000 1.000 1.000 1.000 1.000 0.778 ! prostate gland development GO:0030850 39 39 0.000 1.000 1.000 1.000 1.000 0.839 ! positive regulation of epithelial cell differentiation GO:0030858 29 29 0.000 1.000 1.000 1.000 1.000 0.838 ! thyroid gland development GO:0030878 20 20 0.000 1.000 1.000 1.000 1.000 0.780 ! microtubule organizing center organization GO:0031023 55 55 0.000 1.000 1.000 1.000 1.000 0.699 ! gene silencing by RNA GO:0031047 50 46 0.000 1.000 1.000 1.000 1.000 0.785 ! chromatin remodeling at centromere GO:0031055 25 25 0.000 1.000 1.000 1.000 1.000 0.490 ! positive regulation of histone modification GO:0031058 34 34 0.000 1.000 1.000 1.000 1.000 0.849 ! hair follicle morphogenesis GO:0031069 27 27 0.000 1.000 1.000 1.000 1.000 0.776 ! regulation of microtubule polymerization or depolymerization GO:0031110 42 41 0.000 1.000 1.000 1.000 1.000 0.765 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 24 24 0.000 1.000 1.000 1.000 1.000 0.698 ! RNA 3'-end processing GO:0031123 94 92 0.000 1.000 1.000 1.000 1.000 0.745 ! mRNA 3'-end processing GO:0031124 79 78 0.000 1.000 1.000 1.000 1.000 0.674 ! developmental induction GO:0031128 33 33 0.000 1.000 1.000 1.000 1.000 0.853 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 80 80 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of cyclase activity GO:0031279 111 111 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of cyclase activity GO:0031280 57 57 0.000 1.000 1.000 1.000 1.000 0.837 ! positive regulation of cyclase activity GO:0031281 68 68 0.000 1.000 1.000 1.000 1.000 0.866 ! regulation of cell killing GO:0031341 36 36 0.000 1.000 1.000 1.000 1.000 0.864 ! positive regulation of cell killing GO:0031343 29 29 0.000 1.000 1.000 1.000 1.000 0.850 ! keratinization GO:0031424 44 44 0.000 1.000 1.000 1.000 1.000 0.000936 ! chromatin assembly GO:0031497 118 117 0.000 1.000 1.000 1.000 1.000 0.330 ! G2/M transition DNA damage checkpoint GO:0031572 32 32 0.000 1.000 1.000 1.000 1.000 0.675 ! G2/M transition checkpoint GO:0031576 41 41 0.000 1.000 1.000 1.000 1.000 0.738 ! spindle checkpoint GO:0031577 36 36 0.000 1.000 1.000 1.000 1.000 0.730 ! negative regulation of neurological system process GO:0031645 39 39 0.000 1.000 1.000 1.000 1.000 0.855 ! positive regulation of neurological system process GO:0031646 64 62 0.000 1.000 1.000 1.000 1.000 0.883 ! lipopolysaccharide-mediated signaling pathway GO:0031663 26 26 0.000 1.000 1.000 1.000 1.000 0.843 ! regulation of ARF protein signal transduction GO:0032012 48 48 0.000 1.000 1.000 1.000 1.000 0.00639 ! regulation of nuclease activity GO:0032069 72 72 0.000 1.000 1.000 1.000 1.000 0.766 ! positive regulation of nuclease activity GO:0032075 66 66 0.000 1.000 1.000 1.000 1.000 0.730 ! negative regulation of protein binding GO:0032091 35 35 0.000 1.000 1.000 1.000 1.000 0.835 ! positive regulation of protein binding GO:0032092 41 41 0.000 1.000 1.000 1.000 1.000 0.807 ! regulation of response to extracellular stimulus GO:0032104 34 34 0.000 1.000 1.000 1.000 1.000 0.822 GO:0032107|regulation of response to nutrient levels, ! regulation of response to nutrient levels GO:0032107 34 34 0.000 1.000 1.000 1.000 1.000 0.822 GO:0032104|regulation of response to extracellular stimulus, ! telomere organization GO:0032200 59 59 0.000 1.000 1.000 1.000 1.000 0.839 ! telomere maintenance via semi-conservative replication GO:0032201 22 22 0.000 1.000 1.000 1.000 1.000 0.669 ! regulation of synaptic transmission, GABAergic GO:0032228 24 24 0.000 1.000 1.000 1.000 1.000 0.802 ! regulation of protein polymerization GO:0032271 109 108 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of protein polymerization GO:0032272 44 44 0.000 1.000 1.000 1.000 1.000 0.741 ! positive regulation of protein polymerization GO:0032273 52 51 0.000 1.000 1.000 1.000 1.000 0.821 ! regulation of ARF GTPase activity GO:0032312 32 32 0.000 1.000 1.000 1.000 1.000 0.00250 ! positive regulation of Ras GTPase activity GO:0032320 98 98 0.000 1.000 1.000 1.000 1.000 0.946 ! positive regulation of Rho GTPase activity GO:0032321 65 65 0.000 1.000 1.000 1.000 1.000 0.815 ! negative regulation of lipid transport GO:0032369 21 21 0.000 1.000 1.000 1.000 1.000 0.847 ! DNA geometric change GO:0032392 31 31 0.000 1.000 1.000 1.000 1.000 0.688 ! melanosome localization GO:0032400 21 21 0.000 1.000 1.000 1.000 1.000 0.734 ! negative regulation of transporter activity GO:0032410 22 22 0.000 1.000 1.000 1.000 1.000 0.800 ! regulation of protein oligomerization GO:0032459 21 21 0.000 1.000 1.000 1.000 1.000 0.734 ! regulation of cytokinesis GO:0032465 28 28 0.000 1.000 1.000 1.000 1.000 0.757 ! positive regulation of type I interferon production GO:0032481 36 36 0.000 1.000 1.000 1.000 1.000 0.807 ! DNA duplex unwinding GO:0032508 30 30 0.000 1.000 1.000 1.000 1.000 0.694 ! regulation of interferon-beta production GO:0032648 31 31 0.000 1.000 1.000 1.000 1.000 0.779 ! regulation of interleukin-4 production GO:0032673 24 24 0.000 1.000 1.000 1.000 1.000 0.821 ! positive regulation of chemokine production GO:0032722 30 30 0.000 1.000 1.000 1.000 1.000 0.876 ! positive regulation of interferon-beta production GO:0032728 22 22 0.000 1.000 1.000 1.000 1.000 0.706 ! positive regulation of interferon-gamma production GO:0032729 32 31 0.000 1.000 1.000 1.000 1.000 0.855 ! positive regulation of interleukin-1 beta production GO:0032731 23 23 0.000 1.000 1.000 1.000 1.000 0.819 ! positive regulation of interleukin-1 production GO:0032732 26 26 0.000 1.000 1.000 1.000 1.000 0.830 ! positive regulation of interleukin-12 production GO:0032735 24 24 0.000 1.000 1.000 1.000 1.000 0.847 ! positive regulation of interleukin-6 production GO:0032755 33 33 0.000 1.000 1.000 1.000 1.000 0.857 ! positive regulation of tumor necrosis factor production GO:0032760 31 31 0.000 1.000 1.000 1.000 1.000 0.867 ! regulation of monooxygenase activity GO:0032768 45 45 0.000 1.000 1.000 1.000 1.000 0.859 ! regulation of transcription elongation, DNA-dependent GO:0032784 37 35 0.000 1.000 1.000 1.000 1.000 0.582 ! positive regulation of homeostatic process GO:0032846 64 64 0.000 1.000 1.000 1.000 1.000 0.886 ! positive regulation of Rac GTPase activity GO:0032855 27 27 0.000 1.000 1.000 1.000 1.000 0.723 ! activation of Ras GTPase activity GO:0032856 28 28 0.000 1.000 1.000 1.000 1.000 0.760 ! activation of Rho GTPase activity GO:0032862 20 20 0.000 1.000 1.000 1.000 1.000 0.648 ! negative regulation of stress-activated MAPK cascade GO:0032873 26 26 0.000 1.000 1.000 1.000 1.000 0.744 GO:0070303|negative regulation of stress-activated protein kinase signaling cascade, ! positive regulation of stress-activated MAPK cascade GO:0032874 54 54 0.000 1.000 1.000 1.000 1.000 0.846 ! regulation of microtubule-based process GO:0032886 94 92 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of organic acid transport GO:0032890 30 30 0.000 1.000 1.000 1.000 1.000 0.856 ! regulation of collagen biosynthetic process GO:0032965 23 23 0.000 1.000 1.000 1.000 1.000 0.831 ! positive regulation of collagen biosynthetic process GO:0032967 20 20 0.000 1.000 1.000 1.000 1.000 0.814 GO:0010714|positive regulation of collagen metabolic process, ! regulation of mast cell activation GO:0033003 24 24 0.000 1.000 1.000 1.000 1.000 0.816 ! tetrapyrrole metabolic process GO:0033013 48 48 0.000 1.000 1.000 1.000 1.000 0.804 ! tetrapyrrole biosynthetic process GO:0033014 31 31 0.000 1.000 1.000 1.000 1.000 0.708 GO:0006779|porphyrin-containing compound biosynthetic process, ! cellular pigmentation GO:0033059 36 36 0.000 1.000 1.000 1.000 1.000 0.812 ! T cell differentiation in thymus GO:0033077 45 45 0.000 1.000 1.000 1.000 1.000 0.858 ! regulation of T cell differentiation in thymus GO:0033081 20 20 0.000 1.000 1.000 1.000 1.000 0.740 ! mitochondrial respiratory chain complex assembly GO:0033108 24 22 0.000 1.000 1.000 1.000 1.000 0.466 ! regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 44 44 0.000 1.000 1.000 1.000 1.000 0.830 ! negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 23 23 0.000 1.000 1.000 1.000 1.000 0.739 ! response to ATP GO:0033198 21 21 0.000 1.000 1.000 1.000 1.000 0.748 ! cell cycle cytokinesis GO:0033205 24 24 0.000 1.000 1.000 1.000 1.000 0.652 ! regulation of cellular amine metabolic process GO:0033238 73 73 0.000 1.000 1.000 1.000 1.000 0.858 ! multicellular organismal response to stress GO:0033555 52 52 0.000 1.000 1.000 1.000 1.000 0.868 ! transferrin transport GO:0033572 30 30 0.000 1.000 1.000 1.000 1.000 0.592 GO:0015682|ferric iron transport, ! response to glucagon stimulus GO:0033762 41 41 0.000 1.000 1.000 1.000 1.000 0.705 ! protein localization in Golgi apparatus GO:0034067 20 20 0.000 1.000 1.000 1.000 1.000 0.210 ! CenH3-containing nucleosome assembly at centromere GO:0034080 23 23 0.000 1.000 1.000 1.000 1.000 0.426 GO:0034724|DNA replication-independent nucleosome organization, GO:0006336|DNA replication-independent nucleosome assembly, ! positive regulation of tissue remodeling GO:0034105 20 20 0.000 1.000 1.000 1.000 1.000 0.821 ! macromolecular complex remodeling GO:0034367 23 23 0.000 1.000 1.000 1.000 1.000 0.827 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein-lipid complex remodeling GO:0034368 23 23 0.000 1.000 1.000 1.000 1.000 0.827 GO:0034367|macromolecular complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! plasma lipoprotein particle remodeling GO:0034369 23 23 0.000 1.000 1.000 1.000 1.000 0.827 GO:0034367|macromolecular complex remodeling, GO:0034368|protein-lipid complex remodeling, ! microtubule anchoring GO:0034453 26 26 0.000 1.000 1.000 1.000 1.000 0.719 ! protein localization to chromosome GO:0034502 24 23 0.000 1.000 1.000 1.000 1.000 0.766 ! cellular response to heat GO:0034605 22 22 0.000 1.000 1.000 1.000 1.000 0.393 ! DNA replication-independent nucleosome organization GO:0034724 23 23 0.000 1.000 1.000 1.000 1.000 0.426 GO:0034080|CenH3-containing nucleosome assembly at centromere, GO:0006336|DNA replication-independent nucleosome assembly, ! nucleosome organization GO:0034728 126 126 0.000 1.000 1.000 1.000 1.000 0.425 ! regulation of Rac protein signal transduction GO:0035020 24 24 0.000 1.000 1.000 1.000 1.000 0.696 ! regulation of histone acetylation GO:0035065 28 28 0.000 1.000 1.000 1.000 1.000 0.814 ! establishment or maintenance of apical/basal cell polarity GO:0035088 21 21 0.000 1.000 1.000 1.000 1.000 0.707 GO:0061245|establishment or maintenance of bipolar cell polarity, ! embryonic forelimb morphogenesis GO:0035115 29 29 0.000 1.000 1.000 1.000 1.000 0.749 ! embryonic hindlimb morphogenesis GO:0035116 29 29 0.000 1.000 1.000 1.000 1.000 0.809 ! forelimb morphogenesis GO:0035136 37 37 0.000 1.000 1.000 1.000 1.000 0.766 ! hindlimb morphogenesis GO:0035137 38 38 0.000 1.000 1.000 1.000 1.000 0.819 ! social behavior GO:0035176 33 33 0.000 1.000 1.000 1.000 1.000 0.811 ! posttranscriptional gene silencing by RNA GO:0035194 33 29 0.000 1.000 1.000 1.000 1.000 0.773 GO:0016441|posttranscriptional gene silencing, ! gene silencing by miRNA GO:0035195 28 24 0.000 1.000 1.000 1.000 1.000 0.731 ! synaptic transmission, glutamatergic GO:0035249 20 20 0.000 1.000 1.000 1.000 1.000 0.675 ! organ growth GO:0035265 33 32 0.000 1.000 1.000 1.000 1.000 0.859 ! hippo signaling cascade GO:0035329 24 24 0.000 1.000 1.000 1.000 1.000 0.277 ! long-chain fatty-acyl-CoA metabolic process GO:0035336 24 24 0.000 1.000 1.000 1.000 1.000 0.762 ! fatty-acyl-CoA metabolic process GO:0035337 27 27 0.000 1.000 1.000 1.000 1.000 0.773 ! thioester metabolic process GO:0035383 40 40 0.000 1.000 1.000 1.000 1.000 0.802 GO:0006637|acyl-CoA metabolic process, ! thioester biosynthetic process GO:0035384 20 20 0.000 1.000 1.000 1.000 1.000 0.724 GO:0046949|fatty-acyl-CoA biosynthetic process, GO:0071616|acyl-CoA biosynthetic process, ! regulation of catenin import into nucleus GO:0035412 22 22 0.000 1.000 1.000 1.000 1.000 0.776 ! non-canonical Wnt receptor signaling pathway GO:0035567 32 32 0.000 1.000 1.000 1.000 1.000 0.850 ! CD4-positive, alpha-beta T cell activation GO:0035710 22 22 0.000 1.000 1.000 1.000 1.000 0.813 ! reciprocal DNA recombination GO:0035825 36 36 0.000 1.000 1.000 1.000 1.000 0.755 GO:0007131|reciprocal meiotic recombination, ! skeletal muscle cell differentiation GO:0035914 37 36 0.000 1.000 1.000 1.000 1.000 0.800 ! replacement ossification GO:0036075 22 22 0.000 1.000 1.000 1.000 1.000 0.708 GO:0001958|endochondral ossification, ! positive regulation of multicellular organism growth GO:0040018 29 29 0.000 1.000 1.000 1.000 1.000 0.855 ! regulation of meiosis GO:0040020 22 22 0.000 1.000 1.000 1.000 1.000 0.710 ! regulation of gene expression, epigenetic GO:0040029 127 123 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 62 62 0.000 1.000 1.000 1.000 1.000 0.825 ! negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 39 39 0.000 1.000 1.000 1.000 1.000 0.705 ! positive regulation of cytokine biosynthetic process GO:0042108 59 59 0.000 1.000 1.000 1.000 1.000 0.881 ! macrophage activation GO:0042116 20 20 0.000 1.000 1.000 1.000 1.000 0.768 ! retrograde transport, endosome to Golgi GO:0042147 37 37 0.000 1.000 1.000 1.000 1.000 0.283 ! heme metabolic process GO:0042168 30 30 0.000 1.000 1.000 1.000 1.000 0.729 ! negative regulation of protein catabolic process GO:0042177 43 43 0.000 1.000 1.000 1.000 1.000 0.807 ! response to cocaine GO:0042220 31 31 0.000 1.000 1.000 1.000 1.000 0.858 GO:0014073|response to tropane, ! ribosome biogenesis GO:0042254 150 150 0.000 1.000 1.000 1.000 1.000 0.571 ! purine nucleoside metabolic process GO:0042278 48 47 0.000 1.000 1.000 1.000 1.000 0.831 ! regulation of fatty acid biosynthetic process GO:0042304 29 29 0.000 1.000 1.000 1.000 1.000 0.833 ! positive regulation of protein import into nucleus GO:0042307 65 65 0.000 1.000 1.000 1.000 1.000 0.885 ! vasodilation GO:0042311 26 26 0.000 1.000 1.000 1.000 1.000 0.822 ! regulation of NF-kappaB import into nucleus GO:0042345 36 36 0.000 1.000 1.000 1.000 1.000 0.843 ! positive regulation of NF-kappaB import into nucleus GO:0042346 21 21 0.000 1.000 1.000 1.000 1.000 0.810 ! cilium assembly GO:0042384 79 79 0.000 1.000 1.000 1.000 1.000 0.643 ! cellular modified amino acid biosynthetic process GO:0042398 42 42 0.000 1.000 1.000 1.000 1.000 0.754 ! cellular biogenic amine biosynthetic process GO:0042401 46 46 0.000 1.000 1.000 1.000 1.000 0.842 ! cellular biogenic amine catabolic process GO:0042402 24 24 0.000 1.000 1.000 1.000 1.000 0.798 ! indole-containing compound metabolic process GO:0042430 22 22 0.000 1.000 1.000 1.000 1.000 0.767 GO:0006586|indolalkylamine metabolic process, ! ethanolamine-containing compound metabolic process GO:0042439 52 52 0.000 1.000 1.000 1.000 1.000 0.805 ! pigment metabolic process GO:0042440 60 60 0.000 1.000 1.000 1.000 1.000 0.859 ! inner ear morphogenesis GO:0042472 95 95 0.000 1.000 1.000 1.000 1.000 0.946 ! retinoic acid metabolic process GO:0042573 21 21 0.000 1.000 1.000 1.000 1.000 0.725 ! fear response GO:0042596 23 23 0.000 1.000 1.000 1.000 1.000 0.770 ! embryonic digit morphogenesis GO:0042733 46 46 0.000 1.000 1.000 1.000 1.000 0.827 ! hydrogen peroxide metabolic process GO:0042743 29 29 0.000 1.000 1.000 1.000 1.000 0.771 ! hydrogen peroxide catabolic process GO:0042744 20 20 0.000 1.000 1.000 1.000 1.000 0.639 ! eating behavior GO:0042755 22 22 0.000 1.000 1.000 1.000 1.000 0.732 ! ATP synthesis coupled electron transport GO:0042773 52 52 0.000 1.000 1.000 1.000 1.000 0.591 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! mitochondrial ATP synthesis coupled electron transport GO:0042775 52 52 0.000 1.000 1.000 1.000 1.000 0.591 GO:0042773|ATP synthesis coupled electron transport, ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:0042787 48 47 0.000 1.000 1.000 1.000 1.000 0.151 ! positive regulation of transcription factor import into nucleus GO:0042993 32 32 0.000 1.000 1.000 1.000 1.000 0.839 ! T cell homeostasis GO:0043029 25 25 0.000 1.000 1.000 1.000 1.000 0.823 ! regulation of macrophage activation GO:0043030 23 23 0.000 1.000 1.000 1.000 1.000 0.789 ! amino acid activation GO:0043038 51 51 0.000 1.000 1.000 1.000 1.000 0.796 GO:0043039|tRNA aminoacylation, ! tRNA aminoacylation GO:0043039 51 51 0.000 1.000 1.000 1.000 1.000 0.796 GO:0043038|amino acid activation, ! peptide biosynthetic process GO:0043043 27 27 0.000 1.000 1.000 1.000 1.000 0.562 ! ATP-dependent chromatin remodeling GO:0043044 32 32 0.000 1.000 1.000 1.000 1.000 0.582 ! cellular metabolic compound salvage GO:0043094 35 35 0.000 1.000 1.000 1.000 1.000 0.842 ! receptor clustering GO:0043113 23 23 0.000 1.000 1.000 1.000 1.000 0.772 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 180 180 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of protein complex disassembly GO:0043242 46 46 0.000 1.000 1.000 1.000 1.000 0.756 ! regulation of potassium ion transport GO:0043266 25 25 0.000 1.000 1.000 1.000 1.000 0.729 ! negative regulation of ion transport GO:0043271 38 38 0.000 1.000 1.000 1.000 1.000 0.856 ! response to morphine GO:0043278 21 21 0.000 1.000 1.000 1.000 1.000 0.770 ! apical junction assembly GO:0043297 39 39 0.000 1.000 1.000 1.000 1.000 0.546 ! leukocyte degranulation GO:0043299 22 22 0.000 1.000 1.000 1.000 1.000 0.761 ! regulation of leukocyte degranulation GO:0043300 21 21 0.000 1.000 1.000 1.000 1.000 0.800 ! response to exogenous dsRNA GO:0043330 21 21 0.000 1.000 1.000 1.000 1.000 0.726 ! response to dsRNA GO:0043331 39 38 0.000 1.000 1.000 1.000 1.000 0.822 ! CD4-positive, alpha-beta T cell differentiation GO:0043367 21 21 0.000 1.000 1.000 1.000 1.000 0.805 ! negative regulation of DNA binding GO:0043392 37 37 0.000 1.000 1.000 1.000 1.000 0.825 ! regulation of protein binding GO:0043393 97 97 0.000 1.000 1.000 1.000 1.000 0.946 ! cellular alkene metabolic process GO:0043449 35 35 0.000 1.000 1.000 1.000 1.000 0.737 ! alkene biosynthetic process GO:0043450 28 28 0.000 1.000 1.000 1.000 1.000 0.645 GO:0019370|leukotriene biosynthetic process, ! pigmentation GO:0043473 84 84 0.000 1.000 1.000 1.000 1.000 0.872 ! regulation of RNA splicing GO:0043484 62 62 0.000 1.000 1.000 1.000 1.000 0.393 ! histone exchange GO:0043486 27 27 0.000 1.000 1.000 1.000 1.000 0.497 ! regulation of RNA stability GO:0043487 41 41 0.000 1.000 1.000 1.000 1.000 0.702 ! regulation of mRNA stability GO:0043488 37 37 0.000 1.000 1.000 1.000 1.000 0.681 ! RNA stabilization GO:0043489 26 26 0.000 1.000 1.000 1.000 1.000 0.674 GO:0048255|mRNA stabilization, ! muscle adaptation GO:0043500 21 21 0.000 1.000 1.000 1.000 1.000 0.782 ! regulation of DNA damage response, signal transduction by p53 class mediator GO:0043516 25 25 0.000 1.000 1.000 1.000 1.000 0.765 ! positive regulation of neuron apoptosis GO:0043525 40 40 0.000 1.000 1.000 1.000 1.000 0.843 ! protein acylation GO:0043543 121 121 0.000 1.000 1.000 1.000 1.000 0.946 ! peroxisomal transport GO:0043574 20 20 0.000 1.000 1.000 1.000 1.000 0.643 ! cellular amide metabolic process GO:0043603 23 23 0.000 1.000 1.000 1.000 1.000 0.771 ! RNA polyadenylation GO:0043631 25 25 0.000 1.000 1.000 1.000 1.000 0.537 ! negative regulation of multi-organism process GO:0043901 23 23 0.000 1.000 1.000 1.000 1.000 0.825 ! regulation of symbiosis, encompassing mutualism through parasitism GO:0043903 23 23 0.000 1.000 1.000 1.000 1.000 0.813 ! modulation by host of viral transcription GO:0043921 20 20 0.000 1.000 1.000 1.000 1.000 0.769 GO:0052472|modulation by host of symbiont transcription, ! exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay GO:0043928 26 26 0.000 1.000 1.000 1.000 1.000 0.296 GO:0000291|nuclear-transcribed mRNA catabolic process, exonucleolytic, ! cellular component maintenance GO:0043954 39 39 0.000 1.000 1.000 1.000 1.000 0.732 ! histone H3 acetylation GO:0043966 42 42 0.000 1.000 1.000 1.000 1.000 0.691 ! histone H4 acetylation GO:0043967 41 41 0.000 1.000 1.000 1.000 1.000 0.730 ! regulation of digestive system process GO:0044058 25 25 0.000 1.000 1.000 1.000 1.000 0.835 ! positive regulation of cellular component biogenesis GO:0044089 21 21 0.000 1.000 1.000 1.000 1.000 0.721 ! regulation of multicellular organismal metabolic process GO:0044246 31 31 0.000 1.000 1.000 1.000 1.000 0.856 ! positive regulation of multicellular organismal metabolic process GO:0044253 26 26 0.000 1.000 1.000 1.000 1.000 0.840 ! glycerol ether catabolic process GO:0044269 20 20 0.000 1.000 1.000 1.000 1.000 0.710 GO:0046464|acylglycerol catabolic process, GO:0046461|neutral lipid catabolic process, ! DNA excision GO:0044349 21 21 0.000 1.000 1.000 1.000 1.000 0.653 GO:0000718|nucleotide-excision repair, DNA damage removal, ! regulated secretory pathway GO:0045055 29 29 0.000 1.000 1.000 1.000 1.000 0.778 ! T cell selection GO:0045058 25 25 0.000 1.000 1.000 1.000 1.000 0.804 ! regulation of viral genome replication GO:0045069 48 48 0.000 1.000 1.000 1.000 1.000 0.813 ! negative regulation of viral genome replication GO:0045071 32 32 0.000 1.000 1.000 1.000 1.000 0.740 ! intermediate filament-based process GO:0045103 30 30 0.000 1.000 1.000 1.000 1.000 0.591 ! intermediate filament cytoskeleton organization GO:0045104 29 29 0.000 1.000 1.000 1.000 1.000 0.605 ! meiotic chromosome segregation GO:0045132 22 21 0.000 1.000 1.000 1.000 1.000 0.694 ! myoblast differentiation GO:0045445 22 22 0.000 1.000 1.000 1.000 1.000 0.734 ! bone resorption GO:0045453 20 20 0.000 1.000 1.000 1.000 1.000 0.722 ! cell redox homeostasis GO:0045454 57 57 0.000 1.000 1.000 1.000 1.000 0.480 ! photoreceptor cell maintenance GO:0045494 26 26 0.000 1.000 1.000 1.000 1.000 0.581 ! positive regulation of T cell differentiation GO:0045582 53 53 0.000 1.000 1.000 1.000 1.000 0.882 ! positive regulation of neuron differentiation GO:0045666 65 65 0.000 1.000 1.000 1.000 1.000 0.852 ! regulation of osteoblast differentiation GO:0045667 98 98 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of osteoblast differentiation GO:0045668 34 34 0.000 1.000 1.000 1.000 1.000 0.809 ! positive regulation of osteoblast differentiation GO:0045669 56 56 0.000 1.000 1.000 1.000 1.000 0.871 ! regulation of osteoclast differentiation GO:0045670 40 40 0.000 1.000 1.000 1.000 1.000 0.805 ! positive regulation of DNA repair GO:0045739 27 27 0.000 1.000 1.000 1.000 1.000 0.736 ! regulation of adenylate cyclase activity GO:0045761 107 107 0.000 1.000 1.000 1.000 1.000 0.946 ! positive regulation of adenylate cyclase activity GO:0045762 65 65 0.000 1.000 1.000 1.000 1.000 0.861 ! positive regulation of ossification GO:0045778 39 39 0.000 1.000 1.000 1.000 1.000 0.869 ! negative regulation of endocytosis GO:0045806 26 26 0.000 1.000 1.000 1.000 1.000 0.737 ! negative regulation of gene expression, epigenetic GO:0045814 25 25 0.000 1.000 1.000 1.000 1.000 0.718 ! negative regulation of mitosis GO:0045839 39 39 0.000 1.000 1.000 1.000 1.000 0.782 GO:0051784|negative regulation of nuclear division, ! negative regulation of mitotic metaphase/anaphase transition GO:0045841 32 32 0.000 1.000 1.000 1.000 1.000 0.729 ! negative regulation of proteolysis GO:0045861 37 37 0.000 1.000 1.000 1.000 1.000 0.789 ! negative regulation of smoothened signaling pathway GO:0045879 20 20 0.000 1.000 1.000 1.000 1.000 0.613 ! positive regulation of exocytosis GO:0045921 34 34 0.000 1.000 1.000 1.000 1.000 0.792 ! positive regulation of steroid metabolic process GO:0045940 20 20 0.000 1.000 1.000 1.000 1.000 0.853 ! purine ribonucleoside metabolic process GO:0046128 44 44 0.000 1.000 1.000 1.000 1.000 0.843 ! pyrimidine ribonucleoside metabolic process GO:0046131 34 34 0.000 1.000 1.000 1.000 1.000 0.833 ! pyrimidine nucleoside catabolic process GO:0046135 20 20 0.000 1.000 1.000 1.000 1.000 0.747 ! pigment biosynthetic process GO:0046148 47 47 0.000 1.000 1.000 1.000 1.000 0.831 ! nitric oxide metabolic process GO:0046209 26 26 0.000 1.000 1.000 1.000 1.000 0.735 ! negative regulation of JNK cascade GO:0046329 21 21 0.000 1.000 1.000 1.000 1.000 0.690 ! positive regulation of JNK cascade GO:0046330 49 49 0.000 1.000 1.000 1.000 1.000 0.846 ! diacylglycerol metabolic process GO:0046339 24 24 0.000 1.000 1.000 1.000 1.000 0.619 ! neutral lipid biosynthetic process GO:0046460 47 47 0.000 1.000 1.000 1.000 1.000 0.826 GO:0046463|acylglycerol biosynthetic process, ! neutral lipid catabolic process GO:0046461 20 20 0.000 1.000 1.000 1.000 1.000 0.710 GO:0044269|glycerol ether catabolic process, GO:0046464|acylglycerol catabolic process, ! acylglycerol biosynthetic process GO:0046463 47 47 0.000 1.000 1.000 1.000 1.000 0.826 GO:0046460|neutral lipid biosynthetic process, ! acylglycerol catabolic process GO:0046464 20 20 0.000 1.000 1.000 1.000 1.000 0.710 GO:0044269|glycerol ether catabolic process, GO:0046461|neutral lipid catabolic process, ! membrane lipid catabolic process GO:0046466 21 21 0.000 1.000 1.000 1.000 1.000 0.732 ! membrane lipid biosynthetic process GO:0046467 60 60 0.000 1.000 1.000 1.000 1.000 0.745 ! phosphatidylcholine metabolic process GO:0046470 36 36 0.000 1.000 1.000 1.000 1.000 0.736 ! phosphatidic acid metabolic process GO:0046473 31 31 0.000 1.000 1.000 1.000 1.000 0.661 GO:0006654|phosphatidic acid biosynthetic process, ! nicotinamide nucleotide metabolic process GO:0046496 48 48 0.000 1.000 1.000 1.000 1.000 0.834 GO:0019362|pyridine nucleotide metabolic process, ! glycerolipid catabolic process GO:0046503 26 26 0.000 1.000 1.000 1.000 1.000 0.743 ! glycerol ether biosynthetic process GO:0046504 52 52 0.000 1.000 1.000 1.000 1.000 0.838 ! ceramide biosynthetic process GO:0046513 22 22 0.000 1.000 1.000 1.000 1.000 0.635 ! sphingoid metabolic process GO:0046519 66 66 0.000 1.000 1.000 1.000 1.000 0.816 ! sphingoid biosynthetic process GO:0046520 27 27 0.000 1.000 1.000 1.000 1.000 0.697 ! positive regulation of Ras protein signal transduction GO:0046579 26 26 0.000 1.000 1.000 1.000 1.000 0.763 ! alpha-beta T cell activation GO:0046631 40 40 0.000 1.000 1.000 1.000 1.000 0.862 ! alpha-beta T cell differentiation GO:0046632 35 35 0.000 1.000 1.000 1.000 1.000 0.848 ! positive regulation of alpha-beta T cell activation GO:0046635 43 43 0.000 1.000 1.000 1.000 1.000 0.877 ! positive regulation of alpha-beta T cell differentiation GO:0046638 30 30 0.000 1.000 1.000 1.000 1.000 0.852 ! negative regulation of insulin secretion GO:0046676 26 26 0.000 1.000 1.000 1.000 1.000 0.778 ! response to antibiotic GO:0046677 39 38 0.000 1.000 1.000 1.000 1.000 0.820 ! response to cadmium ion GO:0046686 33 33 0.000 1.000 1.000 1.000 1.000 0.800 ! acid secretion GO:0046717 20 20 0.000 1.000 1.000 1.000 1.000 0.773 ! regulation of viral transcription GO:0046782 72 68 0.000 1.000 1.000 1.000 1.000 0.823 ! lipid phosphorylation GO:0046834 23 23 0.000 1.000 1.000 1.000 1.000 0.672 ! phosphatidylinositol phosphorylation GO:0046854 22 22 0.000 1.000 1.000 1.000 1.000 0.671 ! positive regulation of lipid biosynthetic process GO:0046889 41 41 0.000 1.000 1.000 1.000 1.000 0.876 ! regulation of neurotransmitter secretion GO:0046928 31 31 0.000 1.000 1.000 1.000 1.000 0.765 ! fatty-acyl-CoA biosynthetic process GO:0046949 20 20 0.000 1.000 1.000 1.000 1.000 0.724 GO:0035384|thioester biosynthetic process, GO:0071616|acyl-CoA biosynthetic process, ! ephrin receptor signaling pathway GO:0048013 25 25 0.000 1.000 1.000 1.000 1.000 0.590 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 37 37 0.000 1.000 1.000 1.000 1.000 0.522 ! embryonic eye morphogenesis GO:0048048 31 31 0.000 1.000 1.000 1.000 1.000 0.849 ! developmental pigmentation GO:0048066 40 40 0.000 1.000 1.000 1.000 1.000 0.821 ! negative regulation of fibroblast proliferation GO:0048147 24 24 0.000 1.000 1.000 1.000 1.000 0.729 ! regulation of synaptic plasticity GO:0048167 90 89 0.000 1.000 1.000 1.000 1.000 0.882 ! regulation of neuronal synaptic plasticity GO:0048168 40 39 0.000 1.000 1.000 1.000 1.000 0.809 ! regulation of long-term neuronal synaptic plasticity GO:0048169 24 24 0.000 1.000 1.000 1.000 1.000 0.763 ! mRNA stabilization GO:0048255 26 26 0.000 1.000 1.000 1.000 1.000 0.674 GO:0043489|RNA stabilization, ! response to pain GO:0048265 27 27 0.000 1.000 1.000 1.000 1.000 0.801 ! vesicle docking GO:0048278 27 27 0.000 1.000 1.000 1.000 1.000 0.529 ! organelle fusion GO:0048284 42 41 0.000 1.000 1.000 1.000 1.000 0.726 ! lung alveolus development GO:0048286 37 37 0.000 1.000 1.000 1.000 1.000 0.843 ! regulation of retinoic acid receptor signaling pathway GO:0048385 39 38 0.000 1.000 1.000 1.000 1.000 0.0919 ! negative regulation of retinoic acid receptor signaling pathway GO:0048387 34 33 0.000 1.000 1.000 1.000 1.000 0.00764 ! enteric nervous system development GO:0048484 21 21 0.000 1.000 1.000 1.000 1.000 0.736 ! synaptic vesicle endocytosis GO:0048488 20 20 0.000 1.000 1.000 1.000 1.000 0.574 ! synaptic vesicle transport GO:0048489 63 63 0.000 1.000 1.000 1.000 1.000 0.812 ! negative regulation of behavior GO:0048521 30 30 0.000 1.000 1.000 1.000 1.000 0.861 ! positive regulation of viral reproduction GO:0048524 87 83 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of viral reproduction GO:0048525 33 33 0.000 1.000 1.000 1.000 1.000 0.751 ! spleen development GO:0048536 26 26 0.000 1.000 1.000 1.000 1.000 0.715 ! developmental cell growth GO:0048588 38 38 0.000 1.000 1.000 1.000 1.000 0.814 ! embryonic camera-type eye morphogenesis GO:0048596 26 26 0.000 1.000 1.000 1.000 1.000 0.843 ! negative regulation of developmental growth GO:0048640 27 27 0.000 1.000 1.000 1.000 1.000 0.810 ! organ formation GO:0048645 28 28 0.000 1.000 1.000 1.000 1.000 0.835 ! neuron fate specification GO:0048665 25 25 0.000 1.000 1.000 1.000 1.000 0.740 ! axon extension GO:0048675 25 25 0.000 1.000 1.000 1.000 1.000 0.724 ! embryonic cranial skeleton morphogenesis GO:0048701 35 35 0.000 1.000 1.000 1.000 1.000 0.840 ! astrocyte differentiation GO:0048708 22 22 0.000 1.000 1.000 1.000 1.000 0.790 ! oligodendrocyte differentiation GO:0048709 51 49 0.000 1.000 1.000 1.000 1.000 0.864 ! genitalia development GO:0048806 36 36 0.000 1.000 1.000 1.000 1.000 0.832 ! regulation of dendrite morphogenesis GO:0048814 41 40 0.000 1.000 1.000 1.000 1.000 0.811 ! brain morphogenesis GO:0048854 28 28 0.000 1.000 1.000 1.000 1.000 0.815 ! homeostasis of number of cells within a tissue GO:0048873 23 23 0.000 1.000 1.000 1.000 1.000 0.649 ! chromosome localization GO:0050000 22 21 0.000 1.000 1.000 1.000 1.000 0.698 ! regulation of catecholamine secretion GO:0050433 30 30 0.000 1.000 1.000 1.000 1.000 0.856 ! positive regulation of viral transcription GO:0050434 59 55 0.000 1.000 1.000 1.000 1.000 0.760 ! nucleic acid transport GO:0050657 130 130 0.000 1.000 1.000 1.000 1.000 0.754 GO:0051236|establishment of RNA localization, GO:0050658|RNA transport, ! RNA transport GO:0050658 130 130 0.000 1.000 1.000 1.000 1.000 0.754 GO:0051236|establishment of RNA localization, GO:0050657|nucleic acid transport, ! regulation of mRNA processing GO:0050684 49 49 0.000 1.000 1.000 1.000 1.000 0.652 ! regulation of defense response to virus by virus GO:0050690 28 28 0.000 1.000 1.000 1.000 1.000 0.634 ! positive regulation of cytokine secretion GO:0050715 56 56 0.000 1.000 1.000 1.000 1.000 0.866 ! negative regulation of axonogenesis GO:0050771 41 41 0.000 1.000 1.000 1.000 1.000 0.813 ! regulation of viral reproduction GO:0050792 117 113 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of synapse structure and activity GO:0050803 54 54 0.000 1.000 1.000 1.000 1.000 0.857 ! negative regulation of synaptic transmission GO:0050805 28 28 0.000 1.000 1.000 1.000 1.000 0.812 ! positive regulation of synaptic transmission GO:0050806 53 53 0.000 1.000 1.000 1.000 1.000 0.879 ! regulation of synapse organization GO:0050807 50 50 0.000 1.000 1.000 1.000 1.000 0.848 ! defense response to Gram-positive bacterium GO:0050830 33 33 0.000 1.000 1.000 1.000 1.000 0.842 ! defense response to fungus GO:0050832 21 21 0.000 1.000 1.000 1.000 1.000 0.349 ! regulation of calcium-mediated signaling GO:0050848 35 35 0.000 1.000 1.000 1.000 1.000 0.801 ! positive regulation of calcium-mediated signaling GO:0050850 24 24 0.000 1.000 1.000 1.000 1.000 0.760 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 26 26 0.000 1.000 1.000 1.000 1.000 0.769 ! regulation of T cell receptor signaling pathway GO:0050856 20 20 0.000 1.000 1.000 1.000 1.000 0.714 ! multicellular organismal movement GO:0050879 22 22 0.000 1.000 1.000 1.000 1.000 0.648 GO:0050881|musculoskeletal movement, ! musculoskeletal movement GO:0050881 22 22 0.000 1.000 1.000 1.000 1.000 0.648 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling balance GO:0050885 47 47 0.000 1.000 1.000 1.000 1.000 0.826 ! neuromuscular process GO:0050905 83 83 0.000 1.000 1.000 1.000 1.000 0.875 ! detection of stimulus involved in sensory perception GO:0050906 95 95 0.000 1.000 1.000 1.000 1.000 0.593 ! detection of chemical stimulus involved in sensory perception GO:0050907 60 60 0.000 1.000 1.000 1.000 1.000 0.00429 ! sensory perception of taste GO:0050909 49 49 0.000 1.000 1.000 1.000 1.000 0.163 ! detection of chemical stimulus involved in sensory perception of smell GO:0050911 36 36 0.000 1.000 1.000 1.000 1.000 0.000858 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 22 22 0.000 1.000 1.000 1.000 1.000 0.256 ! negative regulation of chemotaxis GO:0050922 22 22 0.000 1.000 1.000 1.000 1.000 0.819 ! pigment cell differentiation GO:0050931 30 30 0.000 1.000 1.000 1.000 1.000 0.775 ! sensory perception of mechanical stimulus GO:0050954 136 136 0.000 1.000 1.000 1.000 1.000 0.946 ! detection of mechanical stimulus involved in sensory perception GO:0050974 20 20 0.000 1.000 1.000 1.000 1.000 0.737 ! detection of mechanical stimulus GO:0050982 27 27 0.000 1.000 1.000 1.000 1.000 0.812 ! regulation of lipid catabolic process GO:0050994 42 42 0.000 1.000 1.000 1.000 1.000 0.870 ! regulation of nitric-oxide synthase activity GO:0050999 35 35 0.000 1.000 1.000 1.000 1.000 0.818 ! mRNA transport GO:0051028 114 114 0.000 1.000 1.000 1.000 1.000 0.692 ! positive regulation of small GTPase mediated signal transduction GO:0051057 28 28 0.000 1.000 1.000 1.000 1.000 0.781 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 106 106 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of binding GO:0051100 74 74 0.000 1.000 1.000 1.000 1.000 0.880 ! negative regulation of muscle cell differentiation GO:0051148 35 35 0.000 1.000 1.000 1.000 1.000 0.809 ! cofactor transport GO:0051181 21 21 0.000 1.000 1.000 1.000 1.000 0.648 ! spindle assembly GO:0051225 40 40 0.000 1.000 1.000 1.000 1.000 0.641 ! establishment of RNA localization GO:0051236 130 130 0.000 1.000 1.000 1.000 1.000 0.754 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of release of sequestered calcium ion into cytosol GO:0051279 38 38 0.000 1.000 1.000 1.000 1.000 0.861 ! establishment of spindle localization GO:0051293 23 22 0.000 1.000 1.000 1.000 1.000 0.709 ! centrosome organization GO:0051297 51 51 0.000 1.000 1.000 1.000 1.000 0.651 ! establishment of chromosome localization GO:0051303 21 20 0.000 1.000 1.000 1.000 1.000 0.698 ! meiotic cell cycle GO:0051321 151 148 0.000 1.000 1.000 1.000 1.000 0.946 ! prophase GO:0051324 25 25 0.000 1.000 1.000 1.000 1.000 0.589 ! M phase of meiotic cell cycle GO:0051327 148 145 0.000 1.000 1.000 1.000 1.000 0.946 GO:0007126|meiosis, ! regulation of lyase activity GO:0051339 114 114 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of ligase activity GO:0051340 100 100 0.000 1.000 1.000 1.000 1.000 0.946 ! positive regulation of lyase activity GO:0051349 70 70 0.000 1.000 1.000 1.000 1.000 0.868 ! negative regulation of lyase activity GO:0051350 58 58 0.000 1.000 1.000 1.000 1.000 0.839 ! positive regulation of ligase activity GO:0051351 86 86 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of ligase activity GO:0051352 72 72 0.000 1.000 1.000 1.000 1.000 0.838 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of oxidoreductase activity GO:0051354 20 20 0.000 1.000 1.000 1.000 1.000 0.791 ! response to mineralocorticoid stimulus GO:0051385 21 21 0.000 1.000 1.000 1.000 1.000 0.780 ! negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051436 67 67 0.000 1.000 1.000 1.000 1.000 0.826 ! positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051437 72 72 0.000 1.000 1.000 1.000 1.000 0.833 ! regulation of ubiquitin-protein ligase activity GO:0051438 96 96 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051439 78 78 0.000 1.000 1.000 1.000 1.000 0.844 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 82 82 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of ubiquitin-protein ligase activity GO:0051444 72 72 0.000 1.000 1.000 1.000 1.000 0.838 GO:0051352|negative regulation of ligase activity, ! regulation of meiotic cell cycle GO:0051445 24 24 0.000 1.000 1.000 1.000 1.000 0.733 ! regulation of intracellular pH GO:0051453 23 23 0.000 1.000 1.000 1.000 1.000 0.735 ! regulation of filopodium assembly GO:0051489 33 31 0.000 1.000 1.000 1.000 1.000 0.751 ! positive regulation of filopodium assembly GO:0051491 24 22 0.000 1.000 1.000 1.000 1.000 0.696 ! negative regulation of cytoskeleton organization GO:0051494 75 75 0.000 1.000 1.000 1.000 1.000 0.844 ! regulation of neurotransmitter transport GO:0051588 39 39 0.000 1.000 1.000 1.000 1.000 0.822 ! response to electrical stimulus GO:0051602 27 26 0.000 1.000 1.000 1.000 1.000 0.800 ! spindle localization GO:0051653 25 24 0.000 1.000 1.000 1.000 1.000 0.733 ! actin filament capping GO:0051693 24 24 0.000 1.000 1.000 1.000 1.000 0.592 ! interaction with symbiont GO:0051702 30 30 0.000 1.000 1.000 1.000 1.000 0.838 ! behavioral interaction between organisms GO:0051705 57 57 0.000 1.000 1.000 1.000 1.000 0.858 ! negative regulation of nuclear division GO:0051784 39 39 0.000 1.000 1.000 1.000 1.000 0.782 GO:0045839|negative regulation of mitosis, ! modification by host of symbiont morphology or physiology GO:0051851 25 25 0.000 1.000 1.000 1.000 1.000 0.814 ! protein autoubiquitination GO:0051865 33 33 0.000 1.000 1.000 1.000 1.000 0.485 ! pigment granule localization GO:0051875 22 22 0.000 1.000 1.000 1.000 1.000 0.744 ! negative regulation of protein kinase B signaling cascade GO:0051898 21 21 0.000 1.000 1.000 1.000 1.000 0.789 ! regulation of amine transport GO:0051952 46 46 0.000 1.000 1.000 1.000 1.000 0.882 ! regulation of synapse assembly GO:0051963 31 31 0.000 1.000 1.000 1.000 1.000 0.813 ! regulation of synaptic transmission, glutamatergic GO:0051966 30 30 0.000 1.000 1.000 1.000 1.000 0.851 ! negative regulation of transmission of nerve impulse GO:0051970 32 32 0.000 1.000 1.000 1.000 1.000 0.831 ! positive regulation of transmission of nerve impulse GO:0051971 56 56 0.000 1.000 1.000 1.000 1.000 0.881 ! regulation of chromosome segregation GO:0051983 26 25 0.000 1.000 1.000 1.000 1.000 0.775 ! modulation of transcription in other organism involved in symbiotic interaction GO:0052312 21 21 0.000 1.000 1.000 1.000 1.000 0.781 ! modulation by host of symbiont transcription GO:0052472 20 20 0.000 1.000 1.000 1.000 1.000 0.769 GO:0043921|modulation by host of viral transcription, ! regulation of cardiac muscle tissue growth GO:0055021 30 30 0.000 1.000 1.000 1.000 1.000 0.863 ! regulation of cardiac muscle tissue development GO:0055024 41 41 0.000 1.000 1.000 1.000 1.000 0.878 ! iron ion homeostasis GO:0055072 88 88 0.000 1.000 1.000 1.000 1.000 0.768 ! retina development in camera-type eye GO:0060041 103 103 0.000 1.000 1.000 1.000 1.000 0.946 ! retina morphogenesis in camera-type eye GO:0060042 38 38 0.000 1.000 1.000 1.000 1.000 0.805 ! regulation of cardiac muscle cell proliferation GO:0060043 27 27 0.000 1.000 1.000 1.000 1.000 0.851 ! Wnt receptor signaling pathway, planar cell polarity pathway GO:0060071 21 21 0.000 1.000 1.000 1.000 1.000 0.793 GO:0090175|regulation of establishment of planar polarity, ! inner ear receptor cell development GO:0060119 24 24 0.000 1.000 1.000 1.000 1.000 0.750 ! cilium morphogenesis GO:0060271 107 107 0.000 1.000 1.000 1.000 1.000 0.663 ! regulation of type I interferon-mediated signaling pathway GO:0060338 34 34 0.000 1.000 1.000 1.000 1.000 0.581 ! JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 24 24 0.000 1.000 1.000 1.000 1.000 0.738 ! lung morphogenesis GO:0060425 37 37 0.000 1.000 1.000 1.000 1.000 0.866 ! lung epithelium development GO:0060428 26 26 0.000 1.000 1.000 1.000 1.000 0.818 ! epithelial tube branching involved in lung morphogenesis GO:0060441 22 22 0.000 1.000 1.000 1.000 1.000 0.806 ! mammary gland morphogenesis GO:0060443 47 47 0.000 1.000 1.000 1.000 1.000 0.873 ! branching involved in mammary gland duct morphogenesis GO:0060444 23 23 0.000 1.000 1.000 1.000 1.000 0.824 ! regulation of cell projection assembly GO:0060491 61 58 0.000 1.000 1.000 1.000 1.000 0.844 ! prostate gland morphogenesis GO:0060512 28 28 0.000 1.000 1.000 1.000 1.000 0.832 ! mammary gland duct morphogenesis GO:0060603 34 34 0.000 1.000 1.000 1.000 1.000 0.861 ! adipose tissue development GO:0060612 22 22 0.000 1.000 1.000 1.000 1.000 0.765 ! prostate gland epithelium morphogenesis GO:0060740 26 26 0.000 1.000 1.000 1.000 1.000 0.843 ! regulation of androgen receptor signaling pathway GO:0060765 22 22 0.000 1.000 1.000 1.000 1.000 0.755 ! cell fate commitment involved in formation of primary germ layers GO:0060795 29 29 0.000 1.000 1.000 1.000 1.000 0.828 ! regulation of gene silencing GO:0060968 21 21 0.000 1.000 1.000 1.000 1.000 0.714 ! regulation of dendritic spine development GO:0060998 25 25 0.000 1.000 1.000 1.000 1.000 0.792 ! somite development GO:0061053 68 68 0.000 1.000 1.000 1.000 1.000 0.871 ! regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 28 28 0.000 1.000 1.000 1.000 1.000 0.799 ! mammary gland epithelium development GO:0061180 60 60 0.000 1.000 1.000 1.000 1.000 0.885 ! establishment or maintenance of bipolar cell polarity GO:0061245 21 21 0.000 1.000 1.000 1.000 1.000 0.707 GO:0035088|establishment or maintenance of apical/basal cell polarity, ! determination of heart left/right asymmetry GO:0061371 47 47 0.000 1.000 1.000 1.000 1.000 0.874 ! regulation of extent of cell growth GO:0061387 46 46 0.000 1.000 1.000 1.000 1.000 0.832 ! protein-DNA complex assembly GO:0065004 127 127 0.000 1.000 1.000 1.000 1.000 0.462 ! positive regulation of biomineral tissue development GO:0070169 32 32 0.000 1.000 1.000 1.000 1.000 0.855 ! chromosome organization involved in meiosis GO:0070192 29 29 0.000 1.000 1.000 1.000 1.000 0.682 ! negative regulation of stress-activated protein kinase signaling cascade GO:0070303 26 26 0.000 1.000 1.000 1.000 1.000 0.744 GO:0032873|negative regulation of stress-activated MAPK cascade, ! positive regulation of stress-activated protein kinase signaling cascade GO:0070304 55 55 0.000 1.000 1.000 1.000 1.000 0.850 ! lens fiber cell differentiation GO:0070306 22 22 0.000 1.000 1.000 1.000 1.000 0.634 ! regulation of microtubule cytoskeleton organization GO:0070507 79 77 0.000 1.000 1.000 1.000 1.000 0.851 ! protein K63-linked ubiquitination GO:0070534 25 25 0.000 1.000 1.000 1.000 1.000 0.643 ! protein localization in mitochondrion GO:0070585 58 57 0.000 1.000 1.000 1.000 1.000 0.679 ! tight junction assembly GO:0070830 32 32 0.000 1.000 1.000 1.000 1.000 0.459 ! organelle assembly GO:0070925 104 103 0.000 1.000 1.000 1.000 1.000 0.946 ! protein K11-linked ubiquitination GO:0070979 26 26 0.000 1.000 1.000 1.000 1.000 0.526 ! DNA conformation change GO:0071103 186 185 0.000 1.000 1.000 1.000 1.000 0.746 ! spindle assembly checkpoint GO:0071173 31 31 0.000 1.000 1.000 1.000 1.000 0.717 ! mitotic cell cycle spindle checkpoint GO:0071174 33 33 0.000 1.000 1.000 1.000 1.000 0.718 ! cellular response to alkaloid GO:0071312 20 20 0.000 1.000 1.000 1.000 1.000 0.845 ! cellular response to dsRNA GO:0071359 22 21 0.000 1.000 1.000 1.000 1.000 0.720 ! cellular response to glucagon stimulus GO:0071377 34 34 0.000 1.000 1.000 1.000 1.000 0.593 ! cellular response to organic cyclic compound GO:0071407 42 42 0.000 1.000 1.000 1.000 1.000 0.873 ! cellular response to ionizing radiation GO:0071479 33 32 0.000 1.000 1.000 1.000 1.000 0.772 ! otic vesicle development GO:0071599 20 20 0.000 1.000 1.000 1.000 1.000 0.778 ! acyl-CoA biosynthetic process GO:0071616 20 20 0.000 1.000 1.000 1.000 1.000 0.724 GO:0035384|thioester biosynthetic process, GO:0046949|fatty-acyl-CoA biosynthetic process, ! protein-DNA complex subunit organization GO:0071824 142 142 0.000 1.000 1.000 1.000 1.000 0.596 ! ribonucleoprotein complex subunit organization GO:0071826 107 107 0.000 1.000 1.000 1.000 1.000 0.798 ! DNA biosynthetic process GO:0071897 20 20 0.000 1.000 1.000 1.000 1.000 0.596 ! mesenchyme morphogenesis GO:0072132 20 20 0.000 1.000 1.000 1.000 1.000 0.862 ! monocarboxylic acid catabolic process GO:0072329 68 68 0.000 1.000 1.000 1.000 1.000 0.855 ! organelle transport along microtubule GO:0072384 30 30 0.000 1.000 1.000 1.000 1.000 0.726 ! pyridine-containing compound metabolic process GO:0072524 49 49 0.000 1.000 1.000 1.000 1.000 0.837 ! pyrimidine-containing compound metabolic process GO:0072527 70 70 0.000 1.000 1.000 1.000 1.000 0.875 ! pyrimidine-containing compound biosynthetic process GO:0072528 38 38 0.000 1.000 1.000 1.000 1.000 0.843 ! pyrimidine-containing compound catabolic process GO:0072529 31 31 0.000 1.000 1.000 1.000 1.000 0.795 ! maintenance of protein localization to organelle GO:0072595 23 23 0.000 1.000 1.000 1.000 1.000 0.625 ! establishment of protein localization in mitochondrion GO:0072655 57 56 0.000 1.000 1.000 1.000 1.000 0.674 ! regulation of establishment of protein localization in plasma membrane GO:0090003 24 24 0.000 1.000 1.000 1.000 1.000 0.774 ! cochlea morphogenesis GO:0090103 21 21 0.000 1.000 1.000 1.000 1.000 0.808 ! regulation of establishment of planar polarity GO:0090175 21 21 0.000 1.000 1.000 1.000 1.000 0.793 GO:0060071|Wnt receptor signaling pathway, planar cell polarity pathway, ! negative regulation of peptide hormone secretion GO:0090278 29 29 0.000 1.000 1.000 1.000 1.000 0.808 ! regulation of DNA-dependent DNA replication GO:0090329 26 26 0.000 1.000 1.000 1.000 1.000 0.792 ! phagosome maturation GO:0090382 46 46 0.000 1.000 1.000 1.000 1.000 0.774 ! cellular senescence GO:0090398 28 28 0.000 1.000 1.000 1.000 1.000 0.808 ! regulation of fatty acid transport GO:2000191 22 22 0.000 1.000 1.000 1.000 1.000 0.828 ! negative regulation of reproductive process GO:2000242 66 66 0.000 1.000 1.000 1.000 1.000 0.866 ! regulation of protein activation cascade GO:2000257 20 20 0.000 1.000 1.000 1.000 1.000 0.524 GO:0030449|regulation of complement activation, ! positive regulation of response to DNA damage stimulus GO:2001022 46 46 0.000 1.000 1.000 1.000 1.000 0.813 ! regulation of extrinsic apoptotic signaling pathway GO:2001236 28 28 0.000 1.000 1.000 1.000 1.000 0.726 ! positive regulation of chromosome organization GO:2001252 43 43 0.000 1.000 1.000 1.000 1.000 0.872 !#====== End run =======